Gene Apg1 (Slime mold)

Apg1

Species: Slime mold
Alias: DDB0185178, atg1, DdisK134, Apg1
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
Apg1.AA Protein None 668 None Fasta, JSON
Apg1.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of Apg1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Apg1.AA ULK 7-266 35 1.3e-126 426.91 In-house 1-324 (324) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-324/324
Sequence Identity: 35% (116 aa)

YILDKRIGWGAFA-QVYKGFSIKT---NEPFAIKVVDVCRLADKNSK-----LTENLNYEIRILKELS---HTN--IVRLYDVLNEETDPTFIYMIMECC
|.|....|.|.|. .||||. .||   |. .|.|..| . . .|...     . ..|..||.|.|.|    | |  ||.|||.... .. ..||.||| |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH-NNIYIIMEYC

EGGDFSKYIRTHKK---------LTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEH---------PILKIGDFGFAKFIDPFSLSDTFC-
.|||...|| ..||         |.|..|. |.||..||.|.|....|.|||.||||.|.... ..         ..|||.||||||..|  ..... | 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSPLYMAPEILH----RKNYT-VKADLWSVGIILYEMLVGEPAYNSGSVPDLLNQ--------------LQNKKIKLP-----SHISSDCQ
         |.||||||.||.    .|.|.  |.|.||.|.|.|||| |.. ..|    |. ..               .|..|. |      .||..|.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

NLIYSLLQIDVEKRISWEDFFNHKWL
.||. .||.| ..|||||..|||.|.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase Apg1.AA ULK 7-266 34 4.2e-122 411.95 In-house 1-329 (329) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-329/329
Sequence Identity: 34% (114 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLADKNSKLTEN-----------LNYEIRILKELS--------HTNIVRLYDVLNEETDPTFIYM
|.|....|.|.|..||||. .||. .  .... .|   ||...  .|           |. ||.|.|.|         | |||.|||.... .. . ||.
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH-NNIYI

IMECCEGGDFSKYIRTHKK----------LTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEH---------PILKIGDFGFAKFIDPF--
||| |.|||...|| ..||          |.|..|. |.||..||.|.|....|.|||.|||| |.... ..         ..|||.||||||..| .  
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNM

----SLSDT----FCGSPLYMAPEILH----RKNYT-VKADLWSVGIILYEMLVGEPAYNSGSVPDLL-----NQLQN----------KKIKLP-----S
     .. .    .||.||||||.||.    .|.|.  |.|.||.|.|.||||.|.| ...    |.      . ..|          .... |      
EQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

HISSDCQNLIYSLLQIDVEKRISWEDFFNHKWL
.||..|..||. .||.| ..|||||..|||.|.
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase Apg1.AA S_TKc 7-266 34 6.9e-97 329.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-231/231
Sequence Identity: 34% (94 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKELSHTNIVRLYDVLNEETDPTFIYMIMECCEG--GDFSKYIRTH
| . . || |||..|||.  .||.. .|||...            |..  ||.|||.  | |||.||||  .    ...||.||.|.|  ||  .||. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKR

KK------LTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFIDPFSLSDTFCGSPLYMAPEILHRKNYTV-KADLWS
..      ..|  | ..|.|....|... ...|.||||||.|.||..      .||.|||.|...      .||||.| |||||.|    |.  |.| ||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWS

VGIILYEMLVGEPAYNSGSVPDLLNQLQNKKIKLPSHISSDCQNLIYSLLQIDVEKRISWEDFFN-------HKWL
.|.||||||.|.| .    .  .....           |... ..|  .|| | |||..  . ..       | |.
CGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Apg1.AA CAMK 12-266 24 9e-92 295.95 In-house 1-425 (425) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-425/425
Sequence Identity: 24% (104 aa)

RIGWGAFAQVYKGFSIKTN------------EPFAIKVVDVCRLADKN-----------------------SKLTENLNYEIRILKELS-------HTNI
 .| |.|..|.... ..|.            . .|||..|  .| ||.                        |  .|.  ||.|.| |.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYDVLN------------EETD-----PTFIYMIM---ECCEGG----DFSKYIRTH---------------KKLTEEKALYFMKQLANGLKFLRQKQ
..||.|                ..     ....||.|   | |.||    |   ||. |               ...||. | ....|.. ..... .. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPQNLLLSDDSEHP--------------ILKIGDFGFAKFIDP------------------------FSLSDTFCGSPLYMA-PEILHRKN---
|||||||| |.||.|....                .|| |||||...||                          .  ||||.| ||| ||.| .|    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YTVKADLWSVGIILYEMLVGEPAYNSG-------------SVPDLLNQLQNKKIK-LPSH---------------ISSD--------CQ
           |. |.| ||.|.||| ||.|.| ...              . ..|. . .. |    |..               || .        |.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLIYSLLQIDVEKRISWEDFFNHKWL
.|| ..|| | |||.. |.  ||.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Apg1.AA Pkinase 7-266 31 1.1e-85 295.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKELSHTNIVRLYDVLNEETDPTFIYMIMECCEGG----DFSKYIR
| . ..|| |.|..|||.  ..|.. .|.|......  ..  .   .|  ||.|.|.|.| |||||||.  .   .. |||.||.||||    | . ||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYIS

--THKKL--TEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLS-DDSEHPILKIGDFGFAKF--IDPFSLSDTFCGSPLYMAPEILH-RKNYTVKAD
   |...  .|. .  .|.|.. ||... .. |.||||||.|.|.. ..   ...||.|||.||.  . . |  .||||.| |||||..  .. |. |.|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

LWSVGIILYEMLVGEPAYNSG------SVPDLLNQLQNKKIKLPSHIS---------------------SDCQNLIYSLLQIDVEKRISWEDFFNHKWL
 ||.|.|||||| |.| . .       .   ....   .... ..  .                     ..|. .|...|. | .||...|. ..|.|.
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Apg1.AA Ciliate-E2 7-266 27 5e-85 288.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-365/365
Sequence Identity: 27% (104 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPF------------------AIKVVDVCRLADKNSKLTENLNYEIR-------------ILKELSHTNIVRLYDV
|.. | || |.|..|||.  .|... |                  .|| . . ..  .. . ... ....|             ||..|.| ||...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LNEETDPTFIYMIMECCEGGDFSKYIR------------THKKLTEEKALYFMKQLAN---------------GLKFLRQKQ-IVHRDLKPQNLLLSDDS
  .|.| . ||..|| |.|||  .||.              |..||....|.|||...               .|..| .|  |.|||.||.|.|.    
F-QEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

EHPILKIGDFGFAKFIDPF--------------------------------SLSDTFCGSPLYMAPEILHRKN---------YTVKADLWSVGIILYEML
    .|| |||..|..|..                                 . .|.||.| ||||||| .|.         |. |.|.||.|.||||||
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

VGEPAYNSGSVPDLLNQLQNKKIKLP------------------SHISSDCQNLIYS----LLQIDVEKRIS-WEDFFNHKWL
 |.| .        ..| ...||..|                   ..| .|..||      .|| | ||||. ||. .||.|.
FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Apg1.AA CAMKL 7-266 31 6.6e-85 270.88 In-house 1-297 (297) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-297/297
Sequence Identity: 31% (94 aa)

YILDKRIGWGAFAQVYKGFSIKT-NEPFAIKVVD--VCRLADKNSKLTEN--------LNYEIRILKELS---HTNIVRLYDVL-NEET---DPTFIYMI
|.. | .| |.|..|  .  |.| .|  |||..|   ... ....|   .        .  ||.|.| |.   | ||..||.|. ..|.     . ||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MECCEGGD--FSKYIRTH----KKLTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFIDP-----FSLSDTFCGSPL
|| |.||.     ||. |    ....|. |  . .|.  ..... .. |||||.|| |.||...  .  .|| ||||. ...|       . .|||||| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YMAPEILHR--KNYT-VKADLWSVGIILYEMLVGEPAYNSGSVP---------DLLNQLQNKKIKLPSHISSDCQNLIYSLLQIDVEKRISWEDFFNHKW
||||||. .  | |   |.| || |.||| |..|.   .  ...          . .  . ...  ..|.| ||..|| ..|| . |||.. ..  ||.|
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

L
.
M
Kinase Apg1.AA CAMK1 7-266 33 5.1e-75 217.5 In-house 1-276 (276) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-276/276
Sequence Identity: 33% (95 aa)

YILDKRIGWGAFAQVYKGFSIKT---NEPFAIKVVD-VCRLADKNS-KLTENLNYEIRILK---ELSHTNIVRLYDVLNEETDPTFIYMIMECCEGGD-F
|...|.|| |||..||..  ..|   ....|||. |    .. |.  |  |.|  || |.|   ...| ||. .|..     .....|..|| . ||. |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYE---SDNHFYLVMELVTGGELF

SKYIRTHKKLTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHPILK--IGDFGFAKFIDPFS-LSDTFCGSPLYMAPEILHR---KNYTV
 . |   .. ||..|   |||..  .... .| ||||||||.|||..| .|. ..|  | ||| .|..|. . |  | ||.| |.|||.| .   | |  
DR-IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDK

KADLWSVGIILYEMLVGEPAYNSGS-VPDLLNQLQNKKIKLPSH----ISSD-CQNLIYSLLQIDVEKRISWEDFFNHKWL
. |.||.|.|.| .|.| |  .. .  . |. .  . ..  ||     ||.    ..|  .|  | .||.. |.. ||.|.
ACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase Apg1.AA MARK 7-266 36 5.4e-74 241.3 In-house 1-262 (262) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-262/262
Sequence Identity: 36% (97 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLAD-KNSKLTENLNYEIRILKELSHTNIVRLYDVLNEETDPTF-IYMIMECCEGGDFSKYIRTH
| . | || |..|.|... ...|.. .|||...  .| | .. |   |.  ||.|.| |.| ||..|..|   . ...  ||.|||...||.   ||. |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMK---NVMREIEIMKKLDHPNIIKLFHVIE-QDTEQHQIYLIMEYASGGELYDYIKAH

--KKLTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFIDPFSLSDTFCGSPLYMAPEILHRKNYT-VKADLWSVGII
   .|.|| |  . .|.  ..... .| |||||.||.|.|. ..  |   || ||||.  | | .. .||||.| ||||||. .| |.  |.| || |..
PNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNH-NIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVV

LYEMLVGEPAYNSGS--VPDLLNQLQNKKIKLPSHISSDCQNLIYSLLQIDVEKRISWEDFFNHKWL
|| |..|   .   .    .|  . .. | . |.|.| .|.||| .||... |.|.. |.  .|.|.
LYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase Apg1.AA Ciliate-E2-Unclassified 7-266 25 5e-73 248.91 In-house 1-352 (352) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLADKNSKLTE-NLNYEIRILKELSHTNIVR-----------------LYDVLNEETDPTFIYMI
|.. | || |.|..|||   .|... .|.|   . .  ........ ... |. ....... ...|                 ..  . ...|   ||..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MECCEGGDFSKYIRTHKK-----------------LTEEKAL-----YFMKQLANGLKFLRQKQ-IVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFID-
|| ||||| ..||.  ||                 .||..|.     ....|. .||..| .|. |.|||.||.|.|.... .   .|| |||..|... 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PFSLSDTFCGSPLYM----APEILHRKNYT----VKADLWSVGIILYEMLVGEPAYNSGSVPD----------------LLNQLQ
               .. ...||||.| ||    |||.| ..||      |.| ||.|.|||||| |.. ... .  .                |... .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NKKIKLPS--------HISSDCQNLIY----SLLQIDVEKRISWEDFFNHKWL
.|.|. |.        |.|  ....|     ..|. . .|||..|. .|| |.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase Apg1.AA STE 7-266 22 7.9e-70 238.29 In-house 1-359 (359) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-359/359
Sequence Identity: 22% (82 aa)

YILDKRIGWGAFAQVYKGFSI------KTNEP---------FAIKVVDVCR------------LADKNSKLTENLNYEIRILKELS--HTNIVRLYDVLN
. . ..|| ||| .|||.  .      ||.|          .|||......            | .||..  ...  ||.|.|...  | |||. |.   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EETDP----TFIYMIMECCEGGDFSKYIR-THKKLT-------------EEKALYFMKQLANG-LKFLRQKQIVHRDLKPQNLLLSDDSEHPILKIGDFG
 | ..    . ....|| ..|| ... |. .....              |.   |. .|.  | |..| ...|.|||.||.| ||         |. |||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDFG

FAKFIDP-----------------FSLSDTFCGSPLYMAPEILHR------KNYTVKADLWSVGIILYEMLVGEPAYNSGSVP-DLLNQLQN--------
... ...                  . ..||.|.| .||||.. .      | |..|.| ||.|. . ||. |.| .  .. .  ... ..|        
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

-------KKIKLPSHIS-------------------SDCQNLIYSLLQIDVEKRISWEDFFN--HKWL
       .  .||.|.|                   ..... |   ||.| .|| . ..  .  |...
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase Apg1.AA RAD53 7-203 30 1.7e-65 193.87 In-house 1-232 (305) Show / Hide 
Range on Protein: 7-203
Range on HMM: 1-232/305
Sequence Identity: 30% (72 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLA---DKNSKLTENLNYEIRILKELSHTNIVRLYDVLNE-ETDPTFIYMIMECCEGGDFSKYIR
|...| .| |.|..|....  || . .||| .|  ...    ...| ..... |..||| |.| .|.|.||.  . ...    ||..|  .||...  | 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKY---YYMVLELMTGGELFNKIV

THKK----LTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHP---------------ILKIGDFGFAKFIDPFSLSDTFCGSPLYMAPEI
 .|.    ..| .. |. .|. ...| |  . |.|||||| | |.....|                 ..|| ||| .||..  |.  |.||.|.| |||.
SNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEV

LHRK---------------NYTVKADLWSVGIILY
.  |                || | |.|| | |||
ITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILY
Kinase Apg1.AA Pkinase_Tyr 7-206 32 2e-29 100.29 Pfam 1-208 (270) Show / Hide 
Range on Protein: 7-206
Range on HMM: 1-208/270
Sequence Identity: 32% (70 aa)

YILDKRIGWGAFAQVYKGFSI----KTNEPFAIKVVDVCRLADKNSKL--TENLNYEIRILKEL-SHTNIVRLYDVLNEETDPTFIYMIMECCEGGDFSK
 ...| .| ||| .||||       .|. | |.|..      .  ..    | .  |..|.|.| .| |||||| |  .. .|  ||..|| ...||  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YIRTH----KKLTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFI--DPFS-LSDTFCGSPL-YMAPEILHRKNYTV
| |.|    ..|| .  | .  | |.|. .| .|...||||   | |...     . ||.||| |. |  |     . . .  |   |||| .. . .|.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTT

KADLWSVGIILYEML
| | || |. ..|..
KSDVWSFGVLMWEIF
Kinase Apg1.AA TyrKc 7-266 24 2e-20 75.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

YILDKRIGWGAFAQVYKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKEL--SHTNIVRLYDVLNEET------DPTFIYMIMECCEGGDFS
  |.| .| ||| .||||  .   .. |.|..  .          | .  |.||...|  .| |||||| |  ..       .|  ....|| ...||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP--LMIVMEYMPHGDLK

KYIRTHKK-LTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFIDPF------SLSDTF----CG---SPL-YMAPEI
.|.| |.. |. .. |.|. | |.|  .| .|...||||   | |....    . ||.||| ...|.        .   .     .|    |.  |||| 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LHRKNYTVKADLWSVGIILYEMLVGEPAYNSG------SVPDLLNQLQNK-KIKLPSH--------ISSDCQNLIYSLLQIDVEKRISWEDFFNHKWL
.  . .| | | || |. ..|..       .|      |  ........    . | .         ...  ... .  . | |.| . ..   |. .
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase Apg1.AA RAD53 233-266 35 5.3e-10 25.45 In-house 272-305 (305) Show / Hide 
Range on Protein: 233-266
Range on HMM: 272-305/305
Sequence Identity: 35% (12 aa)

SHISSDCQNLIYSLLQIDVEKRISWEDFFNHKWL
. ||.  ..|| ..|..|.|||.. ..  || |.
DRISEEAKDLIKWMLCVDPEKRYTIDEALNHPWM