Gene STLK3 (Human)

STLK3

Species: Human
Alias: SPAK, STLK3, PASK, DKFZp686K05124, STK39, DCHT
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: 2qq31.1,

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
STLK3.NA RNA Sugen Kinome 3288 None Fasta, JSON
STLK3.AA Protein Sugen Kinome 545 None Fasta, JSON
STLK3.kin_dom Protein Kinase Domain Sugen Kinome 275 None Fasta, JSON

Protein domain

Protein domains of STLK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase STLK3.AA FRAY 63-337 77 5.2e-251 788.54 In-house 1-277 (277) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-277/277
Sequence Identity: 77% (214 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQ-TSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGE-HK
||||||||.||||||..|.|.||||..||||||||||| ||||||.||||||.||.|||||.|.|||||..||||||..|..||.|||.|.....|| ||
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
.||..|..|||||||||.||.|.|.|||||||.||||||.||||..|||||||||.||||||..|..||.|||||||||||||||||.|||||||.||||
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
|||||||||.|||||||||||||||||||||.|||...||.|.||||.||.|... ||||||||||||.||||.|||
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase STLK3.AA STE20 63-337 47 1.7e-151 509.61 In-house 1-288 (288) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-288/288
Sequence Identity: 47% (142 aa)

YELQEVIGSGATAVVQAALCKPRQER----VAIKRINLEKCQ---TSMDELLKEIQAMSQCSHPNVVTYYTSFVVK----DELWLVMKLLSGGSMLDIIK
|||.|.||.|.. .|  | .|| .|     ||||..|||||.    ......|||. |.|| |||.|.||.|....    ||||.|| ...||| .||.|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

YIVNRGE-HKNG-VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLAT--GGDVTRNKVRKTFVGTPCWMAPEVMEQV
  ...|  || | ...|. ||.|..|||.||||||.|..||||.||.||||.|||.|..|||||.| | .  . | |... |.||||||.||||||....
HCMKCGKNHK-GHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCM

----RGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--QNDPPTLE-TGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
     |||.|.| ||.||||||.|.|  ||....||.......  ||.||||. .        .|. ..|. ....||||||.||||| .||| .|.
EGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDD-K-----PHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase STLK3.AA STE 63-337 33 8.70000000001e-125 420.86 In-house 1-359 (359) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-359/359
Sequence Identity: 33% (124 aa)

YELQEVIGSGATAVVQAALCK------PRQER---------VAIKRINLEKCQ----------------TSMDELLKEIQAMSQCS--HPNVVTYYTSFV
.|..|.||.||. .|  |...      . .|          .|||..|||.|.                . |...||||. |..|.  |||.|.|| ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VK-------DELWLVMKLLSGGSMLDIIKYIVNRGEHKN------GVLEEAIIATILKEVLEG-LDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSA
..       ||||..| ...|||  ||||    .|.  |      ....| .||.|....|.| |.|||... ||||.|..||||     | ..||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FLATGGD-----------VTRNKVRKTFVGTPCWMAPEVMEQ-----VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQN-----------
 |.  ..            |. . |.|||||| ||||||..|     . |||.|.|.||.|.|.||.|||  |.|...||........|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DPPTLETGVEDKEM----------MKKYGKSFRKLLSLCLQKDPSKRPTAAELLK--CKFF
    .||.|.. ....||           .|. ..|.  ...||||||.||||| .|||   .|.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase STLK3.AA YSK 63-337 44 2.1e-105 318.36 In-house 1-257 (257) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-257/257
Sequence Identity: 44% (125 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKY-IVNRGEHKN
.  ||.|| |   .|  .  .  |. |||| |.||.     . . .|||  |||  |..  || |.     || .|  . |||.|| .|   |       
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYV-------

GVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVT-RNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADMWSF
| ..|  ||.||.|.| |||||| .  |||| || |.|| |.| | ..||||.      | .|   . | |||||| ||||||  | | .||||||.|| 
GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVA------GQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSL

GITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
||||.|.|.|  || .| ||.|. |   | ||.||         ..| |.|     .|| |||..||.| |||| || 
GITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG--------RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase STLK3.AA PAKA 63-337 37 2.6e-82 279.78 In-house 1-260 (260) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-260/260
Sequence Identity: 37% (107 aa)

YELQEVIGSGATAVVQAALCKPRQER--VAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIV----NR
|.  | || ||.  |  |  .  ...  ||||..|... | ... .. ||  | .| |.|.| |. |..|.||||.||  ..||.  |.|.       | 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN-

GEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTR-NKVRKTFVGTPCWMAPEVMEQVRGYDFKAD
      ...|..|| ...|.| ||...|....||||.|  ||||| |||| |.|||  | |      |. .  |.| |||| ||||||  . . || | |
------YMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQL------TQEQQKRNTMVGTPYWMAPEVIRR-KQYDEKVD

MWSFGITAIELATGAAPYHKYPPMKVLMLTLQN-DPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
 || || |||.. |  || ..|| . . |  .|  |. ...         |  ..|.. |..||..|. .|..| |||.  |.
IWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDP--------DKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase STLK3.AA S_TKc 63-337 30 2.7e-82 280.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-231/231
Sequence Identity: 30% (87 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSG--GSMLDIIKYIVNRGEHK
||. ..||.|| ..|  .  |  ...||||.|.        . ...||| ...  |||.|..| .|.  |.|..|| ...|  |...|.||    .|  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG--L

NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDF-KADMWSF
. .. |  .. ........|.|.|..| ||||||  |||| |   . |.|||....|            .||.||| .|||||.    ||.. |.|.||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK-------CKFF
|.. .|...|  |..   ..... . .                     .... ... ||||||.||||| |.|.         .|
GCILYEMLCGYPPFP--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase STLK3.AA MST 63-293 41 3e-73 232.18 In-house 1-217 (254) Show / Hide 
Range on Protein: 63-293
Range on HMM: 1-217/254
Sequence Identity: 41% (97 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFV--VKDELWLVMKLLSGGSMLDIIKYIVNRGEHK
... | .| |.  .|  |..|   . |||| .. .   . ..|..|||  |.||  ...|.|| |.      ..|.||    .|| .||.| | .|    
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVN---EDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMK-ITQR----

NGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
  .| |. ||.||. .| ||.|||.|  ||||.||||||| ..|    ||||||. |       ..  | |..|||.|||||| ... .|| ||| || |
--TLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQL-----TDTMAKRNTVIGTPYWMAPEVIQEI-KYDCKADIWSLG

ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTL
|||||.| |  ||.   || .. .  |. |||.
ITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTF
Kinase STLK3.AA Pkinase 63-337 28 4e-69 240.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLK---EIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGG----SMLDIIKYIVN
|.. ..||||. ..|  .  |  ...||.|.|....   ..|. .    ||| |  ..|||.|..| .|  ||....|| .. ||    .  |.|.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

RGEHKNGVL--EEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSV----QIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRG
   ...|..  .|  .  .....|.||.|.|..| ||||||  |||. ..| .     |.|||.....       .|   .||.||| .|||||    ..
---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQY

YDFKADMWSFGITAIELATGAAPYHKY------PPMKVLMLTLQNDPPTLETGVED------------KEMMKKYGKSFRKLLSLCLQKDPSKRPTAAEL
|. |.||||.|.. .|...|  |.          .|... .... ...  .    .            ..  ..  ........ ||.|||.|||||...
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI

LKCKFF
|. ..|
LQHPWF
Kinase STLK3.AA KHS 63-337 40 6.4e-68 227.5 In-house 1-258 (258) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-258/258
Sequence Identity: 40% (113 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNG
|||   .|||    |  |  .  .| .|.| | .|  .  .  . .||  | .|.|||.| |. |.. .| ||..|    |||. ||         |  |
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME-PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIY--------HVTG

VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEV--MEQVRGYDFKADMWSFG
 |.|  || . .|.|.||.||| .|..|||.|  |||| ..| |..||||||| ..     | .| || |.||| ||||||  .|.  ||.   |.|. |
PLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITA----TIAK-RKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVG

ITAIELATGAAPYHKYPPMKVLMLTLQND--PPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
|||||||    |     ||..|.|  . .  ||.|    .||.   |. ..| . . ..| |.| |||||  ||. .|.
ITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL----KDKH---KWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase STLK3.AA SLK 63-337 37 2.8e-66 222.57 In-house 1-259 (259) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-259/259
Sequence Identity: 37% (105 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNG
.|.   .| ||   |. |  | ..   | | |.... .  ... . ||. .|.| |||.|  | .. . ..||...    || .  |.  .       . 
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKD-EEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVEL-------EH

VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM--EQVRG--YDFKADMWS
.|.|  |. . |...|.|..||.|  |||||||||||.  || |..||||||| .      |..| | ||.||| ||||||.  | ..   ||.|||.||
PLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKH----TMQK-RDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWS

FGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
.||| ||.| .  |.|   ||.||.   . .|||||.         .. |.|. .|  ||.||| .|.|.|.|.. ...
LGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQ-------PSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase STLK3.AA TKL 69-333 22 1.4e-57 197.63 In-house 1-362 (364) Show / Hide 
Range on Protein: 69-333
Range on HMM: 1-362/364
Sequence Identity: 22% (84 aa)

IGSGATAVVQAALCKP--------RQERVAIKRINLEKCQTSM--------------------------DELLKEIQAMSQCSHPNVVTYYT------S-
||||. ..|  . ..         . . ||.|... . .. ..                          ... .||  ||...|||.| ..       . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-FVVKD-----ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNG--------QIHRDLKAGNILLGEDGS--------
 ....      .|..|| . .||| |...                  .  . ...  |..||| ..         ||||||  |||. |..         
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYN

------VQIADFGVSAFLATGGDVTRNK--------------VRKTFVGTPCWMAPEVMEQV---------------RGYDFKADMWSFGITAIELATGA
      . |.||| | |. . |. ....               . | .|||.||||||...                . |. |.|..||||   |..|. 
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

APYHKYPPMKVL---------MLTLQND-PPTLETGVED--KEM--MKKYGKSFRKLLSLCLQKDPSKRPTAAELLK
 ||..||.| ..         |.  ..  .|.. .  ..  | |   .   .|..||.  | . ||.|||.. |.||
RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHK-MCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILK
Kinase STLK3.AA PAKB 64-337 37 2.1e-57 197.04 In-house 2-252 (252) Show / Hide 
Range on Protein: 64-337
Range on HMM: 2-252/252
Sequence Identity: 37% (104 aa)

ELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELL-KEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNG
.    || | | .| .|  |     ||.|. .| | |    |||  |.  | .  |||.|  | |. | |||| ||  . ||.. ||.     |      
DNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQ--RRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTHT--R------

VLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGIT
 ..|  |||. . ||. |.|||  | |||| |   ||| .|| |   |||  | .    .| .   ||  |||| ||||||      |. ..| ||.|| 
-MNEEQIATVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSK--EVPK---RKSLVGTPYWMAPEVISRLP-YGTEVDIWSLGIM

AIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF
 ||.  |  ||   ||.. .     . || |           |   . | .|. .| .||..| ||.|||.  |.
VIEMVDGEPPYFNEPPLQAMKRIRDMHPPRL-------KNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase STLK3.AA TyrKc 63-337 22 4.4e-28 100.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 63-337
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQC--SHPNVVTYYTSFVVK-------DELWLVMKLLSGGSMLDIIKYI
 .| ...|.||  .|  .  |   . ||.| .. ..    . ....|.. |..   .|||.|  |   . .       . |..|| . ..|. .| ... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

VNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATG------GDVTRNKV--RKTFVGTPCWMAPEVME
 ..       |  .    .   . .| .|||... ||||| | |.|.||.. | |.||| | ..  .      .|. | |    . ..    |||||.. 
RPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

QVRG-YDFKADMWSFGITAIELATGAAPYHKY-----PPMKVLMLTLQND--PPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLKC
   | . .| | ||||..  |. |  .. .        . . ..  ...   .|  . .    . |       . .. . . | . ||..||| .|.  .
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--H

KFF
..|
ECF
Kinase STLK3.AA Pkinase_Tyr 63-282 25 1.1e-27 94.44 Pfam 1-225 (270) Show / Hide 
Range on Protein: 63-282
Range on HMM: 1-225/270
Sequence Identity: 25% (60 aa)

YELQEVIGSGATAVVQAALCK----PRQERVAIKRINLEKCQTS---MDELLKEIQAMSQC-SHPNVVTYYTSFV-VKDE--LWLVMKLLSGGSMLDIIK
 .. ...|.||  .|  . .|      .  ||.| .  |..  .   ......|.. |.|  .|||.| .|   .  ..   ...|| .  .|..||  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

YIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYD
   .|  . .. |    .  .  .. .|..||.... ||||| | |.|..|.. | |.||| .  . .  |    ..|.       |||||..   . . 
--KHR--EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGK-FT

FKADMWSFGITAIELAT-GAAP-YHKYPPMKVL
 | | ||||..  |. | |. | |   ..  |.
TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVY
Kinase STLK3.AA MST 314-337 45 2e-09 26.04 In-house 231-254 (254) Show / Hide 
Range on Protein: 314-337
Range on HMM: 231-254/254
Sequence Identity: 45% (11 aa)

LSLCLQKDPSKRPTAAELLKCKFF
.. ||||.|..|.|| .||.  |.
VCKCLQKNPEQRWTAEQLLQHPFI
Kinase STLK3.AA Pkinase_Tyr 312-337 30 0.211332 5.37 Pfam 247-270 (270) Show / Hide 
Range on Protein: 312-337
Range on HMM: 247-270/270
Sequence Identity: 30% (8 aa)

KLLSLCLQKDPSKRPTAAELLKCKFF
.|. .| ..||..||| .|.    ..
DLMKQCWHYDPEDRPTFSEI--HEQL
FRWNK_Fray STLK3.AA FRWNK_Fray 449-545 65 4.8e-68 232.38 In-house 1-97 (97) Show / Hide 
Range on Protein: 449-545
Range on HMM: 1-97/97
Sequence Identity: 65% (64 aa)

SCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
....|||||.||..|||||||||||||.|||.|..|||.|||||||.|.|||||||||..|.|. .|..||.|.|||...|.|||..||||||.|..
QPPINLVLRMRNQKKELNDIRFEFTPGKDTAEGIAQELVSAGLVDGRDLVIVAANLQKLIDNPQTMKSVTFQLNSGCQPNEVPDEKALIGFAQISIH
OSR1_C STLK3.AA OSR1_C 452-483 36 1.6e-12 49.16 Pfam 1-38 (38) Show / Hide 
Range on Protein: 452-483
Range on HMM: 1-38/38
Sequence Identity: 36% (14 aa)

VNLVLRLRNSRK------ELNDIRFEFTPGRDTADGVS
.||.||.|...|      |...|.|||....||...|.
INLWLRMRDPKKRKGKHKENEAIQFEFDIEKDTPEEVA