Gene RIPK2 (Human)
RIPK2
Sequence
Protein domains of RIPK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | RIPK2.AA | RIPK | 24-290 | 42 | 8.70000000001e-154 | 517.2 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 24-290 Range on HMM: 1-290/290 Sequence Identity: 42% (122 aa) LSRGASGTVSSARHADWRVQVAVKH---LHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEF------LGIVTEYMPNGSLNELLHRKTEY- ...|..|.|..|||..|...||.|. .|.||...|.||.....||...||.|...|.||.|.|...|. .|||.|||.||||...||.|..| VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ -PDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQS--------RSSKSAPEGGTIIYMPPENYEPGQKS ....||||.|..|||..|..|||.|.||..|.|||..|||.||.||||||||||..|.|.| |.. .|.||....||..|||||......|. HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK R---ASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDI-PHRARMISLIESGWAQNPDERPSFLKCLIEL . .. |.|.||.|...||||..|.|.||......||....||||| ..... .... ||...||.|....|.|.|..||.|. | . PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT |
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| Kinase | RIPK2.AA | TKL | 24-290 | 23 | 6.2e-89 | 301.77 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 24-290
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)
LSRGASGTVSSARHADWR--------VQVAVKHLHIH------------------------TPLLDSERKDVLREAEILHKARFSYILPILGICNEPEF-
. .|..|.| ... |. |||| ...| | . .|. .|. .... | |....|.|..|..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------LGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMT------PPLLHHDLKTQNILLDNEFH-------------
|.||.||.|.||| ..|| |..|.|. ..||.|.||||.|. ||..| |||..|||.|. ..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW
-VKIADFGLSKWRMMSLSQSRSS--------------KSAPEGGTIIYMPPENYEPG-------------QKSRASIKHDIYSYAVITWEVLSRKQPFED
.||.|||||.. .| ...... .. ...||. .|.|| . ... .| |.|.||.... ||.|.|..|..|
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD
VTNPLQI---------MYSVSQGHRPVINEESL-----PYDIPHRARMISLIESGWAQNPDERPSFLKCLIEL
.. .| |. .. |.|| | .. . . . .|..|.. |...|..||||...| .|
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | RIPK2.AA | MLK | 18-290 | 25 | 4.5e-54 | 185.96 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 18-290 Range on HMM: 1-291/291 Sequence Identity: 25% (78 aa) LADLRYLSRGASGTVSSARHADWR---VQVAVKHLHIHT---PLLDSERKDVLREAEIL----HKARFSYILPILGICNEPEF-LGIVTEYMPNGSLNEL . .... |..| | ..| . |||| .. . ..|..|. .|...| |. ...| ...|.|..|. ..||.||...|||... IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LHRKTEYPD-----------VAWPLRFRILHEIALGVNYLHNMTP-PLLHHDLKTQNILLDN------EFHVKIADFGLSKWRMMSLSQS-RSSKSAPEG || .. .. . . ... . .| |..|||.| | |. |.||| .|||.|. . ..||.|||.| |... ... . |. LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS--RDWHQMCTNMMSN----A GTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFE-DVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKC || ..| || . . .. |.| |..|..|. ||.|.|. |.. .. . ... . | || | . ... .|.. | |.| .|||| . GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST-------CPEHWKKLMKQCWNQDPHKRPSFRQI LIEL . .| VQHL |
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| Kinase | RIPK2.AA | TKL-Unique | 20-290 | 25 | 1.6e-42 | 147.6 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 20-290
Range on HMM: 1-290/290
Sequence Identity: 25% (76 aa)
DLRYLSRGASGTVSSARHADW-RVQVAVKHLHIHTPLLDSERKDVLREAEILHKAR-FSYILPILGICN----EPEFLGIVTEYMPNGSLNELLHR----
.. . .|..|.| .. | . .||.| .|. . ..... .| .. | . |. . |.| | . ||.||.| |||...||.
FWNKIGEGGYGQVY---KGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN
----KTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNE-----FHVKIADFGLSKWRMMSLSQSRSSKS----APEGGTIIYMPPE
. ... . .| .. . ||.| .|||. || .| |||..|.|.||. . .||.|||||| . .. . . .. . . |....|.||
NNNNNNNCK-LNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE
NYEPGQKSRASIKHDIYSYAVITWEVLSRKQ------PFEDVTNP--LQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLI
. . |.| |.||.... || ..||. |..... ... .. . || | ...|... . ||. .|...|..|||| .
VLRMNF-CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIP-NHCPKEYRD------LIQQCWHHDPSQRPSFDEIIH
EL
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RL
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| Kinase | RIPK2.AA | Pkinase | 18-287 | 20 | 1.4e-41 | 148.09 | Pfam | 1-288 (293) | Show / Hide |
Range on Protein: 18-287 Range on HMM: 1-288/293 Sequence Identity: 20% (61 aa) LADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVL-REAEILHKARFSYILPILGICNEPEFLGIVTEYMPNG----SLNELLH--RK . .| . .|..|.| ..| . . .|||| . .. . .. ... .|..|... . .|. ..... .. . .|.||...| .| .... |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH TEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHV----KIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRA . . . ... .|. |..|.|.| .| ||| .|||.||. |. ||.||||.| .. ..| ||. ||.|| . GCFY-FSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAK--QFD--Y-NNS-MTTFCGTPWYMAPEVIR--GGQYY SIKHDIYSYAVITWEVLSRKQPFEDV--TNPLQIMYSVSQGHRPVINEESLPYDIPHR-----------------ARMISLIESGWAQNPDERPSFLKCL . | |..|. .| .|.|... || . . . .. . . .. ..... |.... . ....|.. ....| .||.. .| GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL |
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| Kinase | RIPK2.AA | LRRK | 65-292 | 29 | 4.8e-41 | 142.69 | In-house | 106-351 (351) | Show / Hide |
Range on Protein: 65-292
Range on HMM: 106-351/351
Sequence Identity: 29% (74 aa)
REAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYP------DVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILL---D
.|. |... . ..|....|.| .| | .|.||.|.|.|...|| | ... . | |. .| .|| |..|||. .||..| |||. |||| .
HEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSP
---------NEFHVKIADFGLSKWRMMSLSQSR-SSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRK-QPFEDVTNP--LQIMYSV
.. ..||||||.| | . .. ... .|....| || . .. . | |.||...| || |.|. .||.. . . .| |. .
QNHSPNYPNAHVCAKIADFGISR--MFQCFHMGVAKGC---VGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI
SQ----GHRPVINEE-SLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEP
.. |.||.|... .| .| .. .||.. |...|..||.| . . |.
EDKIIEGLRPTIPQHYCPPCQPWH--MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
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| Kinase | RIPK2.AA | TKL-ciliate1 | 93-290 | 29 | 5.6e-39 | 131.04 | In-house | 76-279 (279) | Show / Hide |
Range on Protein: 93-290 Range on HMM: 76-279/279 Sequence Identity: 29% (61 aa) IVTEYMPNGSLNELLHRKTE--YPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSA----PE |..|. . |.. ...||| |. | | |.. .|| |. ||| .|| | ||| ||||.| .. || .|. | . . |. . IIMEHCHKGTMFDICHRKHSQIYM-IKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRIRNCSFQDMQNEMQR GGTIIYMPPENYE----PGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGH-RPVINEESLPYDIPHRARMISLIESGWAQNPDERP .| .| || |.. ..| |||.|... .. .|| ||. . . || .. . || . ...| | . .. |. | ||| || NTTFHWMAPEQMDPHIFPNYP--INEKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHFDCP--QNFHNLMMRCWCQNPNKRP SFLKCLIEL .| . | NFNEIIQIL |
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| Kinase | RIPK2.AA | S_TKc | 18-294 | 21 | 1.1e-37 | 132.47 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 18-294 Range on HMM: 1-231/231 Sequence Identity: 21% (64 aa) LADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPN--GSLNELLHRKTE--- || . .|| |.| .|| . .||.| .. ....|| .||.| . .| ..... . ..| .|.||... |.| ...... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---YPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASI- .| .|. .....|.....|.|.. .| ||| .|||||. |.||.||||.. || ||.|| . RFPFPEHAR----FYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL------GYGKC KHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLI-----ELEPVL | |..| .| .| |... ||. .. ... . ....|. . .|..||. ..| . | . KCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | RIPK2.AA | TK | 18-290 | 13 | 1.3e-35 | 116.29 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 18-290
Range on HMM: 1-486/486
Sequence Identity: 13% (68 aa)
LADLRYLSRGASG---TVSSA---RHADWR----------------------VQVAVKHLHIHTPLLDSERKD--------------VLREAEILH--KA
. .. | .|. | .| . .. .|. ..|||| |. ... . |..| ..|..... .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
RFSYILPILGICNEP------------EFLGIVTEYMPNGS----LNELLHRKTEYPD------------------------------------------
. |. ..|.| .. | . ||.||||.|. | . |... ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------VAWPLRFRILHEIALGVNYLHNMTP----PLLHHDLKTQNILLDNEFH-----------VKIADFGLSK
. . . . . || | ||| . . | || . |.|.... . .||||||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
W----RMMSLSQSRSSKSAPEGGTII-------------------------YMPPENYEPGQ------KSRASIKHDIYSYAVITWEVLS--RKQPFEDV
. . .. .. ..|| .|.|| . .. . . ..| |..|. | ||... .... ...
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
TN--------PLQIMYSVSQG--------------HRPVINEESLP---YDIPHRA-----RMISL-IESGWAQNPDERPSFLKCLIEL
.| . ..| . .| .|. . . | . | .. . . . |. .|..||.| .. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | RIPK2.AA | HH498 | 44-290 | 27 | 5.9e-34 | 104.74 | In-house | 25-284 (284) | Show / Hide |
Range on Protein: 44-290 Range on HMM: 25-284/284 Sequence Identity: 27% (75 aa) VAVKHLHIHTPLLDSE-----RKDVLREAEILHK-ARFSYILPILGICNEPEFLGIVTEYMPNGSLNELL--------------HRKT-EYPDVAWPLRF |||| . . . |. . ||. |. . . .. . . |..| . |||.| |||| .| | | . . VAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIGGAGANNNNHNQKNNYRIMDLQSKM RILHEIALGVNYLHN-MTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPE-GGTIIYMPPENYEPGQKSRASIKHDIYSYAVITW .| ..| | ||||| ...| | || .|||.. . | ..|||| | ... . | .| || . | . ||| |..||| . | TISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFV-----CDMHDDNMTKQPGNLRWMAPEVFS--QCQKYSIKVDVFSYAMCIW EVLSRKQPFEDVTNPLQIMYSVSQGH-RPVINEESLPYD----IPHRARMISLIESGWAQNPDERPSFLKCLIEL | ..|. || . | . | || .|. ||| . ..|| .| ..|..||.| . | EMHTREVPFHHY-KPAAAAAEMAYHHIRP-----PIPQTPTAQIPH--HWSNLIQMCWHPCPENRPDFDQIVTIL |
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| Kinase | RIPK2.AA | DRK | 61-168 | 39 | 1.2e-29 | 97.59 | In-house | 42-147 (258) | Show / Hide |
Range on Protein: 61-168 Range on HMM: 42-147/258 Sequence Identity: 39% (43 aa) KDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHV .. ||.... . | | .| ||.| |..|||| ||| || | |||. .. .| |..|||. .| .| |||. | | | . | NEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH--DESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQV KIADFGLS |.|||||| KVADFGLS |
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| Kinase | RIPK2.AA | Dicty4 | 82-169 | 38 | 3.4e-29 | 94.67 | In-house | 64-162 (277) | Show / Hide |
Range on Protein: 82-169 Range on HMM: 64-162/277 Sequence Identity: 38% (39 aa) LGICN----EPEFLGIVTEYMPNGSLNELLHR-------KTEYPDVAWPLRFR---ILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGL .| |. .|. . ||||||| |.| .||| ... . |||. | . .|.|.|.||. .| .| |||. |.| | . ||..|||| MGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLD---WPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGL SK |. SQ |
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| Kinase | RIPK2.AA | TyrKc | 18-290 | 24 | 1.2e-28 | 102.41 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 18-290 Range on HMM: 1-280/280 Sequence Identity: 24% (74 aa) LADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKA--RFSYILPILGICNEP-------EFLGIVTEYMPNGSLNELLH . .. | .|| |.| .. .||||| |. .. |.| .|||.|..| . |. ..|.| .. | | ||.||||.|.|.. |. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR RKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMS-------LSQSRSSKSAPEG-GTIIYMPPENYEP .. . . .. . . || | .||| . .. | || . |.|......|||.|||||. . .... . | |.|| KHRPK--LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- GQKSRASIKHDIYSYAVITWEVLSR-KQPFEDV----TNPLQIMYSVSQGHRPVINEESLPYDIP-----HRARMISLIESGWAQNPDERPSFLKCLIEL .... ..| |..|. | ||.... .|| ... .. ... | ||.|. . .. . | . | ..... |. .|..||.| . .. -NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | RIPK2.AA | Pkinase_Tyr | 26-169 | 29 | 2.6e-23 | 79.56 | Pfam | 9-159 (270) | Show / Hide |
Range on Protein: 26-169 Range on HMM: 9-159/270 Sequence Identity: 29% (46 aa) RGASGTVSSARHA----DWRVQVAVKHLHIHTPLLDSE---RKDVLREAEILHKA-RFSYILPILGICN-EPEF--LGIVTEYMPNGSLNELLHRK-TEY .|| |.| .. . ...|||| | . ..| |.| .|||.|... . |. .|.| . | . ||.||||.|.| . |... .. EGAFGEVYKGTWKGDPDNTKIPVAVKML---KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK PDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSK . . . . ..|| | .||... . | || . |.|......|||.||||.. QPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLAR |
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| Kinase | RIPK2.AA | DRK | 209-292 | 32 | 7.3e-14 | 43.37 | In-house | 182-258 (258) | Show / Hide |
Range on Protein: 209-292 Range on HMM: 182-258/258 Sequence Identity: 32% (28 aa) KHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQ-GHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEP | |.||.|.. ||.. |. |. . ...|. || . | || . | | . | |. | .| |||. || || KADVYSFAIVLWECVTRQDPYFGM-PTFQVVFSVGRHGMRPPM-----PQWCP--PKYIQLMNDCWNEDPQHRPSMQECLERLEA |
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| Kinase | RIPK2.AA | Dicty4 | 211-292 | 29 | 9.6e-08 | 22.09 | In-house | 199-277 (277) | Show / Hide |
Range on Protein: 211-292 Range on HMM: 199-277/277 Sequence Identity: 29% (25 aa) DIYSYAVITWEVLSRKQPFE-DVTNPLQIMYSVSQ-GHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIE--LEP | ||.. . || | |. |. .. |. .| . . || | | . | .. ..||. | .| |||| .. . || DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPI-----PDWCP--PSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | RIPK2.AA | Pkinase_Tyr | 273-290 | 33 | 0.003121 | 11.57 | Pfam | 253-270 (270) | Show / Hide |
Range on Protein: 273-290 Range on HMM: 253-270/270 Sequence Identity: 33% (6 aa) WAQNPDERPSFLKCLIEL |...|..||.| .. .| WHYDPEDRPTFSEIHEQL |
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| Kinase | RIPK2.AA | Pkinase_Tyr | 211-247 | 22 | 7.653163 | 0.09 | Pfam | 196-234 (270) | Show / Hide |
Range on Protein: 211-247 Range on HMM: 196-234/270 Sequence Identity: 22% (9 aa) DIYSYAVITWEVLS-RKQP-FEDVTNPLQIMYSV-SQGHR |..|. | ||... .|| .... . ... . .|.| DVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDGYR |
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| CARD | RIPK2.AA | CARD | 437-524 | 25 | 6.1e-24 | 88.73 | Pfam | 1-90 (90) | Show / Hide |
Range on Protein: 437-524 Range on HMM: 1-90/90 Sequence Identity: 25% (23 aa) QQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVST--KPTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEIL .......|. .|...|..|... ||.|....... |.||... ..|| .|.|.|||. .|.. ... .| |....|. |... | . WHFLRKHRMALVQRLTMECVDGLLDHLREKNVLTWEEYEEIKCAYCTTRMDKARELLDMVQKKGPWACQIFLQCLCETGQPHLADDLEHQ |
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