Gene DhkH (Slime mold)

DhkH

Species: Slime mold
Alias: DhkH, DdisK270, DDB0219944
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
DhkH.AA Protein None 1378 None Fasta, JSON
DhkH.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of DhkH.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA DhkH.AA HisKA 491-558 31 1.4e-14 55.66 SMART 1-89 (89) Show / Hide 
Range on Protein: 491-558
Range on HMM: 1-89/89
Sequence Identity: 31% (28 aa)

SKALFLQTMSHEMRTPLAGIMGINSWLSTSS--------PQLTSEQLDGC-------------HTIDMCAEALLVLINNILDLSKLEEN
.|  || .||||.||||..|.|  . | ...        . |..||. .              .||. .|. .. |||..||||..|..
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA DhkH.AA HisKA 491-558 38 2.5e-14 52.89 Pfam 1-69 (69) Show / Hide 
Range on Protein: 491-558
Range on HMM: 1-69/69
Sequence Identity: 38% (27 aa)

SKALFLQTMSHEMRTPLAGIMGINSWLSTSSPQLTSEQ--LDGCHTIDMCAEALLVLINNILDLSKLEEN
.|  || .||||.||||..|.|  . | . .. |..||   .  .||. .|. .. |||..||.|..|..
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HATPase_c DhkH.AA HATPase_c 605-804 22 7.1e-35 123.61 Pfam 1-120 (120) Show / Hide 
Range on Protein: 605-804
Range on HMM: 1-120/120
Sequence Identity: 22% (47 aa)

GDFYRIRQVLTNLISNSVKFTPANGQIIVGCEIYHETTPSTRKRSSLDSIEITIPCNHNNSNNSNNNHNHNNNNNNNNHLNCSGSFNNNGFNHGHHHHHH
||  |..||..||..|..|.||..|.| | ..  .                                                                 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----------------------------------------------------------------

HHHHHHHHHDKHCDQKIIVPGKYGKLLFWVIDNGIGIPE------EGREKLFQTFSQYDA-STTRKYGG--SGLGLAISKRLTQLLGGDIWFESQKGKGS
                       . . . |.|||.|||.      | ....|. | ..|. |. |||||  .||||.|..|. ...||.||.||. |.|.
-----------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGT

SFHFLVEVF
 |.| . . 
TFTFTLPLE
HATPase_c DhkH.AA HATPase_c 605-809 19 2.1e-34 121.52 SMART 1-130 (130) Show / Hide 
Range on Protein: 605-809
Range on HMM: 1-130/130
Sequence Identity: 19% (46 aa)

GDFYRIRQVLTNLISNSVKFTPA-------------NGQIIVGCEIYHETTPSTRKRSSLDSIEITIPCNHNNSNNSNNNHNHNNNNNNNNHLNCSGSFN
||  |.||||.||..|..|.||.             .|.| |  .                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

NNGFNHGHHHHHHHHHHHHHHHDKHCDQKIIVPGKYGKLLFWVIDNGIGIPE------EGREKLFQTFSQYDA--------STTRKYGG--SGLGLAISK
                                        . |.|||.|||.      | ....|. | . |         |..|||||  .||||.|.|
---------------------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICK

RLTQLLGGDIWFESQKGKGSSFHFLVEVFFPDYP
|. ...||.||.|            ... .|  .
RIVEQHGGTIWVE----------TTFTFTLPLER
Kinase DhkH.AA HisK 605-804 18 2.1e-29 102.71 In-house 1-164 (164) Show / Hide 
Range on Protein: 605-804
Range on HMM: 1-164/164
Sequence Identity: 18% (45 aa)

GDFYRIRQVLTNLISNSVKFTPANG-----QIIVGCEIYHETTPSTRKRSSLDSIEITIPCNHNNSNNSNNNHNHNNNNNNNNHLNCSGSFNNNGFNHGH
 |  ||.|.| |||||..|||  .|     .| .  |.. ....                                                        
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN-I------------------------------------------------------

HHHHHHHHHHHHHHDKHCDQKIIVPGKYGK---------------------LLFWVIDNGIGIPEEGREKLFQTFSQ----------YDASTTR--KYGG
                          ||                       . . |.| |.|.|||  .|.|. |..          ..       .  |
--------------------------KY-NSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHG

SGLGLAISKRLTQLLG--------GDIWFESQKGKGSSFHFLVEVF
 ||||.|...| ..||        . | ..|..||||.| |... .
CGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
REC DhkH.AA REC 1243-1360 22 4.7e-29 103.75 SMART 1-150 (150) Show / Hide 
Range on Protein: 1243-1360
Range on HMM: 1-150/150
Sequence Identity: 22% (36 aa)

LKIMVAEDS----LVNQKVAC------RFLTKLGYK-----KEEIIFVVNGQ-------QAIDHIENVE------------MVDVILMDMQMP-------
..|....|.     |....        |.|.|.||      .|... . .|.       .|.. ... .             .|.|.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

EVDGCEATTRIRMRYPTTGPHIIGLTANAFNEDKDKCLLSGMCHYLAKPVKMDILAVEL
..|| |.. |||         || |||..  ||. ..| .|.  |. ||.... |   .
GMDGIELCRRIR--------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg DhkH.AA Response_reg 1245-1361 27 9.8e-18 66.1 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1245-1361
Range on HMM: 1-115/115
Sequence Identity: 27% (33 aa)

IMVAEDSLVNQKVACRFLT-KLGYKKEEIIFVVNGQQAIDHIENVEMVDVILMDMQMPEVDGCEATTRI-RMRY-PTTGPHIIGLTANAFNEDKDKCLLS
.....|. .....  ..|. | ||  |..  . .|..|.. ...   .|.|.||..||..|| |...|| | .. |.  . || .||..  .|. ..|  
VLIVDDHPLMREGLRQILEQKEGY--EVVAEADDGEEALEWWQEHH-PDLIIMDINMPGMDGLELCRRIRRQHPHPQ--TPIIMCTAHGDEDDAVEALQA

GMCHYLAKPVKMDILAVELK
|.  |..||...| |  ...
GANDYITKPFDPDELHAAIR