Gene pk3 (Slime mold)
pk3
Group:
AGC
Family:
AGC-Unique
Sequence
Protein domains of pk3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PH_Akt_basal | pk3.AA | PH_Akt_basal | 36-120 | 27 | 2.2e-36 | 127.17 | In-house | 1-90 (90) | Show / Hide |
Range on Protein: 36-120 Range on HMM: 1-90/90 Sequence Identity: 27% (25 aa) VIKVNAYGKRQQRTLAVSSLGVSNLNGQ---SCQWFVRNSDVYSIEQDPTDSHKFSLTFLHRYH--FEAETPEQAKSIISEFKRLGVGSP |||.|.|.|||.|.|...|..|.|.... |..|.......|.|.|..|....|.......|. .......|...||....|. ... VIKYNRYNKRQERNLMITSKHVYNCKPNKKHSIKWCIPLQKIYGIHQSTTEGCEFVIHVPDEYDYRYCMHSEDQRQCIIMVLCRAYCCYC |
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| Kinase | pk3.AA | AGC-Unique | 498-763 | 67 | 3.4e-226 | 757.74 | In-house | 1-270 (270) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-270/270 Sequence Identity: 67% (183 aa) FELLKVLGVGSFGRVYLVRRK---DTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQKAGKFP ||.||..||||.||||.|||| ||.|||||||.||.||.|.||..|.|||.|.|.||.|||..|.|..|||.|.|||||||||||..|||.|.|..|. FEILKHIGVGSYGRVYAVRRKNGCDTEKFYAMKVMNKRDMSKHKQMVHHNTEWMILTTMHHPFFMRMHYSFQNKDHLFMCMDYVPGGDMFHHMQNAECFI EELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGHGKAADWWSVGIL ||.|.|||.|||||.||||.|.||.|||||||||.|..|||..||.||||.|..||....||||||||||||||..|.||||.|...|||..|||||||. EESAHFYICEVICSIHYLHENHIIHRDIKPENILIDNDGHIMITDYGLSKTGCDSVDAIQNGGEGGFATTFCGTRHYMAPEIHTEKKHGKSCDWWSVGIT LFEMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKRLG-STQGFEEISSHPFF ...|.|.||||.||||||||.||||...|||||||.|.||...||.|.|||.||| |.||||||.||..| YCDMRTDRSPFDASNRNDMYDSMIQKRPRMPMFLSPDEQDFVNKLIVRDPNQRLGNSPQGFEEIKSHDMF |
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| Kinase | pk3.AA | AGC | 498-763 | 37 | 6.9e-200 | 522.88 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-395/395 Sequence Identity: 37% (148 aa) FELLKVLGVGSFGRVYLVRRK------DTGKFYAMKVLNKKD---MLKKKQIAHTNTE------------KMVLSTMD----------HPFIVR-LHFAF ||.|||.| ||||.|||||.| ||||.||||||.||. ..||....||.|| . .|.... |||||. ||..| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QNEDF--LFMCMDYVP---------GG-ELFHHLQ---KAGKFPEELAKFYIAE-------VICSLHYLHS-NNIIYRD-IKPENILLDEEGHIKLTDFG |..| |...|.|.| || |||.||| | |.|.|| |.||.|| ... |.|||| ..||.|| .|||||||||.||||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSKSGITSV------------------------------------------VGSKNGGEGGFATTFCG--TPEYLAPEIITGAGHGKAADWWS--VGILL |.| |... ... ... ..|||| ||||.||||. .|||.|||| .|.|. LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM FEMLTGRSPFLASN----------RNDMYKSMI------QGNLRMP----------MFLSSDAQDLLEKLLVPDPNKRLGSTQ------GFEEISSHPFF .|||||..|| . | ...|... . . ....| ..|..|.||..|||..||.||||. . |.||| .||.| YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | pk3.AA | Akt | 498-763 | 49 | 1.1e-160 | 517.42 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-264/264 Sequence Identity: 49% (135 aa) FELLKVLGVGSFGRVYLVRRKDTGKFY-AMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQKAGKFPEE |..||||| ||||.|.||. |||.|.| ||||| |. ..|.|..|| ||...| ...||||| ||..||..| |...|||..||||| |||....|.|. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED LAKFYIAEVICSLHYLHSNNIIYRD-IKPENILLDEEGHIKLTDFGLSKSG-ITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGHGKAADWWS-VGI |.||.||.|. . .|||.|||||| ||||||.|..|||.||||||.| . |. .. ..|||||||||||||. | ||.||.|||. .|. RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIK---------DHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGC LLFEMLTGRSPFLASNRNDMYKSMIQGNLRMP--MFLSSDAQDLLEKLLVPDPNKRLG-STQGFEEISSHPFF ...||..|| || . .. |.| ......| ..| ...||...|| ||.|||| .. .|| .||.| VMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | pk3.AA | SGK | 498-763 | 47 | 2.5e-156 | 486.62 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-283/283 Sequence Identity: 47% (139 aa) FELLKVLGVGSFGRVYLVRRKDT------------------GKFYAMKVLNKKDML-------KKKQIAHTNTEK-MVLSTMDHPFIVRLHFAFQNEDFL |..|||.| ||||.||.|..||. .||||||||.|. . |||. |. .|. .|. | ||||| ||.|||... | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL FMCMDYVPGGELFHHLQKAGKFPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEY .. |||| |||.| |||....||| |.|| ||..| | |||| .||||| |||||||| .||..||||||.| || . . .|||||||| YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIK---------TNDTTFTFCGTPEY LAPEIITGAGHGKAADWWSVGILLFEMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKRLGSTQGFEEISSHPFF ||||.. ...|... |||. |..|.||..| || |.. || | . |..| . |.|| ||.. || || ||||. ..|.|| .|||| LAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | pk3.AA | AktR | 498-763 | 49 | 3.1e-139 | 468.84 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-268/268 Sequence Identity: 49% (136 aa) FELLKVLGVGSFGRVYLVRRK-DTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLS-TMDHPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQKAGKFPE |...|.|| | ||.||||..| |..|.||||.. ||.. ...|. || ||. .. ..|||||.||..||... || .|.|.||||||.||.| .|| | FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE ELAKFYIAEVICSLHYLHSN-NIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGG--EGGFATTFCGTPEYLAPEIITG-AGHGKAADWWSV | |.||.|... | |||.. ||||||.|||||||||.||.|.||||||| . . .|..|||||||.|||.|| ||.|..|||.. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAF GILLFEMLTGRSPFLASNRNDMYKSMIQGN---LRMPMFLSSDAQDLLE-KLLVPDPNKRLG-STQGFEEISSHPFF ||...||.|| || ..|.|.|... . . |. .|| ..||.. ||| .|||||| .. |.||| |||.| GIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | pk3.AA | RSK-Unclassified | 498-763 | 42 | 1.7e-133 | 421.9 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-283/283 Sequence Identity: 42% (121 aa) FELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQ--KAGKFPE |. . .| |.||.|||||.||| . ||||||.|. |.... | ||. ...| .|||||.| ..|| .| |..||.| .||..| ||| | .| | FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE ELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSG------------ITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGHG ....||..||. | ||| .|||| ||.||.|. |||..||||.||. . | | .| . |||| ||||||.| . ||. DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT KAADWWSVGILLFEMLTGRSPFLASNRNDMYKSMIQGNLRMP--MFLSSDAQDLLEKLLVPDPNKRLGSTQG-FEEISSHPFF || ||| ||...||| | |. . |.| ... ......| ..| ...||. ||| | ||||. .| ..| |||| KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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| Kinase | pk3.AA | RSK | 501-763 | 46 | 8.3e-127 | 427.57 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 501-763 Range on HMM: 1-278/278 Sequence Identity: 46% (132 aa) LKVLGVGSFGRVYLVRRK---DTGKFYAMKVLNKKDMLKKKQ-IAHTNTEKMVLSTMD-HPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQKAGK--- ||||| |..| |.|.|.. |||. ||||||.|. . ... ..|| || .|.. |||||.|| ||| |. |...|.|..||||| |||| . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDE---EGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIIT----GAGHGKA | |. |.||.||... . .||. ||.||.||||||.|. ||||||||||..| . . ... . |||.| ||.|||... . ||.|| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF--------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKA ADWWSVGILLFEMLTGRSPFLA---SNRNDMYKSMIQGN--LRMP--MFLSSDAQDLLEKLLVPDPNKRLGS-TQGFEEISSHPFF .|||| |.|..|||||..|| . .||.. | . .|. |.|| .|| .|.||. |.| ||.||||. |. ||| .||.| CDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | pk3.AA | PKC | 498-763 | 44 | 1.5e-117 | 382.65 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-262/262 Sequence Identity: 44% (120 aa) FELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLST-MDHPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQKAGKFPEE |..||||| |||| | |..||.| ..||.||| | .. . | ||| ||.. ||| . || || .| || | || || | .| |....|.|| FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE LAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGHGKAADWWSVGILLF |.|| ||.|| |..||...||||| | .|.|||.|||||..|||..| ... .| ..||||||.|.||||. . ||. |||. |.|.. HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMW---------NGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMY EMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKRLGS--TQ--GFEEISSHPFF ||. |.||| . . .. .| . | . | || .| ....... .|.||||. .| |...| .|||| EMMAGQSPFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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| Kinase | pk3.AA | S_TKc | 498-763 | 38 | 6.2e-117 | 395.69 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-231/231 Sequence Identity: 38% (107 aa) FELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPG--GELFHHLQKAGK--- .|.|...| |.||.||..| |.||. .|.|... |. | .|. .||.||.|. .||. |.|.|.|.|..| |.||....| |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGHGK-AADW ||| |.||.....| | |.||..||.||.||||||||| |||..||||.. |||||||.|.|||.. |.|| ..|| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL---GYGKCKCDW WSVGILLFEMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKRLGSTQGFE---EISSHPFF ||.|..|.|||.|. || . . |.| . |..| |...|.|. ||.||.. . .. .| .||.| WSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | pk3.AA | p70 | 498-763 | 42 | 3.6e-113 | 382.26 | In-house | 1-299 (299) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-299/299 Sequence Identity: 42% (126 aa) FELLKVLGVGSFGRVYLVRRKD---TGKFYAMKVLNKKDMLK-KKQIAHTN-------------------------TEKMVLSTMDHPFIVRLHFAFQNE |||||||| | .| |..|| ||| |||||| | . | ||| | .|.. ||||. ||.||| . FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN DFLFMCMDYVPGGELFHHLQKAGKFPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFAT-TFCG |. .| .||||| || . | ..|. |.|| .|.||.| .||. ||||| ||||..|.. ||..||||||.| | . | || |||| GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG TPEYLAPEIITGAGHGKAADWWSVGILLFEMLTGRSPFLASNRNDMYKSMIQGN--LRMPMFLSSDAQDLLEKLLVPDPNKRLG-STQGFEEISSHPFF |.|| ||||... ||..| |||| |.|.. |||| || ..|| . .. ..| |..| |. .. ||. ||| .| .|.| . ..| .|||| TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF |
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| Kinase | pk3.AA | Pkinase | 498-763 | 32 | 1.4e-103 | 355.21 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 498-763 Range on HMM: 1-293/293 Sequence Identity: 32% (101 aa) FELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTN-TEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGG----ELFHHLQ--KA .......| ||||.||. ..|.||| .|.|...|.. ..|...|.. .| .. ..||.||||. .|...| . |.|.|..|| .||.... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GKF--PEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHI----KLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIIT-GAGHG |.| .|. .|||. .... | |.||..||.||.||||||.|..||| |..||||.| .. .|||||||.|.|||.| | ..| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG KAADWWSVGILLFEMLTGRSPFLAS------NRNDMYKSMIQGNLRMPMFLS---------------------SDAQDLLEKLLVPDPNKRLGSTQGFEE ...|.||.|..|.|||.|| || . . . |.. .. |. . . . ....|.....| .||.||.. .|. PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT----AEQ ISSHPFF | ||.| ILQHPWF |
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| Kinase | pk3.AA | PKA | 498-644 | 53 | 4.1e-85 | 289.08 | In-house | 107-255 (263) | Show / Hide |
Range on Protein: 498-644 Range on HMM: 107-255/263 Sequence Identity: 53% (79 aa) FELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVR-LHFAFQNEDFLFMCMDYVPGGELFHHLQKAGKFPEE ||....|| ||||||.|.| |..|..||||.|.| . . ||. |...|| .|. ..|||||. . . ||....|.| |.||||||.|..|.| |.|.. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP LAKFYIA-EVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSK ||||.| .... | |||| |||||| ||||||.|..||||.|||| .| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK |
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| Kinase | pk3.AA | PKA | 664-763 | 44 | 3.3e-48 | 166.46 | In-house | 157-263 (263) | Show / Hide |
Range on Protein: 664-763 Range on HMM: 157-263/263 Sequence Identity: 44% (48 aa) TFCGTPEYLAPEIITGA-GHGKAADWWSVGILLFEMLTGRSPFLAS--NRNDMYKSMIQGNLRMPMFLSSDA---QDLLEKLLVPDPNKRLGSTQ-GFEE | ||||||||||||.. ||||. |||. ||| .|||.| .|| .. . ...|. ..| ...| ...||| ||..|||..|..||.|. . | . TLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVND ISSHPFF | |..| IKNHKWF |
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| Kinase | pk3.AA | TyrKc | 498-757 | 22 | 2.2e-14 | 9.76 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 498-757
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)
FELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTM--DHPFIVRLHFAFQNE-------DFLFMCMDYVPGGELFHHLQ
.|.|.|| | ||.||. . | | |.|.. .. . . | ... .|| ||||. . . . |.. | |.|.| | ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR
KAGK-FPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITS-------VVGSKNGGEGGF--ATTFCGTPEYLAPEIIT
| .. .. . . . | ||||.|.| ||. |.|..|....| .|||||. . . .| ...|| .||| |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR-----WMAPECIN
GAGHGKAADWWSVGILLFEMLT-GRSPFLA-----SNRNDMYKSMIQGNLRMPMFL---------SSDAQDLLEKLLVPDPNKRLGSTQGFEEI
. | || |....|..| | .| . .... ||. .... ... .. .. ||..| .. |..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
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| Kinase | pk3.AA | Pkinase_Tyr | 498-644 | 27 | 2.3e-09 | 32.35 | Pfam | 95-253 (270) | Show / Hide |
Range on Protein: 498-644 Range on HMM: 95-253/270 Sequence Identity: 27% (44 aa) FELLKVLGVGSFGRVYLVRRK----DTGKFYAMKVLNKKDMLKK-KQIAHTNTEKMVLSTM-DHPFIVRLHFAFQ-NEDF--LFMCMDYVPGGELFHHLQ ...|.|| |.||.||. . | .|. | |.|. . | . .. . . | ..... .|| ||||. . .. ... | |.|.| | ..|. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR KA---GKFPEELAKFYIAEVICS-LHYLHSNNIIYRDIKPENILLDEEGHIKLTDFGLSK | .. . . .. |.. . ||.|.|.| ||. |.|..|....| .||||.. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |
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| Kinase | pk3.AA | Pkinase_Tyr | 689-705 | 42 | 1.591784 | 2.4 | Pfam | 198-216 (270) | Show / Hide |
Range on Protein: 689-705 Range on HMM: 198-216/270 Sequence Identity: 42% (8 aa) WSVGILLFEMLT-GRSP-F || |.|..|..| |..| . WSFGVLMWEIFTYGEQPTY |
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