Gene FHAK5 (Slime mold)

FHAK5

Species: Slime mold
Alias: FHAK5, DDB0216333, DdisK042
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: RAD53

Sequence

Name Sequence Type Origin Length Description Download
FHAK5.AA Protein None 712 None Fasta, JSON
FHAK5.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of FHAK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA FHAK5.AA FHA 46-117 30 1.4e-12 51.66 Pfam 1-73 (73) Show / Hide 
Range on Protein: 46-117
Range on HMM: 1-73/73
Sequence Identity: 30% (24 aa)

ITFGRLKDSTVHYN-DKS-ISGSHCKITRESNDDDGVVIAFIYD--NSTNGTFI--DNIKVGKGSRCLLASGQEISLT
.|.|| .|. .  . |.| .|. || | | ..|..     .| |  .||||||.  .. ....| .. | .| .|.. 
WTIGRDPDCDIVLDNDPSFVSRHHCEI-R-RYDNG---RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG
FHA FHAK5.AA FHA 45-100 27 4.8e-10 40.61 SMART 1-49 (49) Show / Hide 
Range on Protein: 45-100
Range on HMM: 1-49/49
Sequence Identity: 27% (16 aa)

VITFGRLKDSTVHYNDKSISGSHCKITRESNDDDGVVIAFIYDNS---TNGTFIDNIKV
..|.|| . . .   ..|||  || |. ...        .| |..   ||||.... .|
TWTIGRHS-CDIQLPHPSISRHHCQIR-DGD--------YIIDLGEHSTNGTYVNGRRV
Kinase FHAK5.AA RAD53 145-411 47 1.2e-206 622.17 In-house 1-305 (305) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-305/305
Sequence Identity: 47% (146 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYF---MNSSARKDSLMDEVNILRGLSHPNIIQIIEVFEN-EKVLSLILELVECGELLNDIV-SN
| ....||.|||.|||||.|..|. |.|.||.||||.|   |......|..|.||.||..|.||.||.|...|.. .|.....|||...|||.|.|| ..
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

LF---YTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQ-------------NDAIKLTDFGLSRTVSDGSFMKTMCGTPQYLAPEILTS
..   ..||..|..|.|..|.|.|||..||.||||||||||..|.....             ...||.||||||..|..|||||||||||||.|||..||
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

S-----GGHN------GYGLEVDCWSMGAILYIMLCGYPPFDDS-----REVSIFEQIRN-AKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNII
.     ....      ||. .|||||||.||||.|||||||.|.     .....||||.| .|..|....|...|||||||||..|||||.||||.....
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

QHPWF
.|||.
NHPWM
Kinase FHAK5.AA CAMK1 145-411 41 4.7e-138 403.93 In-house 1-276 (276) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-276/276
Sequence Identity: 41% (117 aa)

YFIGEMLGQGNFATVKLAVERTT---GVKYAVKIVDKKKYFMNSSAR--KDSLMDEVNILR--G-LSHPNIIQIIEVFENEKVLSLILELVECGELLNDI
| .|...| | |..|.|.... |   | .||.|. || | ||  . .  ...|. |..|..  . ..|||||...|..| .. . |..|||  |||.  |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

VSNLFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIK--LTDFGLSRTVSDGS-FMKTMCGTPQYLAPEILTS-SGGHNGYGL
| . .|||..| .. .||.. | |.| |||.||||||||.|.. | ..    ||  . |||||. ..... .|||.|||| | |||.|.  .    .|. 
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDED--SKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKK--DKPYDK

EVDCWSMGAILYIMLCGYPPFDDSR-EVSIFEQIRNAKFEFDPEDWSSVSEE-AKDLIKRLLCVDPHKRYTCNNIIQHPWF
..|.|| | |.||.||||||| |.. .  .||.| ....||.   | ..|.. |||.|| .|.||| |||||  ...|||.
ACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase FHAK5.AA CAMK 150-411 28 2.6e-133 432.2 In-house 1-425 (425) Show / Hide 
Range on Protein: 150-411
Range on HMM: 1-425/425
Sequence Identity: 28% (119 aa)

MLGQGNFATVKLAVER-TTG-----------VKYAVKIVDKKKYFMN-----------------------SSARKDSLMDEVNILRGLS-------HPNI
 ||.|.|..|||.... |||           .|.|.||.||||   .                       .   ..... |..|.. |.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQIIEVFEN-------------------EKVLSLIL---ELVECGEL----LNDIVSNLF---------------YTEDKAKTLFRQIVDGVLYLHNKGI
|...||.|.                   .| . ...   |... |||    .. ||..                 .||. |...||||...| |.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENILLKHKNFNQN------------DAIKLTDFGLSRTVSD------------------------GSFMKTMCGTPQYLA-PEILTSSGG---
.||||||||||| ..| ...              ||..|||... . .                        |  |||.|||| | | ||.| ..|.   
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------HNGYGLEVDCWSMGAILYIMLCGYPPFDDS-------------REVSIFEQIRNAKFEFDPED------------WSSVSEE--------AKD
       . .|| ..|.||.| ||||||||||||...              .  .||.|...|..|.|.             |...|.|        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIKRLLCVDPHKRYTCNNIIQHPWF
||...|.||| ||.|.  . .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase FHAK5.AA Ciliate-E2a 145-411 40 6.5e-116 342.66 In-house 1-275 (275) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-275/275
Sequence Identity: 40% (111 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGLSHPNIIQIIEVFENEKVLSLILELVECGELLNDIVSNL-FYT
|..  ..|.|||. |.||  . || ..|.|...|| |  ..   | ..|.|.||.| |.|||||...||.|.|. . |..|..| |||.. |. .  | .
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMY--QQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFE

E-DKAKTLFRQIV-DGVLYLHNKGIAHRDLKPENILLKHKNFN--QNDAIKLTDFGLSRTV--SDGSFMKTMCGTPQYLAPEILTSSG--GHNGYGLEVD
|  ... . .|.  .|..|.|...| ||||||||||.| ...|  ||  ||. ||||.. .   .. .|...|||| |.|||.| .     |. |.  .|
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCD

CWSMGAILYIMLCGYPPFDDSREVSIFEQIRNAKFEFDPED-WSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWF
 || |.|.||.|||.|||.   .  |..|... |. |.  . |. .| |.|||.|..| .|| ||.|.. . .||||
MWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase FHAK5.AA CDPK 145-411 37 2.1e-108 333.55 In-house 1-271 (271) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-271/271
Sequence Identity: 37% (105 aa)

YFIGEMLGQGNFATVKLAVER-TTGVKY-AVKIVDKK-----KYFMNSSARKDSLMDEVNILRGLSHPNIIQIIEVFENEKVLSLILE--LVECGELLND
|.|.. ||.|.| .|......  |...  |.||. |.     ..       ....  |..||. | |||||.| |... ||   ...|  ... |||.  
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQ-------QQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDY

IVSNLFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQN--DAIKLTDFGLSRTVSD-----GSFMKTMCGTPQYLAPEILTSSGGHN
|...  .|| .|   .|||.  | | |...| ||||||||||.. |. ...    ||. |.|.|.         .  |...|||| |.|||.|     ..
IIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQ----KK

GYGLEVDCWSMGAILYIMLCGYPPFDDSREVSIFEQIRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWF
 |  ..| || | ||||.|||||||    .  |.|.... |..|. ..|...|.||||||...||.|| ||.... . |||||
-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase FHAK5.AA CAMKL 145-411 37 1.4e-107 344.38 In-house 1-297 (297) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-297/297
Sequence Identity: 37% (116 aa)

YFIGEMLGQGNFATVKLAVE-RTTGVKYAVKIVDKKKYFMNSSARKD------SLMD----EVNILRGLS---HPNIIQIIEVFENEKV------LSLIL
| ||. ||.|.|..||||.  ||||.|.|.||.||||  ..  ..|       . ..    |..|.. |.   |||||.. ||.|...       . |..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVECGE--LLNDIVSNLF----YTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSD-----GSFMKTMCGTP
|... ||  |.. ||..       .|. |. .|||||..| |.|..||.|||.||||||| ... |    ||..|||.|    .     | ..|| ||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

QYLAPEILTS-SGGHNGYGLEVDCWSMGAILYIMLCGYPPFDDS--------REVSIFEQIRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNN
 | ||||. .    .  .| .||.||.| ||| |.||| ||||              ...|.   .....  |..|| ...|||...| |.| ||.|. .
PYMAPEIFQGNNKPY--DGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPI--WYHVS-DCRDLIRKMLQVNPEKRPTIHQ

IIQHPWF
| .|||.
IMNHPWM
Kinase FHAK5.AA S_TKc 145-411 34 7.50000000001e-107 362.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-231/231
Sequence Identity: 34% (98 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGLSHPNIIQIIEVFENEKVLSLILELVEC--GELLNDIVSNLF-
| |.. .|.| |..|...... || ..|.||..            .... |..||.   ||||.....||.. . | ...|...   |.|.  |...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----YTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSDGSFMKTMCGTPQYLAPEILTSSGGHNGYGL-EVD
     ..|  |. ...||.... |.|..|| ||||||||||| .        ||..||||.| .      .|.|||| |.|||.|       |||  ..|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCD

CWSMGAILYIMLCGYPPFDDSREVSIFEQIRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQ-------HPWF
 || | |||.||||||||.   .  .|..|.              |.||||.|...|..|| ||.|.  . |       ||||
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase FHAK5.AA Pkinase 145-411 36 2.9e-100 344.19 Pfam 1-293 (293) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-293/293
Sequence Identity: 36% (109 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGLSHPNIIQIIEVFENEKVLSLILELVECG----ELLNDIVS--
| ||. .|.|.|..|...... || ..||||..|..  ..   ..  |  |. |.. |.||||......||... . ...|..|.|    .|  |..|  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTW

-NLFY--TEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRT--VSDGSFMKTMCGTPQYLAPEILTSSGGHNGYGLE
 .  .  .|. .|  ..||. |. |.|..|| ||||||||||.. .| . .. .|..||||..      .| |.| |||| |.|||..    |...|| .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPK

VDCWSMGAILYIMLCGYPPFDDS------REVSIFEQIRNAKFEFDPEDWSSVS-----------------EEAKDLIKRLLCVDPHKRYTCNNIIQHPW
|| ||.| |||.||||.|||...      ..  ....|. ....|| . |.|.|                 ||.||.||..||.||.||.|.  | ||||
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase FHAK5.AA DCAMKL 145-411 40 2.8e-98 306.36 In-house 1-279 (279) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-279/279
Sequence Identity: 40% (116 aa)

YFIGEMLGQGNFATVKLAVERTTG-VKYAVKI-----------------VDKKKYFMNSSARKDSLMD-EVNILRGLSHPNIIQIIEVFENEKVLSLILE
| || . | ||||.|.....|.||  ||| ||                 .||.|        |  . | || |.. ..||.|||..|... |. . |..|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKC-----KGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVME

LVECGELLNDIVSNLFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSD-GSFMKTMCGTPQYLAPEILTSS
.|. | | . |..|  .||  |  . ...     ||| ..| |||.|||| |.. . .     .|| ||||   | .    . | |||| | |||||   
YVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEIL---

GGHNGYGLEVDCWSMGAILYIMLCGYPPFDDS--REVSIFEQIRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWF
    |||..|| |. | ||||.|||.|||  .   .   |.||  .||||.   |. .|  |||||...| ||| ||||   | |||| 
-METGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase FHAK5.AA MARK 145-411 39 3.2e-93 305.07 In-house 1-262 (262) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-262/262
Sequence Identity: 39% (108 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGLSHPNIIQIIEVFE--NEKV-LSLILELVECGELLNDIVSN--
| ..  .|.|..|.||||. . ||.|.|.||..|.| . . . ..  .| |..|.. |.|||||.  .|.|  .|.  . ||.|... |||.. |..   
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKN--VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

LFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSDGSFMKTMCGTPQYLAPEILTSSGGHNGYGLEVDCWSM
   .|. |...||||| .| |.|.|.|.|||.||||||. ...   |  ||..|||.|. .  |.  .| |||| | ||||.    .   .| .|| ||.
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENG---NHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFL---KKPYDGPKVDIWSL

GAILYIMLCGYPPFDDSR--EVSIFEQIRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWF
| .||.|.||| |||..   .. ....|.. |..  |     || |...||.||| |.|..| |. .| .|||.
GVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCH---VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase FHAK5.AA CAMK-Unique 145-411 26 5.2e-93 307.39 In-house 1-363 (363) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-363/363
Sequence Identity: 26% (99 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDK-----KKYFMN----------SSARKDSLMDEVNILRGLSHPNIIQIIEV----FENEK-------
|  .. .|.|||  |. .  |.||.|.|.|.| |     ||.  .           . |  .|. |..|.. ..|||||.. ..    |. .|       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------VLSLILELVECGELLNDIVS--------------------NLFYTE--DKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQ---
         . ...|....|.|.  |..                    .  ..|    . .......  | |.|...| |||||.|||... ..|.    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVC-YSFKDNNH

---------NDAIKLTDFGLSRTVS-DGSF--MKTMCGTPQYLAP--------------EILTSSGGHNGYGLEV----DCWSMGAILYIMLCGYPPFDD
         |  |||.||||.. ..   .   |.|||||| |.||              |..    .  .|.  .    |.||.|.|.|.||||.|||| 
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVI----NMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDC

SREV--------SIFEQIRNAKF-EFDPEDWSS---VSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWF
. |         .||| |. ... .|| . |..   .|.||||..|... ||| .| .......|.|.
ECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase FHAK5.AA Ciliate-E2 145-411 27 2.5e-92 313.02 In-house 1-365 (365) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-365/365
Sequence Identity: 27% (107 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKI-------------VDKKKYFMNSS--ARKDSLMDEVNILR----------------GLSHPNIIQIIEV
| . ...|||||..|...  . .. ..| ||             |..|.| |..     . ... | .|.|                 |.|||||...|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NEKVLSLILELVECGELLNDIVSN-LF----------YTEDKAKTLFRQIVD---------------GVLYLHNKG-IAHRDLKPENILLKHKNFN
|.  ... . |..|... |.|.  | .| ..          .|| ..|....||..               .. |||.|. | |||.||||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

QNDAIKLTDFGLSRTVSD-----------GSFMKTM----------------------CGTPQYLAPEILTSSG-----GHNGYGLEVDCWSMGAILYIM
    ||..|||||. ..|           . .|                         |||| |.||||| . .     ...||. ..| ||.| |||.|
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

LCGYPPFDDSREVSIFEQIRNAKFEFDPE--------------DWSSVSEEAKDLIKR----LLCVDPHKRYT-CNNIIQHPWF
|.|.|||        ..|| . |..|...              .| ..|.|.|||||.    .|..|| ||.|  . |..||||
LFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase FHAK5.AA TyrKc 145-411 21 1.8e-14 11.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 145-411
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YFIGEMLGQGNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGL--SHPNIIQIIEVFENE-------KVLSLILELVECGELLND
   |..|| |.| .| ... .   .. ||| . . .        .  .|.| .|.. |  .||||.... |   .       . | ...|... | |.. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IVSNL--FYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSDG------SFMKTM----CGTP----QYLAPE
. ..   . ..|. .  . || .|  ||| |.. ||||   |.|.....      .| .|||||| . |.      . ....    .|        .|||
LRKHRPKLCMKDLLSFCW-QIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

ILTSSGGHNGYGLEVDCWSMGAILY-IMLCGYPPFDD-----SREVSIFEQIRNAKFEFDPED-----WSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQH
 .     .. .  . | || |  .. |.  | .|  .          ..|.... .    |..         ..|  ...|.    ||..| | ..|  |
CI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

PWF
  |
ECF
Kinase FHAK5.AA Pkinase_Tyr 145-234 23 1.7e-11 39.58 Pfam 1-96 (270) Show / Hide 
Range on Protein: 145-234
Range on HMM: 1-96/270
Sequence Identity: 23% (24 aa)

YFIGEMLGQGNFATVKLAVER----TTGVKYAVKIVDKKKYFMNSSAR---KDSLMDEVNILRGL-SHPNIIQIIEVFE-NEKV--LSLILELVECGELL
  .|..||.|.| .|.... .     |... |||.. |     ... .   ....| |..|.. | .||||.. . |    ..   . ...|....| ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

N
.
D
Kinase FHAK5.AA Pkinase_Tyr 252-303 37 0.000314 14.95 Pfam 118-165 (270) Show / Hide 
Range on Protein: 252-303
Range on HMM: 118-165/270
Sequence Identity: 37% (20 aa)

RQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTV-SDG
.|| .|  ||..|.. ||||   |.|...     |  .| .||||.|.. .|.
WQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDD
Zf-CCHH FHAK5.AA zf-CCHH 685-710 50 5.8e-12 50.68 Pfam 1-26 (26) Show / Hide 
Range on Protein: 685-710
Range on HMM: 1-26/26
Sequence Identity: 50% (13 aa)

PKCQYDPNCYRKNPQHLRDFYHTVSS
|.|.| .||||.||||.|...| ...
PHCPYGANCYRRNPQHFREYSHPHDQ