Gene DDB0220700 (Slime mold)

DDB0220700

Species: Slime mold
Alias: DdisK006, DDB0220700
External Links: DictyBase Link ,
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
DDB0220700.AA Protein None 462 None Fasta, JSON
DDB0220700.kin_dom Protein Kinase Domain None 295 None Fasta, JSON

Protein domain

Protein domains of DDB0220700.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0220700.AA MAST 64-358 45 4.3e-208 642.68 In-house 1-337 (337) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-337/337
Sequence Identity: 45% (160 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNFIVELFSSFQT--DKKLFFVMEFLNGGDCASLLRSFNNNMP
|.|.|.||||..|.|||...|.|....|.|||...|||.|..||||..|..||..|...|.|..|.||||  .|.|..|||...|||||||||...|.||
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVDESCNIKILK--------NSFTLYNTNNNNTTE-------------
|...|..||....||||||..||.||||||||.||||||||||.||||||..|.|...|... .        |.|..|....|....             
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

------------------------NQKILGTPYYIPPEVILGKG-YGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHK
                        |....|||.||.||||||.| |||..||||.|||.||||.|.|||..|.|.|              .||..|.||.
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEE--------------MIFQNIINHD

KKLYFPKK--------LYPVAIDLIEKLLDPNPSVRLGANGVDEVKCHPFF
.....|..        ..|.|.|||.|||.|||..||||||.||.|.||||
REIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase DDB0220700.AA MAST 64-358 44 1.5e-188 613.32 In-house 1-334 (334) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-334/334
Sequence Identity: 44% (156 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNFIVELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNNMPED
|.| |.||||..|||||...| |....|.|||||||.|.|.|||||..|..||..|...|.|..|.||||...|..|||...||||||||.... ...|.
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG-YFDEW

LTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVDESCNIKIL-------KNSFTLYNTNNNNTTE----------------
..|..||....||||||.|||.||||||||.||||||||||.||||||..|.|........       .||.. .|.|......                
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQI

---------------------NQKILGTPYYIPPEVILGKG-YGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHK---
                     |....|||.||.||||||.| .||..||||.|||.||||.|.|||..|.|.               .||..|.|..   
QQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPE---------------EIFQNILNRNCNE

KKLYFP------KKLYPVAIDLIEKLLDPNPSVRLGAN-GVDEVKCHPFF
......      ....|.|.|||||||.|.|..||||| |.||||.||||
IEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase DDB0220700.AA AGC 64-358 31 2.7e-163 426.05 In-house 1-395 (395) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-395/395
Sequence Identity: 31% (132 aa)

FNFLKVISKGGFGKVYLAENK------ITKKTVAIKVIKKSD-TIKKM--MVDQVNIE------------KTILSNYK----------CNFIVE-LFSSF
|.|||||.||.||||||.. |       |.|  |.||.||..  ..|.  ||.....|            . ||....          . |||  |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTDKK--LFFVME----FLN----GGDCASLLRSFNN----NMPEDLTKNIIAQ-------IIICLEYLHN-HGIIHRD-LKPDNILIDSNGHIKLADFG
|....  |.||||    ..|    ||.| ..|. ..      ..|. .. ..|.       |. .|||||. .|||||| |||.|||.|..|||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKFDFVDE-------SCNIKILKNSFTLYNTNNN--------------------------------NTTENQKILG--TPYYIPPEVILGKGYGKTIDW
|.|    |.       |       |  .....  |                                ..  .. . |  || |..||..    |||. ||
LCKEGMNDGEKGQQSQS-------N--MKFHW-HNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDW

WS--LGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVR-------IIFNKITNH----KKKLYFP----------KKLYPVAIDLIEKLLDPNPSVRL
||  ||...||.|.|||||. |.|.| .           |        .|.|| |.    ..|. ||          ... | | |||.||| ..|. ||
WSFGLGCLMYEMLTGYPPFYGDNPQE-N-----------RHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRL

GAN-------GVDEVKCHPFF
|..       |..|.| ||.|
GCGGNDFGDKGAEEIKNHPWF
Kinase DDB0220700.AA NDR 64-358 31 2.5e-107 332.16 In-house 1-350 (350) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-350/350
Sequence Identity: 31% (116 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYK--CNFIVELFSSFQTDKKLFFVMEFLNGGDCAS---LLRSFNN
| ..|.|.||.||.|.|.  | |.. .|.|...||. ..|  |..|  |. |..  .  ....|.|. ||| .. |..|||.. |||  .   ||  . .
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKM-D

NMPEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSKF----------------------------------DFVDESCNIKIL
  .||...  || .. ..|..|. |.||||.||||.|||. ||||| ||||..                                   ... ......  
IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNW

KNSFTLYNT-----------------NNNNTTENQ-----KILGTPYYIPPEVILG-KGYGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDE
.....  ..                 ||... .|.     .. ||| |..|||... .||..|.|||||| |.||.|.|||||                 
NSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFC---------------S

KNVRIIFNKITNHKKKL-----YFP--KKLYPVAIDLIEKLLDPNPSVRLGANG--VDEVKCHPFF
 ... .. || | |. .      ||   .| | | |||..|. |.|. |||..|  |||.| ||||
DTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase DDB0220700.AA S_TKc 64-358 33 7.6e-104 352.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-231/231
Sequence Identity: 33% (104 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNFIVELFSSFQTDKKLFFVMEFLNG--GDCASLLRSFNNN--
. .|..| ||.|||||.. .| |.. ||||.||          ...  |  ||.. .. .|| |. .||. ..|..|||...|  ||  ..... . .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MPEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVDESCNIKILKNSFTLYNTNNNNTTENQKILGTPYYIPPEVI
   .||  .. ...||.  |||.|.||||||||||.|||.|.  |||..||||...                               . |||.|..|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------TTFCGTPWYMAPEVL

LGKGYGK-TIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFPKKLYPVAIDLIEKLLDPNPSVRLGANGVDE----
   ||||  .||||.|.||||.| |||||.                 ..  .|.||              | |.|.|.|.|. .|. |..|  . .    
---GYGKCKCDWWSCGCILYEMLCGYPPFP-----------------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD

VKCHPFF
.||||.|
IKCHPWF
Kinase DDB0220700.AA AktR 64-358 36 1.1e-93 317.54 In-house 1-268 (268) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-268/268
Sequence Identity: 36% (112 aa)

FNFLKVISKGGFGKVYLAENK-ITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILS-NYKCNFIVELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNNMP
| ..|.. ||.||||||.. |  ..| .|.|.|||.. |.. . ...  |..|.    . .||| |. .|||..||||.||.  ||.  . |. ... . 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLK-KKKKFS

EDLTKNIIAQIIICLEYLHNH-GIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVDESCNIKILKNSFTLYNTNNNNTTENQKILGTPYYIPPEVILG-K
|. .. ..|||...|||||.|  || |||||.|||.|..||.|..||||||                       . .. ......||| |..||.|.  |
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKK

GYGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHK-KKLYFPKKLYPVAIDLIE-KLLDPNPSVRLG--ANGVDEVKCH
|..|..|||..|| .|| ..|.|||.                || ...| || ..  .|  .|... . . |||. |||. ||  |||  .|| .|.| |
GHNKSVDWWAFGIFIYEMVTGCPPFYH---------------KNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSH

PFF
|.|
PWF
Kinase DDB0220700.AA Ciliate-E2 64-358 25 4.3e-84 285.68 In-house 1-365 (365) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-365/365
Sequence Identity: 25% (103 aa)

FNFLKVISKGGFGKVYLAEN-----------------------KITKKTVAIKVIKKSDTIKKMMVDQVN----------IEKTILSNYKCNFIVELFSS
..|.|.| .|.||.||....                       | ..| .|.|..||.. . ........          .|| ||.. ....|.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TDKKLFFVMEFLNGGDCASLLR----SFNNNMP------EDLTKNIIAQII---------------ICLEYLHNHG-IIHRDLKPDNILIDSNGHI
||  .|.....|||...|||  ....    ..|.. .      |   |.|..||.                .|||||. . |||||.||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGLSKFDFVDESCNIKILKNSFTLYNTNNNNTTENQK-------------ILGTPYYIPPEVILGKG---------YGKTIDWWSLGIILYEFLIG
|..||||||. . |...|. . |.   .|   .|.|.  .              |.|||.| .||.. ||.         |.. .|.||||.||||.| |
KIIDFGLSKK-YDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFP------------------KKLYPVAIDLIEK----LLDPNPSVRLGANGVDEVKCHPFF
.|||                          . ....|. ||                  ||. . ..||| |    .|. .|. |..  | .... ||.|
KPPF-------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase DDB0220700.AA Pkinase 64-358 29 2.8e-83 287.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-293/293
Sequence Identity: 29% (96 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVN-IEKTILSNYKCNFIVELFSSFQTDKKLFFVMEFLNGG----DCASLLR-SFN
. ....| .|.||.||.. .| | |.||.|.|||... ... .  ..  |  |. . .. .||.|. .|...... .|||...||    | ..... . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNM--PEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHI----KLADFGLSK-FDFVDESCNIKILKNSFTLYNTNNNNTTENQKILGTPYY
...  .|.  |... ||.  |||.|..|||||||||.|||||.||||    |..||||.| ||                     . | . .. . |||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------------Y-NNS-MTTFCGTPWY

IPPEVIL-GKGYGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFPKKLY-------------------PVAID
..||||. |..||. .|.||.|.||||.| |.|||...  ..        .  . . ....|   . .  .|..                     . ..|
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WH-------DN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LIEKLLDPNPSVRLGANGVDEVKCHPFF
.|...|...|. |..    .....||.|
FIKWCLCKDPKKRPT---AEQILQHPWF
Kinase DDB0220700.AA RSK 67-358 33 2.8e-79 269.71 In-house 1-278 (278) Show / Hide 
Range on Protein: 67-358
Range on HMM: 1-278/278
Sequence Identity: 33% (105 aa)

LKVISKGGFGKVYLAENKI---TKKTVAIKVIKKSDTIKKMM-VDQVNIEKTILSNYK-CNFIVELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNN--
|||  .||.|||.|   ..   |..  | ||.||.  ...   .  .  | .||. .. . |||.|. .|||..||. .||...||.    |.       
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

MPEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDS---NGHIKLADFGLSKFDFVDESCNIKILKNSFTLYNTNNNNTTENQKILGTPYYIPPEVI
. ||  . ..|.|.  .|.|| .|||||||||.||| |.   .||||| |||..|                      .....   ..  .|  |..||..
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF--------------------RCDHNQWTMTFCYTIEYMAPEML

L----GKGYGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFP--KKLYPVAIDLIEKLLDPNPSVRLG--ANG
     ..|..|  ||||||...|| | |.||||   ||           .|   |...| . |  | .|  ..| . | ||| |.|  .|. |||   ..
KRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG--PND----------NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQD

VDEVKCHPFF
..|.| ||.|
AEEIKQHPWF
Kinase DDB0220700.AA SGK 64-211 41 2.7e-60 184.71 In-house 1-173 (283) Show / Hide 
Range on Protein: 64-211
Range on HMM: 1-173/283
Sequence Identity: 41% (72 aa)

FNFLKVISKGGFGKVYLAENKIT------------------KKTVAIKVIKKSDTI-------KKMMVDQVNIEK-TILSNYKCNFIVELFSSFQTDKKL
| ||||| ||.|||||... | .                  .|  |.||..|   |       ||  .  . .|. .||.| |  ||| |  .|||..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFVMEFLNGGDCASLLRSFNNNMPEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSK
.|||...|||.  . |.   .  |||  .   |.|.  |||||   ||.|||||.||| |. ||..| ||||.|
YFVMDYVNGGEMFYHLQR-EKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCK
Kinase DDB0220700.AA Akt 64-211 47 2.3e-58 185.15 In-house 1-149 (264) Show / Hide 
Range on Protein: 64-211
Range on HMM: 1-149/264
Sequence Identity: 47% (71 aa)

FNFLKVISKGGFGKVYLAENKITKKTV-AIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNFIVELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNNMPE
|.||||. || ||||.|.. | |.|   |.||.||.  |.|  | ..  |. || .....||| |  |||| .||.|||.. |||.  ..|.   . ..|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQR-KRRFSE

DLTKNIIAQIIICLEYLHNHGIIHRD-LKPDNILIDSNGHIKLADFGLSK
| ..  .|.||  .|.||...|| || ||| |||.|..|||.|.||||.|
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK
Kinase DDB0220700.AA PKA 64-211 42 2.3e-49 170.32 In-house 1-149 (263) Show / Hide 
Range on Protein: 64-211
Range on HMM: 1-149/263
Sequence Identity: 42% (64 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCNFIV-ELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNNMPE
|...... .| ||.|.|. .|.... .|.|..||.. ..   |. |. ||.||.| |  ||| .. ..||.|..|..|||. .||.  | ||  .   ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRK-SGRFSN

DLTKNIIA-QIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSK
. .| ..| ||.  |||||.. ||.||||| |||||.|||||..||| .|
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK
Kinase DDB0220700.AA SGK 246-358 35 2.6e-36 109.3 In-house 187-283 (283) Show / Hide 
Range on Protein: 246-358
Range on HMM: 187-283/283
Sequence Identity: 35% (41 aa)

GTPYYIPPEVILGKGYGKTIDWWSLGIILYEFLIGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNHKKKLYFPKKLYPVAIDLIEKLLDPNPSVRLG
||| |  |||........| |||.||..|||...| |||                 .|. . . .| |  ..| .|.   . | |||. ||  .|. |||
GTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFY---------------SRNKQQMYDNIIN--QPLQIPPQMSNDAWDLIQGLLQKDPKKRLG

AN-GVDEVKCHPFF
.. .  |.| ||||
TKRDFMEIKNHPFF
Kinase DDB0220700.AA PKA 246-358 39 6.6e-30 105.69 In-house 160-263 (263) Show / Hide 
Range on Protein: 246-358
Range on HMM: 160-263/263
Sequence Identity: 39% (48 aa)

GTPYYIPPEVILGK-GYGKTIDWWSLGIILYEFLIGYPPFQED--EPNESINPKSDNDEKNVRIIFNKITNHKKKLYFPKKLYPVA---IDLIEKLLDPN
||| |..||.|..| |.|| .|||.|||. ||.| ||||| ..  .|..               |..|| |.  |. ||  . . |    |||.||| ..
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQ---------------IYEKICNG--KIKFPRHFDSDANYFKDLIKKLLQVD

PSVRLG--ANGVDEVKCHPFF
.. |.|   |||. .| |..|
LTKRYGNMKNGVNDIKNHKWF
Kinase DDB0220700.AA Akt 246-284 50 3.8e-19 57.79 In-house 164-203 (264) Show / Hide 
Range on Protein: 246-284
Range on HMM: 164-203/264
Sequence Identity: 50% (20 aa)

GTPYYIPPEVILGKGYGKTIDWWS-LGIILYEFLIGYPPF
||| |..||...|.|..|. |||. ||...||.. | |||
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF
Kinase DDB0220700.AA TyrKc 64-358 19 2.2e-13 -6.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 64-358
Range on HMM: 1-280/280
Sequence Identity: 19% (63 aa)

FNFLKVISKGGFGKVYLAENKITKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNY--KCNFIVELFSSFQTD-------KKLFFVMEFLNGGDCASLLR
  ..|..  | ||.||... |    .||.|..|..   .... .    |  |....  .   || |.    ..       . |. |||.  .||. . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMR----EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SFNNNMPEDLTKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSKFDFVD-ESCNIKILKNSFTLYNTNNNNTTE--NQKILGTPYYI
.  .. . .   ..  ||    |||| ...|||||   |.|...|...| .|||||..   | ..             ..    ..|  . | .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----------ESKDYYRKKEHKGGKTMLPIRWM

PPEVILGKGYGKTIDWWSLGIILYEFL-IGYPPFQEDEPNESINPKSDNDEKNVRIIFNKITNH---KKKLY--------FPKKLYPVAIDLIEKLLDPN
.||.|  . .    | || |. ..| .  | .|  ... .           .. . ..... .    ..  .         |...|    .....  . .
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY----QIMKQCWHED

PSVRLGANGVDEVKCHPFF
|. |   . .     | .|
PEDRPTFSEI-----HECF
Kinase DDB0220700.AA Akt 316-358 38 6.8e-13 37.46 In-house 218-264 (264) Show / Hide 
Range on Protein: 316-358
Range on HMM: 218-264/264
Sequence Identity: 38% (18 aa)

KKLYFP--KKLYPVAIDLIEKLLDPNPSVRLG--ANGVDEVKCHPFF
... ||  ... | . |||..||  .|. |||   |...|.| ||.|
QPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase DDB0220700.AA Pkinase_Tyr 176-211 44 4.1e-10 34.86 Pfam 124-159 (270) Show / Hide 
Range on Protein: 176-211
Range on HMM: 124-159/270
Sequence Identity: 44% (16 aa)

LEYLHNHGIIHRDLKPDNILIDSNGHIKLADFGLSK
.|||.....|||||   |.|...|...| .||||..
MEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase DDB0220700.AA Pkinase_Tyr 64-100 34 0.008308 10.13 Pfam 1-41 (270) Show / Hide 
Range on Protein: 64-100
Range on HMM: 1-41/270
Sequence Identity: 34% (14 aa)

FNFLKVISKGGFGKVYLAENK----ITKKTVAIKVIKKSDT
  |.|.. .| ||.||... |     || .||.|..| . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAM