Gene ANKRD3 (Human)

ANKRD3

Species: Human
Alias: DIK, ANKRD3, RIPK4, RIP4, PKK, ANKK2, MGC129992, MGC129993
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 21q22.3,

Classification

Group: TKL
Family: RIPK

Sequence

Name Sequence Type Origin Length Description Download
ANKRD3.kin_dom Protein Kinase Domain Sugen Kinome 264 None Fasta, JSON
ANKRD3.AA Protein Sugen Kinome 784 None Fasta, JSON
ANKRD3.NA RNA Sugen Kinome 3907 None Fasta, JSON

Protein domain

Protein domains of ANKRD3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ANKRD3.AA RIPK 28-283 46 7.29999999999e-160 537.38 In-house 1-290 (290) Show / Hide 
Range on Protein: 28-283
Range on HMM: 1-290/290
Sequence Identity: 46% (135 aa)

VGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVD----DRERMELLEEAKKMEMAKFRYILPVYGICREP--------VGLVMEYMETGSLEKLLASEP---
||.||||.|.|.||.||..|.|.||.|..|..    |.|||...||||.|.......|.|.||.|...        .|.||||||.|||...|....   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---LPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHD--------LSMDGLF--GTIAYLPPERIR--EKS
   .||.||.|.|||...||..||.| ||..|.||||.|||.|...||||.|||||.... ||||.        .||....  ||..|.|||..|  .|.
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

RL--FDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPR--ACSHLIRLMQRCWQGDPRVRPTFQEITSET
..  ...|.||||||||.|.|||||.|..|.|....||.....||||.|.||....|.  .|...|.||||||| ||..||.|||....|
PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase ANKRD3.AA TKL 28-283 26 3e-90 306.12 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-283
Range on HMM: 1-364/364
Sequence Identity: 26% (97 aa)

VGSGGFGQVYKVRHVHWK--------TWLAIKCSPSLHVDDRER-------------------------MELLEEAKKMEMAKFRYILPVYG--------
.||||||.||| ..  |         .. |.|  .| ..| ...                          .. ||.. | . .   |.. .|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-ICREP------VGLVMEYMETGS-LEKLLASEPLPWDLRFRIIHETAVGMNFLHCMA------PPLLHLDLKPANILLDAHYH--------------VK
 .| .|       ..||||.. || |. |.      |..|.|.....| |||.|| |       ||..| |||..|||.| ...              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ISDFGLAKCNGLSHSHDLSMDG----------------LFGTIAYLPPERIREK--------------SRLFDTKHDVYSFAIVIWGVLTQKKPFADEKN
|.||||....  | .   .| .                  ||.....|| .|..              .. ...|.|||||.||.| .|| ..|..|...
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

ILHI---------MVKVVKGHRPELPPVCRA------RPRACSHLIRLMQRCWQGDPRVRPTFQEITSET
. .|         |. ..||.||..||...        | .  ....|||.||. ||. ||.||||... 
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ANKRD3.AA MLK 78-283 30 5.9e-49 167.95 In-house 68-291 (291) Show / Hide 
Range on Protein: 78-283
Range on HMM: 68-291/291
Sequence Identity: 30% (71 aa)

FRYILPVYGICREP---VGLVMEYMETGSLEKLLASEP---------------LPWDLRFRIIHETAVGMNFLHCMAP-PLLHLDLKPANILLDA-----
. .| ..||.| .|   ...||||.| |||  .|....                . |. ... .  | ||..||.||| |. | |||. |||.|.     
HPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDM

-HYHVKISDFGLAKCNGLSHSHDLS-MDGLFGTIAYLPPERIRE-KSRLFDTKHDVYSFAIVIWGVLTQKKPFA-DEKNILHIMVKVVKGHRPELPPVCR
 | ..||.|||...     |... . | .  || |.  || |   ..  .. | ||.|...|.| .|| . |.. . ...  ..  ...| || .|. | 
HHGTLKICDFGTSRD---WHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCP

ARPRACSHLIRLMQRCWQGDPRVRPTFQEITSET
.      |. .||..||. ||. ||.|..| .. 
E------HWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase ANKRD3.AA TKL-Unique 25-283 28 2.6e-47 163.51 In-house 2-290 (290) Show / Hide 
Range on Protein: 25-283
Range on HMM: 2-290/290
Sequence Identity: 28% (86 aa)

WEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHV----DDRERMELLEEAKKMEMAK-FRYILPVYGICR----EPV--GLVMEYMETGSLEKLLA----
|.|.|.||.|||||.  .. ..  |||   ..|.      ... |. .| . |.. .    |.  .|.|      |    .||||.. ||| ..|.    
WNKIGEGGYGQVYKG--KWRGYPVAIK---QFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

-------SEPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAH-----YHVKISDFGLAKCNGLSHSHDLSMD------GLFGTIAYLPPE
       . .|.. .| ....  | ||..||   || .|.|||. |.|.| .     . .||.||||.| |  .    ...       .  |.. ...||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

RIREKSRLFDTKHDVYSFAIVIWGVLTQKK------PFADEKNI-LHIMVKVV-KGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSET
 .|    ....| |||||.|| |  .| |       |. .   . .  ||... .. ||..|. |  .      .  |.|.||  ||  ||.|.|| .. 
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKE------YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase ANKRD3.AA Dicty4 95-285 32 4.9e-45 148.25 In-house 80-277 (277) Show / Hide 
Range on Protein: 95-285
Range on HMM: 80-277/277
Sequence Identity: 32% (67 aa)

VMEYMETGSLEKLLAS--------EPLPWDLRFR---IIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFG
|.|||  |.|..|| .         .|.| |. |   .   .| ||| |||  |  .|.|||..|.| |... ||..||||..      .|   ...  |
VTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACG

TIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFA-DEKNILHIMVKVVK-GHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITS
| ..  ||  ....  .. | |||||.|| |  || . |..   ...  .   |.  . ||..|. | ..      ...|.|.||  || .||.|.||..
TPCWMAPEVMMHQP--YNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPS------WKHLIQWCWDHDPQHRPSFEEIIQ

E--TED
.   | 
RRILEH
Pkinase ANKRD3.AA Pkinase 22-279 22 1.6e-44 158.47 Pfam 1-287 (293) Show / Hide 
Range on Protein: 22-279
Range on HMM: 1-287/293
Sequence Identity: 22% (67 aa)

FTGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLE--EAKKMEMAKFRYILPVYGICR---EPVGLVMEYMETG----SLEKLLA---
..  .|.|||.||.||| .|.      |.|. .  | .. ......   |.. | . .  .|.  |....   ..  .||||.| |    .|  ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

SEPL--PWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHV----KISDFGLAKC-NGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDT
. ..  ...   ... ... |....| |    .| ||||.|||.| ..|.    ||.||||||. .   . ..  |... ||. |..|| || ...  ..
HGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

KHDVYSFAIVIWGVLTQKKPFADE-----KNILHIMVKVVK----GHRPELPPVC-----------RARPRACSHLIRLMQRCWQGDPRVRPTFQEI
| |..|. .... .|. . || ..      . ....... .     ..|.. ..            .  ... . .. .. .|.. ||  |||...|
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI
Kinase ANKRD3.AA LRRK 80-285 29 8.8e-41 141.8 In-house 118-351 (351) Show / Hide 
Range on Protein: 80-285
Range on HMM: 118-351/351
Sequence Identity: 29% (70 aa)

YILPVYGICREPVGLVMEYMETGSLEKLLA---SEP-------LPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILL---D---------AHYHV
.|.. .|.| .|  .||||.  |.| ..|    . .       ..| |. .|  . | ||..||   ||..| |||. ||||   .         ||...
NIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCA

KISDFGLAKCNGLSHSHDLS--MDGLFGTIAYLPPERIREK-SRLFDTKHDVYSFAIVIWGVLTQKKPFADEKN-------ILHIMVKVVKGHRPELPPV
||.|||.     .  . ...    |. |.. .. || .|.     ...| |.|||....|  || . .. || .       . .|  |. .|.|| .|. 
KIADFGISR---MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQH

-CRA--RPRACSHLIRLMQRCWQGDPRVRPTFQEITSETED
 |.    .. .. ||   | |||.||. ||.|..|..  ..
YCPPCQPWHMYQDLI---QHCWQHDPKKRPHFSQIVKRLSQ
S_TKc ANKRD3.AA S_TKc 22-281 23 8.4e-39 136.14 SMART 1-220 (231) Show / Hide 
Range on Protein: 22-281
Range on HMM: 1-220/231
Sequence Identity: 23% (63 aa)

FTGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICR-EPVGLVMEYMET--GSLEKLLASEP------
..  .|.|.|.||.|||.||.. .   |||. .           .. | . ... .  .|   |.... . . .||||...  |.| ... . .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDT-KHDVYSFA
 .|     ....... .....| .    .| ||||.|||||   |.||.|||||.            . . ||  |..|| .      ... | |..|. 
PFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCG

IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITS
....  |. . ||      .. | |...                 . .. ....|.| ||. |||  |.  
CILYEMLCGYPPFP----QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase ANKRD3.AA TK 22-283 16 2.1e-37 122.39 In-house 1-486 (486) Show / Hide 
Range on Protein: 22-283
Range on HMM: 1-486/486
Sequence Identity: 16% (83 aa)

FTGWEKVGSGGFG---QVYKVRHV---HWK----------------------TWLAIKCSPSLH-VDDRERME--------------LLEEAKKME--MA
 |  .| |.| ||   .||| .      |.                      |  |.|.  . .  ...|...              ..||.|.|   . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KFRYILPVYGIC--------------REPVGLVMEYMETGS----LEKLLASEP----------------------------------------------
.   |.  ||.|              .||. .|||||. |.    | . | . .                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LPWDLRFRIIHETAVGMNFLHCMAP----PLLHLDLKPANILLDAHYH-----------VKISDFGLA-
                               |.   .  . .  | || .|| .       . | ||   |.|.. ...           .||.||||. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----KCNGLSHSHDLSMDGLFGT-------------------------IAYLPPERIREK-------SRLFDTKHDVYSFAIVIWGVLTQK-KPFADEK
      .  . ...|   ..  ||                         | ...|| ....        . | || ||.|| ...| ..|   .|.. . 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

NI---------LHIMVKVVKG--------------HRPELPPVCRA----RPRACS-----HLI-RLMQRCWQGDPRVRPTFQEITSET
.            .| ....|              .|.. || |      |  .        .. .|||.||. ||. ||||... .. 
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase ANKRD3.AA DRK 95-285 35 2e-33 110.58 In-house 75-258 (258) Show / Hide 
Range on Protein: 95-285
Range on HMM: 75-258/258
Sequence Identity: 35% (69 aa)

VMEYMETGSLEKLLASE--PLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPER
.||||  ||| . |  |   . | |. ..    | ||..|||  |  .| |||  | | | |. ||..||||.       .|   |    ||     || 
CMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAM-TMCGTPCWTAPEV

IREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVK-GHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETED
 |.    .  | |||||||| | ..| . |..  .. . .   | . | ||  |. | .        |.||..||  ||  ||..||.    | 
LRNQR--YTEKADVYSFAIVLWECVTRQDPYFG-MPTFQVVFSVGRHGMRPPMPQWCPPK------YIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase ANKRD3.AA TKL-ciliate1 94-279 28 8.8e-31 102.59 In-house 76-275 (279) Show / Hide 
Range on Protein: 94-279
Range on HMM: 76-275/279
Sequence Identity: 28% (57 aa)

LVMEYMETGSLEKLLA---S--EPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGL------F
..||. . |..  ..    |   ...|. | |.. . | || .||   .|| | |||  |||.|  |  || .|.  | .        | . .       
IIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQRN

GTIAYLPPERIR---EKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGH-RPELPPVCRARPRACS-HLIRLMQRCWQGDPRVRPTFQ
.|  .  || ..      .   .| |.|...|| .     |.||    . . ||. .  .  || | |     .  |.  .. ||.|||  .|  || |.
TTFHWMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGP--QFIHFDCPQNFHNLMMRCWCQNPNKRPNFN

EI
||
EI
Kinase ANKRD3.AA TyrKc 22-286 26 5.1e-30 106.97 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-286
Range on HMM: 1-280/280
Sequence Identity: 26% (80 aa)

FTGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMA--KFRYILPVYGICR---------EPVGLVMEYMETGSLEKLLAS
 |  .| |.| ||.||| .     .  |.|.  . .     |.....||. | .   .   |.  ||.|.         ||. .|||||. |.| . | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

EP--LPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLS------HSHDLSMD--GLF--GTIAYLPPERIREKSR
    |...    . .  | ||..|| .  .. | ||   |.|... ..||||||||..  .        ..   ..   |      |  ..|| |  . .
HRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYG

LFDTKHDVYSFAIVIWGVLTQ-KKPFADE----KNILHIMVKVVKGHRPELPPV-----CRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDL
 | || ||.|| ...| ..|  ..|  ..    ..  ... .| .|.|.. ||          ... . . ..|..||. ||  ||||.||    |..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase ANKRD3.AA Pkinase_Tyr 26-286 29 1.3e-21 73.83 Pfam 5-270 (270) Show / Hide 
Range on Protein: 26-286
Range on HMM: 5-270/270
Sequence Identity: 29% (83 aa)

EKVGSGGFGQVYKVRHV----HWKTWLAIKCSPSLHVDDRE--RMELLEEAKKMEMA-KFRYILPVYGICR---EP--VGLVMEYMETGSLEKLLASE--
.| |.| ||.||| .        |.  |.|. .  . ....  | ....||| |    .   |.  ||.|    ||  . .|||||. |.| . | .   
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRE

---PLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHD-LSMDGLFGTIAYLPPERIREKSRLFDTKHDVY
   ||.      . .. | ||..|. .   . | ||   |.|..   .|||.|||||.    . .    . .|    |  ..|| |...   | || ||.
DKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGK--FTTKSDVW

SFAIVIWGVLT-QKKP-FADEKNILHIMVKV-VKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDL
|| ...| ..|  ..| ... .|   .. ..  .|.| . |. |      .  . .||..||. ||  ||||.||    |.|
SFGVLMWEIFTYGEQPTYPGMSNEE-VYEYIYEDGYRMPCPENC------PDEIYDLMKQCWHYDPEDRPTFSEI---HEQL
Kinase ANKRD3.AA TAK1 201-282 28 4e-18 57.72 In-house 203-284 (284) Show / Hide 
Range on Protein: 201-282
Range on HMM: 203-284/284
Sequence Identity: 28% (24 aa)

DTKHDVYSFAIVIWGVLTQKKPFADEKN---ILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSE
. | |.||..|. | |.. |.|. .  |   .  || .. .|   ..||  . |  .   .  .|..||. .|  ||. ||.   
NMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNG---NRPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY
Kinase ANKRD3.AA TAK1 23-165 28 3.2e-14 44.35 In-house 2-153 (284) Show / Hide 
Range on Protein: 23-165
Range on HMM: 2-153/284
Sequence Identity: 28% (44 aa)

TGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSL--HVDDRERMELLEEAKKMEMAKFRYILPVYGI--CRE-PVGLVMEYMETGSLEKLLAS-EPLP--
.  ..|| | .| |.|   .  ..  |.|    .       |. .  .| .    ..   |  .||.  | . ...||||||. |||  .| . .| .  
QNEHFVGKGTYGVVCKA--KWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVDHPNIIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKPKWEY

-WDLRFRIIHETAVGMNFLHCMA-PPLLHLDLKPANILLDAHYHV-KISDFGLA
  .  ..  |  | | ..|| |   |. | |.||.| || ... . || |||..
THAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTF
Kinase ANKRD3.AA MLK 22-40 47 0.006242 6.16 In-house 1-19 (291) Show / Hide 
Range on Protein: 22-40
Range on HMM: 1-19/291
Sequence Identity: 47% (9 aa)

FTGWEKVGSGGFGQVYKVR
..  |..|||.||.|.| |
IQFHEWIGSGSFGKVWKGR
Kinase ANKRD3.AA LRRK 22-38 44 0.027287 3.89 In-house 1-18 (351) Show / Hide 
Range on Protein: 22-38
Range on HMM: 1-18/351
Sequence Identity: 44% (8 aa)

FTGWEKVGSGGFG-QVYK
.   |..|.||||  ||.
LKIEEQIGRGGFGTFVYR
Kinase ANKRD3.AA Dicty4 22-38 41 0.175182 0.91 In-house 1-17 (277) Show / Hide 
Range on Protein: 22-38
Range on HMM: 1-17/277
Sequence Identity: 41% (7 aa)

FTGWEKVGSGGFGQVYK
 .  .. |.|.||.|||
INIEQRIGKGSFGEVYK
Ank ANKRD3.AA Ank 603-635 45 1e-09 39.28 Pfam 1-33 (33) Show / Hide 
Range on Protein: 603-635
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

DGRTPLHLAAQRGHYRVARILIDLCSDVNVCSL
||.||||||...||..|.. |..   |||.   
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 536-568 42 4.4e-09 37.03 Pfam 1-33 (33) Show / Hide 
Range on Protein: 536-568
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

EGRTPMHVACQHGQENIVRILLRRGVDVSLQGK
.|.|| |.||..|....|. || .| || .| .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 503-535 36 7.2e-08 32.64 Pfam 1-33 (33) Show / Hide 
Range on Protein: 503-535
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

DQWTALHFAAQNGDESSTRLLLEKNASVNEVDF
| .|.|| |...|...  ..||...|.|| .| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 470-502 42 2.8e-07 30.54 Pfam 1-33 (33) Show / Hide 
Range on Protein: 470-502
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

RGSTPLHMAVERRVRGVVELLLARKISVNAKDE
 | ||||.|...    ||..|| .  .|||.| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 437-469 36 2e-06 27.8 Pfam 1-33 (33) Show / Hide 
Range on Protein: 437-469
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

SGASLLHLAVEAGQEECAKWLLLNNANPNLSNR
 | . ||||.. |..|..|.|| ..|..|. ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 569-602 44 5e-06 26.07 Pfam 1-33 (33) Show / Hide 
Range on Protein: 569-602
Range on HMM: 1-33/33
Sequence Identity: 44% (15 aa)

DAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL
| . |||.|.  ||. .||.| .  | .||||. 
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank ANKRD3.AA Ank 669-701 51 1.1e-09 39.25 Pfam 1-33 (33) Show / Hide 
Range on Protein: 669-701
Range on HMM: 1-33/33
Sequence Identity: 51% (17 aa)

DGYTALHLAARNGHLATVKLLVEEKADVLARGP
||.|.||||.|.||.  ||.|..  ||| |.  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 638-668 41 1.9e-05 23.9 Pfam 3-33 (33) Show / Hide 
Range on Protein: 638-668
Range on HMM: 3-33/33
Sequence Identity: 41% (13 aa)

QTPLHVAAETGHTSTARLLLHRGAGKEAMTS
.||||.|.. |||. ...|| .||   | . 
FTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 702-732 45 4e-05 22.75 Pfam 1-33 (33) Show / Hide 
Range on Protein: 702-732
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

LNQTALHLAAAHGHSEVVEELVS--ADVIDLFD
  .|.||||. .|| |||..|..  |||    |
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKRD3.AA Ank 734-766 42 1.9e-07 31.08 Pfam 1-33 (33) Show / Hide 
Range on Protein: 734-766
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

QGLSALHLAAQGRHAQTVETLLRHGAHINLQSL
 | ..||||..  |.. |. || ||| .|.|  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD