Gene PKACg (Human)

PKACg

Species: Human
Alias: KAPG, PRKACG, PKACg
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 9q13,

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
PKACg.NA RNA Sugen Kinome 1619 None Fasta, JSON
PKACg.AA Protein Sugen Kinome 351 None Fasta, JSON
PKACg.kin_dom Protein Kinase Domain Sugen Kinome 255 None Fasta, JSON

Protein domain

Protein domains of PKACg.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PKACg.AA PKA 44-298 65 3e-203 681.49 In-house 1-263 (263) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-263/263
Sequence Identity: 65% (171 aa)

FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLV-KLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEP
||...|||.||||||||.||...| .||||.|.||..|..|||||..|||.|||.|..||.| |....|.|..|||.||||||||||||.|...||||.|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

HACFYAA-QVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSK-GYNKAVDWWALGVLIYEMAVGFPPFY
||.|||| |.||| .||||...|.|||||||.|||..|....|||||||.|..|||||||||||||||||.|| |..|.|||||||.|||||..|.||||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

AD--QPIQIYEKIVSGRVRFPSKLSSDL---KHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
..  .|.||||||..|...||. ..||.   |.|...|||||||||.||..||| ||||||||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase PKACg.AA AGC 44-298 34 7.4e-190 496.34 In-house 1-395 (395) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-395/395
Sequence Identity: 34% (137 aa)

FERLRTLGMGSFGRVMLVRHQ------ETGGHYAMKILNKQK-VVKMK--QVEHILNE------------KRILQAID----------FPFLVK-LQFSF
|| |...| ||||.|.|||.        ||  ||||.|.|.. .|..|  .|||...|            ..||. ..           ||.|| | .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDNSY--LYLVMEYVP---------GG-EMFSRLQ---RVGRFSEPHACFYAAQ-------VVLAVQYLHS-LDLIHRD-LKPENLLIDQQGYLQVTDFG
.|...  ||.||||.|         || |.|..||   . |||.|..|.||||.       .|||..|||| .. |||| |||||.|.|..|..  ||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKRVKG-----------------------------------------------------RTWTLCG--TPEYLAPEIILSKGYNKAVDWWA--LGVLIY
..|....                                                     ||||.||  ||||.||||.    |.||.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMAVGFPPFYAD----------QPIQIYEKIV------SGRVRFP----------SKLSSDLKHLLRSLLQVDLTKRFGNLRN-----GVGDIKNHKWF
|| .| ||||.|          .| ....||       . .|.||          ...|...|.|.. ||..| .|| |...|     |. .||||.||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKACg.AA Akt 44-298 47 4e-130 418.2 In-house 1-264 (264) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-264/264
Sequence Identity: 47% (125 aa)

FERLRTLGMGSFGRVMLVRHQETGGHY-AMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEP
|. |. || ||||.|.||.   |.  | |||.| |.. ....||||.. |..||| ...||.|.| .|| .. .||.||.|..||| |. ||| .||||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

HACFYAAQVVLAVQYLHSLDLIHRD-LKPENLLIDQQGYLQVTDFGFAK-R-VKG--RTWTLCGTPEYLAPEIILSKGYNKAVDWWA-LGVLIYEMAVGF
 | ||.|...|| ..||| . | || |||||.|.|..|.. .|||| .|   .|   .| |.|||||||||||.. .|. ||||||. ||...|||  |.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYADQPIQIYEKIVSGRVRFP--SKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
||||...  | ..|| .. |.||  ...| . | |...||. | .|| |.  |.. .||.| ||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PKACg.AA SGK 44-298 41 4e-129 401.07 In-house 1-283 (283) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-283/283
Sequence Identity: 41% (119 aa)

FERLRTLGMGSFGRVMLVRHQET------------------GGHYAMKILNKQKVV-------KMKQVEHILNEK-RILQAIDFPFLVKLQFSFKDNSYL
|. | ..| ||||.|..|.| ..                  .  ||||.|.|| ..       | |.. ||. |.  ||. .  ||.|.| ..|    .|
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSK
|.||.|| |||||. ||| ..|.|. | ||||..|.|  ||||.| |.|||||||.| | ||..  |||| .|     .  | | ||||||||||... .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
.. ..|||| || . ||| .| ||||     | |..| ..  ..|   |.| ..|.  ||| | .|| |  ... ..|||| .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF
Kinase PKACg.AA AktR 44-298 42 2.6e-120 406.0 In-house 1-268 (268) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-268/268
Sequence Identity: 42% (114 aa)

FERLRTLGMGSFGRVMLVRHQ-ETGGHYAMKILNKQKVVKMKQVEHILNEKRILQ-AIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSE
|.... ||.| ||.|.||..  ...  ||||.. |.| .. .| .|...|. |..  ...||.||| ..|.....|...|||.||||.|. |.. ..|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PHACFYAAQVVLAVQYLHSL-DLIHRDLKPENLLIDQQGYLQVTDFGFAK----R-VKGRTWTLCGTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAV
  | ||.||..||..|||.  . | |||||||.|.|. |..  |||| .|    .    .. ..||||||.|||.|.  ||.||.|||||.|..|||| .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GFPPFYADQPIQIYEKIVSGR---VRFPSKLSSDLKHLLR-SLLQVDLTKRFGNLRNGVGDIKNHKWF
| ||||...  |...|| . .   . .||..|| .| |.   ||. . .|| |  .||  .||.|.||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKACg.AA RSK 47-298 41 2.4e-111 376.22 In-house 1-278 (278) Show / Hide 
Range on Protein: 47-298
Range on HMM: 1-278/278
Sequence Identity: 41% (116 aa)

LRTLGMGSFGRVMLVRHQ---ETGGHYAMKILNKQKVVKMKQ-VEHILNEKRILQAID-FPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGR---
|. || |..| | |.|      || .||||.|.| |.|. .  ..| . | .||...   ||.|.|  .|.....|||.|||..|||.| .||. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQ---QGYLQVTDFGFAKRV----KGRTWTLCGTPEYLAPEIIL----SKGYNKAVDWWALGV
|||  ||||.|..||||..||... ||||||||| | |.   .| . .|||||.|      ...| | |.| ||.|||..      .|..||.||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMAVGFPPFYA---DQPIQIYEKIVSGR--VRFP--SKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
|.||| .|.|||..   ... .| ..| .|.  ...|  ..|| . |.|.| .|..|  || |  .... .||.|.||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PKACg.AA S_TKc 44-298 39 7.1e-109 368.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-231/231
Sequence Identity: 39% (104 aa)

FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPG--GEMFSRLQRVGR---
.| ||..| |.||.|...|| .|| ..|.||..          |||..| .||.  . |..|||  .| | ..||.||||..|  |..|..... ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK-AVDWWALGVLIYEMAV
   |.| ||.||..|...|..|.||.  |||||||||.|.|.   . ..|||.|...     |.||||.|.|||..   ||.| ..|||..|...|||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGV--GDIKNHKWF
| |||.  |. ....||.          |...|...| .||.| .|| .         |||.| ||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKACg.AA PKG 44-298 43 3.4e-106 359.1 In-house 1-260 (260) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-260/260
Sequence Identity: 43% (112 aa)

FERLRTLGMGSFGRVMLVRHQETG-GHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEP
.... |||.| |||| ||. ..     .|.|...|. .|. .| ||| .||.|..  . .| |.|   |.|. |.|. ||   |||. . |   |.| ..
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

HACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
 . ||.| || |  |||.  .| ||||||||. |..||.   ||||||...  ..||| |||||| |||||| ||   .||.||||.|..|  .| ||| 
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

ADQPIQIYEKIVSG--RVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
.  |...|  | .|   . ||.| .   ... ..|     | | |...||..||| ||||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase PKACg.AA p70 44-298 36 5.8e-96 325.12 In-house 1-299 (299) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-299/299
Sequence Identity: 36% (108 aa)

FERLRTLGMGSFGRVMLVRHQE---TGGHYAMKILNKQKVVK-MKQVEHIL-------------------------NEKRILQAIDFPFLVKLQFSFKDN
||.|. || | .| |..|| .    ||  |||| | | |.|   |  .|                            |  || ..  ||...| ..|..|
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRV--KGRT-----------WTLCG
. |||. || .||| |  | | | . |  ||||.. ...| ..||... | ||||||| . .||| .  ||||  |    .|             .|.||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGR--VRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
|.|| ||||.. .|.|.|||||.||.|.| | .| ||| .. . .. .||  |.  .. | .|. . . |.. ||  . |.| |   . ..||. |..|
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase PKACg.AA Pkinase 44-298 31 1.4e-92 318.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHIL-NEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGG----EMFSRLQ--RV
....|..| ||||.| . .|. ||  .|.||..|..  . |...|.. .| .|.. .. |. |.|  .| |....|.||||..||    . |....  | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRF--SEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL----QVTDFGFA----KRVKGRTWTLCGTPEYLAPEIIL-SKGYNKAVDWWAL
|.|  || ...||. |.. ...|.||   |||||||||.|||..|..     ..|||.|       .. ..|.||||.|.|||.|. ...| ..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLIYEMAVGFPPFYAD------QPIQIYEKIVSGRVRFPSKLS---------------------SDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
|...|||. | |||. .       ..|....| .....|..  .                     ...|......|..| .|| .       .|..|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase PKACg.AA AGC-Unique 44-298 37 3e-92 312.77 In-house 1-270 (270) Show / Hide 
Range on Protein: 44-298
Range on HMM: 1-270/270
Sequence Identity: 37% (100 aa)

FERLRTLGMGSFGRVMLVRHQ---ETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFS
|| |. .| ||.||| .||      |.  ||||..||..  | ||. |   |..||  .. ||.... .||    .| ..|.|||||.||  .|. . | 
FEILKHIGVGSYGRVYAVRRKNGCDTEKFYAMKVMNKRDMSKHKQMVHHNTEWMILTTMHHPFFMRMHYSFQNKDHLFMCMDYVPGGDMFHHMQNAECFI

EPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKR-------VKG-----RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL
|  | || . |.  . |||. . |||| ||||.|||  | . .||.|  |        ...        |.|||..|.||||.. |.. |. |||. |..
EESAHFYICEVICSIHYLHENHIIHRDIKPENILIDNDGHIMITDYGLSKTGCDSVDAIQNGGEGGFATTFCGTRHYMAPEIHTEKKHGKSCDWWSVGIT

IYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWF
 ..|  .  || |      |.  . .| | |  ||.| . ..  |.  | ..| ||  .|  .|| |  |
YCDMRTDRSPFDASNRNDMYDSMIQKRPRMPMFLSPDEQDFVNKLIVRDPNQRLGNSPQGFEEIKSHDMF
Kinase PKACg.AA NDR 44-187 45 4e-67 205.84 In-house 1-149 (350) Show / Hide 
Range on Protein: 44-187
Range on HMM: 1-149/350
Sequence Identity: 45% (68 aa)

FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAID--FPFLVKLQFSFKDNSYLYLVMEYVPGGEMFS---RLQRVGR
|| ....| |.||.| |||. .||  |||||..|. ...  || |...|. |.   |   |. ||| .|| | .||||||||.||| | .   .|.. . 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFG
|.| .| || |  |.|. ..|..  ||||.||.|.|||..| .  ||||
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase PKACg.AA NDR 201-298 37 4.5e-36 108.28 In-house 243-350 (350) Show / Hide 
Range on Protein: 201-298
Range on HMM: 243-350/350
Sequence Identity: 37% (41 aa)

GTPEYLAPEIILS-KGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRF-----PSK----LSSDLKHLLRSLLQVDLTKRFGNLRNGVG
|||.|.|||...  .|||...||| ||.  ||| ||.|||..| |  ...|| . .  .       .    || . . |.| |. .|  .| |. ..|| 
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD

DIKNHKWF
.||.| .|
EIKSHPFF
Kinase PKACg.AA TyrKc 44-289 20 9.4e-16 32.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 44-289
Range on HMM: 1-280/280
Sequence Identity: 20% (58 aa)

FERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI--DFPFLVKLQFSFKDN-------SYLYLVMEYVPGGEMFSRLQ
 . ...|| | ||.|.. .        | | |.. .      .| ...| ||.  .  . | .|.|     .          |..||||.|.|   ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RVGR-FSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGR-------TWTLC----GTPE-----YLAPEIILSKGYN
. .. .. .. . .. |.    .||||  .|||||   | |.. ..   ..||| .. ..                  |.        .||| |  . ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWALGVLIYEMA-VGFPPFYA-----DQPIQIYEKIVSG-RVRFPSK--------LSSDLKHLLRSLLQVDLTKR--FGNLRNGV
 . | |. ||...|.   | .| .        .....|.. .| | . |           ....  . ..  . |  .|  | ...   
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase PKACg.AA Pkinase_Tyr 44-255 24 2.6e-11 38.91 Pfam 1-233 (270) Show / Hide 
Range on Protein: 44-255
Range on HMM: 1-233/270
Sequence Identity: 24% (58 aa)

FERLRTLGMGSFGRVMLVRHQ----ETGGHYAMKILNKQKVVKMKQ--VEHILNEKRILQAI-DFPFLVKLQ-FSF-KDNS-YLYLVMEYVPGGEMFSRL
 . ...|| |.||.|.. .      .|. . | |.| |.     .|   |  ..| .|.  . . | .|.|      .. . ..|.||||.|.| . . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

QR----VGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRV-------KGRTWTLCGTPEYLAPEIILSKGYNKAVDW
..     .... .. . ...|.  . .||.|  .|||||   | |.. ..   ..||| |. .       . |. .       .||| |  . .. . | 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDV

WALGVLIYEMAV-GFPP-FYADQPIQIYEKI-VSGR
|. |||..|.   |  | ..   . ..||.|  .|.
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase PKACg.AA S_TK_X 299-351 21 1.2e-10 42.63 SMART 1-79 (79) Show / Hide 
Range on Protein: 299-351
Range on HMM: 1-79/79
Sequence Identity: 21% (17 aa)

ATTSWIAIYE--KKVEAPFIPKYT----GPGDASNFD-DYEEEELRISINEK-------------------CAKEFSEF
. . | ..|   |..|.||.|| .    .|.|.|||| ...||. . .  ..                   ..  .  |
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF