Gene CaMK4 (Human)

CaMK4

Species: Human
Alias: CaMK-GR, MGC36771, CaMK4, CAMK4
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 5q22.1,

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
CaMK4.AA Protein Sugen Kinome 473 None Fasta, JSON
CaMK4.kin_dom Protein Kinase Domain Sugen Kinome 255 None Fasta, JSON
CaMK4.NA RNA Sugen Kinome 2168 None Fasta, JSON

Protein domain

Protein domains of CaMK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMK4.AA CAMK1 46-300 52 1.1e-200 589.13 In-house 1-276 (276) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-276/276
Sequence Identity: 52% (145 aa)

FEVESELGRGATSIVYRCKQKGT---QKPYALKVLK-KTVDKK-------IVRTEIGVLL---RLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIV
.|. .|.|||| |.||.|..| |   .|.||.|... |.. ||        ...||...    ...||||||..|..|..... ||.|||||||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

EKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLK--IADFGLSKIVEHQV-LMKTVCGTPGYCAPEILRG---CAYGPEVDMW
|||.|.|.||.. .||||.|| |.|..||||||||||||||... .|...|  |||||||||..|.. ||||.||||||.|||.| .   ..|. ..|||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLN-AKDLVRKLIVLDPKKRLTTFQALQHPWV
|.|.||||||||..|||||..|...|. |..||| |.|||||..|   |||........|||||.|  |.|.|||.
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CaMK4.AA CAMK 51-300 28 2.3e-133 432.42 In-house 1-425 (425) Show / Hide 
Range on Protein: 51-300
Range on HMM: 1-425/425
Sequence Identity: 28% (119 aa)

ELGRGATSIVYRCKQKGTQ------------KPYALKVLKK------------------------------TVDKKIVRTEIGVLLRLS-------HPNI
.||||. ..|..|..| |.            . .| |...|                               .|.| || || .. .|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLKEIFET-------------------PTEISLVL---ELVTGGEL----FDRIVEK---------------GYYSERDAADAVKQILEAVAYLHENGI
||| |..|.                   .... .|.   |...||||    ||.|||.               |...||.|.  ..||..||.|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLYATPAPD--------------APLKIADFGLSKIVEH------------------------QVLMKTVCGTPGYCA-PEILRG------
|||||||||.|. .  .|              ...||.|||.......                          .|||.||||.|.| ||.|.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------CAYGPEVDMWSVGIITYILLCGFEPFYDER------------GDQFMFRRILNCEYYFISPW------------WDEVSLN--------AKD
          |||..||||.|.|.||.|||. |||..              |. .|..|....|.|..|.            ||..| .        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVRKLIVLDPKKRLTTFQALQHPWV
|.||. . ||.||.|  |.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMK4.AA RAD53 46-300 36 3.6e-130 390.14 In-house 1-305 (305) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-305/305
Sequence Identity: 36% (112 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKK--------TV--DKKIVRTEIGVLLRLSHPNIIKLKEIFETP-TEISLVLELVTGGELFDRIVEKG
. .  |||.|. ..|.... | | . .| | ..|        ..  ... |..|. .| .|.||.||....||.|| .  ..||||.||||||..||  .
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

Y----YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDA---------------PLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILR-
.    ..| .. .  .|...|| |||.|||.|||||||| |..... .                 .||.||||||.|. . .||| |||| |.|||... 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

-GC-------------AYGPEVDMWSVGIITYILLCGFEPFYDERGD----QFMFRRILN-CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQAL
 |              .|...||.|| | |.||.|||. || |....      .|  |.|   | |..| ||..| .||||.......||.||.|. .||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

QHPWV
.||| 
NHPWM
Kinase CaMK4.AA Pkinase 46-300 37 6.30000000001e-117 399.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-293/293
Sequence Identity: 37% (112 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVR------TEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG----ELFDRIV--EK
..... .|.|. . ||.|. |||.| .|.|..||  .|. ..      .|| ...||.||||..|...||....| .|.|.. ||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GYY--SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYA-TPAPDAPLKIADFGLSKI--VEHQVLMKTVCGTPGYCAPEILR-GCAYGPEVDMWSV
| .  ||... . ..|||....|.|..||.||||||||.|.  .. .||..||.||||.|     ... |.|.||||.|.|||..| |  |||.|||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIITYILLCGFEPFYDE-----RGDQFMFRRILNCEYYFISPWWDEVS-----------------LNAKDLVRKLIVLDPKKRLTTFQALQHPWV
|.| |..|||  ||...     . ...|..||. ... | .|||...|                  ..||...... .|||||.|  |.|||||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CaMK4.AA DCAMKL 46-300 38 3.8e-108 337.62 In-house 1-279 (279) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-279/279
Sequence Identity: 38% (108 aa)

FEVESELGRGATSIVYRCKQKGTQ-KPYALKV-----------------LKKTVDK---KIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG
...    | | ...|. |... |. . ||.|.                  .|   |   ...  |. .. ...||.||.| | ..|.|.. ||.|.|.||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYAT-PAPDAPLKIADFGLSKIVEH-QVLMKTVCGTPGYCAPEILRGCAYGPEV
 ||| |.| . ..|||||  . .. .|  |||| .|||||.||||||    .     || .|||| ..|.    .. |||||| |.|||||.   || .|
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCKV

DMWSVGIITYILLCGFEPFYDE-RGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV
|.|..|.|.||||||| ||  . .  .  |  |. ... | .| ||..|. ||||.... . ||.|| |  | .|||||
DIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CaMK4.AA S_TKc 46-300 36 4.8e-108 366.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-231/231
Sequence Identity: 36% (100 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTG--GELFDRIVEKGY------YS
.|.  ..|.|| . ||.|. |.|.. .|.|..|     . .| || .| .  ||||.||...|.. ... .|.|.. |  |.|||.|...|.      ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

ERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLC
| .|.  ..||..|..|.|..||.||||||||.|  .      .||.||||....      .|.|||| |.|||.|    ||. ..|.||.|.| |..||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQ-------HPWV
|  ||.    .| ||..|.              |  |||..||. . ||.||.|  .|||       |||.
GYPPFP---QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMK4.AA CDPK 46-300 42 4.5e-105 323.18 In-house 1-271 (271) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-271/271
Sequence Identity: 42% (115 aa)

FEVESELGRGATSIVYRCKQK-GTQKPY-ALKVLKKT-VDKKI----VRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLE--LVTGGELFDRIVEKGYY
.  ...||.|. . |...|.| .|.    | |. .|  | .|     .  || .|  | ||||||. | ..    . .|.|  ..|||||||.|.|||..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDA----PLKIADFGLSKIVEHQ-----VLMKTVCGTPGYCAPEILRGCAYGPEVDMWSV
.|..||. ..||| ||.| |.|.||||||||||.|. .  .|.    ..|. |.|.||. ...       |.. |||| | |||.|..  |  ..| || 
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV
|.| ||||||  ||| .  ||  .  . ...| |  | ||..| .||||.||... |||||..  |||||||.
GVILYILLCGYPPFYGKN-DQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CaMK4.AA PSK 46-300 41 1.3e-99 319.04 In-house 1-258 (258) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-258/258
Sequence Identity: 41% (108 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-VDKK-IVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAAD
...    |.|  | | |  .. |..||| |.. .   . . .   |  .| |..||.||.| |.|||   . .|.|. ||||.||||| || ..||||  
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGREFCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDATR

AVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGL--SKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPF
. . .|... |||  .| |||||||||||. | ... . | ||||  ..      .|||.|||| | |||.|    |   |||| ||.|.|||. |. ||
VLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMPF

YDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV
 |.     ..|.||   | ..   | .||  ||| . || .... .|.|  ||..||||
DDDC-RTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase CaMK4.AA MAPKAPK 47-300 35 6e-96 297.54 In-house 1-292 (292) Show / Hide 
Range on Protein: 47-300
Range on HMM: 1-292/292
Sequence Identity: 35% (103 aa)

EVESE-LGRGATSIVYRCKQKGTQKPYALKVLKKT--VDKKIVRTEIGVLLRLS-HPNIIKLKEIFET----PTEISLVLELVTGGELFDRIVE--KGYY
 . .| || |.   | .|..| |.. ||.|.|...     . .| |   . . . ||||... ..||      .   ||.|.  |||||..| .  ....
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHF

SERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKI-------VEH--QVLMKTVCGTPGYCAPEILRGCA----YGPEVD
.|| |.  .|.| .||..||. .| ||||||||.|. ......|.|. |||. |         .   .. ..| |.|| |.|||..        |    |
TEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKSCD

MWSVGIITYILLCGFEPFYDERG------D---------QFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV
||| | | ||.|||. ||| . |      |         . ||.|| . .| | .. |...|  ||||.||| . ||..|||. | ..|||.
MWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase CaMK4.AA CAMKL 46-300 34 1.8e-91 292.2 In-house 1-297 (297) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-297/297
Sequence Identity: 34% (104 aa)

FEVESELGRGATSIVYRCKQ-KGTQKPYALKVLKKTVDKKI-----------------VRTEIGVLLRLS---HPNIIKLKEIFETPTE------ISLVL
.... .||.|. . |  ..  . |.. .| |...|   ...                 .| ||  . .|.   ||||||| |..|||.       | ||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVTGGE--LFDRIVEKGY----YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVE-H----QVLMKTVCGTPGY
|.. |||  |||.||..|.     .|..|    .||..||.|.|..||||||.||||.|         .||.|||.| . . .      ..|| ||.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

CAPEILRG--C-AYGPEVDMWSVGIITYILLCGFEPFYDERG------DQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHP
.||||. |     .||.||.|| |.| | ..||  || |.        ..  .... .|  |.. | | .||  ..|| ||. . .|.|| |  | ..||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP-PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WV
|.
WM
Kinase CaMK4.AA CAMK-Unique 46-300 25 4.4e-91 300.93 In-house 1-363 (363) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-363/363
Sequence Identity: 25% (94 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKK-TVDKKIVRT---------------------EIGVLLRLSHPNIIKLKEI----FETPT-------
 .    .| |. ..||.|. . | | .| |..|| |.  |.  .                     |........||||||| ..    |....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------EISLVLELVTGGELFDRIVE--------------------KGYYSE--RDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAP-----
        .. .|.|...||.||| |..                    .|..||  .|..  . ..|.||||.|...|||||||.||... .. .     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------DAPLKIADFGLSKIVE-HQVL--MKTVCGTPGYCAP--------------EILRGCAYGPEV----DMWSVGIITYILLCGFEPFYDERGDQ
        .  .|..||||.. ..  ..   |.|.|||| |.||              |.. .  |.  .    | || | |.|..|||  ||. |  | 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------FMFRRILNCEY-YFISPWWDE---VSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV
         |..|. ..| .| ...|.    .| .|||.| .. ..||..|..  ..|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CaMK4.AA RSK 46-300 33 1.1e-89 304.26 In-house 1-278 (278) Show / Hide 
Range on Protein: 46-300
Range on HMM: 1-278/278
Sequence Identity: 33% (93 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKK-TVDKKIV-----RTEIGVLLRLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY---
 .|  ..| |. ... .| .. |.. || ||||| ..... .     .||. .|.|   ||.|..|.. |.|.... |..|.. |||||... ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPD-APLKIADFGLSKI--VEHQVLMKTVCGTPGYCAPEILR----GCAYGPEVDMWSVG
 ||..|..   .|  || .||. ||.|||||||| ||.    . . .|. |||..|.   .|  ...| |.|  |.|||.|.    .....  .| || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

IITYILLCGFEPFYDERGD---QFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLT-----TFQALQHPWV
.. | .| |. ||.   .|   .  ..||..... . .| |...| .||||.||.   ||.|||.     . . .|||| 
VLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CaMK4.AA TyrKc 46-299 20 2.8e-14 8.25 SMART 1-280 (280) Show / Hide 
Range on Protein: 46-299
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRL--SHPNIIKLKEIFETP-------TEISLVLELVTGGELFDRIVEKGY-
 . . .||.||  .||... |    . | |.||.   ..  . |. .. .|  .||||..|  .  ..         . .|.|.. .| | |.. ...  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

YSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQ--------VLMKTV-CGTPG-----YCAPEILRGCAYGPE
 . .|  .   || .  .|||.....||||   | |.. .      ||.|||||. ...         . .|.   |. .      .||| .. . . ..
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDMWSVGIITY-ILLCGFEPFYDE----RGDQFMFRRILNCEYYFISPWWDE--------VSLNAKDLVRKLIVLDPKKRLTTFQALQHPW
 | || |.  . |.  | .| ...      .| ..... . ..  . |   .         .    .. ..    ||..|  ||... . .
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP---NDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSEIHECF
Kinase CaMK4.AA Pkinase_Tyr 46-194 26 1.3e-07 26.38 Pfam 1-163 (270) Show / Hide 
Range on Protein: 46-194
Range on HMM: 1-163/270
Sequence Identity: 26% (45 aa)

FEVESELGRGATSIVYRCKQK----GTQKPYALKVLKKTVDKK------IVRTEIGVLLRL-SHPNIIKLKEIFE--TPT-EISLVLELVTGGELFDRIV
 .   .||.||   ||... |    .|. | | |.|| . ...        | |. ..  | .||||..|  .        .| .|.|.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEH
.    |.  .  |  .   || .. .||......||||   | | .    .   ||.||||.. ...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYN