Gene KSR2 (Human)

KSR2

Species: Human
Alias: KSR2, FLJ25965
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 12q24.3,

Classification

Group: TKL
Family: RAF
Subfamily: KSR

Sequence

Name Sequence Type Origin Length Description Download
KSR2.NA RNA Sugen Kinome 15353 None Fasta, JSON
KSR2.AA Protein Sugen Kinome 950 None Fasta, JSON
KSR2.kin_dom Protein Kinase Domain Sugen Kinome 262 None Fasta, JSON

Protein domain

Protein domains of KSR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1 KSR2.AA C1 411-456 22 1.4e-10 42.41 SMART 1-61 (61) Show / Hide 
Range on Protein: 411-456
Range on HMM: 1-61/61
Sequence Identity: 22% (14 aa)

IKHRFSTKYWMSQTCTVCGKGMLF---------GLKCKNCKLKCHNKCTKEAP--------PC
..... ..   . .| .|.| . .         |..| .||.|||.|| . .|        .|
HHWHWWRF--KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_1 KSR2.AA C1_1 413-456 25 4e-06 26.04 Pfam 1-51 (55) Show / Hide 
Range on Protein: 413-456
Range on HMM: 1-51/55
Sequence Identity: 25% (13 aa)

HRFSTK--YWMSQTCTVCGKGM-----LFGLKCKNCKLKCHNKCTKEAPPC
|..  .  . ..  | .||. .     . |.|| .|...||..| . .||.
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPE
Kinase KSR2.AA KSR 666-928 59 1.3e-206 692.72 In-house 1-272 (272) Show / Hide 
Range on Protein: 666-928
Range on HMM: 1-272/272
Sequence Identity: 59% (161 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIE-RDNEDQ-LKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKG-RTLYSVVRDAKIVLDVNK
|..||.||.||||.|..|.|||||||.|.... ...|.. |..||.|||.|..|||||.||||||||.||||||..||||| .|||.........||.|.
LKYGECIGQGRFGKVHRGHWHGEVAIKLYYMDHIHDEHHDLEDFKDEVMMYKNTRHENIVLFMGACMNPPHLAIVMSLCKGSQTLYHHIHVRREKLDMNR

TRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDN-GKVVITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDK---LPFSKHSDVF
|.||||.|..||||||||||.||||||||.||.| |||||||||||||...|....|||.|.|..||||.||||.||...|...|..   ||||.||||.
TMQIAQQICQGMGYLHAKGIIHKDLKSKNIFYENKGKVVITDFGLFSITRLLHCCQREDHLCIPHGWLCYLAPELIRAMRPNYDEYQCMCLPFSHHSDVY

ALGTIWYELHAREWPFKTQPAEAIIWQMGTG--MKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
|.||||||....|||||.|.||.|||||..|  |...|.....|.|...||..||..|..|||||...|.||
AFGTIWYEMICGEWPFKYQCAESIIWQMCQGEGMRQVLRNVQCGREMKEILMMCWSYEPQERPTFQDIMKML
Kinase KSR2.AA RAF 666-928 50 1.9e-175 589.17 In-house 1-275 (275) Show / Hide 
Range on Protein: 666-928
Range on HMM: 1-275/275
Sequence Identity: 50% (138 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIE-RDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSP--PHLAIITSLCKGRTLYSVVRDAKI-VLDVN
..||| ||.||||.||.|.|||.||....... ...|.||.|||.|||.|..|||||.|||||.||.|  ||.||.|..|||.|||......|   .|.|
VQIGERIGQGRFGTVYRGHWHGDVAVKTLNMKYPTPEHQLQAFKNEVMMYKKTRHENIVLFMGYCMKPDNPHYAIVTQWCKGSTLYHHIHVQKTEKFDMN

KTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGKV-VITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDK---LPFSKHSDV
.|.||||.|..||.|||||.|.|.||||||.|..|||| ||||||||.........||...|....||.|..|||.||...||..|..   .|||..|||
WTIQIAQQICQGMDYLHAKNIIHRDLKSKNIFLHNGKVVVITDFGLFTVKRCRWCKRRKQQLCQPHGWICWMAPEVIRMMRPDWDEYQCDCNPFSFQSDV

FALGTIWYELHAREWPFK-TQPAEAIIWQMGTG---MKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
.| ||.||||.|.|||.. .|..|.|||....|   |....... ..||....|..||....||||.|...|.|.
YAFGTVWYELMAGEWPYQHIQWHEQIIWMVCRGYLRMDRSKARVQCPKEMKELLMECWSYQPEERPSFQQIMKMI
Kinase KSR2.AA RAF 666-930 34 5.5e-81 262.28 In-house 1-282 (282) Show / Hide 
Range on Protein: 666-930
Range on HMM: 1-282/282
Sequence Identity: 34% (97 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKA---FKREVMAYRQTRHENVVLFMGACMSPPH---LAIITSLCKGRTLYSVVRDAKI--V
..... || |.|| || |.|||.||.. . ..    .|..|   || || .|..||| |..|||| .|| |.   .||.|  | . .||  .  ..    
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMG-YMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREK

LDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNG-KVVITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTE-----EDKLPF
.| ... .|.. . .|| ||||| |.| ||||.|.| ... .|.|.||||  .   .   |.. .. . ..|   .|||.||.|  |        |..|.
FDMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVK-TRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPY

SKHSDVFALGTIWYELHAREWPF--KTQPAEAIIWQMGTG-MKPNLSQI--GMGKEISDILLFCWAFEQEERPTFTKLMDMLEK
|  |||.. |.. ||| .|. |.    .  . ||.  | | ..| ||..   . | .   .. ||.|..|||| | ... ... 
SFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase KSR2.AA TKL 672-928 21 5.6e-75 255.4 In-house 1-364 (364) Show / Hide 
Range on Protein: 672-928
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)

IGKGRFGQVYHGRWHG-----------EVAIRLIDIERDNEDQL-------------------------KAFKREVMAYRQTRHENVVLFMGACMSPPH-
||.|.||.||.|.|.|           .||.  . .. |.|. .                         . ...|.|  ...||.|.|.|||.|..||. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHA--------KGILHKDLKSKNVFYD-NGK--------------V
            |.|.. .|.| .|....         ... ..|..| .|| |||.        ..|.| ||||||.. | |..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

VITDFGLFS-ISGVLQ--------------AGRREDKLRIQNGWLCHLAPEIIRQLSPDTEE-------DKLPFSKHSDVFALGTIWYELHAREWPFKTQ
 |.||||   .|.  .              . ... ..  | |.....|||..|.  ..||         ....|. .||.. | ...|. .|..|.. .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

PAE---------AIIWQMGT-GMKPNLS-----------QIGMGKEISDILLFCWAFEQEERPTFTKLMDML
| .         ..... .  |..| .               . .......  ||. . |.||.|..... |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase KSR2.AA TKL-Unique 668-928 26 2.3e-40 140.08 In-house 1-290 (290) Show / Hide 
Range on Protein: 668-928
Range on HMM: 1-290/290
Sequence Identity: 26% (78 aa)

IGELIGKGRFGQVYHGRWHGE-VAIRLIDI-ERDNEDQLKAFKREVMAYRQTR-HENVVLFMGACM----SPPHLAIITSLCKGRTLYSVVR--------
....|| | .||||.| |.|. |||  . . |  . . .. |..||      . |.|.|..||.||    .||.. |... | | .||.|          
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-DAKIVLDVNKTRQIAQEIVKGMGYLHAKG--ILHKDLKSKNVFYDNG------KVVITDFGLFSISGVLQAGRREDK------LRIQNGWLCHLAPEII
   .. |. ..  ..|. |..|| ||| ..  |.| ||||.|.  ||.      .. | ||||  ..    ..    .       |. .  .  .|||..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGS--FRWMAPEVL

RQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREW------PFKTQPAEAIIWQMGT---GMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
|..          .|..|||.. |.. .|.  |.       |..    |...    .   .  | ...  . ||..|..  ||. . ..||.|.     |
RMNF-------CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNH-CPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase KSR2.AA Pkinase 666-806 25 2.7e-36 129.43 Pfam 1-158 (293) Show / Hide 
Range on Protein: 666-806
Range on HMM: 1-158/293
Sequence Identity: 25% (41 aa)

LEIGELIGKGRFGQVYHGRWHGE---VAIRLIDIERDNEDQLKAFKR--EVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGR----TLYSVVR-DAK
..||. ||.| ||.||.....|.   ||.  |. ..........  |  |.   .  .|.|.| . .......|. ... .| |      |..... ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IVL--DVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYD-NGKV----VITDFGL
 ..  . .  . .. .|..|. |.|..||.| |||. |...| || .     |.||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase KSR2.AA S_TKc 666-928 21 1e-34 122.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 666-928
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

LEIGELIGKGRFGQVYHGRWHG---EVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKG--RTLYSVVRDAKIV---
 ||...|||| ||.|| .|...   .|||  |.         . ..||.   .. .|.|.| . ... .  || ... .| |   .|... .. .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGKVVITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSK-H
  ..   .| ....|.... |.| .||.| |||  |.. |.  . |.||||  .             . . | .  .|||..            ...|  
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------------TTFCGTPWYMAPEVL------------GYGKCK

SDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMD---------ML
.|. ..| | ||. ... ||     .... ..|             .|  |..  |. .. |.|||  ...           .
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase KSR2.AA Dicty4 666-806 37 4.2e-34 111.26 In-house 1-160 (277) Show / Hide 
Range on Protein: 666-806
Range on HMM: 1-160/277
Sequence Identity: 37% (60 aa)

LEIGELIGKGRFGQVYHGRWHG-EVAIRLIDIERDN--EDQLKAFKREVMAYRQTRHENVVLFMGACM----SPPHLAIITSLC-KGRTLYSVVRD----
. |...|||| ||.|| |.| | |||. .     .|  |. |..|..||    . || |..||||||      |. . | | .. || .|||. .|    
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKG-NLYSLLHDKPSE

--AKIVLDVNKTRQ---IAQEIVKGMGYLHAKG--ILHKDLKSKNVFYDNGKVV-ITDFGL
   .| ||    ..   .|  ...|| .||.    |.| |||| |   |  ..| ..||||
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGL
Kinase KSR2.AA Pkinase_Tyr 666-806 29 1.9e-32 110.49 Pfam 1-157 (270) Show / Hide 
Range on Protein: 666-806
Range on HMM: 1-157/270
Sequence Identity: 29% (47 aa)

LEIGELIGKGRFGQVYHGRWH-------GEVAIRLIDIERDNEDQ--LKAFKREVMAYRQT-RHENVVLFMGACM--SPP-HLAIITSLCKGRTLYSVVR
...|. .|.| ||.||.|.|.        .||.  .  |   ..|  ...| ||.   .|  .|.|.| ..|.|.  . | .. |.. ....  |..  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DA---KIVLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYD-NGKVVITDFGL
.    |  |..    |....| ||| ||..|.. | ||  .|.  . |..| |.||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL
Kinase KSR2.AA DRK 666-806 37 4.6e-30 99.04 In-house 1-146 (258) Show / Hide 
Range on Protein: 666-806
Range on HMM: 1-146/258
Sequence Identity: 37% (55 aa)

LEIGELIGKGRFGQVYHGRWHG-EVAIRLIDIERDN-EDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITS-LCKGRTLYSVVRDAKIVLDVNK
  ||  ||.| .|.|. | | | .||.        | |. |. |.||.    | || |...|||.|  ||   |..  . .|  ||..  | .| .|   
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRG-SLYNILHDESIEMDWPL

TRQIAQEIVKGMGYLHAKG--ILHKDLKSKNVFYDNG-KVVITDFGL
  |..  . ||| |||     |.| |||| |   |   .| . ||||
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGL
Kinase KSR2.AA MLK 666-807 28 3.8e-28 94.8 In-house 1-180 (291) Show / Hide 
Range on Protein: 666-807
Range on HMM: 1-180/291
Sequence Identity: 28% (51 aa)

LEIGELIGKGRFGQVYHGRWHG-E-----VAIRLIDIER----DNEDQLKAFKREVMAYRQTRHEN----VVLFMGACMSPPH-LAIITSLCKGRTLYSV
... | ||.| ||.|. |||.. .     ||.. ....     | . . ..|..|..  |  .|.|    .. |.|.| .||. ..|..  | |  ||.|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

VRDAK-------------IVLDVNKTRQIAQEIVKGMGYLHAKG---ILHKDLKSKNVFYD-------NGKVVITDFGLF
 ..|.             .| |.    ..|  . .|| |||..    | | ||||.|.  |       .|...|.|||..
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS
Kinase KSR2.AA TK 666-806 12 2.1e-25 81.47 In-house 1-297 (486) Show / Hide 
Range on Protein: 666-806
Range on HMM: 1-297/486
Sequence Identity: 12% (38 aa)

LEIGELIGKGRFG---QVYHGRWHG----------------------------EVAIRLID--IERDNEDQLK-------------AFKREVMAYRQ--T
...|. .|.| ||   .|| |.|.|                            .||.  .    . . |...              .. .| .  ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHENVVLFMGACMSP------------PHLAIITSLCKGRT----LYSVVRD-AKIVLDVNKTRQ-----------------------------------
.|.|.| . |.|. .            ... |.. ....      | .  |.  .   .   . .                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------IAQEIVKGMGYLHAK------GILHKDLKSKNVFYDNGK------------VVITDFGL
                                      ... | .|| |||.|      .. | ||   |.  ....            . |.||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL
Kinase KSR2.AA MLK 666-792 34 4.9e-25 79.49 In-house 1-134 (280) Show / Hide 
Range on Protein: 666-792
Range on HMM: 1-134/280
Sequence Identity: 34% (47 aa)

LEIGELIGKGRFGQVYHGRWHGE---VAIRLIDIERDNEDQ---LKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLD
|.| |.|| |.||.|| . |.||   | .   | |.|       .   ..|   .   .|.|..   |.|...||| ..  .|.|  |  |.. ..| ..
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQDPEQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLEDPHLCLVMEYCRGGSLNRVCAGKRIPPH

V--NKTRQIAQEIVKGMGYLHAKG---ILHKDLKSKNV
|  |   |||    .|| |||  .   |.| ||||.|.
VLVNWAVQIA----RGMNYLHNEAPVPIIHRDLKSSNI
Kinase KSR2.AA TyrKc 666-928 22 3.9e-16 38.19 SMART 1-280 (280) Show / Hide 
Range on Protein: 666-928
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

LEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQT--RHENVVLFMGACMSP-------PHLAIITSLCKGRTLYSVVRDAKI
.. |. .| | ||.||.|.|  .||.  .  .      ...| ||    ..   .|.|.| . |.|...       . | |.. ....  | .  |. . 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

VLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGK-VVITDFGLFSISGVL-QAGRREDKLRIQNGWLCH-------LAPEIIRQLSPDTEED
 | . .  ...  | .|| ||| |.. | ||   |. ..... | |.||||    .   |.| ..|  | . .  ..       .||| |         .
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---------N

KLPFSKHSDVFALGTIWYELHAR-EWPFKT-----QPAEAIIWQMGTGMKPNLSQIG-------MGKEISDILLFCWAFEQEERPTFTKLMDML
.  |.  |||.. |   .|.  . . |         ... .| .  .|. .   . .       . .|. .| . ||... |.||||. . . .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase KSR2.AA TK 901-928 39 3.2e-07 19.46 In-house 459-486 (486) Show / Hide 
Range on Protein: 901-928
Range on HMM: 459-486/486
Sequence Identity: 39% (11 aa)

KEISDILLFCWAFEQEERPTFTKLMDML
.|. |... ||... |.||||. | ..|
EEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase KSR2.AA MLK 851-928 25 2e-06 16.99 In-house 203-280 (280) Show / Hide 
Range on Protein: 851-928
Range on HMM: 203-280/280
Sequence Identity: 25% (20 aa)

FSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQIGMG--KEISDILLFCWAFEQEERPTFTKLMDML
.|| |||   | .  ||  .| |..   . |. ..     | .|. |.       . ..  ||. .  .||.|..... |
WSKGSDVWSYGVLLWELLTGEVPYRGIDPLAVAYGVAM-NKLTLP-IPSTCPEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase KSR2.AA MLK 833-928 23 5e-06 17.07 In-house 201-291 (291) Show / Hide 
Range on Protein: 833-928
Range on HMM: 201-291/291
Sequence Identity: 23% (23 aa)

APEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREWPFK-TQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDML
|||.| |          ..|. .||.  | . .|...|| |.|  . . ||.|...   .     ..  . ..  .  ||  . ..||.|   .  |
APEVIQQ------FRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase KSR2.AA Pkinase_Tyr 901-928 39 4.1e-05 17.93 Pfam 243-270 (270) Show / Hide 
Range on Protein: 901-928
Range on HMM: 243-270/270
Sequence Identity: 39% (11 aa)

KEISDILLFCWAFEQEERPTFTKLMDML
.|| |... ||... |.||||. .  .|
DEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase KSR2.AA Pkinase 832-928 16 0.011112 10.56 Pfam 178-293 (293) Show / Hide 
Range on Protein: 832-928
Range on HMM: 178-293/293
Sequence Identity: 16% (21 aa)

LAPEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHAREWPFKTQ------PAEAIIWQMGT----GMKPNLSQIG---------------MGKEISDI
.|||.||        .  . .. .|....| | ||.  .. ||. .         ..| . .        |... |                . .|  |.
MAPEVIR--------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

LLFCWAFEQEERPTFTKLMDM--L
.  |...  ..|||.. ..    .
IKWCLCKDPKKRPTAEQILQHPWF