Gene MYO3B (Human)

MYO3B

Species: Human
Alias: MYO3B
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 2q31.1,

Classification

Group: STE
Family: STE20
Subfamily: NinaC

Sequence

Name Sequence Type Origin Length Description Download
MYO3B.NA RNA Sugen Kinome 5529 None Fasta, JSON
MYO3B.AA Protein Sugen Kinome 1341 None Fasta, JSON
MYO3B.kin_dom Protein Kinase Domain Sugen Kinome 267 None Fasta, JSON

Protein domain

Protein domains of MYO3B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MYO3B.AA NinaC 27-293 74 1.4e-228 765.64 In-house 1-267 (267) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-267/267
Sequence Identity: 74% (198 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQ
|||.|||||||||||.||.||..|..|||||.....|.|||||||||||.....|||||.||||.||.|.|.|.|||.|.|.|||||||..|||||.||.
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

RLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITA
|..|..|.|||..|..||||||.|..||||||||||||||||||||.||||||||.|||.||||.||||.|||||||||.||||..||||||||||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
|||||||||..||||....|||||||||||.|||.||.|||.||||||.||.|.||...|.|.||||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase MYO3B.AA STE20 27-293 48 2e-156 525.95 In-house 1-288 (288) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-288/288
Sequence Identity: 48% (141 aa)

WEIIETIGKGTYGKVYKVTNKRDGSL----AAVKILDPVS-----DMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTEL
.|..| ||.|.||||||...|. | .    .|.|...  .     |. |.|. |..|.. .  |||.||.|| ..| |.| . .||.| |.|.|||.|..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC-DDELWIVMEYCGGGSLTDI

VKGLLRCGQ-----RLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTS----TRL-RRNTSVGTPFWMAPEVIACEQ
.|. ..||.     ...|. |.||....| ||..||.|.|||||.|..|||||..| |||.||||.||||.    |.  .||| ||||.|||||||.|..
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

QYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIP--RNPPPTLLH--PEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
..|. || .||.|||||||||. .| ||.|||||.. .|.||  .|||||| .  |.||  ||..|...|| || | ||....|| ||||
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MYO3B.AA STE 27-293 35 2e-125 422.99 In-house 1-359 (359) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-359/359
Sequence Identity: 35% (129 aa)

WEIIETIGKGTYGKVYKVTNKR---------------DGSLAAVKILDPVS------------------DMDEEIEAEYNILQFLPN-HPNVVKFYGMFY
||.|| ||||..|.|||  |.                 | . |.|...  .                  .  ..|. | .|.. . . |||.||.||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KADHC--VGGQLWLVLELCNGGSVTELVKGLLRCGQRLD----------EAMISYILYGALLG-LQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSA
| .|.   ...||...|...|||.....|    ||..|.          |  |.||..  | | |..||...|||||.|. ||||     |||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTS---------------TRL-RRNTSVGTPFWMAPEVIACEQQY-DSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRN-----------
|||.               |.  .||| |||| ||||||| ...|  |. ||..||.||||.|.||. .| ||..|||| . .| ||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPTLLH-----------------PEKWCEEFNHFISQCLIKDFERRPSVTHLLD--HPFI
    |||.| .                 |.|| .||..||..||.|| . ||... ||   ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MYO3B.AA MSN 27-293 52 5.1e-115 381.31 In-house 1-265 (265) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-265/265
Sequence Identity: 52% (140 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKAD-HCVGGQLWLVLELCNGGSVTELVKGLLRCG
.|..|..|.||||.|||   .. |.|||.|..|   | .|||  | |.|.   .| |.. .|| | |        |||.|.|.|  ||||.|||     |
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVK--MTKG

QRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGIT
| | | .| ||    | ||.||| ...||||.|| |.||| .  ||||||||||||  |  |||| .|||.|||||||||. . | .|| | |.||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

AIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
|||. .|.||| ||||.. || |||||||.|   .||   |..|. .||||... ||.  ..| ||||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase MYO3B.AA MST 27-293 47 9.20000000001e-113 359.77 In-house 1-254 (254) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-254/254
Sequence Identity: 47% (127 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMD-EEIEAEYNILQFLPNHPNVVKFYGMFY--KADHCVGGQLWLVLELCNGGSVTELVKGLLR
 .|.| .| | ||.||| ..| .|.. |.|.. || . | .||. | .|.|   . ...||.|| ..  |  ||     |.| | |..|||  ..|    
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMV-PV-NEDLQEIIKEISIMQQC-KSKYIVKYYGSYFDAKNNHC-----WIVMEYCGMGSVCDIMK---I

CGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLG
 .. | |. |. |||..|.||| ||.|..|||| |  |||| .||  || |||||.||| |   ||| .|||.|||||||       . ||   | ||||
TQRTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLG

ITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
|||||.  | ||..| ||.  .|.|| .||||.  ||.|  ||| |...||.|. | |.. . || ||||
ITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase MYO3B.AA YSK 27-293 43 2.8e-99 299.61 In-house 1-257 (257) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-257/257
Sequence Identity: 43% (118 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMD--EEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRC
. . | ||.| .| |||  ..| .   |.||.|  .. |  | |  | ..|  .    .. |.|| . |     .  || . | | |||.  | |     
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLK-----DTKLWIIMEYCGGGSCLDLMKPKY-V

GQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGI
|| .||  |. ||   |.||  || .| ||||.|  |.||. .| ||| ||||..|.| | ..||| ||||.||||||| .|    |.||.  |.|||||
GQ-FDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEV---SYYDFKADIWSLGI

TAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
||.|.  | ||. |.|| . .| || |.||.|   ...   |  |.  || || | |||   || | ||
TAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase MYO3B.AA SLK 27-293 40 2.1e-89 301.81 In-house 1-259 (259) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-259/259
Sequence Identity: 40% (108 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMD-EEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCG
||||  .| | .|||||  .|  . .|| |...  .. . |.   | .||  .  |||.|| |. .|  .     .||...| |.|| | ..   ..  .
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYYYDN-----KLWMMIEFCDGGAVDNI---MVELE

QRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGIT
. | |  | |. .  . .|..||.|..||||.|  |||.| .|.|.| ||||||....|. .| | .|||.||||||..||   |  || . |.||||||
HPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGIT

AIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
 ||. ...||  .| |.. |.|| .  ||||. | .| .||. |. .|| || . |..  .|..|...
LIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase MYO3B.AA S_TKc 27-293 32 2.2e-88 300.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNG--GSVTELVKGLLR-
.||...||||..|||||...|..| . |.||..      | |. | .||.   .|||.||.|..|.       . |..|.|.|.|  |.. .. |   | 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRH

-CGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDA-RCDVWS
  .....| .. ...|  ...|...|...|||||.|  ||||..   .|. |||...||       .| .|||..|||||.        .|.  .||.||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWWS

LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLD-------HPFI
.|.. .|.  | ||      ....||. .             .|. .||..|| || |.||..  .|        ||..
CGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MYO3B.AA KHS 27-293 40 3e-84 283.27 In-house 1-258 (258) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-258/258
Sequence Identity: 40% (111 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKI--LDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRC
.|..  .| |||| |||  ... ..|||||.  ..|  |. . |  |  ...    |||.| ..| . . |     .||...| | |||. .    . . 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDF-AVIQQEIMMMKDC-RHPNIVAYFGSYLRRD-----KLWICMEYCGGGSLQD----IYHV

GQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGI
   | |  |.|.   .| ||..||..  .|||.|| ||||| .| ||| |||||||.| |  .|   .|||.|||||| | |..    |.  ||.|..||
TGPLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK--GGYNQLCDIWAVGI

TAIELGDGDPPLFDMHPVKTLFKIPRNP--PPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
|||||..  ||.||.||.. || . .    ||.|   .|| . | ||. ..|.|.  .||. ..|| |||.
TAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase MYO3B.AA Pkinase 27-293 28 7.1e-80 276.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEA-----EYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGG----SVTEL
..|...||.|..|.||| ..| .| . ||||.. ... ... ..     |  |.. | ||||.|..|..|.      .. ...|.|.|.||    .  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

VKGLLRCGQRL--DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGV----KLVDFGVSAQL-TSTRLRRNTSVGTPFWMAPEVIACEQQYD
...  . . ..  .|  .  ..|  | ||...|...|||||.|  |||.  .| .    |. |||...|. .      .| .|||..||||||      .
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GG

SSYDARCDVWSLGITAIELGDGDPPLFDM----HPVKTLFKIPRNPPPTLLHPEKWC---------------------EEFNHFISQCLIKDFERRPSVT
. |. ..|.||.|.. .|.  | ||  .     . .  ...| |. .| |  .. |                      ||. .||. || || ..||. .
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

HLLDHPFI
..| ||..
QILQHPWF
Kinase MYO3B.AA PAKL 27-293 40 7.8e-80 271.53 In-house 1-256 (256) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-256/256
Sequence Identity: 40% (110 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDM-D-EEIEAEYNILQFLPNHPNVVKFYGMFYKA-DHCVGGQLWLVLELCNGGSVTELVKGLLR
 |. |  | | || |||.. |  .   |.| . ..    . ..|| | .||    . ||.|  .|      .|     .|  .. |  ||.  . .    
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVI-EIKESNEIKDIEKEIQILK-KCKCPNIVSYFGSIQQKLNH-----YWILMDYCSLGSINDMME---S

CGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLR--RNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS
|.  |.|. || ||  .|.||  ||   |||||.|  ||||.  . ||. ||||| || .. ..   |  .|||.|||||.|         |.  ||.||
CCKTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDE-YDGQANQMIGTPYWMAPEIINKQN-----YNNKCDIWS

LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
|||||||. || ||. || | . .  ||. ||||.  | .|  .|| |. ||. || | |.|.  ||.||||
LGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase MYO3B.AA PAKA 27-293 37 1.1e-78 267.75 In-house 1-260 (260) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-260/260
Sequence Identity: 37% (102 aa)

WEIIETIGKGTYGKVYKVTNKRDGSL--AAVKILD-PVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLR
 . .| ||.|  |.||..||.. ..    |.| ..    .. | |  |  ..    .|.|.|...  .   |..    ||.|.|  .||. |....   .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKEC-KHKNIVNYIDSYLV-DDE----LWVVMEYMEGGCLTDVITQCCN

CGQR-LDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSL
     .||..|.|..   | ||. .|.. .||||.|  |||| ..| ||. |||  ||||  ...||| |||| |||||||   |     ||   |.|||
IQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDIWSL

GITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
|| |||. .| ||  .. |.. .. |  |  | ...|.|| .||. | ..|| .| .||.|.. || |||.
GIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MYO3B.AA Pkinase_Tyr 27-293 25 3.5e-24 82.53 Pfam 1-270 (270) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-270/270
Sequence Identity: 25% (72 aa)

WEIIETIGKGTYGKVYKVTNK----RDGSLAAVKILDPVSDMD----EEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQ--LWLVLELCNGGSVTE
 ......|.| .|.||| | |     ..   |||.| . .. .    |.  .| .|.  |..|||.|..||  .    . |..  ...|.|.. .|    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT----DQGEPNQIYIVMEYMPHG---D

LVKGLLRC---GQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQL-----TSTRLRRNTSVGTPFWMAPEVIACEQQ
| . | .    .|.|.  ..  . .    |...|.....||||.   |.|.| .. ||  ||| .  .       .| | ..     .|||||.|.    
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGK-

YDSSYDARCDVWSLGITAIELGD-GDPP-LFDMHPVKTLFKI-PRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFI
    .    |||| |..  |.   |. |   .| .   . .|  ..    .  ||. ..|  . . ||  .| |.||. . .  | ..
----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase MYO3B.AA TyrKc 27-293 24 1.3e-15 29.87 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-293
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFL-PNHPNVVKFYGMFYKADHCVG--------GQLWLVLELCNGGSVTEL
 . ....| | .|.||| | |      ||| | . .   |..  | .|.  | ..|||.|..||       |.         ..|..|.|.. .|.   |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGV------CTQQGRNFMYIEPLMIVMEYMPHGD---L

VKGLLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTST--------RLRRNTSVGTP-----FWMAPEVIA
 . | ... .|  .   .. . .  | ..|| ...||||    |.|.. .. ||  ||| |  ...           |  .. |.       |||||.| 
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

CEQQYDSSYDARCDVWSLGITAIEL-GDGDPPLFD-----MHPVKTLFKIPRN----PPPTLLHPEKW----C-EEFNHFISQCLIKDFERRPSVTHLLD
     .. .    |||| |..  |.  .|..|  .     | .   . .. .     .||  .  .      | .|    ..||   | | ||. . .  
----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--

HPFI
| ..
HECF
MYSc MYO3B.AA MYSc 337-1059 33 3.3e-264 884.94 SMART 1-771 (771) Show / Hide 
Range on Protein: 337-1059
Range on HMM: 1-771/771
Sequence Identity: 33% (271 aa)

EDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNL-SIYSPQFSRLYH------GVKRASNPPHIFASADAAYQCMVTLSKD
    |    ||...|. | |....| |.|||.  .|||| |...||.||...|  ||.|.. ..|.      | .|  .|||||| ||.||..| . ...
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN

QCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREK
|||.||||||.||||....| |.|....  . ... ..||| | . |||||  |  |.|||||||| |. |  .| . || |. ||||||||..|.  | 
QCIIISGESGAGKTENTKKIMQYLAAVSG-QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGER

NFHIFYYIYAGLHHQKKLSDFRLPE----EKPPRYIAD------------ETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIG
|.||||...||.  .  .. |.| .     .  .|..             .. .|  .|  .| ...  | ... .|..||...|.....||.|.|| .|
NYHIFYQLCAGAS-EEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVD-GIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLG

NIEFAAISS--QHQTDKSE-VPNAEALQNAASVLCISPEELQEALTSHCVVTRGE---TIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDE
||||... .    |.  || |.. |.||||.. | ..||.|...||.  ..|..|   .|.....|  |.. |||..||.|.|||.|||.|||. .    
NIEFEQGRNQYDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM----

NICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYE--DNRPLLDMFLQK---PLGLLALLDEESRF-
          .|.|||.|||.|..|||||.||| .||. |..||.|.| ||| |||.|||.  ....   || | .|   .|   |.|...|||||..| 
------HNYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFH

--PQATDQTLVDKFEDN-----LRCKYFWRP------------KGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTK
  |..||||...|   .     .    ....            .  . .|.|.||||.| |.. | ||||.|||..|.. ....| |....|||.   ..
AQPKGTDQTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQ

T------------GNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETT----NMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREAL
|            ....  .. . ... .                               . .||.. |. .| .|....   .||..||||||. . . 
TSQTPQEKSSQGKNKSRRKKR-M-MQM-K------------------------KTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPW

QFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTP---------LASKESCVAILEKSR---------LDHWVLGKTKVFLK-Y
.| ...|| |||  |.||.. ||| |...|. ..||..||. |..  ....            |..|.|||...           | . .||||||.. .
DFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPYQEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNP

YHVEQLNLLLRE
.... |  . ..
GQLFHLEEMRER
Myosin_head MYO3B.AA Myosin_head 582-1046 30 1e-142 485.24 Pfam 249-765 (765) Show / Hide 
Range on Protein: 582-1046
Range on HMM: 249-765/765
Sequence Identity: 30% (163 aa)

FEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIE-FAAISSQHQTDKSEVPNAEA-LQNAASVLCISPEELQEALTSHCVVTR----GETIIRANTVDR
|. ..  ..|||||..| .|..||.|.||..||.. |.   .. |    .|.. |. ...... ....|||.. .|..  ..|.     |.. .. ....
FQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA---VVDDTEEICEIICELMGVDPEEFEKWLCYRRIKTGGGKRREWVTKPQNCEQ

AADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAG-------------------------------GGMNVGILDIFGFENF-QRNSFEQLCINIAN
|.. |||..||.|.|.| |||||||      ..||.                                  .  .|.|||.||| | ..|||||.||| .|
AMYARDALAKAIYSRMFDWIVNRIN------QAICHKTQNTDDSDGQAAQWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCEKNSFEQFCINYCN

EQIQYYFNQHVFALEQMEYQNEGIDAVPVEY-EDNRPLLDMFLQK--PLGLLALLDEESRFPQATDQTL----VDKF-EDNLRCKYF-WRP-K------G
|. |..||.|.| ||| ||..|||.  ...|  || |  |  . |  |.|.|.|||||..||.|||||.    .. . . ..| . |  .| .      .
EKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCD-LIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPR-LHFAQKPGRFYKRHRQ

VELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSEN-KLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPEETTNM
 . .| | ||||.| |...| ||||.|.|. |.. ... | . ...|.||  . . .  . |         .  ..| .  |..  ..   . .   ...
GNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELFPDWEWAEWAHMQ-------IDFEADFHEEEFKRRYNRNGCQKGKQGKKKW

KRQTVASYFRYSLMDLLSKMVVG---QPHFVRCIKPNDDREALQFSRERVLAQLRSTGILE-TVSIRRQGYSHRILFEEFVKRYYYLAFTA------HQT
. |||.. |. ..  |.  .       ||.|||||||. . . ||....|| |||  |.|| .. |.|.|...|... ||..||. |.. .        .
FMQTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQRYRILCPKTWWSWIWPEW

PLASKESCVAILEKS---RL--DHWVLGKTKVFLK
  ..|. | .||..     .  . . .||||.|..
NGDTKQGCEKILQHLSWGNMDKEEYQFGKTKIFFR
Myosin_head MYO3B.AA Myosin_head 345-552 43 1.9e-89 308.27 Pfam 1-217 (765) Show / Hide 
Range on Protein: 345-552
Range on HMM: 1-217/765
Sequence Identity: 43% (95 aa)

EDDLVNLEVLDEDTIIHQLQKRYA-DLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKT
 .|.|.|. | |....| |.|||.  .|||||.|...|..||...| ||.. .   |.| .|  .|||||| ||.||. |..  ..|||.|.|||| |||
VEDMVMLTYLNEPSVLHNLKKRYMTGDLIYTYSGHFCISVNPYKQLPIYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAGKT

ESAHLIVQHLTFLGKANN--Q--TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVV----MGARISEYLLEKSRVIKQAAREKNFHIFY
|.. .. |......  |.  .  .. ..||| | . |||||  |  |.||||||||.|. |. || .     |..|. ||||||||..|.. | ||||||
ENTKYVMQYFASVSGSNPGVNMGRVEQQILQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHIFY

YIYAGLHHQKKLSDFRL
...||.  |. . ...|
QLLAGASQQEEKKELHL
IQ MYO3B.AA IQ 1059-1081 30 0.13226 7.42 SMART 1-23 (23) Show / Hide 
Range on Protein: 1059-1081
Range on HMM: 1-23/23
Sequence Identity: 30% (7 aa)

EVIGRVVVLQAYTKGWLGARRYK
..   ....||.  |.|  .|||
RMHRAAIIIQAWWRGYLARKRYK
IQ MYO3B.AA IQ 1061-1081 23 0.132389 9.07 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1061-1081
Range on HMM: 1-21/21
Sequence Identity: 23% (5 aa)

IGRVVVLQAYTKGWLGARRYK
   ....||. .|.|  ..|.
HRAAIKIQAWWRGYLARKHYR
IQ MYO3B.AA IQ 1088-1108 47 8.2e-08 29.17 Pfam 1-21 (21) Show / Hide 
Range on Protein: 1088-1108
Range on HMM: 1-21/21
Sequence Identity: 47% (10 aa)

EKGAIAIQSAWRGYDARRKFK
.. || ||..|||| ||....
HRAAIKIQAWWRGYLARKHYR
IQ MYO3B.AA IQ 1086-1108 47 1.1e-07 32.78 SMART 1-23 (23) Show / Hide 
Range on Protein: 1086-1108
Range on HMM: 1-23/23
Sequence Identity: 47% (11 aa)

KREKGAIAIQSAWRGYDARRKFK
.... || ||..|||| ||...|
RMHRAAIIIQAWWRGYLARKRYK