Gene MARK-B (Slime mold)
MARK-B
Sequence
Protein domains of MARK-B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MARK-B.AA | MARK | 65-320 | 45 | 3.1e-146 | 480.87 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-262/262 Sequence Identity: 45% (120 aa) YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRI---KERKEIEREISILKRLKHDNIIQLHDAIYEDDVGR-ICLILELVSGGELFDYIVAR--GR | ..|||| |. .||| .....||...|||| ..... ...|...|||.|.|.|.| |||.|...| .|. .. |.||.|..|||||.|||.|. || YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDG--NLKISDFGYSNIIKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMV |.|.| |..|||..... ||||....|||.|.||.|.||.| | ||.|||.|..|.||..|.||||.| |..|||.| |.|.| .|||||.||.||.|| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGQLPWTLTDGVQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV .|..|. .. ...| . . |||....|.| .|.. ..||.|.... | ||.|..|| | |. CGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | MARK-B.AA | CAMKL | 65-320 | 40 | 4.7e-138 | 443.23 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-297/297 Sequence Identity: 40% (121 aa) YLLGKTIGSGTSSKVKIGTN-ILTGKQYAIKITKPKRIK--------------ERKE-IEREISILKRLK---HDNIIQLHDAIYEDDV----GRICLIL | .|||.| |. .||| .|. ..||...|||| . |.|. |... |.|||.|.|.|. | |||.|.. |. .. . |.|.. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELVSGGE--LFDYIVAR----GRLSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDG--NLKISDFGYSNIIKP-----GNLLSTFCGSPVYA |..|||| ||||||.. ||..|.| |..|||..... ||||....|||.|.||.|.||.| |.||.||| ||...| |..|.|||||| |. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM PPEILLE--KRYNGNEVDIWSMGVILYAMVTGQLPWTLTDG------VQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV .|||.. |.|.| .|||||.||||||||.|.||. . . . . . .| ...| .. .| |..||| .| . | .|.|...|. | |. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | MARK-B.AA | CAMK | 70-320 | 24 | 1.2e-119 | 387.35 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 70-320
Range on HMM: 1-425/425
Sequence Identity: 24% (105 aa)
TIGSGTSSKVKIGTNILTG------------KQYAIKITKPKRIKE----------------------------RKEIEREISILKR-------LKHDNI
|.|.|. .||| .....|. ...|||| . |..|. ||...|||.|.|. |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IQLHDAIYE-------DDVG-----------RICLIL---ELVSGGEL----FDYIVAR---------------GRLSEKEGRKFFRQMLCGLIYCHSNM
|.|.... .| . ...... |..||||| |||||.. ||..|.| |..|||..... ||||.
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VCHRDLKLENLLVDED-----------------GNLKISDFGYSNIIKP------------------------GNLLSTFCGSPVYAP-PEILLE-----
..|||||.||.|.|.. .|.||.||| .|...| | ...||||.| |.. ||.|.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------KRYNGNEVDIWSMGVILYAMVTGQLPWTLTDG-----------VQVEGMDRLLRGEFKYPSHVI----------------------LSDDVK
|.| | ..|.||.|||||.|..| .|. .. . | . . ..|.. .|.. . .|...|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DLINRMIVAEPVERATLDEIKTHVWV
|||..| . .| .|.|..... | |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | MARK-B.AA | AMPK | 65-320 | 49 | 6.7e-116 | 345.55 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-254/254 Sequence Identity: 49% (129 aa) YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKE---IEREISILKRLKHDNIIQLHDAI--YEDDVGRICLILELVSGGELFDYIVARGRL |..||||| ||. |||.|| ||||.. |||| ..||. . |.|||.||| ..| .|||| . | ..| | ...| ||||||||||| .||| YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTD---IFMVMEYVSGGELFDYIVKHGRL SEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMVTGQ .|.| ..|| |.. |. ||| .|. |||||.|||| |.. |.|| ||| ||. | |..|.| |||| || ||. |.|.| |||||| |||||||. | QEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY LPWTLTDGVQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV || | .. . .. . ||.. |.. ||...||||..| |..|.| ..|. | | LPF--DDENTPTLYKKIKNGEYYIPKF--LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | MARK-B.AA | NuaK | 65-320 | 42 | 4.7e-104 | 274.46 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 65-320
Range on HMM: 1-252/252
Sequence Identity: 42% (110 aa)
YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKE---IEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSE
| . || |.|| ||| .|.. ||.. ||| | ..|.. . | ||| |. | | .||. . ..| .| ...| |||||.||| ...|.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYE-VFENK-DKIVIVMEYASGGELYDYISECKSLPE
KEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMVTGQLP
.| |.|||| . ||| . .||||||||| | |...| || ||| ||. . ...| |||||| || ||| . |.| ||| ||.||.||.|| | .|
REARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMP
WTLTDGVQVEGMDR-LLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV
|| . . .|.. | . | || | .| |||. .| | ||
F---DGHDFKHLVKQISQGAYYEPCK---PSDACMLIRWMLMVNPRRRATIYDICHHWWV
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| Kinase | MARK-B.AA | S_TKc | 65-320 | 33 | 5.2e-98 | 332.84 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-231/231 Sequence Identity: 33% (90 aa) YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKEIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSG--GELFDYIVARGR---- | ....||.|. .||. .... ||...|||| | . |.|||.|||. .|.||..|.|.... .......|...| |.|||||. ||| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --LSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMV ..| . |....|..|.| ||||. ..||||| ||.|.|| ..||.||| . .. .||||.| | .||.| |.. ..|.|| |.||| |. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML TGQLPWTLTDGVQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKT-------HVWV .|. |. . . ..... |...||.|... . .| .| | |. . | |. CGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MARK-B.AA | Pkinase | 65-320 | 32 | 1.2e-93 | 322.21 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-293/293 Sequence Identity: 32% (98 aa) YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKEIE----REISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGG----ELFDYIV-- | .|..||||....|...... |||..|.|| | ...|. |... .||.|.|||.|.||..|.|. .. ..|....|.. || .||||| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW ARGRL--SEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNL----KISDFGYSNI--IKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIW ..|.. ||.| .....|.|.|| ||||. ..|||||.||.|.|..|.. ||.||| . . .. ..||||.| |..||.... .| | .||.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SMGVILYAMVTGQLPWTLT----DGVQVEGMDRLLRG---EFKYPSHVILS-----------------DDVKDLINRMIVAEPVERATLDEIKTHVWV |.|.||| |..|..|. . . | .. .| .| .| | .. ||.|.... | .| | ..|. | |. SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | MARK-B.AA | TSSK | 65-320 | 35 | 2.8e-86 | 283.17 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-289/289 Sequence Identity: 35% (103 aa) YLLGKTIGSGTSSKVKIGTNILTGKQ----------------YAIKITKPKRIKE---RKEIEREISILKR-LKHDNIIQLHDAIYEDDVGRICLILELV | .||.||.|. .||.... . . |||| |. .. .|.. |||.|.. |||.||||.. ...| |.|....|. YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFY-EMFETCQGKIYMVMEYA SGGELFDYIVAR------GRLSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGN------LLSTFCGSPVYAPPEI ..| |..|| .| |.|.|.. ||.|||| .. |||| | |||||.||.| |...|.|..||| ... ... |..||||| ||.||| EHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEI LLEKRYNGNEVDIWSMGVILYAMVTGQLPWTLTDG--VQVEGMDRLLR-GEFKYPS--HVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV |. . |... .|.||||||||.||.| .| | .. | . . ....| .. .|.. |||| .| .| .|....||. | |. LRGIPYDPKWYDVWSMGVILYIMVCGCMPF---DDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | MARK-B.AA | QIK | 65-320 | 38 | 7.3e-86 | 291.57 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 65-320
Range on HMM: 1-272/272
Sequence Identity: 38% (107 aa)
YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKER--KEIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGR----
| ...||| | ||..... | .. |||| .. | . ..||. |.|.|.| .|| | . . || . .. | |.||.|||... ||
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDM--MYIVTEYCSNGEMFDYLCKHGRKGVK
----------------LSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGNLLSTFCGSPVYAPPEILLEKRYNGNE
..|.| |. | |.. . |||. . ||||| ||.| |.. | || |||.|| |.| ||.|.|||| || ||... | |.| .
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK
VDIWSMGVILYAMVTGQLPWTLTDGVQV-EGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV
||||||||.||..|.| || ||. . . .| | | |. | .| | .|| .| | .| | | . |. | |
VDIWSMGVVLYVLVCGALPF---DGKTLQNLRQRVLSGKFRIP--FFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | MARK-B.AA | Ciliate-E2 | 65-320 | 24 | 4.1e-82 | 279.12 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-365/365 Sequence Identity: 24% (94 aa) YLLGKTIGSGTSSKVKIGTNILTGKQ-----------------------YAIKITKPKRIKERKEIEREIS-------------ILKRLKHDNIIQLHDA | . | ||.|. ..|. .......|| ||.|| |.. |.. | ..... ||..|.|.|||..... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IYEDDVGRICLILELVSGGELFDYIV------------ARGRLSEKEGRKFFRQMLC---------------GLIYCHSNM-VCHRDLKLENLLVDEDGN .| | | |..|...||.||||| . ....||| .....| | .| |.||. ..|||.|.||.|. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- LKISDFGYSNIIKPG--------------------------------NLLSTFCGSPVYAPPEILLEKRYNG--------NEVDIWSMGVILYAMVTGQL .||.|||.| .... |. |.||.| | .|||| | |.. ..||||.||||| |..|.. IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PWTLTDGVQVEGMDRLLRGEFKYP----------------SHVILSDDVKDLINR----MIVAEPVERAT-LDEIKTHVWV |. .. . .....| |. .|...||||.. |.. .| .| | ..|. | | PF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | MARK-B.AA | BRSK | 65-320 | 45 | 6.6e-82 | 278.43 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 65-320 Range on HMM: 1-254/254 Sequence Identity: 45% (118 aa) YLLGKTIGSGTSSKVKIGTNILTGKQYAIKIT-KPKRI-KE--RKEIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLS | |.|| | |. .||.|. ||| |||| | | . || .. .|||| |.| | ......| .|| |||| ||||||||| | .||| YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYD-VYENKK-YLYLILEHVSGGELFDYLVKKGRLT EKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGNLLSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMVTGQL || |||||| .| .||| .|||||| |||| ||. | || ||| . . .| | |||| || ||. | | |.|| ||||||. .| | PKEARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGAL PWTLTDGVQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEIKTHVWV | | . ... || | | . |. || || .| | .| ||. | |. PF--DDDNLRQLLEKVKRGVFHMPHFI--HPDCQDLLRGMIEVDPDKRISLKEIQKHPWY |
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| Kinase | MARK-B.AA | Ciliate-E2-Unclassified | 65-320 | 24 | 1.1e-70 | 241.1 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 65-320
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)
YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKEIER------EISILKRLK-----------------HDNIIQLHDAIYEDDVGRICLIL
| ..|.||.| .||. .. ....||.|. | ..|. .| |.. |. .....| |.... ... .. | |....
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
ELVSGGELFDYIVAR-----------------GRLSEKEGR-----KFFRQMLCGLIYCHSN-MVCHRDLKLENLLVDEDG---NLKISDFGYSNIIK--
|.. ||.|..|| | ...|.. . ..|.| |.|| |.|.. ...|||.|.||.|.|..| ..||.||| | ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
--------------PGNLLSTFCGSPVYA----PPEILLEKRYNG---NEVDIWSMGVILYAMVTGQLPWTLTDGVQ--------------VEGMDRLLR
. ....||||.| | .||.| .. |.. ..||||.|||||.|..|..| .. | . . .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
GEFKYPSHV------ILSDDVKDLIN----RMIVAEPVERATLDEIKTHVWV
.....|.. ..|. .||.|| .|.. | .| |...|. | |
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | MARK-B.AA | TyrKc | 65-318 | 24 | 4.8e-17 | 52.85 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 65-318 Range on HMM: 1-280/280 Sequence Identity: 24% (72 aa) YLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKEIEREISILKRL--KHDNIIQLHDAIYED-----DVGRICLILELVSGGELFDYIVARG |||..|.| .| || . | |.| |. |... ||..|...| .|.||..|. .. .. .. .....|....| | ||. ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR R-LSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPG--------NLLSTF--CG---SPV-YAPPEILLEKRYNGNE . |. |. .| | || | ||. . |||| | ||.|.. |||||| | |. . .. .| |. .|| . ..... . PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TK VDIWSMGVILYAMVT-GQLPWTL-----TDGVQVEGMDRLLRGEFKYPSHV-------ILSDDVKDLINRMIVAEPVERATLDEIKTHV |.|| || .. . | || |. . .| . .. .|. . . . .|.. ... . ..| .| | ||. SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV--IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | MARK-B.AA | Pkinase_Tyr | 65-207 | 29 | 6.1e-16 | 54.62 | Pfam | 1-156 (270) | Show / Hide |
Range on Protein: 65-207 Range on HMM: 1-156/270 Sequence Identity: 29% (47 aa) YLLGKTIGSGTSSKVKIGTNI----LTGKQYAIKITKPKRIKE---RKEIEREISILKRL-KHDNIIQLHDAIY-EDD-VGRICLILELVSGGELFDYIV .||..|.| .|. || |. . |.|. |.. .| |.. ||..|.| | .|.||..|. ... ... .|....|.. .| | || ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLR A----RGRLSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFG . ...|. |. .. .| .|. | .|. |||| | ||.|.. ||.||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG |
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| KA1 | MARK-B.AA | KA1 | 669-715 | 43 | 6.9e-24 | 83.31 | Pfam | 1-48 (48) | Show / Hide |
Range on Protein: 669-715 Range on HMM: 1-48/48 Sequence Identity: 43% (21 aa) RNETINFEIEVCKVN-GMDMYGIKFKRLSGDAWSYSSSCIKIVESLKL ..|...|||.||||. ...||..|||.||..| | . | ||.....| EPEVVKFEIQVCKVPGRLGLYGVDFKRVSGNQWQYKDLCTKILKEMRL |
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