Rio1

Species: Slime mold
Alias: DdisK282, Rio1, DDB0216428
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
Rio1.AA Protein None 574 None Fasta, JSON
Rio1.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of Rio1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Rio1.AA RIO1 163-384 60 3e-150 505.46 In-house 1-225 (225) Show / Hide
Range on Protein: 163-384
Range on HMM: 1-225/225
Sequence Identity: 60% (136 aa)

QVLDPRTRLMLFKMINKGAFSEINGCISTGKEANVYHAFTPNEE--ERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVKVWAEKEFRNLTRL
||.|||||..||||. .|   |||||||||||.||||| . | .  |.|.|.|||||||||||..|| ||||||.|..|||||||.|.|||||.||| |.
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI

KNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVSQEKFG-VIYLDCIKMMRTLFHKCRLVHADLSEYNMLYYKNQLYIIDVSQSVEHDHPHSLDF
  . |||| |.......|.| |||||| |||||||.  .  .    .|.  |. ||..   |||||||||||||||.   ||.|||||||||||||||.|
YQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSLEF

LRMDCSNVTDFFRKKEVNTMFIQEL
||||| || ..|.|. | .. . ..
LRMDCKNVNMYFMKHNVIIFPVRDI

RIO Rio1.AA RIO 154-390 53 3.4e-132 446.4 SMART 1-253 (253) Show / Hide
Range on Protein: 154-390
Range on HMM: 1-253/253
Sequence Identity: 53% (135 aa)

DKEDRATTEQVLDPRTRLMLFKMINKGAFSEIN--GCISTGKEANVYHAFT----PNEEERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVK
||||.|| |.|.|||||. |.||.|.| ..|||  ||||||||||||||..    .| .|.|||.|.||...||...||..|.|||. ||...|.||||.
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

VWAEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVSQEKFGV---IYLDCIKMMRTLFHKCRLVHADLSEYNMLYY------KN
.||||||||| |...||.|||.|  .|.|.||| |||.||..||||||..  ...  .   .| . .  || ..| |.|||||||||||||       ..
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

QLYIIDVSQSVEHDHPHSLDFLRMDCSNVTDFFRKKEVNTMFI-QELFEFITD
 ..|||.|||||.|||..|.||..|. |...|||.| | .  |  |.||.||.
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG

Kinase Rio1.AA RIO 161-398 36 1.6e-130 439.91 In-house 1-276 (276) Show / Hide
Range on Protein: 161-398
Range on HMM: 1-276/276
Sequence Identity: 36% (100 aa)

TEQVLDPRTRLMLFKMINKGAFSEINGCISTGKEANVYHAFTPNEE-----------ERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVKVW
 ||..||.||....||.|.|   ....||..|||...||. . | |           |.| |...|....||||..|. |||.|. ...|||.|.|.. |
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVS-QEKFGVIYLDCIKMMRTLFHKCRLVHADLSEYNMLYYKNQL-------Y
||||.||. ||  .|.|||.|.....|.||| ||..|. .||.....  .  |    .|..|.  ||.| . |||||.|..|.||... . .       |
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

IIDVSQSVEHDHPHSLDFLRMDCSNVTDFFRKKEV-NTMFIQELFEFI------------------TDLTITEDNI
.||..|.|||||||.|...|.|| .| .|| |. |  ..   |.|.|                   ...|....|.
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM

Kinase Rio1.AA RIO1 196-384 49 3.6e-115 359.65 Pfam 1-200 (200) Show / Hide
Range on Protein: 196-384
Range on HMM: 1-200/200
Sequence Identity: 49% (99 aa)

NVYHAFT-PNEE-ERAVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMVKVWAEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIG-KDGYAAPR
||||| . .... |.|||.|.|....||...||. ..|||| .|..||.|.||..||||||||| |...||.||| |  ...|.||| ||| |||..|||
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

LKDAT----VSQEKFGVIYLDCIK-MMRTLFHKCRLVHADLSEYNMLYYKN-QLYIIDVSQSVEHDHPHSLDFLRMDCSNVTDFFRKKEVN--TMFIQEL
|||.      |.|..  || ..|   || . ..|.|||.||||||.|....  ..|||..|.|||||||.|.||..|| |. .|||.| |.  .| . |.
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDERVMDFREI





Kinase Rio1.AA RIO3 158-399 47 2.5e-85 287.71 In-house 1-254 (254) Show / Hide
Range on Protein: 158-399
Range on HMM: 1-254/254
Sequence Identity: 47% (121 aa)

RATTEQVLDPRTRLMLFKMINKGAFSEINGCISTGKEANVYHAF-TPNEEER----------AVKVYKTSILVFKDRDRYVTGEFRFRRGYSKHNPRKMV
 .|.|. .||.|||...||.| | .  | |||.||||. |.||.    |.|.          |.||.||..  ||.||.|.  .|||.  .|| ||||. 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

KVWAEKEFRNLTRLKNAGIPCPTPLILRNHILVMTFIGKDGYAAPRLKDATVSQEKFGVIYLDCIKMMRTLFHKCRLVHADLSEYNMLYYKNQLYIIDVS
..|||||  ||.|.. ||||||| ..|. |||||.|||.|   ||.||.  .  |.    | . ...|| |.|.| ||||||||||||..  ....||||
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVS

QSVEHDHPHSLDFLRMDCSNVTDFFRKKEV-NTMFIQELFEFITDLTITEDNID
||||  ||| |.||  || ||..||.|  | ...  .|||. .. | || ||  
QSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEA