Gene LMR2 (Human)

LMR2

Species: Human
Alias: BREK, LMTK2, AATYK2, LMR2, KIAA1079, KPI2, cprk, KPI-2
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 7q21.3,

Classification

Group: TK
Family: Lmr

Sequence

Name Sequence Type Origin Length Description Download
LMR2.NA RNA Sugen Kinome 8961 None Fasta, JSON
LMR2.AA Protein Sugen Kinome 1503 None Fasta, JSON
LMR2.kin_dom Protein Kinase Domain Sugen Kinome 274 None Fasta, JSON

Protein domain

Protein domains of LMR2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LMR2.AA Lmr 137-410 66 1.3e-228 765.81 In-house 1-283 (283) Show / Hide 
Range on Protein: 137-410
Range on HMM: 1-283/283
Sequence Identity: 66% (188 aa)

LNYIQEIGNGWFGKVLLGEIYT---GTSVARVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRSEQ--E
|||||||||||||||||||...   |.|.|.|.||||.|||.|.||..||....||..|||||.|||.|||||.||||||.|||..||||.|||...  |
LNYIQEIGNGWFGKVLLGEVHSLHPGMSKAQVVVKELRASASPQEQMQFLQEVQPYRELQHPNVLQCLGQCVETIPYLLVMEFCPYGDLKNYLRKCRPME

HMRGDS---QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDDK-KVFPLRWTAPELVTSFQDRLLTADQT
||..|.   |||.|||||||.|.|||.||..||.|||||||||.|..||.||.||||.....|||||..|.|. ...||||.||||...|...||..|||
HMMPDKPPRQTMTLQRMACEIACGLAHMHQHHFVHSDLALRNCQLCADLTVKIGDYGLAHCQYKEDYYITKDQCHWVPLRWIAPELMDEFHQNLLVVDQT

KYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLSPEKRPAAEDVHRLLTYL
|||||||||||.||||..|||||...|...||.||.||.|.|||||||..||||||||..||||..|..||.|||||||||||
KYSNIWSLGVTMWELFEFAAQPYPHHSDEQVLAQVVREQDIKLPKPQLQLPYSDRWYEIMQFCWMQPDQRPTAEDVHRLLTYL
Kinase LMR2.AA TK 137-407 16 2.3e-72 241.68 In-house 1-486 (486) Show / Hide 
Range on Protein: 137-407
Range on HMM: 1-486/486
Sequence Identity: 16% (81 aa)

LNYIQEIGNGWFG---KVLLGEIYTGT-----------------------SVARVIVKELK--ASANPKEQDT--------------FLKNGEPYY--IL
. .....| |.||   .| .|| ...                         . .| || ||  ......|.                ..   .     ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHPNILQCVGQCVEA------------IPYLLVFEFCDLGD----LKAYLRSEQEHMRG-----------------------------------------
.||||....| |..              |...| |....||    |. |||.  ....                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------DSQTMLLQR-------------------MACEVAAGLAAMHKL------HFLHSDLALRNCFLTSDLN-----------VKVGDYGIG--
          . .|  | .                   |.. .|.|.. .|..      .| | ||| ||| ......           .|..|.|    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----FSR---YKEDYIETDD-----------------------KKVFPLRWTAPELVTSFQDRLL--TADQTKYSNIWSLGVTLWELFDNA-AQPYSNLS
     .|   ...||  ...                       .  .|.||.||| ... . .    .   |  | .||.||..||.| .. ...| ..|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------LDVLNQVIR----------ERDTKLPKPQLEQPYS-------------DRWYEVLQFCWLS-PEKRPAAEDVHRLL
|          .|.... |          |   ....|| ..  .             . .|...| ||   ||.||  ...|. |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LMR2.AA Pkinase_Tyr 137-407 27 7.8e-49 166.02 Pfam 1-270 (270) Show / Hide 
Range on Protein: 137-407
Range on HMM: 1-270/270
Sequence Identity: 27% (79 aa)

LNYIQEIGNGWFGKVLLGEIY--TGTSVARVIVKELKASANPKE--QDTFLKNGEPYYIL-QHPNILQCVGQCV-EAIP--YLLVFEFCDLGDLKAYLRS
.  ....| | ||.| .|. .   .     | || || .| ...  .. |..  .    | .||||....| |. .  |  ...|.|.. .|||. |||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

EQEHMRGDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYK--EDYI-ETDDKKVFPLRWTAPELVTSFQDRLLTAD
   . ..   .  |  |. ..|.|..  .  .. | ||| ||| .|... ||..| |   .|.   .||   . ..  .| .|.|||             
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL--ARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-------

QTKYSNIWSLGVTLWELFDNAAQP-YSNLSNLDVLNQV-IRERDTKLPKPQLEQPY--SDRWYEVLQFCW-LSPEKRPAAEDVHRLL
 |  | .|| ||..||.|   .|| | ..|| .|....  .         ....|   .|  |.... ||   ||.||  ...|. |
FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED-------GYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase LMR2.AA UTK 137-407 25 2.1e-48 163.72 In-house 1-296 (296) Show / Hide 
Range on Protein: 137-407
Range on HMM: 1-296/296
Sequence Identity: 25% (79 aa)

LNYIQEIGNGWFGKVLLGEIYTGT---SVARVIVKELKASAN-PKEQD---TFLKNGE---PYYILQ-HPNILQCVGQCVEAIPYLLVFEFCDLGDLKAY
.   ...| | || | ...  . .    ...| ||.....|. ..|..   .|..       .  .. |||.|. || |.   | ..| |..  ||| .|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LR-SEQEHM-RGDSQTML-LQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSD-------LNVKVGDYG-------IGF----SRYKEDYIETDD-KKV
|| . .. . .....|.  .  ||  .|.|.. .|  .| | ||| |||.....       . .|..|.|       ...    .||.|.| .. .  . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRE-RDTKLPKPQLEQ--PYSDRWYEVLQFCWLS-PEKRPA
 |.||.||| .|.        . |  | .||.||..||.. ....|| ..|| .|. || .  |       ....    ... |.... || . |..|| 
WPIRWMAPEALTHHT------RFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGR------YRMPCPWDCPHPVYRLMHRCWHYDPQERPD

AEDVHRLL
.||.   .
FEDLVQQM
Kinase LMR2.AA Trk 137-407 30 2.7e-42 141.14 In-house 1-275 (275) Show / Hide 
Range on Protein: 137-407
Range on HMM: 1-275/275
Sequence Identity: 30% (88 aa)

LNYIQEIGNGWFGKVLLGEIYTGTSVAR---VIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRS---EQ
.  ..|.| | |||| |.| |          | || ||  .. .   .| .  |    |||..| .  | |..  | |.|||.   |||. |||.     
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

EHMRGDSQ--------TMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYK-EDYIETDDKKVFPLRWTAPELVTSFQDRL
. . .              .   | ..|.|.  |  .|| | |.| |||    .| ||.||.|     |   ||   . .   | ||  ||   | . | 
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPE---SIMYRK

LTADQTKYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERD-TKLPK--PQLEQPYSDRWYEVLQFCW-LSPEKRPAAEDVHRLL
 | .    | .||.||..|| |    ||.  |||. | . .   |   . |.  ||         |...  ||   |..|  . |.| ..
FTYE----SDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQ-------EVYDIMLGCWQREPQQRMNIKDIHDII
Kinase LMR2.AA TyrKc 137-407 26 3.2e-41 144.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 137-407
Range on HMM: 1-280/280
Sequence Identity: 26% (82 aa)

LNYIQEIGNGWFGKVLLGEIYTGTSVARVIVKELKASANPKEQDTFLKNGEPYYIL--QHPNILQCVGQCVEA-------IPYLLVFEFCDLGDLKAYLR
.  ....|.| ||.| .|. .       | || ||..|    .  |..  .    |  .||||....| |..         |...|.|....|||| |||
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SEQEHMRGDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKE---------DYIET----DDKKVFPLRWTAPELV
. ...     ..  |  ..  .|.| .  |. .. | ||| ||| ..... ||..| |   ||. .         ||. .    . | ..|.||.|||  
KHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL--SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

TSFQDRLLTADQTKYSN---IWSLGVTLWELFDNAAQPYSN-----LSNLDVLNQVIRERDTKLPKPQLEQP-----YSDRWYEVLQFCWLS-PEKRPAA
          .  |..    .|| ||..||.| . .|||..     .|| .|...| . .  . |.  .  |      .|  |.. . ||   ||.||  
----------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTF

EDVHRLL
...|...
SEIHECF
Kinase LMR2.AA TK-Unique 137-406 28 6.2e-41 138.92 In-house 1-294 (294) Show / Hide 
Range on Protein: 137-406
Range on HMM: 1-294/294
Sequence Identity: 28% (86 aa)

LNYIQEIGNGWFGKVLLGEIYTGT---SVA-RVIVKELKASANPKEQDTFLKNGEPYYILQ-HPNILQCVGQCVEA-IPYLLVFEFCDLGDLKAYLRSEQ
|.  ..|| | || |  ||. ...   .   .|.|| ||..|.. ... |||. . .  |  ||||.||.|.|..  .| ....|.|  |.|  |||. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

----------------EHMRGDSQTMLLQ-----RMACEVAAGLAAMHK--LHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRY---KEDYIETDDKKVF
                .||. . .|  ..     . |...| |.. ...   .. | ||. ||..||.|...|..|.|.  .|.    ..|. .. ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM--ARDVYTNGVYSMMCSQGRI

PLRWTAPELVTSFQDRLLTADQ-TKYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPY-SDRWYEVLQFCW-LSPEKRPAAE
|.|| |||          .    |  |..||.||..||.| . |.||..... |..... .  .  .|.|.    . |.. |.... || ..||.||  .
PIRWMAPESLKCY-----HGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYR--MPQPEH---CCSHEMYNLMKSCWQWEPEERPSFR

DV-HRL
.. |||
QIKHRL
Kinase LMR2.AA InsR 137-409 30 2.3e-35 116.16 In-house 1-278 (278) Show / Hide 
Range on Protein: 137-409
Range on HMM: 1-278/278
Sequence Identity: 30% (88 aa)

LNYIQEIGNGWFGKVLLG---EIYTGTSVA--RVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRSEQE
.  |.| | | ||.| .|    |  .   .  |. .| ....|  .|   ||.  .      . ..    | |    | . | |. ..|||| ||||  .
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

HMR---GDSQ----TMLLQR---MACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRL
 ..   .. .     . |..   || |.. |.|    . | | ||| |||    |. ||.|| |     |  ||     |   | || |||   |  |  
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPE---SLKDGV

LTADQTKYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPY--SDRWYEVLQFCW-LSPEKRPAAEDVHRLLTY
 |.    .| .||.|| |||    ..|||  |||  ||. . ...        |..|   ...|.|. . ||  .|  || . |.  .|  
FTT----HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNV------LRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase LMR2.AA Frk 137-410 29 3.1e-31 105.26 In-house 1-260 (260) Show / Hide 
Range on Protein: 137-410
Range on HMM: 1-260/260
Sequence Identity: 29% (83 aa)

LNYIQEIGNGWFGKVLLGEIYTGTSVARVIVKELKA-SANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRSEQEHMRG
. .|...| | ||.|  |     | ||   ||.||. ...|..   ||..      |.|| ..|    |    | ... |    | |. ||.. ... | 
IQLIRRLGSGQFGEVWEGLWNNTTPVA---VKTLKPGTMDPND---FLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGR-

DSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDY--IETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIW
  |   |  ||  ||||.| . .  ..| ||| ||  .  .. .|. |.|.     |..    |.     ||..||||| .        .   |  | .|
QCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAAN-------YNKFTIKSDVW

SLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLS-PEKRPAAEDVH-RLLTYL
| |. | |.      ||. . | .||..|  ... ..|.|   ..   . ||... || | |.|||  | .. .|  |.
SFGILLTEIITYGRMPYPGMTNAEVLQMV--DHGYRMPQPPNCPQ---QLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase LMR2.AA Fer 137-408 24 2.5e-30 100.54 In-house 1-283 (283) Show / Hide 
Range on Protein: 137-408
Range on HMM: 1-283/283
Sequence Identity: 24% (73 aa)

LNYIQEIGNGWFGKVLLGE-----IYTGTSVA---RVIVKELKASANPKE-QDTFLKNGEPYYI-LQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYL
 . .  .|.| ||.| .|.     .  ...|     | || .|...  || .  |..        ..|||. .. | ||   |...|.|||. |.|. ||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RSEQEHMRGDSQTM-LLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTS-DLNVK--VGDYGIGFS--RYKEDYIETDDKKVFPLRWTAPELVTSFQDR
. ...     . ..  . ||. ..|.|.. .|. . .| |.| ||| ..  ....|  . | |      .|..|| . .  .  | ||.||| ....   
KKNKNK----TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTG---

LLTADQTKYSNIWSLGVTLWELFDNAAQPYSN----LSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQ-FCWL-SPEKRPAAEDVHRLLT
      .. . .|| ||..|| | |.|.|| .    . .  | .| ..   .|   .....   .. ....   ||   ||.|| . .... | 
----IYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase LMR2.AA DDR 137-407 24 1.6e-29 100.15 In-house 1-306 (306) Show / Hide 
Range on Protein: 137-407
Range on HMM: 1-306/306
Sequence Identity: 24% (77 aa)

LNYIQEIGNGWFGKVLLGEIYTGT------SVAR--------VIVKELKASANPKEQDTFLKNGEPYYILQ-HPNILQCVGQCVEAIPYLLVFEFCDL-G
|.    || | || | | |.  .       .           | || |.. |.      |.|       .  ||||   || |..  ||... |.    |
LIFVEKIGEGQFGEVHLCEVEGMQDYIEFDFHCDVHKGHPTLVAVKMLRPDACKHARNDFHKEIKCMSQCKRHPNIVRLVGVCTQDEPYCMIMEYMENLG

DLKAYLRSEQEH---MRGDS-----------QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYG--IGFSRYKEDYIETDD----
||. ..   .       . .           ..  . ...  .|.|..    . | | ||| |||    ....|. | |  .  . |  ||   .     
DLNQFWMEHEAENSGLMNCKADTQNCQKPTISYECCVYICTQIASGMKYLESMNFVHRDLATRNCLVGKEYHIKICDFGTVMSRNLYSQDYYRVEGFTGR

-KKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFDNA-AQPYSNLSNLDV---LNQVIRERDTK--LPKPQLEQPYSDRWY-EVLQFCWL
 . . |.|| |.| .       |    |  | .|. |||.|| |  . .|||. |.. .|   . .  |.  ..  ||.| .     .  | . .  || 
QRHHMPIRWMAWESI-------LLGKFTTKSDVWAFGVTMWEMFMFCREQPYEQLTDEQVIENACEFFRHQGMQVYLPMPPM---CPYEIYNQLMCRCWR

S-PEKRPAAEDVHRLL
. ...||  | .|..|
RDQSQRPSFEEIHKFL
Kinase LMR2.AA Tec 137-409 31 4.5e-29 98.78 In-house 1-254 (254) Show / Hide 
Range on Protein: 137-409
Range on HMM: 1-254/254
Sequence Identity: 31% (89 aa)

LNYIQEIGNGWFGKVLLGEIYTGTSVARVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRSEQEHMRGD
|  ..|.|.| || | ||.      ||   .||   |    | | |.   .    |.||.  |  | |..  |  .|.|.   | |  |||... |..  
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMS----EED-FIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQ--

SQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKED--YIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKY---SN
... .|  |  .|  | |   .  |.| ||| |||   ..  ||| |.|.  .||  |  |.     | || .| .|| | ..         ..|   | 
KNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGM--TRYVLDDQYTSSVGTK-FPVKWCPPE-VFHY---------SRYSSKSD

IWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWL-SPEKRPAAEDVHRLLTY
.|. ||  || |    .|| |.||..|  .| .    .| .|.|    |.. |..   ||  .||.||. ..  | .| 
VWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQG--HRLYRPHL---CSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase LMR2.AA S_TKc 137-410 19 7.3e-17 63.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 137-410
Range on HMM: 1-231/231
Sequence Identity: 19% (55 aa)

LNYIQEIGNGWFGKVLLGEIYTGTSVARVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDL--GDLKAYLRSEQEHMR
   ...|| | |||| ..      .  .| .|..|     .| .   |        .|||| .. . ...   . .|.|.||   |||. |... . | .
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

GDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSN---
.   .   ........ .|. .|.....| ||   | .|..  ..|..|   |..|         .  .  . . |||..             .|.    
RFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDF--GLARQL-------TTFCGTPWYMAPEVL-------------GYGKCKC

-IWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWL-SPEKRPAAEDVHR------LLTYL
 .||.|..|.|..     |..   ..... ..|.               |.   . .. |.   ||||| | .. .      .  ..
DWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LMR2.AA Pkinase 137-286 22 9.9e-10 35.49 Pfam 1-158 (293) Show / Hide 
Range on Protein: 137-286
Range on HMM: 1-158/293
Sequence Identity: 22% (37 aa)

LNYIQEIGNGWFGKVLLG-EIYTGTSVARVIVKELKASANPKEQDTFLKN-GEPYYI--LQHPNILQCVGQCVEAIPYLLVFEFCDLG----DLKAYLRS
.  .. || | ||.| .. .. ||    .| ||..| . . ...|  . .  | ..   |.||||... . . .   . .|.|.|. |    ||..|.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

EQEHMRGDS--QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNV----KVGDYGI
   ...|    .   ..... ... ||. .|.  ..| || . |... .. ..    |..| |.
---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGL
Kinase LMR2.AA Pkinase 332-343 41 3.025657 1.95 Pfam 195-206 (293) Show / Hide 
Range on Protein: 332-343
Range on HMM: 195-206/293
Sequence Identity: 41% (5 aa)

IWSLGVTLWELF
.||.|..|.|..
MWSCGCILYEML