PASK

Species: Human
Alias: PASK, PASKIN, DKFZp686P2031, DKFZP434O051, STK37, KIAA0135
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 2q37.3 ,

Classification

Group: CAMK
Family: CAMKL
Subfamily: PASK

Sequence

Name Sequence Type Origin Length Description Download
PASK.NA RNA Sugen Kinome 4530 None Fasta, JSON
PASK.AA Protein Sugen Kinome 1323 None Fasta, JSON
PASK.kin_dom Protein Kinase Domain Sugen Kinome 253 None Fasta, JSON

Protein domain

Protein domains of PASK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PAS PASK.AA PAS 121-188 22 1.5e-10 42.33 SMART 1-68 (68) Show / Hide
Range on Protein: 121-188
Range on HMM: 1-68/68
Sequence Identity: 22% (16 aa)

PLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDS--DVVEALSEEHME
. . | . | . .|. .|  . .|. .|..|| ..||| ..|||| ..... . |   . ...  .....
ERYRAILENMPDGIWVWD-HDGRITYWNPAACQMFGYSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ

PAS PASK.AA PAS 133-235 15 4.3e-05 19.48 Pfam 14-120 (120) Show / Hide
Range on Protein: 133-235
Range on HMM: 14-120/120
Sequence Identity: 15% (17 aa)

AIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSD----VVEALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQE--RRL
.|| .| . ..|| .|..|. ..|.| ....|. |  ..   |..    ....| .   .     ..    ..    | |. ... |... .| .  ...
PIFVWD-EDGWILYWNRAAERMFGWSREEVMGKMLYDLIHHDDHRCCLEFHDQLWQCMQQGEE-RMFEITFRTPGQHRDGRPRWCEVRWCPYRDPGGEIH

CCVVVLEPV
. .... ..
GFCCFMHDI

PAS PASK.AA PAS 335-402 20 0.000228 21.76 SMART 1-68 (68) Show / Hide
Range on Protein: 335-402
Range on HMM: 1-68/68
Sequence Identity: 20% (14 aa)

YRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTELLGKNITFLIPGFYS--YMDLAYNSSLQL
 | .  .  .  |.. . .||.|  .|....  .  | . ||.|.... ||.  .    . ..   .|| 
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFG-YSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ

Kinase PASK.AA PASK 999-1251 64 1.2e-210 665.06 In-house 1-260 (260) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-260/260
Sequence Identity: 64% (167 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVE---HANIIKVLDIFENQGFFQLVMEKHGSG--LDLFAF
|......|.||.|.||.....|....||||||.||||.||||..|.|.|...|||.|.....   |.||.||||.|||..|.||||||||||  .|||.|
YTSIQQMGEGAYGYVWMCIHNECRYIVVVKFIFKEKVCEDCWVRDRKCGCIPLEIHIMQTLNKNPHENIVKVLDFFENDDFYQLVMEKHGSGGCMDLFDF

IDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTL
|||||..||.||||||||.|.||.||. ..|.||||||||..|.|.|||||||||||||.||||.|||||||||||||||||||||||||.|||.|||||
IDRHPNMDEHLASYIFRQVVAAVKYLHEQGIVHRDIKDENVIIDEHFTIKLIDFGSAAYMERGKFFYTFCGTIEYCAPEVLMGNPYRGPEQEMWALGVTL

YTLVFEENPFCELEETVEAAIHPP--YLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV
|||.|.|||||..|||.||.||.|  ..||.|.|||....|...||.|.|.....||||.
YTLMFKENPFCNIEETLEAEIHFPNAEHVSEECMSLIKSMLNRCPEKRCTMHQIITDPWL

Kinase PASK.AA CAMKL 999-1251 32 8.99999999999e-111 354.76 In-house 1-297 (297) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-297/297
Sequence Identity: 32% (97 aa)

YSTMSPLGSGAFGFVWTAVD-KEKNKEVVVKFIKKEKVLEDCWIEDPKLG-------KVTLEIAILSRVE---HANIIKVLDIFENQGF------FQLVM
|     || |.|| |  |.. .  ...| .|.|.|.|  .|.|... |.|       ... ||.|....    | |||| ....|.. .      ..|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EKHGSG-LDLFAFIDRHPR----LDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDF--TIKLIDFGSAAYLER-----GKLFYTFCGTIEYC
| ...| .||| .|..|..    ..|. |  .|||.|||| |.  ..|.||||| ||| . |.   .||.|||| ... ..     |... ||||. .|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLMG--NPYRGPELEMWSLGVTLYTLVFEENPFC--------------ELEETVEAAIH-PPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV
|||.. |   ||.||.  .||.||.||..|. . ||               .... .      ..| || .. .| ...||. ||.| |.. .. .||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase PASK.AA CAMK 1004-1251 23 3e-92 297.51 In-house 1-425 (425) Show / Hide
Range on Protein: 1004-1251
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

PLGSGAFGFVWTAVDKEKN------------KEVVVKFIKKEKVLED--------------------CWIEDPKLGKVTLEIAILSR-------VEHANI
 ||.|.|| |  ...|. .            ..| .|.|.|.|. ..                    ||... .. .|  ||.|...       . | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKVLDIFE--------NQGF------------FQLVM---EKHGSG-L--DLFAFIDRHPR---------------LDEPLASYIFRQLVSAVGYLRLKD
|| ....|        |. .            . .||   |    | |  ||| .| .|..               ..|  |...|||..||| |.  ..
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKDENIVIAED-----------------FTIKLIDFGSAAYLER------------------------GKLFYTFCGTIEYCA-PEVLMG-----
|.|||.| ||| . ..                 ..||.|||| |.....                        |....||||| ||.| |||| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------NPYRGPELEMWSLGVTLYTLVFEENPFC---------------ELEETVE----AAIH-PPYL---------------VSKE--------LM
        .|| ||.  |||.|| ||...  . ||                ...|. |    .  . ||.                .|.|         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLVSGLLQPVPERRTTLEKLVTDPWV
.|....||. ||.| |.|    .||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase PASK.AA S_TKc 999-1251 30 5.1e-76 259.77 SMART 1-231 (231) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-231/231
Sequence Identity: 30% (81 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGS-GLDLFAFIDRH
|  . ..|.|||| |. ...|. ...| .| ||                ..  ||.||..  | ||.| .|.|.. ... .|||  .  . ||| .|...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

PR------LDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGV
.|      ..|  | ....|...|. |.  . |||||.| ||| . |  .||..|||.|. |      .||||| .|.|||||   .| ...  .||.|.
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

TLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVT-------DPWV
.|| ..  . ||.    .... ..     |.|. ......||  ||.| |  .. .       .||.
ILYEMLCGYPPFP----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase PASK.AA Pkinase 999-1251 29 7.4e-72 249.84 Pfam 1-293 (293) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGL---DLFAFID
| . ...|||.|| |. ...|  .|.|.|| |||..  ....... .|     ||.|. |. | ||.. .|.||. .   .||| .. ||   |||..| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

--RHPRL--DEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTI----KLIDFGSAAY--LERGKLFYTFCGTIEYCAPEVLMGNPYRGPELE
  || ..  .|  .  ...|..... |.  . |||||.| ||| | .. .|    |..|||.|.   . ..  ..|||||..|.||||..|..| ||.  
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

MWSLGVTLYTLVFEENPFCEL--------EETVEAAIHPPYLVS-------------------------KELMSLVSGLLQPVPERRTTLEKLVTDPWV
|||.|..|| ... . ||..          . ..   .||.  .                         .|. ......|.. |..| | | .. .||.
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase PASK.AA NuaK 999-1203 40 1.4e-70 184.55 In-house 1-199 (252) Show / Hide
Range on Protein: 999-1203
Range on HMM: 1-199/252
Sequence Identity: 40% (83 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPK-LGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRH
|     ||.| .| |  |....  .|| .| |||.|      |||.. . ..  || |.| ..| .||..  .|||.    .|||   || .|. .|.. 
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCK------IEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVME-YASGGELYDYISEC

PRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLV
 .| |  |  .||| |||| |  .  |.||| | |||   ..  .|  |||   | . .|.  ||||   |  ||.  | ||.|||   ||||| |||.|
KSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMV

FEENPF
.   ||
YGTMPF

Kinase PASK.AA MARK 999-1251 37 1.4e-64 210.03 In-house 1-262 (262) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-262/262
Sequence Identity: 37% (101 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFE--NQGF-FQLVMEKHGSGLDLFAFID
|     .| |... |  |..|  ...| .|...|.|  . .|..     .|  ||.|.....| |||| ....|  . .  . |.|| . || .|. .| 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMK-----NVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIME-YASGGELYDYIK

RH--PRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDF--TIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGV
 |   || |..|  ||||.|||| |.  |.|.||||| ||| | |.    ||.|||| ..  . |..  ||||| .|.|||.. . || ||.  .|||||
AHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV

TLYTLVFEENPF---C----ELEETVEAAIHP-PYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV
 ||..|    ||   .    ||.. . .   . |. ||||. .|.. ||.. ||.| |.| .. .||.
VLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase PASK.AA PIM 999-1251 33 2.6e-49 167.31 In-house 1-260 (260) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-260/260
Sequence Identity: 33% (88 aa)

YSTMSPLGSGAFGFVWTAVDKEKN-KEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHA----NIIKVLDIFENQGFFQLVMEKHGSGLDLFAF
|.  . ||.| || |. ..    |   | .|...||.|..  | . .   .| .|.. | ... .     .|. || ||..  | .|||      ||| |
YQVGPELGRGGFGTVYAGHRICDNQQPVAIKHVEKERVKD--WGMLCDGQQVPMEVCMLWKCSSIGGHHGVIRLLDWFERPDGFMIVMERPYPCQDLFDF

IDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFT---IKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLG
|  .  |.|...  .|.| . .|     . ..|||||||||.|  |     .||||||..|.|..      | ||  || ||      | | |   ||||
ITEQGPLNEDMCRFFFWQVWATVHHCHQCHVLHRDIKDENILI--DMNTGEVKLIDFGAGAMLHD-TVYTDFDGTRVYCPPEWIRHHRYHGREATVWSLG

VTLYTLVFEENPFCELEETVE----AAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV
| || .|    ||   .| ..    . .| .  ||.|.  |..  |.. |  | .||    .||.
VLLYDMVCGDIPFENDQEICRAHLLGELHFRQHVSHECCQLIRWCLTFKPSHRCSLEQILNHPWM

Kinase PASK.AA Ciliate-E2 999-1251 24 2e-45 153.92 In-house 1-365 (365) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEV-----------------VVKFIKKEKVLEDCWIEDPKLGKVTL-EIA----------ILSRVEHANIIKVLDI
|     .|.|.|| |. . .....|..                 | ..|.  |...   ||  |  .  . ||           ||... | ||||  . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NQGFFQLVMEKHGSGLDLFAFID------------RHPRLDEPLASYIFRQLVS---------------AVGYLRLKD-IIHRDIKDENIVIAEDF
|.  ..  . ||||   .| ||| .|                ...|  ..||..|...               |. ||  |  ||||||| |||..    
FQEKDDNNIYLVMEYC-QGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

TIKLIDFGSA-----------------AYLERG----------------KLFYTFCGTIEYCAPEVLMGNPY--------RGPELEMWSLGVTLYTLVFE
 ||.|||| .                  |.. .                 .|.|.||| .| |||.|.| .|         . .  .|||||.|| ..| 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

ENPFCELEETVEAAIHPPYL------------------VSKELMSLVSG----LLQPVPERRTT-LEKLVTDPWV
. ||  ...  .  |  |                    .|.| . | .     .||  || | |  |..   || 
KPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase PASK.AA MELK 999-1251 31 3.6e-44 148.68 In-house 1-254 (254) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-254/254
Sequence Identity: 31% (82 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHP
|     .|.| |. |  |.    |. | .| . |... .|       | .|  |.  |  ..| .| ..  . | .  . .||| . .| ..| .| |. 
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD-------LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVME-YCPGGEMFDYIIRQD

RLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYT----FCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLY
||.|  .  .|||.|||. |.  .   |||.| ||... ||. .||||||  |   .|.  |      ||   | |||.. |  | | | ..||.|. ||
RLEEEETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLY

TLVFEENPFCE------LEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV
.|.    || .          .    . |  .| |   |.  .|| .|..|  . .|.  |||
VLMCGFLPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase PASK.AA QIK 999-1251 28 6e-44 152.32 In-house 1-272 (272) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-272/272
Sequence Identity: 28% (79 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHP
|     .| | |. |  |  .   ..| .| | |..  |.       | |.  |..|. . .| .||| ... | .    .|.|   |. ..|  .  | 
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE------NLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTE-YCSNGEMFDYLCKHG

R--------------------LDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNP
|                    . |. |  .| |..||| |.  . |.|||.| ||| . ..  ||..|||   . . |.|  |.||.  | |||.. |. 
RKGVKMVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKE

YRGPELEMWSLGVTLYTLVFEENPFCELEE------TVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWV
| ||..  ||.|| || ||    ||            ..     |. .|... .|.   |   ||.| | .  .  .| 
YDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase PASK.AA Ciliate-E2-Unclassified 999-1251 22 9.5e-44 149.62 In-house 1-352 (352) Show / Hide
Range on Protein: 999-1251
Range on HMM: 1-352/352
Sequence Identity: 22% (78 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEV-VVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSR------------------VEHANIIKVLDIFENQGFFQL
|     .|.|.|| |. ...|... .. . | .|| ..  .. |.  .  ..  .... ..                    | .|.| ...|...  . .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEKHGSGLDLFAFIDRHP----------------RLDEPLAS-----YIFRQLVSAVGYLRLKD-IIHRDIKDENIVIAED---FTIKLIDFGSAAYLE
|||.   |  ..   .|.                 ...|  |.     ..|.|....  ||  |  ||||||| |||.. ..   . ||.||||.. ...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------RGKLFYTFCGTIEYC----APEVLMGNPYRGP---ELEMWSLGVTLYTLVFEENPF-CELEET----------------VEAAI
                . ....|||||..|     |||||.|. | ..   .  .||||| || ..| . || .. .|                 ..  |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

H---------PP----YLVSKELMSLVS----GLLQPVPERRTTLEKLVTDPWV
.         |.    . .|.|   ...     .|.  |. | |.|..   || 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase PASK.AA TyrKc 999-1249 20 1.8e-10 -53.18 SMART 1-280 (280) Show / Hide
Range on Protein: 999-1249
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRV--EHANIIKVLDIFENQ-------GFFQLVMEKHGSGLD
 .    ||.|||| |. .. |    .| || .|...           .     |. |....  .| ||.. . .   |       .   .||| . .. |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVME-YMPHGD

LFAFI-DRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERG------KLFYTF----CGT----IEYCAPEVL
|  .. ...|.|  .   ..  |  .   ||  | .||||.   |. ..|..|.|  ||| . ... .      |  |.     .|     |  .|||..
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

MGNPYRGPELEM--------WSLGVTLY-TLVFEENPFCE----------LEETVEAA---IHPPYL-------VSKELMSLVSGLLQPVPERRTTLEKL
          .         || ||...  . . . |  .          . | |..      ||.         ..|. .. .   .  || | | . .
---------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

VTDP
. . 
HECF

Kinase PASK.AA NuaK 1227-1251 32 0.000577 5.72 In-house 228-252 (252) Show / Hide
Range on Protein: 1227-1251
Range on HMM: 228-252/252
Sequence Identity: 32% (8 aa)

LVSGLLQPVPERRTTLEKLVTDPWV
|.  .|.  |.|| |..     .||
LIRWMLMVNPRRRATIYDICHHWWV