CaMK2d

Species: Human
Alias: CaMK2d, CAMK2D, MGC44911, CAMKD
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 4q25-q26,

Classification

Group: CAMK
Family: CAMK2

Sequence

Name Sequence Type Origin Length Description Download
CaMK2d.kin_dom Protein Kinase Domain Sugen Kinome 259 None Fasta, JSON
CaMK2d.AA Protein Sugen Kinome 533 None Fasta, JSON
CaMK2d.NA RNA Sugen Kinome 5974 None Fasta, JSON

Protein domain

Protein domains of CaMK2d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMK2d.AA CAMK2 14-272 94 4.7e-224 750.62 In-house 1-259 (259) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-259/259
Sequence Identity: 94% (246 aa)

YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADA
||||||||||||||||||.|. |||||||||||||||||||||||||||||||.|||||||||||||.||||||||||||||||||||||||||||||||
YQLFEELGKGAFSVVRRCVKKCTGQEYAAKIINTKKLSARDHQKLEREARICRKLKHPNIVRLHDSIQEEGFHYLVFDLVTGGELFEDIVAREYYSEADA

SHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPP
||||||||||||||| ||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||
SHCIQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP

FWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI
|||||||||||||||||||.|||||||||||||.|||.||||||.|||||.||||||||
FWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI

Kinase CaMK2d.AA CAMK1 14-272 44 2.8e-153 448.97 In-house 1-276 (276) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-276/276
Sequence Identity: 44% (123 aa)

YQLFEELGKGAFSVVRRCMKIPT---GQEYAAKIIN-TKKLSARDH---QKLEREARICRL---LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIV
|....|.|.||||.|..| .. |   |..|| |.|.  | ..  |    ..||.|  | .    ..||||. ...   .. . ||| .||||||||. ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVK--LADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRK---DPYGKPVDMW
 ...|.| ||.|...|||. |...| .|||||||||||||...|. .. .|  .|||||.  . .|    .   |||||  ||||     .||.|..|||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

ACGVILYILLVGYPPFWDED-QHRLYQQIKAGAYDFPSPEWDTVTPE-AKDLINKMLTINPAKRITASEALKHPWI
 .|||.||||.|||||.||. .. |...|| . |.||||.|| .  . |||.|..||. .| ||.|....|.||||
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase CaMK2d.AA CAMK 19-272 26 4.4e-135 438.03 In-house 1-425 (425) Show / Hide
Range on Protein: 19-272
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)

ELGKGAFSVVRRCMKIPTG------------QEYAAKIINTKKLS--------------------------ARDHQKLEREARICRL-------LKHPNI
.||.|.|..|..|. . |.            |..|.|||..|||.                          ..| ....|| .|...       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLHDSISEEGF-------------------HYLVF---DLVTGGEL----FEDIVAREY---------------YSEADASHCIQQILESVNHCHLNGI
..|.. .  . .                    |.|.   ....||||    |. ||....               ..|..|.....||.. |..|| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLLASKSKG--------------AAVKLADFGLAIEVQGDQ-----------------------QAWFGFAGTPGYLS-PEVLRK------
|||||||||.|| .....              . .|..|||.|.......                       |    | |||.| . ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DPYGKPVDMWACGVILYILLVGYPPFWDE-------------DQHRLYQQIKAGAYDFPSPE------------WDTVTPE--------AKD
        ..||...|||.|||||||.|.|||||...             ....|...|..| ||||.|.            || .. |        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINKMLTINPAKRITASEALKHPWI
||.|||. .| ||.|....|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase CaMK2d.AA RAD53 14-272 35 1.2e-113 340.03 In-house 1-305 (305) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-305/305
Sequence Identity: 35% (110 aa)

YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS---ARD---HQKLEREARICRLLKHPNIVRLHDSISE-EGFHYLVFDLVTGGELFEDIVARE
| . .|||.|.|..|... .  |.| .| |||..||..    ..      ...|..| . |.||.|.|..|.. . .   |.|  |.||||||..||...
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

Y----YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA---------------AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR
.    ..|...     |....|.  | |||.|||||||| |.......                ..|..||||.  ..|...    . ||| |. |||..
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-KFVGEGSFMKTMCGTPQYVAPEVIT

KD---------------PYGKPVDMWACGVILYILLVGYPPFWDE-DQ----HRLYQQIKA-GAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEA
.                 |.| ||.|  |.||||.| ||||| |. .|      |..|||  | | ||.|.|| .. ||||||..||...| ||.|. ||
SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LKHPWI
| |||.
LNHPWM

Kinase CaMK2d.AA CDPK 14-272 40 2.5e-112 345.79 In-house 1-271 (271) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-271/271
Sequence Identity: 40% (111 aa)

YQLFEELGKGAFSVVRRCMKI-PTGQEY-AAKIINTKKLSARDH-QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFD--LVTGGELFEDIVAREYY
|.. ..||||.|..||.. .   |.||  | |||. ....  .  |.. .|  | . | ||||...      | ..|.|.   ..||||||. |... ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA----AVKLADFGLAIEVQGD----QQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWAC
.| .|.  ..|||  ||.|| |.||||||||||.|. ||....     .|. |.|.. . ...     .    ..||| |..||||.|  | . .| | |
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI
||||||||.|||||. . .   ....| | |.|  |||| .. ||||||.|||. .| ||..|..||.|||.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF

Kinase CaMK2d.AA S_TKc 14-272 36 6.2e-112 379.09 SMART 1-231 (231) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-231/231
Sequence Identity: 36% (101 aa)

YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG--GELFEDIVAREY----
|.. ...|||||..|..| .. ||...| |||.         ....|| .|..  .|||||.|.|.. . .. |.|.... |  |.||. |. | .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK-PVDMWACGVIL
  ..| .| . ..||.. ...|| .||.||||||||.|| .      .|..||||| ..         | ||| |..||||   .||| ..|.|.||.||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALK-------HPWI
|..|.|||||.  ........|.              .|||||.|.|.|. .|.||.|| |||.       |||.
YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CaMK2d.AA DCAMKL 14-272 39 1.3e-103 323.31 In-house 1-279 (279) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-279/279
Sequence Identity: 39% (110 aa)

YQLFEELGKGAFSVVRRCMKIPTG-QEYAAKI-----------------INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG
||.    |.| |.||  | .  || ..|| ||                 |. .|.    |   . | .| ...|||.|..|... . |   |||. .|.|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM-IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG

GELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLAS-KSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKP
| ||. |.    ..| ||.  . .. .  .. |  .|||||.||||||.    ..   .||.||||| .|.||    .   ||| |  ||.|..  ||  
GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

VDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWI
||.|| ||||||||.|.|||  .  || .|  || .|...||.|.|| ..  |||||..||  .| || ||.. ..|||.
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV

Kinase CaMK2d.AA Pkinase 14-272 34 4.1e-101 347.02 Pfam 1-293 (293) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER--EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG----ELFEDIV--AR
|.. . .|.|.|..|..|... ||...| |||. .. .   .| . |  |..| . |.|||||||.|.  ...  |.|.... ||    .||. |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EYY--SEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLA-SKSKGAAVKLADFGLAIEV-QGDQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDMWAC
  .  || .. ... |||. ...|| .||.||||||||.|.      .| ||..|||||  .    ..   .|.|||.|..|||.|   .||..||||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYILLVGYPPFWDE------DQHRLYQQIKAGAYDFPSPEWDTVT-----------------PEAKDLINKMLTINPAKRITASEALKHPWI
|.|||..| |.|||...      ||  ....|. . ..|..|.|...                  .|.||.|...|. .|.||.|| ..|.|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase CaMK2d.AA CAMKL 14-272 34 8.6e-96 306.18 In-house 1-297 (297) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-297/297
Sequence Identity: 34% (106 aa)

YQLFEELGKGAFSVVRRCMK-IPTGQEYAAKIINTKKLS--------------ARDHQKLEREARICRLLK---HPNIVRLHDSISEEGF------HYLV
|.. ..||||.|..|. ..  . ||...| |||. ||..               .|  ...||..| ..|.   ||||..|.. |  . .       |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

FDLVTGGE--LFEDIVAREY----YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIE---V-QGDQQAWFGFAGTPG
  .. |||  ||. ||....     .| .| .  .||.. ||.|| .||||||.||||.|| .. .   .|..|||....   .  |. |    | |.| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YLSPEVLRK--DPYG-KPVDMWACGVILYILLVGYPPFWDE--------DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALK
| .||.. .  .||  ..||.|.|||||| ...|| || |.        .. .|| .|. | | .|   |  |  ...||| |||. || ||.|. . ..
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWI
||| 
HPWM

Kinase CaMK2d.AA CAMK-Unique 14-272 25 2e-93 308.8 In-house 1-363 (363) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-363/363
Sequence Identity: 25% (91 aa)

YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS-ARDHQ-----------------KLEREARICRLLKHPNIVRLHDS----ISEEG-------
| . . .|.|.|..|..|| . || ..| |... .. .  . .|                 ||.||..| ....||||..| |        .        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------FHYLVFDLVTGGELFEDIVA--------------------REYYSE--ADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSK-----
          |.| ....||.||. |..                    . ..||  .|..  .|..|. |.. | ..|||||||.||... .  |     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------GAAVKLADFGLAIEVQGDQQA--WFGFAGTPGYLSP--------------EVLRKDPYGKPV----DMWACGVILYILLVGYPPFWDEDQH-
           .||.||||. .... .       . ||| |..|              ||.  ..|. ..    | |..|||.|..|.|.|||  |.   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------RLYQQIKAGAY-DFPSPEWDT---VTPEAKDLINKMLTINPAKRITASEALKHPWI
       .... |..| | .|... |.    ...||||.. . .|. |..|..|.|.|.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase CaMK2d.AA RSK 16-272 33 5.3e-89 302.0 In-house 1-278 (278) Show / Hide
Range on Protein: 16-272
Range on HMM: 1-278/278
Sequence Identity: 33% (93 aa)

LFEE--LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDH-QKLER-EARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY---
| .   .|.|.....|.|    |||.|| |... .|. .|.  ..  . | .|  . . ||.||.||..  .||  ||. ... |||||. .  ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKG-AAVKLADFGLAIE-VQGDQQAWFGFAGTPGYLSPEVLR---KDP-YGKPVDMWACG
 || .|.  . .|   | | |  ||.|||||||| |....| . . .|| |||.. . .  . |    | .|  |. ||.|.   ..  ..| .| |  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VILYILLVGYPPFWD---EDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRIT-----ASEALKHPWI
|..| .|.|.|||     .... . ..|. | .....|.|.....||||||.|||. .|.||..     |.| ..|||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase CaMK2d.AA Ciliate-E2 14-272 25 7.7e-87 294.8 In-house 1-365 (365) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

YQLFEELGKGAFSVVRRCMKIPTG-----------------------QEYAAKIINTKKLSARDH-QKLEREAR----------ICRLLKHPNIVRLHDS
| . . .|.|.|..|..| .. ..                       ..|| ||.. ... .    ... || .          |...|.||||......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IS--EEGFHYLVFDLVTGGELFEDIV------------AREYYSEADASHCIQQILE---------------SVNHCHLNG-IVHRDLKPENLLLASKSK
     .   |||.... ||.||. |             . .|..|  ... ..|||.                ....| .. |.|||.||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

GAAVKLADFGLAIEVQGD-------------------------------QQAWFGFAGTPGYLSPEVLRKDP---------YGKPVDMWACGVILYILLV
   .|..||||. ... |                               |.  . ..|||||..||.|.. .         |.. .|.|..|||||..| 
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GYPPFWDEDQHRLYQQIKAGAYDFPSPE--------------WDTVTPEAKDLINK----MLTINPAKRIT-ASEALKHPWI
|.|||        .|||| . .|||.||              |. ...|.||||.|    ||  .| |||| ....|.|||.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase CaMK2d.AA TyrKc 14-272 21 4.6e-14 4.69 SMART 1-280 (280) Show / Hide
Range on Protein: 14-272
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL--KHPNIVRLHDSISEE-------GFHYLVFDLVTGGELFEDIVA
 .| ..|| ||| .|.... .   .. | | ..  .     .. . ||||| . |  .|||||||.  ....       . ...|. .. .| | . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

REY-YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGD-----QQAWFGFA---GTPG-----YLSPEVLRKDP
..   . .|  .   || .  .. | ....||||   | |....     || .||||. ..  |      .     .   |. .      ..||....  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGKPVDMWACGVILY-ILLVGYPPFWD-----EDQHRLYQQIKAGAYDFPSPE-----WDTVTPEAKDLINKMLTINPAKRITASEALKHPWI
.    | |. || .. |.  | .| ..      .  ......|.| .  . |.       . ..|  ... .    .|..| | ||   |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase CaMK2d.AA Pkinase_Tyr 14-98 26 4.8e-07 24.48 Pfam 1-94 (270) Show / Hide
Range on Protein: 14-98
Range on HMM: 1-94/270
Sequence Identity: 26% (25 aa)

YQLFEELGKGAFSVVRRCMKI----PTGQEYAAKIINTKKLSARD--HQKLEREARICRLL-KHPNIVRLHDSIS-EEGF--HYLVFDLVTGGEL
 .. ..||.||| .|...        |... | |..   . . ..  .... |||.| . | .|||||||.  .. ...   .|.|. .. .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

Kinase CaMK2d.AA Pkinase_Tyr 128-167 35 0.175891 5.64 Pfam 128-164 (270) Show / Hide
Range on Protein: 128-167
Range on HMM: 128-164/270
Sequence Identity: 35% (14 aa)

HLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGD
. ....||||   | |...   .  || .|||||  .. |
ESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYND

CaMKII_AD CaMK2d.AA CaMKII_AD 380-507 67 9.6e-94 322.54 Pfam 1-128 (128) Show / Hide
Range on Protein: 380-507
Range on HMM: 1-128/128
Sequence Identity: 67% (87 aa)

RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPK
.||||.||||..||||..||...|||.|.|..|.||.||.|||||||.|||||||....|..|..||..||||||..||||||.||.||||||| .||..
EKQEIWKVTERWIEAIYCGDWHTYTKLCHPDMTCFEWEACGNLVEGMEFHRFYFEMHWTKRCKAVHTTMLNPHVHMYGDDAACCAYVRLTQYMDKNGMAH

TMQSEETRVWHRRDGKWQNVHFHRSGSP
|.|||||||||.||||||.||.|||..|
TRQSEETRVWHKRDGKWQCVHHHRSAMP