Gene BRDT (Human)

BRDT

Species: Human
Alias: BRDT, BRD6
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 1p21,

Classification

Group: Atypical
Family: BRD

Sequence

Name Sequence Type Origin Length Description Download
BRDT.AA Protein Sugen Kinome 947 None Fasta, JSON
BRDT.NA RNA Sugen Kinome 3156 None Fasta, JSON

Protein domain

Protein domains of BRDT.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BROMO BRDT.AA BROMO 25-135 41 8.5e-46 159.38 SMART 1-118 (118) Show / Hide 
Range on Protein: 25-135
Range on HMM: 1-118/118
Sequence Identity: 41% (49 aa)

NGRLTNQLQYLQKVVLKDLWKH--------SFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIV
  .  ...| | |.|.. . .|         ..|||..|||...| .|||| ||||||||.||||.||| .|  . | ..||. ||.||. ||.|. .. 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

LMAQALEKLFMQKLSQMPQ
 ||. |.|.|..|. ..|.
KMAKKLQKFFEEKWREFPP
Bromodomain BRDT.AA Bromodomain 36-121 35 5.5e-31 103.46 Pfam 1-89 (89) Show / Hide 
Range on Protein: 36-121
Range on HMM: 1-89/89
Sequence Identity: 35% (32 aa)

QKVVLK--DLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYA-KASECIEDFNTMFSNCYLYNKPGDDIVLMAQA
 . ...  ....| ...||..||| .. ..|||| |||.||||.||...|.|..|     | ..|.. |..||. ||.|...|  .|. 
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO BRDT.AA BROMO 269-378 42 5.2e-46 160.09 SMART 1-118 (118) Show / Hide 
Range on Protein: 269-378
Range on HMM: 1-118/118
Sequence Identity: 42% (51 aa)

VTEQLRHCSEILKEMLAKKHFS---------YAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVV
  . .. |.|.|||....|| .         |||||..|||.. |....|||..||||||.|||.|..| .|...  |..|..||| ||..||.||.|| 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

TMARMLQDVFETHFSKIPI
 ||..||..|| .. ..| 
KMAKKLQKFFEEKWREFPP
Bromodomain BRDT.AA Bromodomain 276-364 34 1.6e-28 95.44 Pfam 1-89 (89) Show / Hide 
Range on Protein: 276-364
Range on HMM: 1-89/89
Sequence Identity: 34% (32 aa)

CSEILK--EMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYK-DAYKFAADVRLMFMNCYKYNPPDHEVVTMARM
|..|..  ... ..    ..||  |||..  .. .|||..|.|||| ||..|..|..|.   . | .|..||. ||..||.||...  .|| 
CDQIMDMKYIMEHP---ICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK