Gene Wee1 (Human)

Wee1

Species: Human
Alias: FLJ16446, Wee1, WEE1, DKFZp686I18166, WEE1hu
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards ,
Annotation: Consensus chromosomal location: 11p15 ,

Classification

Group: Other
Family: WEE
Subfamily: WEE1

Sequence

Name Sequence Type Origin Length Description Download
Wee1.NA RNA Sugen Kinome 3374 None Fasta, JSON
Wee1.AA Protein Sugen Kinome 646 None Fasta, JSON
Wee1.kin_dom Protein Kinase Domain Sugen Kinome 271 None Fasta, JSON

Protein domain

Protein domains of Wee1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Wee1.AA WEE 299-569 47 5.70000000001e-169 567.64 In-house 1-297 (297) Show / Hide 
Range on Protein: 299-569
Range on HMM: 1-297/297
Sequence Identity: 47% (143 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLG------QHSHVVRYFSAWAEDDHMLIQNEYCNGGS--LADAISE
|.|..|||.|.||.|.||..|.||||||||.||.|..|. ....||||||||.|||      .| |.|||.|||.|||||.||.|||||||  |...|..
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQ

NYRIMSYFKEAELKDLLLQVGRGLRYIHSM-SLVHMDIKPSNIFISRTSIPNAA---SEEGDEDDWASNKVMFKIGDLGHVTRIS----SPQVE-EGDSR
... . .. |......|... .||..|||. ..|||||||.|||||. ...|..   ......|.| .| .|.||||.||||...    .|..| |||||
CHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWW-FN-MMCKIGDFGHVTDMNSNNNNPHQEQEGDSR

FLANEVLQE--NYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQG-------RLP--RIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVL
..|.|.||.  .||||.|||||.|..|....|....||.|||.||.||||       ..|  .... .|||...|.|.|.|||||.||....|..|.||
YMAPEILQGYYHYTHLYKADIFSLGITIYELACNMDLPKNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase Wee1.AA Pkinase 299-569 25 1.3e-76 265.64 Pfam 1-293 (293) Show / Hide 
Range on Protein: 299-569
Range on HMM: 1-293/293
Sequence Identity: 25% (80 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALR--EVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGG----SLADAIS-EN
.| ..||||| ||.|.||... .|.|.|.|. ||. . |  .|...|  |.. .. | .| ..||.. .. ..||. .  |||.||    .|.| || ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGH-----VTRISSPQVEEGDSRFLANE
.. .. | | |.|. ..|. ||| |.|||. .| |.||.||.|...  ..|               ..||.| |        . | ...  | ....| |
HGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPE

VLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLS-------------------------------QEFTELLKVMIHPDPE
|....  . ||.|.... ... . .  .|. .. . ||.     . .| ....                               .|. ...| ....||.
VIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

RRPSAMALVKHSVL
.||.|. ...|  .
KRPTAEQILQHPWF
Kinase Wee1.AA S_TKc 299-569 22 2.2e-35 124.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 299-569
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNG--GSLADAISENYRIM-
.. |.|||.| ||.|.||... .| |.|||. |         ....||.  .    .| ..|... .. . ||. .  |||.|  |.| | | .. |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-SYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTH
 ..| | . . .. |. ..| |.||.  .| |.||.||....                       ||.| |  ...       |   ..| |||     .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------HIKICDFGLARQL---TTFCGTPWYMAPEVL----GY

LP-KADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVK-------HSVL
 . |.|. ..  ..   .  .|. .  ..   ... .        |.|. .... . . |||.||.|  . .       |  .
GKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Wee1.AA STE 299-569 19 1.1e-34 119.98 In-house 1-359 (359) Show / Hide 
Range on Protein: 299-569
Range on HMM: 1-359/359
Sequence Identity: 19% (74 aa)

FHELEKIGSGEFGSVFKCVKRL---------------DGCIYAIKRSKKPLAGS---------------VDEQNALREVYAHAVLGQ-HSHVVRYFSAWA
.  .||||.| ||.|.|....                 |.|.|||. ..    .                ..|. |.|.  .  . . | ..|.|. .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------DHMLIQNEYCNGGSLADAISENYRIM----------SYFKEAELKDLLLQVGRG-LRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDE
 .       |.  |  ||..|||| | | ..| .           ..|.| ...  . |. .| | |.||.  .| ||||.||..               
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------------

DDWASNKVMFKIGDLGHVTRISS---------------PQVEEGDSRF----LANEVLQE-----NYTHLPKADIFALALTVVCAAGAEPL----PRNGD
          |. | |. .....                .... ..       | ||.|      .  .  |.||  | .|..  |  .|     .    
---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTPWMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRA

QWHEIRQ--------------GRLPRIPQ-------------------VLSQEFTELLKVMIHPDPERRPSAMALVK--HSVL
 .. ..               |  |..|.                    .|.|| . ..     ||. ||.|  | |  |. .
MFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Wee1.AA Ciliate-E2 299-503 19 4.4e-30 100.44 In-house 1-282 (365) Show / Hide 
Range on Protein: 299-503
Range on HMM: 1-282/365
Sequence Identity: 19% (59 aa)

FHELEKIGSGEFGSVFKCVKRLDGC-----------------------IYAIKRS-KKPLAGSVDEQNALREVYAHA--VLGQ---------HSHVVRYF
.  ..|||.| ||||.|| ......                       |||.|.  |. .     |.. .||.       . .         | ......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKI-NEKNILEQLNHPNIIKMY

SAWA--EDDHMLIQNEYCNGGSLADAISENYRIM-------SYFKEAELKDLLLQVGR---------------GLRYIHSMS-LVHMDIKPSNIFISRTS
 ..    |... .  |||.||.| | | .|.           ||.| | |..  |. .               .|.|.||    .| ||||.||..    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

IPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEE-----------------------------------GDSRFLANEVLQ-ENYT-------HL
                     || |.|  .... .. ..                                   |   ..| |.|. ..|.       . 
--------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYD

PKADIFAL
 |.||..|
YKCDIWSL
Kinase Wee1.AA CAMK 304-435 20 1.6e-24 75.28 In-house 1-213 (425) Show / Hide 
Range on Protein: 304-435
Range on HMM: 1-213/425
Sequence Identity: 20% (44 aa)

KIGSGEFGSVFKCVKRLDG------------CIYAIKR-SKKPLAG-------------------------SVDEQNALREVYAHAVLG------QHSHV
..|.| || |..|. ....              .|||  .|| | .                          .|..| .||.  .  |       .| ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYFSAWAE-------------------DDHMLIQN---EYCNGG----SLADAISEN------------YRIMSYFKEAELKDLLLQVGRGLRYIHSMS
.. . ..                     |.|| .     ||| ||     | | | |.                 .|.|.| . .  |.  ...|.||. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

LVHMDIKPSNIFIS
 || |.|| || ..
IVHRDLKPENILLD
Kinase Wee1.AA Ciliate-E2-Unclassified 299-503 20 3e-24 81.03 In-house 1-256 (352) Show / Hide 
Range on Protein: 299-503
Range on HMM: 1-256/352
Sequence Identity: 20% (57 aa)

FHELEKIGSGEFGSVFKCVKRLDG--------CIYAIKRSKKPLAGSVDEQNALREVYAH---------AVLGQ------HSHVVRYFSAWAEDDHMLIQ
.. ...||.| ||.|.||... ..        . . |. .|. .    .. | . |.  .           . |      | ..|..| .   .... | 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

NEYCNGGSLADAISEN----------YRIMSY---FKEAELK-----DLLLQVGRGLRYIHSMS-LVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNK
 |||.||.| . |...          .. | .   | | . |     ... |.  || |.|.    .| ||||.||...                    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK----------------N

VMFKIGDLGHVTRISSPQVEE-------------------GDSRFL----ANEVLQE-NYTHL--PKADIFAL
   || |.|   .. ... ..                   |  ...    | ||||. || |    |.||..|
YYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSL
Kinase Wee1.AA PEK 299-371 34 3.8e-21 69.77 In-house 132-219 (655) Show / Hide 
Range on Protein: 299-371
Range on HMM: 132-219/655
Sequence Identity: 34% (31 aa)

FHELEKIGSGEF-GSVFKCVKRLDGCIYAIKRSKKPLAG---------------SVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDH
|.|....|.|.| |.|.|.  .|||| ||||| | . ..               .  ....|||| . | | .| ..|||..|| |...
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARL-NHPNIVRYHNAWIEKPE
Kinase Wee1.AA NEK 299-465 27 1.6e-20 69.26 In-house 1-168 (286) Show / Hide 
Range on Protein: 299-465
Range on HMM: 1-168/286
Sequence Identity: 27% (51 aa)

FHELEKIGSGEFGSVFKCVKRLDGCI-----YAIKRSKKPLAGSVDEQNAL-REVYAHAVLG--QHSHVVRYFSAWAEDD--HMLIQNEYCN-GGSLADA
. ...|||.| ||.|.|. .. || .     |..|. .     . . |||.  ||    .|   .| ..|.|. .. |..  .. |  |||. || |.. 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEV---RILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQK

---ISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM-----SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLG
   | ..     || | .  | . |   .|.|.|..       .| ||||.|||...  .                 .  ||||.|
IKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDY---------------HNVKIGDFG
Kinase Wee1.AA PEK 374-471 23 3.8e-16 52.02 In-house 360-483 (655) Show / Hide 
Range on Protein: 374-471
Range on HMM: 360-483/655
Sequence Identity: 23% (33 aa)

IQNEYCNGGSLADAISEN--------------------YRIMS---------------------YFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNI
|| |||....| | |..|                    | ||.                     .  . ...... |.  || ||||. ..| |.|||||
IQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNY-IMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNI

FISRTSI--PNAASEEGDEDDWASNKVMFKIGDLGHVTRIS
|... .   .                   |||| | .|...
FLDCDGQHHQ----------------MQVKIGDFGLATNHE
Kinase Wee1.AA PEK 299-370 34 8e-14 41.34 In-house 1-78 (758) Show / Hide 
Range on Protein: 299-370
Range on HMM: 1-78/758
Sequence Identity: 34% (27 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPL-------AGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDD
| . ...|.| ||.||.    .|.. |||||   |          .   .  .||| . | |  |.  ||||.|| | .
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAML-DHHNIVRYFNAWLETP
Kinase Wee1.AA PKR 299-366 44 1.6e-13 44.66 In-house 1-61 (272) Show / Hide 
Range on Protein: 299-366
Range on HMM: 1-61/272
Sequence Identity: 44% (30 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAW
|...|.|||| || |||   |.||  |.||| |        .  | .|| | | | .|  .|.| | |
FKDIEEIGSGGFGQVFKAKHRIDGKRYVIKRVK------YNNEKAEHEVQALAKL-DHVNIVHYHSCW
Kinase Wee1.AA TyrKc 299-569 18 5.7e-13 -13.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 299-569
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

FHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLG-QHSHVVRYFSAWAED-------DHMLIQNEYCNGGSLADAISE
 . ..|.|.|.|| |.|.. .      |.|  |.       ..  .||      || .| ..|| . .  ..       . ..|  ||. .|.| | . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLG---HVTRI-----SSPQVEEG---D
. .    .. ..| .  .|. .| .|.||. ..| |.   |. ...                       ||.| |    ..       |.         .
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG

SRF------LANEVLQEN-YTHLPKADIFALALTV--VCAAGAEPLPR-------NGDQWHEIRQGRLPRIPQV--------LSQEFTELLKVMIHPDPE
...      .| |..... .|.  | |...   .   ..  |..| |        | .  . ..||. ...|.          ..|  .. |   | |||
GKTMLPIRWMAPECINYGKFTT--KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

RRPSAMALVKHSVL
 ||.  ..  |. .
DRPTFSEI--HECF
Kinase Wee1.AA GCN2 299-373 36 7.3e-13 40.98 In-house 1-79 (511) Show / Hide 
Range on Protein: 299-373
Range on HMM: 1-79/511
Sequence Identity: 36% (29 aa)

FHELEKIGSGEFGSVFK-CVKRLDGCIYAIKRSKKPLAGSVDEQN--ALREVYAHAVLGQHSHVVRYFSAWAE--DDHML
| |.. .| |.||.| |    ..||..||||. . . ..  ..     .|||   . | .|.|||||. ||.|  |. |.
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRL-HHQHVVRYYQAWIEKCDEPMV
Kinase Wee1.AA PEK 371-473 29 8.6e-13 37.84 In-house 413-523 (758) Show / Hide 
Range on Protein: 371-473
Range on HMM: 413-523/758
Sequence Identity: 29% (34 aa)

HMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSI-------PNAASEEGDEDDWASNKVMFKIGD
.|.|| ..| . .| | .. . . |.   ... ... .|   |..||||. . | | |||||| |. |         | .|   .  |    ..  ||||
YMYIQMQLCRKETLKDWMRNR-CTMESRPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQII--KIGD

LGHVTRI----SSP
.| ||..    ..|
FGLVTDHTIVTPTP
Kinase Wee1.AA GCN2 374-434 42 8.1e-12 37.25 In-house 284-341 (511) Show / Hide 
Range on Protein: 374-434
Range on HMM: 284-341/511
Sequence Identity: 42% (26 aa)

IQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
|| ||| |..|...|...  .|    ..||. .. |.  || ||||.. .| |.||||||.
IQMEYCEGKTLRQYIDNHGWCM---DHDELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFL
Kinase Wee1.AA PKR 372-434 38 5e-09 28.32 In-house 96-156 (272) Show / Hide 
Range on Protein: 372-434
Range on HMM: 96-156/272
Sequence Identity: 38% (24 aa)

MLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
. || |.|  | |   . .  |  .    .   ||  |. .|  ||||  |.| |.||||||.
LFIQMEFCDKGTLEQWMRN--RRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPSNIFL
Kinase Wee1.AA NEK 526-569 31 7.4e-08 24.18 In-house 240-286 (286) Show / Hide 
Range on Protein: 526-569
Range on HMM: 240-286/286
Sequence Identity: 31% (15 aa)

IRQG-RLPRIPQV--LSQEFTELLKVMIHPDPERRPSAMALVKHSVL
|..|   |.||.    ||.  .|.  |...||| |||.  . ... .
IMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase Wee1.AA Pkinase_Tyr 299-424 21 7.1e-07 23.91 Pfam 1-134 (270) Show / Hide 
Range on Protein: 299-424
Range on HMM: 1-134/270
Sequence Identity: 21% (30 aa)

FHELEKIGSGEFGSVFKCVKR----LDGCIYAIKRSKKPLAGSVD--EQNALREVYAHAVLGQHSHVVRYFSAWA-EDDH--MLIQNEYCNGGSLADAIS
 . ..|.|.|.||.|.|.. .     ...  |.|   |. | . .   .  .||.     ||.| ..||.  .   ....  ..|  ||. .|.| |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EN--YRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
..   .    ..  .| .  .|. .|. | .|. ..|
KHREDKQP--LTMKDLLQMCWQIAKGMEYLESKNCIH
Kinase Wee1.AA PEK 526-569 21 5e-06 16.26 In-house 605-655 (655) Show / Hide 
Range on Protein: 526-569
Range on HMM: 605-655/655
Sequence Identity: 21% (11 aa)

IRQ------GRLP-RIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVL
.|.      | .|  . ..   .. .... |...||. ||||. . .|  .
LRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase Wee1.AA GCN2 541-569 31 8e-06 15.94 In-house 483-511 (511) Show / Hide 
Range on Protein: 541-569
Range on HMM: 483-511/511
Sequence Identity: 31% (9 aa)

EFTELLKVMIHPDPERRPSAMALVKHSVL
....... .. .|| .||||. | .|. |
DQQDMIRWCLNHDPQKRPSAQQLLQHEFL
Kinase Wee1.AA PEK 544-569 26 3.6e-05 11.88 In-house 733-758 (758) Show / Hide 
Range on Protein: 544-569
Range on HMM: 733-758/758
Sequence Identity: 26% (7 aa)

ELLKVMIHPDPERRPSAMALVKHSVL
|... |....|. ||.|  . .| . 
EFIQQMMSMNPDERPTADQISMHDFF
Kinase Wee1.AA CAMK 523-569 18 0.000173 9.59 In-house 356-425 (425) Show / Hide 
Range on Protein: 523-569
Range on HMM: 356-425/425
Sequence Identity: 18% (13 aa)

WHEIRQGRLPRIPQV-----------------------LSQEFTELLKVMIHPDPERRPSAMALVKHSVL
.. |..|.   .|                         .|||   |.. |  .|||.|...    .|  .
FEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Wee1.AA Ciliate-E2 534-569 26 0.000973 8.69 In-house 325-365 (365) Show / Hide 
Range on Protein: 534-569
Range on HMM: 325-365/365
Sequence Identity: 26% (11 aa)

IPQVLSQEFTELLKV----MIHPDPERRPS-AMALVKHSVL
... .|||   |.|     |.  ||| |.. .  . .|  .
SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Wee1.AA Ciliate-E2-Unclassified 534-569 20 0.101467 1.77 In-house 313-352 (352) Show / Hide 
Range on Protein: 534-569
Range on HMM: 313-352/352
Sequence Identity: 20% (8 aa)

IPQVLSQEFTELLK----VMIHPDPERRPSAMALVKHSVL
||. .|.|  ....     |.  .|. |...  . .|  .
IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF