MARK-A

Species: Slime mold
Alias: mrkA, MARK-A, DdisK034, DDB0216369, mark
External Links: DictyBase Link ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
MARK-A.AA Protein None 1060 None Fasta, JSON
MARK-A.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of MARK-A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MARK-A.AA MARK 109-361 55 4.7e-166 546.61 In-house 1-262 (262) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-262/262
Sequence Identity: 55% (145 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDP-ETLKMVQREVRIMKLLHHPNIIRLYEVIE--TSRA-LYLIMEYAGEGEVMDFMIAH--G
| ..|||| | ..||||. ||.   .||||||..| ||.. ...|.|.||..|||.|.|||||.|..|||  |..  .|||||||..||..|...||  |
YKMLKTIGHGSYAKVKLACHKHTG-RKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

VLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNR--QIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVL
 |.|. ||..|.|||||.||||||. ||||.||||.|.|.|.  .|||||||.|. ..||. |.||||.| |..||..|.|.|.|| ||.||.||||...
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VTGYLPFDGDN--YVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
|.||.|||||.  |.||..|||.|.|.||... .||..||.|.|.|.|..|.|.||| .|||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase MARK-A.AA CAMKL 109-361 45 3e-163 524.96 In-house 1-297 (297) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-297/297
Sequence Identity: 45% (136 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIIN--KGKLDPETLKM-----------VQREVRIMKLLH---HPNIIRLYEVIETSRA------LYLIM
| ..||.|.| ||||||. |.....||||||||.  | ..|| ..|.           ..||..|||.|.   |||||.|||||||..       .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAGEGE--VMDFMIAH----GVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNR--QIKIIDFGLSNVFTP-----GSYLKTFCGSPTYA
||.. ||   .|. ..|    | ..|..|| .|.|||||.|||||.. ||||.||||.|||.|   .|||||||.|| ..|     |  |||||||| |.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPELILR--KEYNGPSVDVWSMGVVLFVLVTGYLPFDGDNYV---------ELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
.||....  |.|.|| ||.||.||.|...|.||||||.|.|          .. .... ....|....  .|..||..||.|.|.||.|...| ||||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase MARK-A.AA AMPK 109-361 54 1.2e-154 462.51 In-house 1-254 (254) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-254/254
Sequence Identity: 54% (139 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKL-DPETLKMVQREVRIMKLLHHPNIIRLYEVI-ETSRALYLIMEYAGEGEVMDFMIAHGVLTE
|.. ||||.| |||||.|.| .. .|||||||.|| |. | .. . .|||..|.||. ||.||.||||| || . ....|||.  ||  |. . || |.|
YIIGKTIGEGTFGKVKMGTH-ILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

SQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLP
 .|. || ||.|.. |||    |||||||||||||.| .||| ||||||. . | .||| |||| ||.||.|  | |.|| ||.|| ||.|.... ||||
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
|| .|  .|..||..| |.||..|. |.|.||..|| ||| ||.| ..| ||||.
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase MARK-A.AA CAMK 114-361 32 1.8e-145 472.11 In-house 1-425 (425) Show / Hide
Range on Protein: 114-361
Range on HMM: 1-425/425
Sequence Identity: 32% (140 aa)

TIGRGQFGKVKLGYHKKIPN-----------EKVAIKIINKGKLD--------------------------PETLKMVQREVRIMKL-------LHHPNI
|.|||.||||||..||. ..           .|||||||.| ||.                          |...|.|.||..|||.       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYEVIE------------TSRA--------LYLIM---EYAGEG----EVMDFMIAH---------------GVLTESQARTFFTQIVSAINYCHSKR
|.||||.|            | .         .|..|   ||.  |    .. |. ..|               | .||..||..| ||.||..||||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

AVHRDLKPENLLLDCN-----------------RQIKIIDFGLSNVFTP------------------------GSYLKTFCGSPTYAS-PELILR-----
 |||||||||.||| |                  .|||||||..|.|.|                        |  .|||||.| |.. ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KEYNGPSVDVWSMGVVLFVLVTGYLPFDGD-------------NYVELFQKILAGNYT-IPSYLTH-----------------------ECK
        |.| ||..|.||.||.|.....||.||.||             |. |||.||..|.|. .|.|...                       |||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

SLISRMLVVDPDKRATMEEIINHPWL
.||..||.|||.||.| |.. ||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase MARK-A.AA NuaK 109-361 46 3.3e-133 352.73 In-house 1-252 (252) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-252/252
Sequence Identity: 46% (119 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKL-DPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTES
| ..|| |.| .|||||.. ..  .| |||| | | |  |.. .  . ||..||  |.||.||  ||| | .  . ..||||  ||  |..   ..|.| 
YEFQKTLGKGTYGKVKLATEHSTGRE-VAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPER

QARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLPF
 || || |||||. |||  | .||||| || ||| |  .|| ||||||..  .  |.|||||| ||||| .  . |.|| || ||.||.|...| | .||
EARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPF

DGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
||... .| . |  |.|  |      |. ||  || |.|..|||...| .|.|.
DGHDFKHLVKQISQGAYYEPCKPSDACM-LIRWMLMVNPRRRATIYDICHHWWV

Kinase MARK-A.AA QIK 109-361 48 8.9e-133 447.41 In-house 1-272 (272) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-272/272
Sequence Identity: 48% (133 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGV-----
| . .|||.| |. |||. | .|  .||||||| | .|| | |. . ||| |||.| ||.||.||.|.|| ...|...||. .||  | ...||      
YDIERTIGKGNFAVVKLARH-RITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSV
               ..|..||  |.||.||. |||..  |||||| ||.||| |  |||.|||.|| |..|  |.|.|||| || ||. . |||.|| |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DVWSMGVVLFVLVTGYLPFDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
|.|||||||.|||.| |||||..  .| |..| | . || ..  .| .|| .||||||..| |.. |..|.|.
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase MARK-A.AA S_TKc 109-361 36 3.8e-110 373.15 SMART 1-231 (231) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGE--GEVMDFMIAHGV---
| ....||.| ||||....|||  ...||||||.         ....||..|.|  |||||..||.|...   ||..|||..   |...|..  .|    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVL
   ..| .|| .. ||..|..||||.. .||||||||.|||   .|||.||||. ..      .||||.| | .||..    |.....|.|| |..|. .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VTGYLPFDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIIN-------HPWL
..|| ||.  .. ..|.||.          ..|.|..|...|..||.|| |  |. .       |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase MARK-A.AA RAD53 109-361 35 2.1e-108 324.09 In-house 1-305 (305) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-305/305
Sequence Identity: 35% (108 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGK------LDPETLKMVQREVRIMKLLHHPNIIRLYEVIET-SRALYLIMEYAGEGEVMDFMIAH
|...|..|.| ||.|||.| ||   .|||||||.| |       .. . . |..||.|.| |.||.|||.|....| .. .|...|... || ... ...
YYMSKELGSGNFGTVKLAYEKK-TCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSN

GV----LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNR------------------QIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELIL
.     ..|......| |.. |..| |..  .|||||||| |.. ..                  .||| ||||| .   ||..||.||.|.|  || |.
KRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVIT

RK---------------EYNGPSVDVWSMGVVLFVLVTGYLPFDGD-----NYVELFQKILA-GNYTI----PSYLTHECKSLISRMLVVDPDKRATMEE
 |               .| ...||.||||..|... .||.||. |       . ||..|.  |.|       .  . | |.||..||.|||.|| | .|
SKGHNCYHENEERQVQVGY-TKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDE

IINHPWL
..||||.
ALNHPWM

Kinase MARK-A.AA BRSK 109-361 47 1.8e-106 360.05 In-house 1-254 (254) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-254/254
Sequence Identity: 47% (122 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLD--PETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTE
| . || |.|| |.|||| | ..  .||||||||| ||   .  |. | ||. ||||  ||.....|.| |... ||||.|.   ||  |...  | || 
YRLEKTLGKGQTGLVKLGVH-CVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTP

SQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLP
  || || ||.||...|||.   ||||||||||||  ..||| |||.  .   .. | | |||| ||.|| |   .| |   |||| ||.|. | .| ||
KEARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALP

FDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
|| ||  .|  |.  | . .| .    | .|   |. |||||| ...||  ||| 
FDDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY

Kinase MARK-A.AA Pkinase 109-361 34 6.2e-104 356.39 Pfam 1-293 (293) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQR--EVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEG----EVMDFMI--A
| ....||.| ||.|....||. .  .||.|||.| . ... ..   |  |..||| |.||||.|||.. |... .|..|||.. |    . .|..   .
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HGVL--TESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQI----KIIDFGLSNV--FTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWS
||..  .| ... ...||.....||||.. .||||||||.|.| | .|    ||.||||. .    ..| ..||||.| |..||.|.  .| ||.||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

MGVVLFVLVTGYLPFDGD------NYVELFQKILAGNYTIPSYLT---------------------HECKSLISRMLVVDPDKRATMEEIINHPWL
.|..|. ...|..||.|.      .  .....|. . .  ... .                      |||..|...| .|| || | |.| .|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase MARK-A.AA SNRK 109-361 47 5.6e-99 324.76 In-house 1-254 (254) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-254/254
Sequence Identity: 47% (120 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGV-LTES
| . ||.||| |  |||  |     ||||.|.| | |.|  .   . .||| |||  ||||.||||||.|   ||||.|    ... |... |   | |.
YDLEKTLGRGHFAVVKLARH-VFTGEKVAVKVIDKTKMDEVSKAHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGYDMYDYIMKHEKGLCED

QARTFFTQIVSAINYCHSKRAVHRDLKPENLL-LDCNRQIKIIDFGLSNVFTPGSYLKTFCGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLP
 ||..| ||. ||.||| .. ||||||||| .  .    .|. ||| || | ||  |.|.|||  |. ||..|  .|  | ||.||.||.|..|| | .|
LARKYFCQIMHAIDYCHQLHVVHRDLKPENVVFFEKQGMVKLTDFGFSNKFMPGEKLETSCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAP

FDGDNYVELFQKILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
|.  |  |   .|.   ||.|. . .||. || .||| || |||..||| .|.|.
FQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV

Kinase MARK-A.AA TSSK 109-361 37 2.1e-98 323.55 In-house 1-289 (289) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-289/289
Sequence Identity: 37% (108 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEK---------------VAIKIINKGKLDPE-TLKMVQREVRIMKL-LHHPNIIRLYEVIETSR-ALYLIMEYAG
| | |.||.| ..||...|.||   ..               ||||||.. |  .. . |   ||  ||.  |.|||||..|| .||..   |..|||| 
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

EGEVMDFMIAH------GVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS------YLKTFCGSPTYASPELI
 | . ... ..      | |.|.|||..| |.|||. ||||.  |||||| ||.||| .. ||..||| ........       .||||||  ||.|| .
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

LRKEYNGPSVDVWSMGVVLFVLVTGYLPFDG--DNYVELFQKIL--AGNYTI--PSYLTHECKSLISRMLVVDPDKRATMEEIINHPWL
. ..|..  .|||||||.|...|.| .|||    |   . . .     ....     .. |||.||..||  .| .|....||..|.|.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM

Kinase MARK-A.AA TyrKc 109-361 27 1.9e-30 108.36 SMART 1-280 (280) Show / Hide
Range on Protein: 109-361
Range on HMM: 1-280/280
Sequence Identity: 27% (81 aa)

YLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLL--HHPNIIRLYEVIETS-------RALYLIMEYAGEGEVMDFMI
   .|..|.|.||.| .|  |    ..||.| .....     ...  || |||. |  |||||.||| |. ..         |...|||.  |   |.  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AHGV-LTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPG-------SYLKTFC--GSPT-----YASPELILRKEYN
.|.  |. ..   | .|| .  .| |||. .||||   | |.. |...|| |||||   . .       .| ..    |. |       .|| |  ....
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GPSVDVWSMGVVLF-VLVTGYLPFDG-----DNYVELFQKILAGNY-TIPSY--------LTHECKSLISRMLVVDPDKRATMEEIINHPWL
 .  |||| ||... ..  |  |  |      .  |..... .|..  .| .         . |  .....    ||..| |..||  |  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase MARK-A.AA Pkinase_Tyr 109-254 34 1.7e-27 93.78 Pfam 1-158 (270) Show / Hide
Range on Protein: 109-254
Range on HMM: 1-158/270
Sequence Identity: 34% (55 aa)

YLVIKTIGRGQFGKVKLGYHK---KIPNEKVAIKIINKGKLDPET--LKMVQREVRIMKLL-HHPNIIRLYEVIE-TSRA--LYLIMEYAGEGEVMDFMI
   .|..|.|.||.|..|. |   . .. .||.|.. | . ..|   ...  ||..||| | |||||.||| |.   ..   .|..|||.  |   |.  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AH----GVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLS
.|    . || ..   . .|| .. .| .||. .||||   | |...|...|| ||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

UBA_CAMKL MARK-A.AA UBA_CAMKL 490-527 48 1.1e-15 54.33 In-house 1-41 (41) Show / Hide
Range on Protein: 490-527
Range on HMM: 1-41/41
Sequence Identity: 48% (20 aa)

DQEIIEELVGL--GFEREELCNSIRQNKY-NDAASTYFLLQ
|.|||.|.. .  || |||...|.|.||| |..  ||.||.
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL

UBA MARK-A.AA UBA 490-527 28 5.8e-08 33.71 SMART 1-38 (38) Show / Hide
Range on Protein: 490-527
Range on HMM: 1-38/38
Sequence Identity: 28% (11 aa)

DQEIIEELVGLGFEREELCNSIRQNKYNDAASTYFLLQ
..|.|..|...|| |||.  . |....|. . ...|..
YEEKIDQLMEMGFDREECVQALRACNWNVEMAMNWLFS

UBA MARK-A.AA UBA 489-525 21 0.000612 18.09 Pfam 1-38 (38) Show / Hide
Range on Protein: 489-525
Range on HMM: 1-38/38
Sequence Identity: 21% (8 aa)

LDQEIIEELVGL-GFEREELCNSIRQNKYNDAASTYFL
 |.|....|. . ||....     |....| .. ...|
IDEEMVKQLMEMTGFSMMQCKKALRACNNNVERAVEWL

KA1 MARK-A.AA KA1 1011-1057 43 8e-24 83.08 Pfam 1-48 (48) Show / Hide
Range on Protein: 1011-1057
Range on HMM: 1-48/48
Sequence Identity: 43% (21 aa)

ETEGVRFSIEICRLP-RLSVNGLKFKRIGGSSWRYKSICKDLLSQMKL
|.| |.| |..|..| ||...|..|||..|..| ||..|...|..|.|
EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL