Gene ADCK5 (Human)

ADCK5

Species: Human
Alias: FLJ35454, ADCK5, MGC126708
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 8q24.3,

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-D

Sequence

Name Sequence Type Origin Length Description Download
ADCK5.AA Protein Sugen Kinome 580 None Fasta, JSON
ADCK5.NA RNA Sugen Kinome 1977 None Fasta, JSON
ADCK5.kin_dom Protein Kinase Domain None 304 None Fasta, JSON

Protein domain

Protein domains of ADCK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK5.AA ABC1-B 188-304 46 6e-72 245.33 In-house 1-125 (125) Show / Hide 
Range on Protein: 188-304
Range on HMM: 1-125/125
Sequence Identity: 46% (58 aa)

EDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHP------SFGFSWVLQDLKGTLAQELDFENE
.|    . . | |||..||||||||||||||||||..||||||...||..|..|....||.........|      .|.|.|........|.|||||.||
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYNE

GRNAERCARELA---HFPYVVVPRVH
.||||.|.....   ||....|||.|
ARNAEKCRQMFKKFKHFDFLYVPRIH
Kinase ADCK5.AA ABC1 188-304 40 4e-64 219.36 In-house 1-123 (123) Show / Hide 
Range on Protein: 188-304
Range on HMM: 1-123/123
Sequence Identity: 40% (50 aa)

EDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHP-----SFGFSWVLQDLKGTLAQELDFENEG
.|    . . |.|||..|.||||.||||||||.||..||||||....|.....||...|..........|     .| ..|...... .|..|.||.||.
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

RNAERCARELA--HFPYVVVPRVH
||||.|.....  |.|...|||.|
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK5.AA ABC1 188-304 38 2.5e-48 164.78 Pfam 1-126 (126) Show / Hide 
Range on Protein: 188-304
Range on HMM: 1-126/126
Sequence Identity: 38% (49 aa)

EDFQALPHELFQEFDYQPIAAASLAQVHRAKLHD-GTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPS-----FGFSWVLQDLKGTLAQELDFENE
|.. . ..|.|||||..||||||.||||||.|.| |  ||||||. ....|.. || ........|.   |      | . |...... .|..|||...|
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

GRNAERCARELAHF---PYVVVPRVH
..|.||... ..|.   |.| ||.|.
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK5.AA ABC1-A 201-231 58 7.7e-14 44.46 In-house 1-31 (216) Show / Hide 
Range on Protein: 201-231
Range on HMM: 1-31/216
Sequence Identity: 58% (18 aa)

FDYQPIAAASLAQVHRAKLHDGTSVAVKVQY
|   | |.||  |||.| | ||. ||||.||
FEEMPFACASIGQVHQAVLKDGREVAVKIQY