Gene YANK1 (Human)

YANK1

Species: Human
Alias: STK32A, YANK1, MGC22688
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 5q34,

Classification

Group: AGC
Family: YANK

Sequence

Name Sequence Type Origin Length Description Download
YANK1.NA RNA Sugen Kinome 1816 None Fasta, JSON
YANK1.AA Protein Sugen Kinome 396 None Fasta, JSON
YANK1.kin_dom Protein Kinase Domain Sugen Kinome 259 None Fasta, JSON

Protein domain

Protein domains of YANK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YANK1.AA YANK 23-281 74 3e-229 767.89 In-house 1-261 (261) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-261/261
Sequence Identity: 74% (194 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEET
|.||||||||||||||||||.||||||||||||||||.||.||||||.||||||..|||||||||||||||||||||.||||||||||||||||||.|.|
FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQKMEHPFLVNLWYSFQDEEDMFMVCDLLLGGDLRYHLQQNVHFSEDT

VKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSSRK--GAGYSFAVDWWSLGVTAYELLRGR
|||.|||..|||.|||...|||||.|||||||||||||||||||||.||......|.|.|||||||||.|....  ..|||..||||||||.|||.|||.
VKLYICEMCMALEYLQEMHIIHRDIKPDNILLDEHGHVHITDFNIATMLKDNQRATSMSGTKPYMAPEIFQCYMDECKGYSYPVDWWSLGVCAYEMLRGW

RPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYM
|||||.|.|...||.|.|.|..|.|||.|.||||.||.|||...|..|.|.|.|.|..|||
RPYHIHSNTPIEEIYHMFSTNSVHYPSHWCQEMVDLLRKLLTVDPEHRISSLQDIQKHPYM
Kinase YANK1.AA AGC 23-281 26 2.3e-143 373.36 In-house 1-395 (395) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-395/395
Sequence Identity: 26% (105 aa)

FEILRAIGKGSFGKVCIVQKN------DTKKMYAMKYMNKQK-CVERN--EVRNVFKE------------LQIMQGLE----------HPFLVN-LWYSF
||.|. |||||||||. |.|.      ||.|.|||| ..|..  |...  .|...  |             .|.. .           |||.|. |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDEED--MFMVVDLLL---------GG-DLRYHLQ---QNVHFKEETVKLFICE-------LVMALDYLQN-QRIIHRD-MKPDNILLDEHGHVHITDFN
||..    ..| ...          || .| .|||   .. .| ||... ...|       .|.||.|| . . ||||| .||.||||||.||...||| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IAAMLPRE---------------------------------------------------TQITTMAG--TKPYMAPEMFSSRKGAGYSFAVDWWS--LGV
 . .....                                                    . .|. |  |  |||||..       |..|.||||  ||.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------YGKACDWWSFGLGC

TAYELLRGRRPYHIRSST-------SSKEIVHTFE------TTVVTYP----------SAWSQEMVSLLKKLLEPNPDQRFSQ---------LSDVQNFP
  ||.| |. |..  .         . .|. .  .      .  |..|          . .|.| ..|.||||...|..|             ....| |
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

YM
. 
WF
Kinase YANK1.AA S_TKc 23-281 31 7.2e-86 292.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLG--GDLRYHLQQNVH---
.|||| ||||.||||. .....|.. .|.| ..          ... .|.||..   ||..|.| ..||| ....|| ... |  |||. ..... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSSRKGAGYSF-AVDWWSLGVTA
   | | ... ...... ||.|. ...||||| ||.||||||  |. |.|| .|. |      ||. ||  |||||..      ||.. ..||||.|.. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCIL

YELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQ------NFPYM
||.| |. |..        ..  .|.  .       |.|. ....|.|. .|..| .     |      . |..
YEMLCGYPPFP--------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase YANK1.AA SGK 23-223 36 3.9e-80 247.06 In-house 1-225 (283) Show / Hide 
Range on Protein: 23-223
Range on HMM: 1-225/283
Sequence Identity: 36% (83 aa)

FEILRAIGKGSFGKVCIVQKNDT------------------KKMYAMKYMNKQKCV-------ERNEVRNVFKEL-QIMQGLEHPFLVNLWYSFQDEEDM
|..|  |||||||||  |.. |.                  .|.||||  .||  .        ..|....  |   |.. . |||.||| |.|| ..  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAA-MLPRETQITTMAGTKPYMAPEMFSSR
..| | . ||.. ||||   ||.|  ..    |.| ||.||  | ||.|| ||.|||||  ||. .|||  .      ..  .| .||  |.|||.    
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL---

KGAGYSFAVDWWSLGVTAYELLRGRRPY
...... .||||.||   ||.. |  |.
RKQPHDRTVDWWCLGCVLYEMMYGLPPF
Kinase YANK1.AA RSK 26-281 33 1.2e-76 260.9 In-house 1-278 (278) Show / Hide 
Range on Protein: 26-281
Range on HMM: 1-278/278
Sequence Identity: 33% (95 aa)

LRAIGKGSFGKVCIVQKN---DTKKMYAMKYMNKQKCVERNE-VRNVFKELQIMQGLE-HPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVH---
|.  |.|..||| ...|    ||.. ||||  .| | | |.  .| ...| .|..  . |||.|.| |.||.|.  ... ... ||.| .|||. .|   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDE---HGHVHITDFNIAAM-LPR-ETQITTMAGTKPYMAPEMFS--SRKGAGYSFAVDWWSLG
| |....  . |.|.|...|  | ||||| ||.|||.|.   .||. .|||  .    .. . .  |  .|  ||||||      .. |.. |.||||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHDKACDWWSLG

VTAYELLRGRRPYHIRSST-SSKEIVHTFETTV--VTYP--SAWSQEMVSLLKKLLEPNPDQRFS----QLSDVQNFPYM
|  ||.| |..|..  .   ..|||    ..    .| |  .  |||. .|..|.|. .| .| .     ...... |..
VLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase YANK1.AA Akt 23-224 41 3.8e-73 233.14 In-house 1-204 (264) Show / Hide 
Range on Protein: 23-224
Range on HMM: 1-204/264
Sequence Identity: 41% (86 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMY-AMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEE
|..|. .||||||||  |.|.||.|.| |||   |......|.|.... |  | |   |||.||| ||||...  ..| |   ||.| ||||.   |.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TVKLFICELVMALDYLQNQRIIHRD-MKPDNILLDEHGHVHITDFNIAAML-PRETQIT-TMAGTKPYMAPEMFSSRKGAGYSFAVDWWS-LGVTAYELL
. . ...|.. |...| .. || || .|| |||.|..||. .|||  . .    ....| |. ||  |.|||. .   | |.. |||||. ||.  ||..
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILN---GNGHTKAVDWWGSLGCVMYEMM

RGRRPYH
 || |..
CGRPPFY
Kinase YANK1.AA Pkinase 23-281 27 1.3e-71 249.07 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVF-KELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGG----DLRYHLQ--QN
..|.| ||.||||.|.. .. .| |..|.| ..|..  .  .....   |.|||. | ||. | |...|.|. .. || ... ||    ||  ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VHF--KEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHV----HITDFNIAAM--LPRETQITTMAGTKPYMAPEMFSSRKGAGYSFAVDWW
  |   |...| .. ... .|.|. ...|||||.||.|||.|..||.    .|.|| .|.   . . .  || .|| .|||||    |.| .|. .||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDMW

SLGVTAYELLRGRRPYHIR----SSTSSKEIVHTFETTVVTYPSAWS---------------------QEMVSLLKKLLEPNPDQRFSQLSDVQNFPYM
|.|.. ||.| || |.  .    .  . ....     . . ... |.                     .|. ...|..|...| .| .   .. . |..
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPWF
Kinase YANK1.AA Ciliate-E2 23-281 21 5.6e-68 232.15 In-house 1-365 (365) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

FEILRAIGKGSFGKVCIVQKNDTKKM-----------------------YAMKYMNKQKCVERNEVRNVF----------KELQIMQGLEHPFLVNLWYS
..... ||.|.||.|. ...  ..|.                       ||||.|.|..  . . . ...          .|..|.. | ||..... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DEEDMFMVVDLLLGGDLRYHLQQN-----------VHFKEETVK---------------LFICELVMALDYLQNQR-IIHRDMKPDNILLDEHGHV
||  |.. ...| ... ||||......|             |.|. .|                .|.... || || ..  ||||| ||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

HITDFNIAA----------------MLPRET-----------------QITTMAGTKPYMAPEMFSSRK------GAGYSFAVDWWSLGVTAYELLRGRR
 |.|| ..                 ...                    .. | .|| .|||||.... |      . ||....|.|||||. ||.| |..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYHIRSSTSSKEIVHTFETTVVTYPSA------------------WSQEMVSLLKK----LLEPNPDQRFSQLSDVQNFPYM
|.               .   . .|..                  ||||.  |.||    .|. .|..|..  ... | |..
PF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase YANK1.AA Ciliate-E2-Unclassified 23-281 24 1e-66 227.98 In-house 1-352 (352) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-352/352
Sequence Identity: 24% (86 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNV---------FKELQ-------------IMQGLEHPFLVNLWYSFQDEEDMFMVV
..|.. ||.|.||||. .|....|. ||||||.|.. . .. ..|.          ....             |.. . |||.|.. | |||.. ...| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DLLLGGDLRYHLQQN-----------------VHFKEETVK-----LFICELVMALDYLQNQ-RIIHRDMKPDNILLDEHG---HVHITDFNIAA-----
... ||||.......                  .| |. .|      .. ... .|.||  .  ||||| ||.|||.|. |   .. |.|| |.      
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

-----------MLPRETQITTMAGTKPYM----APEMFSSRKGAGYS----FAVDWWSLGVTAYELLRGRRPYHIRSSTS----------------SKEI
             ...  ..|..||  ||    |||..   .| .|.    ...|.||||| .||.| |..|.  .....                 ...
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL---QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

VHTFETTVVTYPS-----AWSQEMVSLLK----KLLEPNPDQRFSQLSDVQNFPYM
 .  .. .  .|       ||.|   ...    |.|. ||..|  ..... | |..
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFEQILNHPWF
Kinase YANK1.AA AktR 23-268 37 2.7e-66 226.56 In-house 1-251 (268) Show / Hide 
Range on Protein: 23-268
Range on HMM: 1-251/268
Sequence Identity: 37% (96 aa)

FEILRAIGKGSFGKVCIVQKN-DTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQ-GLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKE
|.... .||| ||||  |||. |..|.||||   |.| .|||  . .  | .||.    |||.|.| |.||..|  | . .   ||.| .||... .|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ETVKLFICELVMALDYLQNQ-RIIHRDMKPDNILLDEHGHVHITDFNIAA---MLPRETQITTMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYEL
|... .... . ||.|| ..  || ||.||.||||||.||| ||||  .    |  ..   ..  ||  ||||||       |. ..||||..|.  ||.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKK--KGHNKSVDWWAFGIFIYEM

LRGRRPYHIRSSTSSKEIVHTFETTV---VTYPSAWSQEMVSLLK-KLLEPNPDQR
. |  |     . . ..... . .     ..|||  |..  .|.. |||  || .|
VTGCPPF---YHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKR
Kinase YANK1.AA Delta 23-281 35 2e-62 213.7 In-house 1-259 (259) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-259/259
Sequence Identity: 35% (94 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQ-GLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEE
| ... .|||||||| ..   ...| ||.| . |.  .|  .|   . | ...  . |||||  |. .|| .| .| |.. | |||| ||.||  .|.|.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

TVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIA-AMLPRETQITTMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGR
  . . ||....| .| .. || ||.| ||.|||  ||..| || ..   . .|..  |  ||  |.|||.    ||  |...||||| ||  ||.| | 
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEII---KGQKYNHSVDWWSFGVLMYEMLIGQ

RPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPNPDQRFSQ----LSDVQNFPYM
 |.|        |. ..       ||   ..|  ..||||.| .|..|         |... .. 
SPFH---GEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase YANK1.AA RSK-Unclassified 23-165 42 4.2e-53 164.89 In-house 1-145 (283) Show / Hide 
Range on Protein: 23-165
Range on HMM: 1-145/283
Sequence Identity: 42% (61 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQ--QNVHFKE
|.  | ||.|.||||  |.| ||...|||| ..|.| . .| .. |  |  ||   .||| | | .||| .  .... .   |||.  |||      | |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

ETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDF
. |. .. | ..|| ||  . .| ||.|||||.|.  |||  |||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDF
Kinase YANK1.AA RSK-Unclassified 182-268 39 4.1e-17 49.8 In-house 184-266 (283) Show / Hide 
Range on Protein: 182-268
Range on HMM: 184-266/283
Sequence Identity: 39% (35 aa)

GTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYP--SAWSQEMVSLLKKLLEPNPDQR
||  |.||||    .. |   ||||| ||.  ||.| |  ||       . |.    |.  |  |  |  |..  .|.||||. ||  |
GTEEYLAPEMI---RRCGHTKAVDWWTLGIVMYEMLFGCPPYY---GNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKR
Kinase YANK1.AA TyrKc 23-278 21 2.8e-15 24.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-278
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGL--EHPFLVNLWYSFQDE-------EDMFMVVDLLLGGDLRYHLQ
 . .. .| | ||.|.  . .    . | | ... .      ..   .|..||  |  .|| .|.|     ..       | ...|. .  .|||. .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNVH-FKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRE------TQITTMA---GTKP-----YMAPEMFSSRKGA
 . . .. ..   |        .||  ...||||    |.|..| ..| |.||  .  .  .      ..  ...   |.|       |||| .  .|  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK--

GYSFAVDWWSLGVTAYELL-RGRRPYHI---RSSTSSKEIVHTFETT-VVTYPSA--------WSQEMVSLLKKLLEPNPDQR--FSQLSDVQNF
 .... | || ||. .|.. .|  ||     .   | .|...  ..      |           ..|| .. |.  . .|..|  ||..  .. |
-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase YANK1.AA Pkinase_Tyr 23-223 23 1e-12 43.72 Pfam 1-216 (270) Show / Hide 
Range on Protein: 23-223
Range on HMM: 1-216/270
Sequence Identity: 23% (53 aa)

FEILRAIGKGSFGKVCIVQKN----DTKKMYAMKYMNKQKCVERN-EVRNVFKELQIMQGL-EHPFLVNLWYSFQ-DEED--MFMVVDLLLGGDLRYHLQ
 .... .|.|.||.|.    .    .||   | | . |... ...   .  ..|..||  |  || .|.|      ..|   ...|. .  .|||. .|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----NVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAML-PRETQITTMAG----TKPYMAPEMFSSRKGAGYSFAV
.    . ... ..   .  .  ....|| ....||||    |.|..| ..| |.||  |  . . ..  ....|      . |||| .. .|   .. . 
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK---FTTKS

DWWSLGVTAYELLR-GRRP-Y
| || ||. .|..  |. | |
DVWSFGVLMWEIFTYGEQPTY
Kinase YANK1.AA Akt 243-268 32 0.000478 8.74 In-house 220-247 (264) Show / Hide 
Range on Protein: 243-268
Range on HMM: 220-247/264
Sequence Identity: 32% (9 aa)

VTYP--SAWSQEMVSLLKKLLEPNPDQR
| .|  ...|.|  .|...||. .|..|
VKFPDKDWISPECKDLISGLLNKDPKKR