MAST3

Species: Human
Alias: KIAA0561, Hs.173864, MAST3
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 19p13.1,

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
MAST3.NA RNA Sugen Kinome 5993 None Fasta, JSON
MAST3.AA Protein Sugen Kinome 1331 None Fasta, JSON
MAST3.kin_dom Protein Kinase Domain Sugen Kinome 274 None Fasta, JSON

Protein domain

Protein domains of MAST3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF1908 MAST3.AA DUF1908 160-354 70 3e-143 486.97 Pfam 168-369 (369) Show / Hide
Range on Protein: 160-354
Range on HMM: 168-369/369
Sequence Identity: 70% (142 aa)

VLDEE----GGRSPRLRPRSRSL-SPGRATGTFDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYA--PGARLALADGVLGFIHHQIVELARDCLAKSG
. ||.    |.|||..||||||| ||.|. .|||||||||||||.|||||||.|||.|||.|.....  |  .|.|||.|..|||||.||.|||||.|| 
CQDEDNNFCGCRSPHHRPRSRSLSSPSRSCITFDNEIVMMNHVYKERFPKATQQMEERLQHFIHHFKNIPCDSLRLADPVVRFIHHQVVEMARDCLHKSH

ENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLE
. |.|||||.||||||||||..|||||.|||| ||.....||||||||||||||||||||||||||||||||.|...||||||.|.||| ||||..||.|
AKLITSRYFYEMQEKLERLLHEAHERSESEEVPFITHVIKKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAKVMQGIKTDIPRYIIHQLGLNRDPIE

EM
||
EM

DUF1908 MAST3.AA DUF1908 80-159 65 7.2e-48 170.15 Pfam 1-94 (369) Show / Hide
Range on Protein: 80-159
Range on HMM: 1-94/369
Sequence Identity: 65% (62 aa)

PLDSPRNFSAASALNFPF--AR-------RADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERL----HQLPFQPTPDELHFLSKHFRSSE-N
|.|||||||..|..||||  .|       ||||||||.|||||||||||.|||..||..||.|||    |||||||| |.||||||||...| |
PIDSPRNFSTSSMMNFPFVPIRRITNCRDRADGRRWSVASLPSSGYGTNPPSSNVSSQCSSQERLNQLPHQLPFQPTQDDLHFLSKHFCCTESN

Kinase MAST3.AA MAST 389-662 53 1.4e-230 712.68 In-house 1-337 (337) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-337/337
Sequence Identity: 53% (180 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFET--RRHLCMVMEYVEGGDCATLLKNMG-PLP
||.||.||.|||||||||.|..|..|||.|.||.|..|..||..||||||.|||...|||||.||.||.|  ...|||||||.||||||.||...| ..|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

VDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEG---------------HIEKDAREFI------------
..||..|.|||||.|||||.||||||||||||.||.|.||||||||||||.|.|...||.|||               ||.|....|             
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

------------------------DKQVCGTPEYIAPEVIFRQG-YGKPVDWWAMGVVLYEFLVGCVPFFGDTPEE-LFGQVVS--DEIMWPEG-----D
                        .||.||||.|||||||..|| ||||||||.||...|||||||.||.|||||| .|.....  .||.|||.     |
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

EALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFF
......||||| .||.. |..|||..| .|.||||||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF

Kinase MAST3.AA MAST 389-662 50 3.5e-211 687.5 In-house 1-334 (334) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-334/334
Sequence Identity: 50% (170 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDM
||.||.||.||||.||||.|..|..|||.|.|.|...|..|...||.|||.||....|||||.||.||.|...|||||||.||||||.||...|.....|
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEG---------------HIEKDAREFI---------------
|..|.|||||.|||||..|||||||||||.||.|.||||||||||||.|.|......|||               ....|...|                
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

--------------------DKQVCGTPEYIAPEVIFRQG-YGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDE---IMWPEG-----DEALP
                    .||.||||.||||||| .|| .|||||||.||...|||||||.||..|||||.|.......   |.||||     |||..
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

ADAQDLITRLLRQSPLDRLGTG-GTHEVKQHPFF
 .||||| .|| . |..|||.. | .||||||||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF

Kinase MAST3.AA AGC 389-662 29 2.2e-171 447.49 In-house 1-395 (395) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-395/395
Sequence Identity: 29% (117 aa)

FETIKLISNGAYGAVYLVRHR------DTRQRFAIKKINKQN-LILRN--QIQQVFVE------------RDILTFAE----------NPFVVS-MFCSF
|| .|.|. |..| |||||..      || . .|.|...|.   ....  ..... .|            |.||. .           .||.|. ...||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETRRH--LCMVMEYVE--------GGDCATLLKNMG-----PLPVDMARLYFAE-------TVLALEYLHN-YGIVHRD-LKPDNLLITSLGHIKLTDFG
.. .|  |..||||..        ||.| ..| ..|      .. ..|| |.||       .||||||||.  ||.||| |||.|.|... |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKIGLMSM-----------ATNLYEG---------------HIEKDA----------REFIDKQVCG--TPEYIAPEVIFRQGYGKPVDWWA--MGVVL
|.|.| ...            .. ...               .. ...           ..  .  ||  ||||.|||..    |||..|||.  .|...
LCKEGMNDGEKGQQSQSNMKFHW-HNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YEFLVGCVPFFGDTPE----------ELFGQVV------SDEIMWP-------EGDEALPADAQDLITRLLRQSPLDRLGTG-------GTHEVKQHPFF
||.|.|. ||.||.|.          |.| ..       .... .|       ..|. .  .|.|||..||   | .|||.|       |. |.|.||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase MAST3.AA S_TKc 389-662 32 2.1e-101 344.09 SMART 1-231 (231) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-231/231
Sequence Identity: 32% (93 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEG--GDCATLLKNMGP---
.| ...|  ||.| ||..||..| ...|||.|.          ...  |..||     |..| .. .|..  ||.|||||..|  ||  ...|..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYG
   .|  .|| |......||||.|. ||.||||||.|.|...  |||..||||...                       . .||||.|.||||.   |||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------TTFCGTPWYMAPEVL---GYG

K-PVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHE----VKQHPFF
| ..|||. |..|||.|.|. ||   .....| ...             . .| |.| ..|.  | .|..     .    .|.||.|
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MAST3.AA RSK-Unclassified 389-662 37 2.5e-92 290.28 In-house 1-283 (283) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-283/283
Sequence Identity: 37% (108 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLK--NMGPLPV
|. ..||  |  | ||||| .|| | .|.|  .|. .| .| |. |  |..|.   . ||.| .. || |.  | ..|||  |||    |       .  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

DMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIG------LMS--MATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQG
| .| | .|...||||||  ... ||||||| .    ||..||||.||. .       |       . .  |  .   |  .  ||| ||.|||.| | |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHG--FRTNSFCGTEEYLAPEMIRRCG

YGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTG-G-THEVKQHPFF
 .| |||| .|.|.|| |.|| |. |.  .|.|  .   ..  |. |. .  ...||| .|| . |  ||| . |   ..|.||||
HTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPH-DSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF

Kinase MAST3.AA AktR 389-662 36 3.7e-89 302.52 In-house 1-268 (268) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-268/268
Sequence Identity: 36% (103 aa)

FETIKLISNGAYGAVYLVRHR-DTRQRFAIKKINKQNLILRNQIQQVFVERDILT-FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPV
|. .|.. .||.| ||||... |. . .|.| | |...| |||....  ||.|.   . .|| | .. .|.|...|  .|||..||.  . ||. . .  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DMARLYFAETVLALEYLHNY-GIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDA-REFIDKQVCGTPEYIAPEVIFR-QGYGKPV
..|| |||. .|||||||.   |. |||||.|.|. . ||.|.|||||||              ....  .. . . .||||||.|||.|.. .|..|.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSV

DWWAMGVVLYEFLVGCVPFFG-DTPEELFGQVVSDEIMWPEGDEALPADAQDLIT-RLLRQSPLDRLG--TGGTHEVKQHPFF
|||| |...|| ..|| ||.  .. .... .  .. .  ..  . .   ..|||. .|| . |  |||  . |. |.| ||.|
DWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase MAST3.AA Pkinase 389-662 28 8.8e-82 282.8 Pfam 1-293 (293) Show / Hide
Range on Protein: 389-662
Range on HMM: 1-293/293
Sequence Identity: 28% (88 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFV--ERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGG----DCATLLK--N
..... |  |..| ||. .|..|....|.|.|.|.  .  .. |. .   |  |.     |..| ....||...|..|||||.|||    | .....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

MGPL--PVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHI----KLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVI
 |..  . . .. |. ... .|||.|. ||.||||||.|.|| . |||    |..||||.|               .   . .  . .||||.|.|||||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------Y-NNS-M--TTFCGTPWYMAPEVI

F-RQGYGKPVDWWAMGVVLYEFLVGCVPFFGD------TPEELFGQVVSDEIMWPEGDE------------------ALPADAQDLITRLLRQSPLDRLG
  .|.||..||.|..|..|||.| |  || |.      .. ... .. . ......  .                  ... ...|.|...|.. | .|..
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

TGGTHEVKQHPFF
    ....|||.|
---AEQILQHPWF

Kinase MAST3.AA RSK 392-662 34 1.1e-81 277.68 In-house 1-278 (278) Show / Hide
Range on Protein: 392-662
Range on HMM: 1-278/278
Sequence Identity: 34% (101 aa)

IKLISNGAYGAVYLVRHR---DTRQRFAIKKINKQNLILRNQ-IQQVFVERDILTFAE-NPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGP---
.|.   |.||.|.|.|     ||.| .| | ..|  .. |.  .  .. ||.||   .  ||.|. . .|.|  .| ..|||..||.  | |.. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITS---LGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIF----R
.  | |. |.|| |||.|.||  ||.||||||.| | ..    |||||||||..|..  ..   ..                |.| ||.|||..     .
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT--------------FCYTIEYMAPEMLKRANQQ

QGYGKPVDWWAMGVVLYEFLVGCVPFFG---DTPEELFGQVVSDEIMWPEGD--EALPADAQDLITRLLRQSPLDRLG--TGGTHEVKQHPFF
 |..| .|||  ||..|| |.||.|| |   ....|.. .. . .   ....  . | ..|.|||...|   | .|||   ... |.||||.|
GGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK-FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase MAST3.AA NDR 389-535 48 2.1e-80 247.59 In-house 1-152 (350) Show / Hide
Range on Protein: 389-535
Range on HMM: 1-152/350
Sequence Identity: 48% (73 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAE--NPFVVSMFCSFETRRHLCMVMEYVEGGDCAT---LLKNMGP
|| ||.|. ||.| |.|||..||.. .|.|...|.  . .||. .|  ||||.. |   ||.||....||    .|. ||||. |||  |   ||..|. 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSK
.. |.|| | ||.|.|.|..|..|..|||.||||.|| . ||||||||||..
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCT

Kinase MAST3.AA PKA 389-535 42 2.3e-54 186.95 In-house 1-149 (263) Show / Hide
Range on Protein: 389-535
Range on HMM: 1-149/263
Sequence Identity: 42% (64 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVV-SMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVD
||.|... .| .| |.|.||... . .|.| ..||  . ..|.. |  |. ||.  ..||.| .|  .| ..|.| ||||||.||.  . | . | .. .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

MARLYFA-ETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSK
.|..| | . ||||||||.  |..||||| |.|| . ||||.|||| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK

Kinase MAST3.AA Akt 389-540 39 1.4e-52 166.34 In-house 1-154 (264) Show / Hide
Range on Protein: 389-540
Range on HMM: 1-154/264
Sequence Identity: 39% (61 aa)

FETIKLISNGAYGAVYLVRHRDTRQRF-AIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVD
|. .|..  |..| |.||.  || . . |.| . |. .| .||..... || ||    .||.|..  || |  .|..||.|. ||.  ..|.  .  . |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

MARLYFAETVLALEYLHNYGIVHRD-LKPDNLLITSLGHIKLTDFGLSKIGLMS
 || | || .||.|.||. .|. || ||| |.|. . |||.||||||.| ....
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIK

Kinase MAST3.AA SGK 389-535 36 1.3e-51 157.43 In-house 1-173 (283) Show / Hide
Range on Protein: 389-535
Range on HMM: 1-173/283
Sequence Identity: 36% (63 aa)

FETIKLISNGAYGAVYLVRHRDT------------------RQRFAIKKINKQNLI-------LRNQIQQVFVER-DILTFAENPFVVSMFCSFETRRHL
|. .|.|  | .| ||.|.| |.                   . .|.| ..||  |        ...   .  || .||     || |.   .| |   |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSK
 .||.||.||.    |.  . .| | || | || |.||||||   |..|||||.|.|  . ||..||||||.|
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK

Kinase MAST3.AA NDR 564-662 43 3.2e-43 130.75 In-house 243-350 (350) Show / Hide
Range on Protein: 564-662
Range on HMM: 243-350/350
Sequence Identity: 43% (47 aa)

GTPEYIAPEVIFR-QGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMW-----PEGDEA-LPADAQDLITRLLRQSPLDRLG-TG-GTH
|||.|.||||. . .||.. .|||  |...||.|||  ||..|||.| .  . . ...|       . || |  .|.|||.||.   |  |||  | | .
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD

EVKQHPFF
|.|.||||
EIKSHPFF

Kinase MAST3.AA Akt 562-662 36 2e-39 123.6 In-house 162-264 (264) Show / Hide
Range on Protein: 562-662
Range on HMM: 162-264/264
Sequence Identity: 36% (38 aa)

VCGTPEYIAPEVIFRQGYGKPVDWWA-MGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLG--TGGTHEVKQ
.||||||.|||..  .|..|.||||.  |.|.||.. |  ||. .  ...| .  . ..  |.  ...  ...|||..||   |  |||   ....|.|.
FCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDK-DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKR

HPFF
||.|
HPWF

Kinase MAST3.AA SGK 563-662 41 5.3e-39 117.76 In-house 186-283 (283) Show / Hide
Range on Protein: 563-662
Range on HMM: 186-283/283
Sequence Identity: 41% (42 aa)

CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTG-GTHEVKQHPF
|||||| ||||.  |.... |||| .| ||||...|  ||.    .... .  . ..  | .     .|| |||. ||   | .||||  .  |.|.|||
CGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQ---MSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPF

F
|
F

Kinase MAST3.AA PKA 562-662 37 4.1e-32 113.0 In-house 158-263 (263) Show / Hide
Range on Protein: 562-662
Range on HMM: 158-263/263
Sequence Identity: 37% (41 aa)

VCGTPEYIAPEVIFRQ-GYGKPVDWWAMGVVLYEFLVGCVPFFGD--TPEELFGQVVSDEIMWPEGDEALPADA---QDLITRLLRQSPLDRLGT--GGT
.||||||.|||.| .  |.||.||||| |.. ||.|.|  ||. .  .| ...   .. .| .|. .     ||    ||| .||   .  |.|.  .|.
LCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFD---SDANYFKDLIKKLLQVDLTKRYGNMKNGV

HEVKQHPFF
  .| |..|
NDIKNHKWF

Kinase MAST3.AA TyrKc 389-648 18 2e-13 -5.46 SMART 1-280 (280) Show / Hide
Range on Protein: 389-648
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

FETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFA--ENPFVVSMFCSFETR-------RHLCMVMEYVEGGDCATLLK
 . .| . .||.| ||. . .   .  |.|....        ..    |  |..    ..| .| ..    .          |..||||...||.   |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NMGP-LPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMS----MATNLYEGHIEKDARE-FIDKQVCGTPEYIAPEV
. .| |...    .        ||||  ...||||   | |... ...| .|||||. .        ..  |    .|...  .  .         |||.
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-------WMAPEC

IFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGD------TPEELFGQVVSDEIMWPEGD-------EALPADAQDLITRLLRQSPLDR---------L
|.   .    | |. ||...| .  . .   .      ...|.. .| . . | .  .       .. ..  | ....  .  | ||         .
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF

Kinase MAST3.AA Pkinase_Tyr 461-535 30 9.1e-08 26.93 Pfam 81-159 (270) Show / Hide
Range on Protein: 461-535
Range on HMM: 81-159/270
Sequence Identity: 30% (24 aa)

HLCMVMEYVEGGDCATLLKNM----GPLPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSK
....||||...||  . |..     .||.. .   . ..   ..|||.. ...||||   | |.|. ...| .||||..
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR

Kinase MAST3.AA S_TK_X 663-726 17 0.00087 8.22 SMART 1-79 (79) Show / Hide
Range on Protein: 663-726
Range on HMM: 1-79/79
Sequence Identity: 17% (15 aa)

LALDWAGLLR----HKAEFVPQLE----AEDDTSYFD--TRSERYRHLGSEDDETNDEESSTEIPQ------------FSSCSHRF
  .|| .|..     .. |.|..      . |||.||    .|  .       .|.|.. .... .            |   . .|
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

PDZ MAST3.AA PDZ 980-1060 25 3.7e-17 64.25 SMART 1-80 (80) Show / Hide
Range on Protein: 980-1060
Range on HMM: 1-80/80
Sequence Identity: 25% (24 aa)

KKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAG------LRAGDLITHING-ESVLGLVHMDVVELLLKSGN-----KISLRTTALE
. .|||..              .... ||..|.||  ||      ||.|| |. .|| ..| .. | ..|..| ..|.     |..|     .
GGLGFSIVG-------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG

PDZ MAST3.AA PDZ 1007-1057 25 1e-08 32.45 Pfam 33-86 (86) Show / Hide
Range on Protein: 1007-1057
Range on HMM: 33-86/86
Sequence Identity: 25% (14 aa)

SVEDG-SPAQEAG-LRAGDLITHINGESVLGLVHMDVVELLLKSGN-KISLRTT
.|  | ..|. .| ...|| |. |||... .. |...|... .|.. ...|   
EVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ