FHAK1

Species: Slime mold
Alias: DdisK038, DDB0216370, FHAK1
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: RAD53

Sequence

Name Sequence Type Origin Length Description Download
FHAK1.AA Protein None 593 None Fasta, JSON
FHAK1.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of FHAK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA FHAK1.AA FHA 54-128 34 4.7e-20 77.75 Pfam 1-73 (73) Show / Hide
Range on Protein: 54-128
Range on HMM: 1-73/73
Sequence Identity: 34% (28 aa)

ITIGRSKTCNIVVP-ELI-VSGKHCII-TRADAIENGNTNYGLLMIQD--QSTNGTFI--NGKLIGKGKSRLLKNGDKLCLG
.||||.. |.||..     ||..||.| .. .           . |.|  .||||||.  ||. |..|... |..|| . .|
WTIGRDPDCDIVLDNDPSFVSRHHCEIRRYDNG---------RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG

FHA FHAK1.AA FHA 53-111 30 4.3e-13 50.74 SMART 1-49 (49) Show / Hide
Range on Protein: 53-111
Range on HMM: 1-49/49
Sequence Identity: 30% (19 aa)

NITIGRSKTCNIVVPELIVSGKHCIITRADAIENGNTNYGLLMIQDQS---TNGTFINGKLI
 .||||.. |.|..|.  .| .||.|.     ...        |.| .   ||||..||. .
TWTIGRHS-CDIQLPHPSISRHHCQIR-----DGD-------YIIDLGEHSTNGTYVNGRRV

Kinase FHAK1.AA RAD53 180-472 45 3.2e-213 642.19 In-house 1-305 (305) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-305/305
Sequence Identity: 45% (143 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRVAIKHLNLSKIN---THTPKFKSQLNREIEILKFINHENVVEIYDIFYTKDQQLFFILELANGGELYNKIGFNE
|...||||||||..|.....|.|...||||.....|..   .||.|...|...|.||||..||.....|||||.|........|||..||||.|||..|.
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

PL---LNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDY--------------LKIKITDFGLARFIHEGELAKTLCGSPLYVAPEVILS
..   ..|...|..|.|...||.|||..||.||||||||||........              ..||||||||..|..||...||.||.|.|||||||.|
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

LHHKNKYGTNSSSSSQSPTKDINSVGYGKSCDAWSLGAILYIVLCGTPPFDDDDDEEMSTPQLFEKIVS-GNYRVEKLEKSLISSSAADLVKGLLTVDPD
 .| |.|..|.....|        |||.|..|.||.|.||||.|||.|||.||...||...||||.|.. |.|........ ||..|.||.|..|.|||.
KGH-NCYHENEERQVQ--------VGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPE

KRLTVEQALNHPWI
||.|...||||||.
KRYTIDEALNHPWM

Kinase FHAK1.AA CAMK 185-472 28 2.2e-126 409.5 In-house 1-425 (425) Show / Hide
Range on Protein: 185-472
Range on HMM: 1-425/425
Sequence Identity: 28% (126 aa)

ELGSGNFSVVYEGVNKNTG------------KRVAIKHLNLSKINTH-----------------------TPKFKSQLNREIEILKF-------INHENV
.||.|.|..|.....|||.            ..|||| .. .|.  .                       .|| . .. |||||.|        ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEIYD-------------------IFYTKDQQLFFIL---ELANGGEL----YNKIGFNEPL--------------LNENQSKFIFKQILNAVSYLHSKG
. .|.                   .| |||.......   |.. ||||    ...|  ...               ..| . ...|.||. || |.||..
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDLKPENILFDSYGDDY-------------LKIKITDFGLARFIHE------------------------GELAKTLCGSPLYVA-PEVILSLHHKN
|.||||||||||.|. .||               .|||.|||.|... .                        |.. || ||.| |.| |||... .|.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

KYGTNSSSSSQSPTKDINSVGYGKSCDAWSLGAILYIVLCGTPPFDDDDDEE--------MSTPQLFEKIVSGNYRVEKLEKSL------------ISSS
..  | . .      | .  .||..|| ||.| |||| |||.|||..|.|.|        |. ..||||| .|.|. .  . |             || .
MQ--N-A-T------DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE

--------AADLVKGLLTVDPDKRLTVEQALNHPWI
        . ||....|.|||.||.|.||.|||||.
FHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase FHAK1.AA S_TKc 180-472 34 1.4e-105 358.02 SMART 1-231 (231) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-231/231
Sequence Identity: 34% (105 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRVAIKHLNLSKINTHTPKFKSQLNREIEILKFINHENVVEIYDIFYTKDQQLFFILELANG--GELYNKIGFNEP
|......|.| |..|| ...|.||..|||| ..             .. |||.|||  .|.|.| .||.|..  . |....|...|  |.|.  |  . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGR

L-----LNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIKITDFGLARFIHEGELAKTLCGSPLYVAPEVILSLHHKNKYGTNSSS
      ..| . .|...||..|. |.||.|| ||||||||||.|.       |||.||||||..      .|.||.| |.||||.               
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL---------------

SSQSPTKDINSVGYGK-SCDAWSLGAILYIVLCGTPPFDDDDDEEMSTPQLFEKIVSGNYRVEKLEKSLISSSAADLVKGLLTVDPDKRLTVEQALN---
            |||| .|| ||.| |||. ||| |||.          ..|.||.              |..| |.....|..||.||.|. .||.   
------------GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

----HPWI
    |||.
DIKCHPWF

Kinase FHAK1.AA AGC 180-472 25 3.6e-99 256.41 In-house 1-395 (395) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-395/395
Sequence Identity: 25% (109 aa)

YDFIKELGSGNFSVVYEGVNK------NTGKRVAIKHLNLSK---INT--HTPKFKSQ--------LNREIEILKFIN----------HENVVE-IYDIF
..|.| .| | |. ||    |       |||  |.| |. ..   |.      . ..         . .| .||. .|          | ..|   .  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YTKDQ-QLFFILELAN---------GG-ELYNKI-GF-NEPLLNENQSKFIFKQ-------ILNAVSYLHS-KGIAHRD-LKPENILFDSYGDDYLKIKI
 .||  .|.|..|...         || ||.  . |  .|  ..|....|.. .       |. |. |||| .|| ||| |||||||.|.       ||.
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED----GHIKL

TDFGLARFI---------------------------------------------------HEGELAKTLCG--SPLYVAPEVILSLHHKNKYGTNSSSSS
|||||.  .                                                   .......|.||  .| |.|||..                 
TDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----------------

QSPTKDINSVGYGKSCDAWS--LGAILYIVLCGTPPFDDDDDEEMS------TPQLFEKIVSGNYRVEKLEK------------SLISSSAADLVKGLLT
           |||.|| ||  ||...|  |.| ||| .|...| .        ..|.|| .|.|  .. .|            . .|. | ||.|.||.
-----------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQE-NRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLC

VDPDKRLT----------VEQALNHPWI
.||.|||.          .|.  |||| 
KDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase FHAK1.AA Pkinase 180-472 32 9.7e-99 339.14 Pfam 1-293 (293) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-293/293
Sequence Identity: 32% (105 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRVAIKHLNLSKINTHTPKFKSQLN-REIEILKFINHENVVEIYDIFYTKDQQLFFILELANGG----ELYNKIG-
| ... .|||.|..||....|.|||.||.| ....  ...  | .. .. .||.|.| .||.|.|..||.|.. .. . ...|...||    .|.  |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST

-FNEPL-LNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIKITDFGLARF--IHEGELAKTLCGSPLYVAPEVILSLHHKNKYGTN
  . .. . |.. ||...||| .. |.||.|| ||||||||||.|. |.   ..||.|||||..  .  .. ..|.||.| |.|||||.           
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----------

SSSSSQSPTKDINSVGYGKSCDAWSLGAILYIVLCGTPPFDDD--DDEEMSTPQLFEKIVSGNYRVEKLEKSLIS-----------------SSAADLVK
             . .||...| ||.| |||..||| |||...  .|. ..  |....| .. .. .  ... ||                 ... |..|
------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

GLLTVDPDKRLTVEQALNHPWI
..|..|| ||.| ||.|.|||.
WCLCKDPKKRPTAEQILQHPWF

Kinase FHAK1.AA CAMK-Unique 180-472 27 4.1e-96 317.79 In-house 1-363 (363) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-363/363
Sequence Identity: 27% (104 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRVAIKHLNL--SKINTHTP-------------KFKSQLNREIEILKFINHENVVEIYDI----FYTKDQ------
|.... .|.|||..|||. .. |||  |.|....   ...   .                 .| ||..|.|. .|.| ...||.    | ...       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------QLFFILELANGGELYNKIGFN-------------------EPLLNE--NQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDD----
         .. ..|...||.|. .|  .                   .  ..|  ... ||. ..| ||.|.||..| |||||.|||.. . ..|    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------YLKIKITDFGLARFIHEGELAK---TLCGSPLYVAPEVILSLHHKNKYGTNSSSSSQSPTKD--INSVGYGKSC----DAWSLGAILYIVLC
         ..||..||||.. ... .      | ||.|.|.|||.                  |. |.|  || ..|.  |    | ||||.|.|. ||
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKN------------YQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLC

GTPPFDDDDDE---EMSTPQLFEKIVSGNY-RVEKLEKSL---ISSSAADLVKGLLTVDPDKRLTVEQALNHPWI
| |||| ....   |     .||.| .|.| ....   ..   || .| |.||...|||||.|.. ...| |.||
GCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase FHAK1.AA Ciliate-E2a 180-472 32 6e-92 270.93 In-house 1-275 (275) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-275/275
Sequence Identity: 32% (100 aa)

YDFIKELGSGNFSVVYEGVNKNTGKR-VAIKHLNLSKINTHTPKFKSQLNREIEILKFINHENVVEIYDIFYTKDQQLFFILELANGGELYNKIGFNEPL
|.|||..|.||| .||    |.|||. ...|  .    .....|.  .. .|| |.. ..| |.  .|... ... ......|. .|||||.||  .  .
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKE--YFMNEINIMRQLDHPNIIKLYEVYEDEN-NYYLVMEYCEGGELYDKIKQCKRF

LNE-NQSKFIFKQIL-NAVSYLHSKGIAHRDLKPENILFDS-YGDDY--LKIKITDFGLARFI--HEGELAKTLCGSPLYVAPEVILSLHHKNKYGTNSS
  | .. . | .|.|  ...|.|...| |||||||||||..   ...  ..||| |||||.||   |..  .. ||.| ||||                 
FEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAP-----------------

SSSQSPTKDINSVG------YGKSCDAWSLGAILYIVLCGTPPFDDDDDEEMSTPQLFEKIVSGNYRVEKLE-KSLISSSAADLVKGLLTVDPDKRLTVE
         .|.        |...|| ||.|.|.|| |||.|||.  .     . . ....   ..  .  |  . .|... ||.|..| .|| ||.| .
-------EVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKT-----YNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQ

QALNHPWI
||||||| 
QALNHPWF

Kinase FHAK1.AA Ciliate-E2 180-472 26 2.4e-90 306.43 In-house 1-365 (365) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-365/365
Sequence Identity: 26% (107 aa)

YDFIKELGSGNFSVVYEGVNKNTGKR------------------VAIKHLNLSKINTHTPKFKSQ---LNREIE----------ILKFINHENVVEIYDI
|.||| .|.|||..||.. .....|.                  |.||  ..  ..    ....|   ..|||.          ||...|| |....|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYT-KDQQLFFILELANGGELYN------KIGFNEPL----LNENQSKFIFKQILN---------------AVSYLHSKG-IAHRDLKPENILFDSYGDD
|.. .|. .....|...||.|.       |  ..|.     ..|.. |.|.||||.               |. |||||. | |||.|||||||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

YLKIKITDFGLARFIHEG--------------------------------ELAKTLCGSPLYVAPEVILSLHHKNKYGTNSSSSSQSPTKDINSVGYGKS
   |||.||||......                                 ....|.||.| |.|||.. .    |                ... ||...
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---------------QKQKGYDYK

CDAWSLGAILYIVLCGTPPFDDDDDEEMSTPQLFEKIVSGNYRVEKLE--------------KSLISSSAADLVKG----LLTVDPDKRLT-VEQALNHP
|| |||| |||. |.| |||             ...|  ....  . |              .  .| .. || |     .| .||.||.|  ||.||||
CDIWSLGVILYEMLFGKPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP

WI
|.
WF

Kinase FHAK1.AA CAMKL 180-359 34 8.3e-76 241.37 In-house 1-207 (297) Show / Hide
Range on Protein: 180-359
Range on HMM: 1-207/297
Sequence Identity: 34% (72 aa)

YDFIKELGSGNFSVVYEGVN-KNTGKRVAIKHLNLSKIN--THTPKFKSQ--------LNREIEILKFIN---HENVVEIYDIFYTKDQ-----QLFFIL
|...|.|| |.|..|  ... ..||..|||| .. .||.  ... | |          . |||.|.| .|   |.|.. .|....|..      ... ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELANGGE--LYNKIG-FNEPL--LNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIKITDFGLARFIHE-----GELAKTLCGSPL
|.. |||  |...|    ..   . |.. ...|.||. ||.|.||.||.|||.||||||.|. |.   .|||.|||.. .. .     |.. || |||| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YVAPEVILS
| |||....
YMAPEIFQG

Kinase FHAK1.AA Ciliate-E2-Unclassified 180-472 26 2.3e-75 256.66 In-house 1-352 (352) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-352/352
Sequence Identity: 26% (98 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRV-------AIKHLNLSKINTHTPKFKSQLNREIE---------------ILKFINHENVVEIYDIFYTKDQQLF
| .|| .|.|.|..||. ..|...  .        |.. .  .|..    .. ..... .               ||. ..|...|  ...| ...| ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCF-QDKQNIY

FILELANGGELYNKIGFNEP----------------LLNENQSK-----FIFKQILNAVSYLHSKG-IAHRDLKPENILFDSYGDDYLKIKITDFGLARF
...|...||.| . |  ..                  . |.|.|     |.|.|||.. .|||.|. | |||.||||||||. |   ..|||.|||....
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKK

IHEG----------------ELAKTLCGSPLYV----APEVILSLHHKNKYGTNSSSSSQSPTKDINSVGYGKSCDAWSLGAILYIVLCGTPPFDDDDDE
. .                 ....| ||.| |     ||||. . .. ..                      ..|| |||| |||  | |..||.| ..|
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--------------------YKCDIWSLGVILYEMLFGYYPFYDNNCE

E---MSTP--------QLFEKIVSGNYRVEKLEK----SLISSSAADLVK----GLLTVDPDKRLTVEQALNHPWI
.   ..|.        ||...|  .|. . | ..      .| .|.|...     .| ..|.||.| ||.|||||.
QHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase FHAK1.AA CAMK1 180-362 40 2.3e-71 206.7 In-house 1-193 (276) Show / Hide
Range on Protein: 180-362
Range on HMM: 1-193/276
Sequence Identity: 40% (80 aa)

YDFIKELGSGNFSVVYEGVNKNT---GKRVAIKHLN-LSKINTHTP-KFKSQLNREIEILK---FINHENVVEIYDIFYTKDQQLFFILELANGGELYNK
| |.||.|.| ||.||....|.|   || .||| ..  . . ...  | . .| .||||.|    |.|.|.. .|... ...  . ...|| .||||  .
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDN-HFYLVMELVTGGELFDR

IGFNEPLLNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIK--ITDFGLARFIHEGE-LAKTLCGSPLYVAPEVILS---LHH
|  ..   .|..   | |||| || |.|||||.||||||||.|. .  .|  |||  | ||||.... ..| | || ||.| ||||||.      ..
IVEKG-NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDED-SKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY

Kinase FHAK1.AA MARK 180-359 40 4.8e-59 191.71 In-house 1-179 (262) Show / Hide
Range on Protein: 180-359
Range on HMM: 1-179/262
Sequence Identity: 40% (75 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRVAIKHLNLSKINTHTPKFKSQLNREIEILKFINHENVVEIYDIFY--TKDQQLFFILELANGGELYNKIGFN-E
| ..|..| |....|. ...|.||..|||| ..  |.|   |. .. . |||||.| ..|.|... ....   |. .|...|.|.| |||||. |     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLND--PQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

PLLNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIKITDFGLARFIHEGELAKTLCGSPLYVAPEVILS
  | |.  . ||.||. ||.|.|||.|.|||.|||||| |. |    .|||.|||... | .|.. .| ||.| | |||..|.
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGN--HNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLK

Kinase FHAK1.AA CAMK1 385-472 48 2.8e-39 111.79 In-house 192-276 (276) Show / Hide
Range on Protein: 385-472
Range on HMM: 192-276/276
Sequence Identity: 48% (44 aa)

GYGKSCDAWSLGAILYIVLCGTPPFDDDD-DEEMSTPQLFEKIVSGNYRVEKLEKSLISSS-AADLVKGLLTVDPDKRLTVEQALNHPWI
.|.|.|| || | |.|| ||| ||| |.. |.|.     |||| .. |.  . .   ||.. | |..|..|.||| ||.|.||.||||||
PYDKACDMWSIGVITYILLCGYPPFYDENVDNEL-----FEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase FHAK1.AA CAMKL 386-472 37 1.2e-22 68.93 In-house 213-297 (297) Show / Hide
Range on Protein: 386-472
Range on HMM: 213-297/297
Sequence Identity: 37% (34 aa)

YGKSCDAWSLGAILYIVLCGTPPFDDDDDEEM----STPQLFEKIVSGNYRVEKLEKSLISSSAADLVKGLLTVDPDKRLTVEQALNHPWI
.|.  | ||.| |||  .||. |||||...       .  |..|| .| |.      . .| .. || ...|.|.|.|| |..| .|||| 
DGPKVDIWSCGVILYAMVCGYLPFDDDTYN-KQGKDNI-YLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase FHAK1.AA MARK 386-472 35 7.1e-22 68.43 In-house 183-262 (262) Show / Hide
Range on Protein: 386-472
Range on HMM: 183-262/262
Sequence Identity: 35% (32 aa)

YGKSCDAWSLGAILYIVLCGTPPFDDDD--DEEMSTPQLFEKIVSGNYRVEKLEKSLISSSAADLVKGLLTVDPDKRLTVEQALNHPWI
.|.  | |||| .||. .||. |||.|.  ..|.     ..||..|.|..       .| .. .|.. ||||.|..| |.|. ..|||.
DGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKEL-----YKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase FHAK1.AA Pkinase_Tyr 180-340 28 5.2e-19 65.01 Pfam 1-165 (270) Show / Hide
Range on Protein: 180-340
Range on HMM: 1-165/270
Sequence Identity: 28% (49 aa)

YDFIKELGSGNFSVVYEGVNK----NTGKRVAIKHLNLSKINTHTPK--FKSQLNREIEILKFI-NHENVVEIYDIFYTKDQQ--LFFILELANGGELYN
  |.|.||.|.| .||.|. |    ||.  ||.| |.    ......  ..  . ||..|.| . .|.|.|  | . . ....  .. ..|.. .| |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

KIGFN---EPLLNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIKITDFGLARFIHEGE
    .   .. |.  .   .  || .. .||.||.. ||||   |.| ..   .  ..||.|||||| |.. .
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NN-VVKICDFGLARDIYNDD

Kinase FHAK1.AA TyrKc 180-472 22 2.2e-15 26.06 SMART 1-280 (280) Show / Hide
Range on Protein: 180-472
Range on HMM: 1-280/280
Sequence Identity: 22% (72 aa)

YDFIKELGSGNFSVVYEGVNKNTGKRVAIKHLNLSKINTHTPKFKSQLNREIEILKFI--NHENVVEIYDIFYTK------DQQLFFILELANGGELYNK
  ..|.||.|.| .||.|. |     ||.| |. ..        .  . ||..|.. .  .|.|.| .| .  ..      ...|. ..|.. .| | . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IGFNEPLLNENQSKFIFKQILNAVSYLHSKGIAHRDLKPENILFDSYGDDYLKIKITDFGLARFIHEG-------ELAKT----LCG--SPL-YVAPEVI
.  ..| |.  .   .  || .  .|||||.. ||||   |.| .. .     .||.||||.|.|...       .  ..     .    |.   |||.|
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

LSLHHKNKYGTNSSSSSQSPTKDINSVGYGKSCDAWSLGAILY--IVLCGTPPFDDDDDEEMSTPQLFEKIVSGNYRVEKLEKSL------ISSSAADLV
     ..|. | |                    | || |  ..    ....|. ..     ||  ...|.. .| || .. .  .       ..   .. 
----NYGKFTTKS--------------------DVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQG-YRMPQPPNDYPMSFVCCPDEMYQIM

KGLLTVDPDKRLTVEQALNHPWI
|     ||..| | ..   |  .
KQCWHEDPEDRPTFSEI--HECF