Gene SGK1 (Human)

SGK1

Species: Human
Alias: SGK, SGK1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 6q23.2,

Classification

Group: AGC
Family: SGK

Sequence

Name Sequence Type Origin Length Description Download
SGK1.NA RNA Sugen Kinome 3208 None Fasta, JSON
SGK1.AA Protein Sugen Kinome 526 None Fasta, JSON
SGK1.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of SGK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SGK1.AA SGK 193-450 66 7.2e-229 714.66 In-house 1-283 (283) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-283/283
Sequence Identity: 66% (189 aa)

FHFLKVIGKGSFGKVLLARHKAE------------------EVFYAVKVLQKKAIL-------KKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKL
|.|||||||||||||....||..                  . |||.|||||..|.       ||||.||||.||||.|||.||||.|.||..|||..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ
|||.||.||||.|||||||..|.|.|||||||||..||.||||..|.||||||||||||.|||..|||||||||.|..| ||.||||||||||||||.||
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF
|.||||||||||.|||||.||||||||||...|||||.|.|||..|...|.|..|..||||||..||||.|.||||||.|.||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase SGK1.AA AGC 193-450 36 2.3e-195 510.91 In-house 1-395 (395) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-395/395
Sequence Identity: 36% (147 aa)

FHFLKVIGKGSFGKVLLARHK------AEEVFYAVKVLQKKA-ILKKK--EEKHIMSE------------RNVLLKNVK---------HPFLVG-LHFSF
|.||||||||||||| |.|.|      . . .||.|||.||  |..||  ...|.|.|            ||.| |  .         |||.|  ||.||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTADK--LYFVLDYIN---------GG-ELFYHLQ---RERCFLEPRARFYAAE-------IASALGYLHS-LNIVYRD-LKPENILLDSQGHIVLTDFG
|. |.  ||||..|..         || |||.|||   .|..| |.||||||||       |..|| |||| ..|..|| |||||||||..||| |||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKENI--------------------------------------------------EHNSTTSTFCG--TPEYLAPEVLHKQPYDRTVDWWC--LGAVLY
||||..                                                  . . .|.||||  ||||.|||.|    |....|||.  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLYGLPPFYSRN----------TAEMYDNIL------NKPLQLK----------PNITNSARHLLEGLLQKDRTKRLGAKDD------FMEIKSHVFF
|||.|.||||. |           .||...|.      |.....           ..... |..|...||.||..||||....      . |||.| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase SGK1.AA Akt 193-450 56 3.3e-172 554.86 In-house 1-264 (264) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-264/264
Sequence Identity: 56% (149 aa)

FHFLKVIGKGSFGKVLLARHKA-EEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLE
| ||||.||||||||.|.. |. ....|| |||.|. |..|.. .|.. |||. |....|||.|.||.||||.||||||.||.|||||||||||.| | |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNI-LQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

PRARFYAAEIASALGYLHSLNIVYRD-LKPENILLDSQGHIVLTDFGLCKEN-IEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWC-LGAVLYEMLYG
.|||||.||| .|...||| ||.||| |||||||.|..||| |||||||||| | .. .| ||||||||||||.| .. ....||||  ||.|.|||..|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

LPPFYSRNTAEMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKRLG-AKDDFMEIKSHVFF
.||||...  .|...|.|.|.. .  ..| . .. |..|||.||..|||| ...|  |||.| .|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase SGK1.AA AktR 193-450 44 1.4e-129 436.76 In-house 1-268 (268) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-268/268
Sequence Identity: 44% (119 aa)

FHFLKVIGKGSFGKVLLARHK-AEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLE
||..|..||| |||| |...|  .  .|| |.. || | ... ..|.  |||.. . ..|||.| ||..||| .||.|...|. |||||.||.... | |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PRARFYAAEIASALGYLHSL-NIVYRDLKPENILLDSQGHIVLTDFGLCK-ENIE-HNSTTSTFCGTPEYLAPEVLHK-QPYDRTVDWWCLGAVLYEMLY
 .||||.|.|  || |||.  ||.||||||||||||. ||. .||||| | ....  . .. .|||||||.|||.. | ......||||..|...|||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYSRNTAEMYDNILNKP-LQLKPN--ITNSARHLLE-GLLQKDRTKRLG-AKDDFMEIKSHVFF
|.||||. |. .|...|..|. .. ...  ... .. |.. .||.|. .|||| .. .. ||||| .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase SGK1.AA PKC 193-450 46 1.2e-128 419.2 In-house 1-262 (262) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-262/262
Sequence Identity: 46% (123 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP
|.||||.||||||||.||..|  . .||.||| | .|..       | |. ||    |||||..|| .||| |.|.||. |.||| | .| |. | | |.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF
.||||||||..|| .||. .|.||||| .|.|||. ||| ..|||.||||.   .|||||||||.|.|||.|  |.|   |||| .|  .|||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDD----FMEIKSHVFF
   .  |. ..|...       ..  | ....|...|. .||||.. .    ...|..| ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase SGK1.AA PKA 193-450 44 2.6e-126 425.95 In-house 1-263 (263) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-263/263
Sequence Identity: 44% (118 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG-LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLE
| .....|.||||.| |.|||  . .|| |.| |  | . | . |...|.|. |.|.||||.|  . ..||....||.|..|..|||.|..|.....| .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNI-LQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

PRARFYAA-EIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ-PYDRTVDWWCLGAVLYEMLYGL
| |.|||| .| .|| ||||.||.||||||||||.|..||| .||||  |. ..    |.| ||||||||||..    .. . ||||.|| . |||| | 
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGY

PPFYSR--NTAEMYDNILNKPLQLKPNITNSA---RHLLEGLLQKDRTKRLGAKD-DFMEIKSHVFF
||||    .....|. |.|  ..  ..... |   ..|.. |||.|.|||.| .. .   || | .|
PPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase SGK1.AA RSK 196-450 44 2.4e-125 422.72 In-house 1-278 (278) Show / Hide 
Range on Protein: 196-450
Range on HMM: 1-278/278
Sequence Identity: 44% (124 aa)

LKVIGKGSFGKVLLARHK---AEEVFYAVKVLQKKAILKK-KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERC---
||| |.|..||| | | .   . .  ||.|||.|. | .. |  .| | |||.|.   .|||.| || .||| .||| ...|..|||||.|||.|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDS---QGHIVLTDFGLCKE-NIEHNSTTSTFCGTPEYLAPEVLH---KQP-YDRTVDWWCLGA
| | .|.||.|||..|. .||.. |..|||||||||.|.   .|||.|||||.||. ...||. | |||.| ||.|||.|    .|  .|. .||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VLYEMLYGLPPFYS---RNTAEMYDNILNKP--LQLK--PNITNSARHLLEGLLQKDRTKRLGA-KDDFMEIKSHVFF
..|||| | |||..    | .|  ..|...   | ..  ..... |..|. ..|..|  ||||. ..|  |||.| .|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase SGK1.AA RSK-Unclassified 193-450 41 4.2e-113 356.71 In-house 1-283 (283) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-283/283
Sequence Identity: 41% (118 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQ--RERCFL
|   . ||.|.|||| | | |  .  || |||.|. .....  | .| |.|..    .||| | | .|||| |.|| ...|  ||..| |||  .|.|| 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMAT-TNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFC

EPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKEN---------------------IEHNSTTSTFCGTPEYLAPEVLHKQPY
| ..||||.|.  || ||| . ..||||||.||.|.  ||. ||||.| ..                      ..| . |  |||| ||||||..     
EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGH

DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKRLGAKDD-FMEIKSHVFF
 . |||| || |.|||| |.||.|  |. |.. ||. .....     | | .| |.  |||.   ||||.|     .|| | ||
TKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase SGK1.AA p70 193-450 42 4.6e-112 378.61 In-house 1-299 (299) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-299/299
Sequence Identity: 42% (126 aa)

FHFLKVIGKGSFGKVLLARHKA---EEVFYAVKVLQKKAILK-KKEEKHIM-------------------------SERNVLLKNVKHPFLVGLHFSFQT
|  |||.||| .|||.. |  .   .   || |||.|  |.   |   |                            |||. |  |||||.. ||..|||
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNI-LEEVKHPFICDLHYAFQT

ADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNST----------TSTFC
  ||| .|.|. |||||.|| |.  ..|  |.||..||  ||..||.. |.||||||||..|..|||.|||||||||| |.  .           | |||
NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC

GTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKP--LQLKPNITNSARHLLEGLLQKDRTKRLG-AKDDFMEIKSHVFF
||.|| |||.| .  ... |||| ||. .| || | |||   | ..  | ||     |.| |  |...| |.  || .. |.|.|   .|  .|..| ||
GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase SGK1.AA S_TKc 193-450 38 1.8e-108 367.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-231/231
Sequence Identity: 38% (104 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYING--GELFYHLQRERC--
...|..||||.|||| ..|||     .|.|..           .||..|...| |  .||..| |. .||. |.||.|..|..|  |.|| .... ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR-TVDWWCLGAVLY
    | | .||||...|..|| |.||..|..|||||||||||.  || ..||||...        .||||||.|.|||||   .|..  .||| .| .||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFM---EIKSHVFF
|||.| |||.  . ..|...|.          . .|.......|||| .||..| . .    .||.| .|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SGK1.AA Eta 193-450 46 1.2e-106 360.57 In-house 1-261 (261) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-261/261
Sequence Identity: 46% (122 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP
|.|.||.||||||||.||..|  .  ||.|||.| .|..  .    | |. .|    |||||  || .||| |.|.||..|.|||.| ...|| | | ||
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF
||||||||. .|| .||  ...||||| .||||| .||  | |||.||| | .. ||.||||||.|.|||.|. . |  .|||| .| ..|||. | |||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

YSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAK---DDFMEIKSHVFF
   |  .... ||.        . . |  .| . . |  .||||.    ..  .|..| ||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase SGK1.AA Pkinase 193-450 33 1.2e-91 315.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 193-450
Range on HMM: 1-293/293
Sequence Identity: 33% (101 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIM-SERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGG----ELFYHLQ--R
.|....||.||||.| ...|| ..  .|||.. |. . ..|.. |.  ||  ....  .||. | |. .|.. |..|.|..| .||    .|| ...  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ERCF--LEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI----VLTDFGLCKEN-IEHNSTTSTFCGTPEYLAPEVLH-KQPYDRTVDWWC
..||   |  ..||. .|...| |.|| .|..|||||||||.|..|||     ..||||.|   . .|| ..||||||.|.||||.   |.|.. ||.| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGAVLYEMLYGLPPFYSR------NTAEMYDNILNKPLQLKPNIT---------------------NSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFF
.| .||||| | |||...      .  .|...|. .||      .                      .........|.|| .||..    ...|. | .|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQILQHPWF
Kinase SGK1.AA S_TK_X 451-520 33 7.1e-20 73.28 SMART 1-79 (79) Show / Hide 
Range on Protein: 451-520
Range on HMM: 1-79/79
Sequence Identity: 33% (28 aa)

SLINWDDLIN--KKITPPFNPNVS----GPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAA-------EAFLGFSYAP
. |.||.| |  |.|.||| |...    .| |.. ||||||||..      .||.  ...|. . .       . |.||.|  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase SGK1.AA TyrKc 193-448 20 7.6e-14 1.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 193-448
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN-VKHPFLVGLH-FSFQTA------DKLYFVLDYINGGELFYHLQ
 ...|..| | ||.| ... |   .  |||.|.. |      .. .|.| ... |   .|| .| |.    |        . |. |. |  .| |  .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RERC-FLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEH-------NSTTSTF--CGTP----EYLAPEVLHKQPYD
. |  .  .    ..  ||.   |||| |.. |||   |.|.......  .||||...  ..          ...   .|        .|||.. .  . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

RTVDWWCLGAVLYEML-YGLPPFYS-----RNTAEMYDNILNKPLQLKPNI---------TNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHV
   | |  | ...|.. || .| .       . .|.. .. .     .|           .     . .   . |  .|      | ||..  
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP----TFSEIHECF
Kinase SGK1.AA Pkinase_C 470-522 32 3.2e-12 46.26 Pfam 1-46 (46) Show / Hide 
Range on Protein: 470-522
Range on HMM: 1-46/46
Sequence Identity: 32% (17 aa)

NVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT
.|..| | ..||||||.||.. .       .  . . ... |.| ||.| .| 
QVKSPTDTSNFDPEFTDEPPMDTP------PDWR-MSSGDQEPFRGFTYVNPD
Kinase SGK1.AA Pkinase_Tyr 193-340 25 3.1e-08 28.5 Pfam 1-159 (270) Show / Hide 
Range on Protein: 193-340
Range on HMM: 1-159/270
Sequence Identity: 25% (42 aa)

FHFLKVIGKGSFGKVLLARHK------AEEVFYAVKVLQKKAILKKKE--EKHIMSERNVLLKNV-KHPFLVGLHFSFQ-TADK--LYFVLDYINGGELF
 .|.|..|.|.||.| ... |        .|  |||.|  |    ...   .  |.| .. .|.  .|| .| |.       .   .| |. |  .| | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV--AVKML--KEGAMHEQNCREDFMREAKI-MKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

YHLQR----ERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK
 .|..    .. .  ..   ....||... ||.| |.. |||   |.|.......  .||||..
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase SGK1.AA Pkinase_Tyr 359-404 25 6.457225 0.34 Pfam 181-228 (270) Show / Hide 
Range on Protein: 359-404
Range on HMM: 181-228/270
Sequence Identity: 25% (12 aa)

LAPEVLHKQPYDRTVDWWCLGAVLYEMLY-GLPP-FYSRNTAEMYDNI
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MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI