Gene DDB0219986 (Slime mold)

DDB0219986

Species: Slime mold
Alias: DdisK032, DDB0219986
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0219986.AA Protein None 1887 None Fasta, JSON
DDB0219986.kin_dom Protein Kinase Domain None 237 None Fasta, JSON

Protein domain

Protein domains of DDB0219986.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RCC1 DDB0219986.AA RCC1 206-258 37 3.2e-13 45.8 Pfam 1-52 (52) Show / Hide 
Range on Protein: 206-258
Range on HMM: 1-52/52
Sequence Identity: 37% (21 aa)

QGNLYTFGDGLLGKLG--HGNLESYSSPKL-VEFFQTKPSLRVVSIANGGKHSLAL
.| .||.| .  | ||  ||.  . . |.. |||.      |||..| |. |..||
DGRVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-G--NVRVVQVACGWQHTMAL
RCC1 DDB0219986.AA RCC1 261-353 17 1.1e-08 31.06 Pfam 1-52 (52) Show / Hide 
Range on Protein: 261-353
Range on HMM: 1-52/52
Sequence Identity: 17% (16 aa)

CGKVYSWGGNDSCQLGLGNGSSSSYYSLPQL-INFNISYNNNNNNNNNNSTNNNNNNNNDGAQQQFSLSQNSSSNNNKIKIVKLSCGTNRSAVI
 |.||.|| ||  |||.  . .. . . ||. ..|  .                                       ....|. .|| . ....
DGRVYTWGCNDYGQLGR-IHGDT-NCHVPQQIVEFL-G---------------------------------------NVRVVQVACGWQHTMAL
RCC1 DDB0219986.AA RCC1 356-407 25 2.2e-16 56.04 Pfam 1-52 (52) Show / Hide 
Range on Protein: 356-407
Range on HMM: 1-52/52
Sequence Identity: 25% (14 aa)

KGLLFTFGRGDHGRLGLGEQSLLMQSTPKL-VQSLQG-HFIIDMSSGGGHSLVL
.| ..|.|..|.|.||. ...   ...|.. |..| |   ......|. |...|
DGRVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-GNVRVVQVACGWQHTMAL
RCC1 DDB0219986.AA RCC1 410-468 26 3.4e-18 61.96 Pfam 1-52 (52) Show / Hide 
Range on Protein: 410-468
Range on HMM: 1-52/52
Sequence Identity: 26% (16 aa)

KGLVFSFGRNDQGQLG-IGCFSNQQTIPKQ-IQWFQTSQQQQQQPINIIKVSAGGYHSIAI
.| |...|.||.|||| |.. .  ...|.| .. .         .. ...|..|..|..|.
DGRVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-G-------NVRVVQVACGWQHTMAL
RCC1 DDB0219986.AA RCC1 471-526 28 5.5e-10 35.3 Pfam 1-52 (52) Show / Hide 
Range on Protein: 471-526
Range on HMM: 1-52/52
Sequence Identity: 28% (16 aa)

NNDTYAWGRSDYGVLGTSIDVQGDRNLPVL-INSNSVVVDNVKFIDVSSGFQHNVAM
. . |.||. ||| ||   .   ... |.. ...      ||....|..| || .| 
DGRVYTWGCNDYGQLGRIHGDT-NCHVPQQIVEFL-G---NVRVVQVACGWQHTMAL
RCC1 DDB0219986.AA RCC1 529-579 25 7.7e-07 25.09 Pfam 1-52 (52) Show / Hide 
Range on Protein: 529-579
Range on HMM: 1-52/52
Sequence Identity: 25% (14 aa)

DGSLYSWGCNAGQRLG--FKSDENQLTPKKCFINSKDS--KPLLFTCGEIITIIV
||..|.||||   .||   ..  |...|..  ...  .  .     ||   |...
DGRVYTWGCNDYGQLGRIHGDT-NCHVPQQI-VEFL-GNVRVVQVACGWQHTMAL
Kinase DDB0219986.AA CAMKL-Unclassified 1201-1437 56 2.9e-183 615.13 In-house 29-290 (290) Show / Hide 
Range on Protein: 1201-1437
Range on HMM: 29-290/290
Sequence Identity: 56% (149 aa)

VSLLKQMNHKCIMPIQAVFYDRNA-----------------------FMQMEYISGGNLLDWCRNNNNDNENNKRRQPWEIQKIFQQIIQAIAYMHSNCI
....|.|||.|.|.|..||.....                       .|.|||..||.||||||.|...||||.||||||||..||||..|..|.|.|||
IKFVKTMNHGCAMDIDMVFREAEILKSLNHKNIVKIKNCYTLSDMKVVMIMEYLQGGELLDWCRKNGHFNENNARRQPWEIQQYFQQIVDAMQYCHKNCI

IHRDLKLENVLIR-QDGTPVISDFDLSKDISANVNVTVFNINGGTELYKAPEMKEQNVKG-SYSTDIWAFGVMLYKCIFQFVNNNNNGNNGKNNNSDGNE
|||||||||||.| ||..|||..||......||||..|||||||...|.|||||.|.||. .||.||||.|||||.||.||...|.||||||||||||||
IHRDLKLENVLLRQQDSSPVIKIFDFGIAGVANVNQNVFNINGGSLRYMAPEMKNQQVKQIQYSIDIWAMGVMLYMCIVQFFPFNGNGNNGKNNNSDGNE

NDNNNNNNFLIIREPFLLPEENNLPLPANHSDQRLISLLSSIFQRNPKLRPTAHQIAVHPYF
||||||..|.|.|.|...||..|.|||....|||||||...|||.|||.|.|.|||..||..
NDNNNNIMFKITRGPYEFPEQINKPLPDECKDQRLISLIENIFQVNPKNRFTTHQIMQHPWM
Kinase DDB0219986.AA CAMKL 1201-1437 25 2.5e-68 217.13 In-house 63-297 (297) Show / Hide 
Range on Protein: 1201-1437
Range on HMM: 63-297/297
Sequence Identity: 25% (64 aa)

VSLLKQMN---HKCIMPIQAVFYDRN-------AFMQMEYISGGN--LLDWCRNNNNDNENNKRRQPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVL
....|..|   |. |. .  |.....        .. |||.|||.  |.|. ... . .   .| ...| ...|.||. |..|.||..|.|||.|.||.|
IQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRR---GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL

IRQDG--TPVISDFDLSKDISA--NVNVTVFNINGGTELYKAPEMKEQ--NVKGSYSTDIWAFGVMLYKCIFQFVNNNNNGNNGKNNNSDGNENDNNNNN
. ..|  .  |.|| .|  .    . .   ...  |.  | |||. .        . .|||. ||.||  ..  .  ..  .| |             ..
LDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-K-------------QG

NFLIIREPFLLPEENNLPLPANHSDQRLISLLSSIFQRNPKLRPTAHQIAVHPYF
.. | ..     .    | . .| . ....|.... |.||. |||.|||  || .
KDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase DDB0219986.AA CAMK 1190-1350 19 1.1e-41 131.65 In-house 71-325 (425) Show / Hide 
Range on Protein: 1190-1350
Range on HMM: 71-325/425
Sequence Identity: 19% (49 aa)

DAFGKQIFERQVSLLKQ-------MNHKCIMPIQAVFY--------------------DRNAFMQM---EYISGGNLLDWCRNNNNDNENN---------
... .. ..| ....|.       ..|..|  .  |.                     |.. .| |   ||.||| |.| . .   .....         
RPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDI

---KRRQPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQD-----------------GTPVISDFDLSKDISANVNVT-----------------
   .| . .| ...|.||..|..|.||. |.|||||.||.|. ..                 ..  |.|| ... .  . | .                 
VERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTP

----VFNINGGTELYKA-PEMKEQ-------------NVKGSYSTDIWAFGVMLY
     ..   ||  | | ||. ..             .   ....|.|. ||.||
TEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase DDB0219986.AA Ciliate-E2-Unclassified 1194-1437 22 4e-41 140.4 In-house 54-352 (352) Show / Hide 
Range on Protein: 1194-1437
Range on HMM: 54-352/352
Sequence Identity: 22% (68 aa)

KQIFERQ---VS--------LLKQMNHKCIMPIQAVF-YDRNAFMQMEYISGGNLLDWCRNNNN----------DNENNKRRQPWEIQ-----KIFQQII
|......   ..        .|....| .|.    .|  . | .. |||. ||.|.........          .....|. .  ...     ..| ||.
KEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQIL

QAIAYMHSNC-IIHRDLKLENVLIRQDG---TPVISDFDLSKDISANVNVTVFN------IN--------GGTELYK----APEMKEQNVKGS---YSTD
|.. |.|..  |||||.|.||.|. ..|    . |.|| .|| .  |.| . .|      |.         ||  |.    |||. ...  .    |. |
QGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCD

IWAFGVMLYKCIFQFVNNNNNGNNGKNNNSDGNENDNN-----NNNNFLIIREPFLLPEEN-----NLPLPANHSDQRLISLLSSIFQRNPKLRPTAHQI
||..|| || ..|.      ..|| . .. . ...  |     .  .  . ....  ....     ...  | .  .    ||..... ||. |.|. ||
IWSLGVILYEMLFGY--YPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN---DLLQKMLKKNPNKRITFEQI

AVHPYF
  ||.|
LNHPWF
Kinase DDB0219986.AA Pkinase 1201-1437 23 9.8e-41 145.12 Pfam 51-293 (293) Show / Hide 
Range on Protein: 1201-1437
Range on HMM: 51-293/293
Sequence Identity: 23% (63 aa)

VSLLKQMNHKCIMPIQAVFY-DRNAFMQMEYISGG----NLLDWCRNNNNDNENNKRR--QPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQDG
....| .||..|  .  .|. ...  | |||  ||     | |. .      .....   ..||..... ||.....|.||. |||||||.||.|| ..|
IQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNG

TP----VISDFDLSKDISANVNVTVFNINGGTELYKAPEMKEQNVKGSYSTDIWAFGVMLYKCIFQFVNNNNNGNNGKNNNSDGN----ENDNNNNNNFL
..     |.|| |.| .. . | . ..   ||  | |||    . . ... |.|..|..||  ..            ..   .|     . .. .   ..
HIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC------------GRPPFPGHCWHDN-HDQMQMICR

IIREPFLLPEENNLPLPANHSDQR-------------LISLLSSIFQRNPKLRPTAHQIAVHPYF
| . |.  ....  . .  . ...             ............|| ||||.||  ||.|
IMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0219986.AA Ciliate-E2 1025-1437 16 8.5e-35 116.87 In-house 42-365 (365) Show / Hide 
Range on Protein: 1025-1437
Range on HMM: 42-365/365
Sequence Identity: 16% (81 aa)

QNLCDDDDNNHENNSVNNNSNNNNNNNNNNNNNNNNNNNNNNNIDNNINSNSINDSSNNNNNNNNIEKLKNELIKLKKDEQKLLSNQQEINELI--IEIL
|                                                                 || |. .. .|  ... . ..  .. ..  |.. 
Q-----------------------------------------------------------------EKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-

DKYVPEFKIKLRANDKISSRIKDTGLLVTDRKFQHYDIIKTLSTHPHNVYLANFNDQLVVLKEFGIGDAFGKQIFERQVSLLKQMNHKCIMPIQAVFY--
.                                                                    . |.| |..  .|.|.||. |. .  .|.  
F--------------------------------------------------------------------Y-KKINEKN--ILEQLNHPNIIKMYECFQEK

-DRNAFMQMEYISGGNLLDWCRNN-NNDNEN-------NKRRQPWEIQKIFQQIIQ---------------AIAYMHSNC-IIHRDLKLENVLIRQDGTP
 | | .. |||..||.|.|...||  . |..       . .    ||..|..||.|               |. |.||.  |||||.|.||.|.     .
DDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEK----EIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

VISDFDLSKDISAN-------VNVTVFNING-----------------------GTELYKAPEMKE-QNVK-------GSYSTDIWAFGVMLYKCIFQ--
 |.|| |||... .       .    .   .                       ||  |.|||. . ..          .|. |||..||.|| ..|   
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

-FVNNNNNGNNGKNNNSDGNENDNNNNNNFLIIRE-PFLLPEE--------NNLPL---PANHSDQRLISLLSS----IFQRNPKLRPT-AHQIAVHPYF
 |                           . .| . .. .|..        . . .     .. .|  . |..     ..|..|. |.| . ||  ||.|
PF---------------------------QQQIKQCKIDFPCPEWQKDTQCI-Q-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DDB0219986.AA S_TKc 1158-1437 21 5.2e-34 120.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 1158-1437
Range on HMM: 1-231/231
Sequence Identity: 21% (65 aa)

YDIIKTLST-HPHNVYLANFND--QLVVLKEFGIGDAFGKQIFERQVSLLKQMNHKCIMPIQAVFYDRNAFMQMEYISG--GNLLDWCRNNNNDNENNKR
|.|....       ||..  ..  ..| .|.         . ..| ...||. .|. |  .  ||.| . .| |||..|  |.|.|  ....    ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG-LRFP

RQPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQDGTPVISDFDLSKDISANVNVTVFNINGGTELYKAPEMKEQNVKGSYST---DIWAFGVML
  . .......||..|..|.||. ||||||| ||.|. .  .  |.|| |.. .         .   ||  | |||.       .|..   |.|..|..|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCIL

YKCIF-QFVNNNNNGNNGKNNNSDGNENDNNNNNNFLIIREPFLLPEENNLPLPANHSDQRLISLLSSIFQRNPKLRPTAHQIAV-------HPYF
| ..  .                       . .  | .|.                  .. ...... ..|..|. |||| ..         ||.|
YEMLCGYPPFP-------------------QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0219986.AA CAMK-Unique 1197-1350 22 5.3e-33 106.14 In-house 63-284 (363) Show / Hide 
Range on Protein: 1197-1350
Range on HMM: 63-284/363
Sequence Identity: 22% (50 aa)

FERQVSLLKQMNHKCIMPIQAV----FYDRN----------------AFMQMEYISGGNLLDWCRN--------------------NNNDNENNKRRQPW
..| ....|  .| .| ..  .    | ||.                 .. |||. || |.||.                      .  ..|       |
LKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSE-----RCW

EIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQDGTP----------------VISDFDLSKDISANVNVTVFNINGGTELYKAP-------------
... |.|.. .|.|||||. |.||||||||....  .                  ...||.|..... |   ..  .  ||..|.||             
DTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTR

-EMKEQNVKGSYST---DIWAFGVMLY
 |. ..   .. .    |||. ||..|
DEVINMQCYDQQCSPASDIWSLGVIMY
Kinase DDB0219986.AA TKL 1171-1431 15 1.4e-30 107.32 In-house 9-360 (364) Show / Hide 
Range on Protein: 1171-1431
Range on HMM: 9-360/364
Sequence Identity: 15% (59 aa)

VYLANFND----------QLVVLKEFGI--GDAFGK-------------------------QIFERQVSLLKQMNHKCIMPIQAVFYDRN----------
|| ....           . |. | | .   | | |                         . .|... .... .|  | .. ..  . .          
VYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVG

----AFMQMEYISGGNLLDWCRNNNNDNENNKRRQPWEI-QKIFQQIIQAIAYMHS--------NCIIHRDLKLENVLIRQDGT--------------PV
     .. |||..||.||.                 |.   .. ..| ....|.||          ||||||| .|.|. ...|              . 
PWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ISDFDLSKDISAN-----------------VNVTVFNINGGTELYKAPEMKEQN---------------VKGSYSTDIWAFGVMLYKCIF--QFVNNNNN
|.|| ||...| .                 .| .  .  .||  . |||. ...                . | ..|...||..|. ..   .       
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-------

GNNGKNNNSDGNENDNNNN----------NNFLIIREPFLLPEENNLPL------PANHSDQRLISLLSSIFQRNPKLRPTAHQI
              .....            | .. . .| |.  . ..      | .. ......|.    . .|. ||.. .|
------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI
Kinase DDB0219986.AA Ciliate-E2a 1193-1350 29 3.3e-26 74.18 In-house 42-207 (275) Show / Hide 
Range on Protein: 1193-1350
Range on HMM: 42-207/275
Sequence Identity: 29% (52 aa)

GKQIFERQVSLLKQMNHKCIMPIQAVFYDRNA-FMQMEYISGGNLL-----DWCRNNNNDNENNKRRQPWEIQKIFQQII-QAIAYMHSNCIIHRDLKLE
||. |.. .....|..|. |. .  |. | |  .. |||..|| |.     ... . .            || .| ||.. |...|||...|.|||||.|
GKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE----------IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPE

NVLIR---QDG----TPVISDFDLSKDISANVNVTVFNINGGTELYKAPE---MKE--QNVKGSYSTDIWAFGVMLY
|.|..   ...      .|.|| |...|. . .  .| .  ||  | |||   .||  .. . ... |.|  ||..|
NILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKC-GTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFY
Kinase DDB0219986.AA Dicty3 1203-1346 23 3.1e-25 80.11 In-house 52-284 (351) Show / Hide 
Range on Protein: 1203-1346
Range on HMM: 52-284/351
Sequence Identity: 23% (56 aa)

LLKQMNHKCIMPIQA--VFYDRN---AFMQMEYISGGNLLDWCRNNNND--NENNKRRQPWEIQKIFQQIIQAIAYMHSNC-IIHRDLKLENVLIRQDGT
..| |.|.||.   .    .|.|   ..  ||||.|....     | |.  . .|.|  . || ||  ... ...| | || |||||.| .|... .| .
INKKMRHPCIVKYYGACYCCDNNNDNHYIYMEYIEGEIPISFVKTN-NMLKKHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQ

--------PVIS------------------DFDLSKDISANV---------------------------------------NVTVFNIN-----------
           |                  ||.|||.|| ..                                       |  | .||           
HQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNNIYSNKQYKQ

-----GGTELYKAPEMKEQNVKG-SYSTDIWAFG
     .||. | ||| | .| .. ... ||| .|
KCYSICGTIHYMAPEIKLNNQCCACRKSDIWSLG
Kinase DDB0219986.AA STE 1194-1349 21 9.5e-23 77.23 In-house 72-258 (359) Show / Hide 
Range on Protein: 1194-1349
Range on HMM: 72-258/359
Sequence Identity: 21% (42 aa)

KQIFERQVSLLKQMN--HKCIMPIQAVFYDR--------NAFMQMEYISGGNLLDWCRNNNNDNENNKRRQ-------PWEIQKIFQQIIQA-IAYMHSN
.| ... ....|..|  |. |      ...         . .. |||..|| | |  ...   .....  .         .| .| .||...  .| ||.
MQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSH

CIIHRDLKLENVLIRQDGTPVISDFDLSKDISANVN--------------VTVFNINGGTELYKAPEMKEQNVKG-----SYSTDIWAFGVML
 |||||.|  |.|.       ..|| ... .. ..               .   |   ||  . |||. .|| .|     ... ||| .| ..
HIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase DDB0219986.AA TyrKc 1180-1437 20 2.5e-11 -39.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 1180-1437
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

LVVLKEFGIG---------------------DAFGKQIFERQVSLLKQM--NHKCIMPIQAVFYD--------RNAFMQMEYISGGNLLDWCRNNNNDNE
.. .|. | |                     ||  .. | |  .....   .|..|  . .|  .           .. ||| ..|.|.|  |.. ..  
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

NNKRRQPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQDGTPVISDFDLSKDISAN----VNVTVFNING--GTE--L---YKAPEMKEQNVKG-
     .. .  ..  || .  .| ||...|||||   |.|.  ..|  |||| ||.||       ..  .    .  |.   |     |||      .| 
----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYGK

-SYSTDIWAFGVMLYKCIFQFVNNNNNGNNGKNNNSDGNENDNNN-----NNNFLIIREPFLLPEENNLPLPAN-------HSDQRLISLLSSIFQRNPK
 .  .|.|.|||...  ||                ..| .    .      .|. .|.   .. . . .| |.|       .  . . .. ..  ...|.
FTTKSDVWSFGVCMW-EIF----------------TYG-QQPYPGMIQQMMSNQEVIE---YVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

LRPTAHQIAVHPYF
 |||  .|  | .|
DRPTFSEI--HECF
Kinase DDB0219986.AA CAMK 1406-1437 25 6.6e-09 24.08 In-house 387-425 (425) Show / Hide 
Range on Protein: 1406-1437
Range on HMM: 387-425/425
Sequence Identity: 25% (10 aa)

SDQ-------RLISLLSSIFQRNPKLRPTAHQIAVHPYF
||.         ..|.... |..|. |.|..|.  || .
SDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DDB0219986.AA Ciliate-E2a 1413-1437 40 0.000249 8.68 In-house 251-275 (275) Show / Hide 
Range on Protein: 1413-1437
Range on HMM: 251-275/275
Sequence Identity: 40% (10 aa)

LLSSIFQRNPKLRPTAHQIAVHPYF
|..   . .|| |.|| |.  ||.|
LMKKMLEKDPKKRITAQQALNHPWF
Kinase DDB0219986.AA STE 1410-1437 30 0.00026 11.27 In-house 330-359 (359) Show / Hide 
Range on Protein: 1410-1437
Range on HMM: 330-359/359
Sequence Identity: 30% (9 aa)

LISLLSSIFQRNPKLRPTAHQIAV--HPYF
..  ..  .|..|. ||||.|     || .
FKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0219986.AA Pkinase_Tyr 1201-1306 27 0.000435 14.47 Pfam 54-161 (270) Show / Hide 
Range on Protein: 1201-1306
Range on HMM: 54-161/270
Sequence Identity: 27% (31 aa)

VSLLKQM-NHKCIMPIQAVFY--DRN--AFMQMEYISGGNLLDWCRNNNNDNENNKRRQPWEIQKIFQQIIQAIAYMHSNCIIHRDLKLENVLIRQDGTP
....||. .|. |    .| .  ..    .. |||  .|.|||  |..    |....  . .. .. .|| .. .| .|. .|||||   |.|.  ... 
AKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVV

VISDFDLSKDI
 |.|| |..||
KICDFGLARDI
HECT DDB0219986.AA HECT 1577-1887 29 1.5e-81 280.46 Pfam 1-329 (329) Show / Hide 
Range on Protein: 1577-1887
Range on HMM: 1-329/329
Sequence Identity: 29% (102 aa)

LLNSNDLFNNNNNNN-EENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEENPLLILKNEFTIFKILGKIFLKSIIDGKPIPDCFPTSFFKYLL--GV
.| ....||.|..   |. ..|..   .|...|.  .. |   |             .   |...|| ||.|. |.|..| |..  || .|.||||  | 
TLMCKEIFNPNYGMFREYQTPNSGYYWPNPPMNRDCYIPNSSIN-------------PDHLEYRWFKFLGRIIGKCIYNGIPLDIPFPPFFWKYLLGNGK

KVNLRDLEIYDPQLAQSFKKVLVLDN---------I--EEYLSTTFEG--------------L-I-EGGESIPVTDLNKEEFIQRNIERVLVGCRQSKLE
...|.||| .||.|..|.|. | ..|         .  . . ......              | | ..|..||||. ||||.|.. .. .|. . .  .|
PITLEDLEEIDPELYNSLKWLLEMENDGDDESIEDLRFCLTFTVPWDDGYFGETKTVEEHLILEIFPNGRNIPVTNENKEEYINLYCDYRLNKQIKKQFE

AFKSGFMSIDSLNAHFALFSPTELQLLMCGNTL--VDSSVLQKNFKFI--GFPDTSSTPKDFRRAVDEMNQDEIRLFLRFVTGMVALPLSGFEK----SI
||..||...  ...   .|.| ||.||.||.    .| . ..|....   |.  .| | . | ..|.|..|.. |.||.||||.  ||..||..    ..
AFRKGFYEVIPPEWLS-MFTPEELELLICGSPEQWIDWEDWKKHTEYDDHGYTKNSPTIQWFWEIVEEFTQEQRRKFLQFVTGCPRLPVGGFKWNLQPKF

SIIQVPLSQKLPCAHTCSYQLDLPDYNDFDTTKKKLIKMLEYV-DG-FAFI
.|        || ||||. .|.||.| . .. ..|| . .|.  .| | |.
TI--------LPTAHTCFNYLKLPPYSSKEIMREKLLYAIEHCQEGQFGFS
HECTc DDB0219986.AA HECTc 1500-1887 18 2.1e-29 104.92 SMART 1-407 (407) Show / Hide 
Range on Protein: 1500-1887
Range on HMM: 1-407/407
Sequence Identity: 18% (90 aa)

IESNKLFCR-----LEVSF------QGEKGLDLGGLSSEMYSLLFSDNQIIDNSNNSNNSVSYSIPKNSLFSKKFNLFENSGTESPFYLLNSNDLFNNNN
..... . .     ||. |      .|| |.| ||.. | ..||    .                                                   
NHNMDDLKKRRQMMLEIEFVVNWHFDGEEGIDYGGPTREWFFLLCKEMFNP-------------------------------------------------

NNNEENNNNNNNNNNNNNNNNNNNNNNNNNNNN------------------NNNNNEENPLLILKNEFTIFKILGKIFLKSIIDGKPIPDCFPTSFFKYL
                     ...    ..|.|                  |. ....|.. . .     |. .|..  | |.... ..  |. .|.|.|
--------------------DMYGMFRYSPNDNHNMVKPDYIQYNRYWLWPNPHCCFCNHEHLNQV---WFRFIGRVMGKCIYHNCLVDCHFTRHFYKKL

LGVK----VNLRDLEIYDPQLAQSFKKVL-----------------VLDNIEEY--LS--TTF----EG---------LIEGGESIPVTDLNKEEFIQRN
||..    |.. |.| .|| . ||... .                 .|.. ...  .   .||    .          |...|..||||  ||.|.. . 
LGKPNGTDVTWHDMESFDPEYYQSLVWLIIVQQKRNYEQDQHEQSKSLEYDITDVEMDMCLTFTIVDMKDFGQCKMVELKPNGSNIPVTNENKHEYVHLY

IERVLVGCRQSKLEAFKSGFMSIDSLNAHFALFSPTELQLLMCGNT-LVDSSVLQKNFKFI-GFPDTSSTP---KDFRRAVDEMNQDEIRLFLRFVTGMV
....|..  .  .|||..||  . ..|  ...| . ||.|..||.   .| ......  .  |. ....|    ..| ..|..... | |.||.|.||  
CQWRLNKRIEKQMEAFREGFYEVIPENWMRYMFDEEELELMICGMPDEWDMDDWKEHTEYRGGYTHNHQTIRFKQWFWEVVESFTNEERRRFLQFWTGCS

ALP--LSGFEK--------SISIIQVP-----LSQKLPCAHTCSYQLDLPDYNDFDTTKKKLIKMLEY----VDGFAFI
.||  . || .        ...| ...      .. || ||||  .|.||.|.  .. . ||    ..     .|| | 
RLPASVGGFKALCPSNGPQKFCIHKWGSETCNDDDRLPTAHTCFNRLCLPPYSSKEILREKLLYAINECRICCEGFGFS