Gene Bub1 (Slime mold)

Bub1

Species: Slime mold
Alias: DdisK074, Bub1, DDB0231500
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: BUB

Sequence

Name Sequence Type Origin Length Description Download
Bub1.AA Protein None 1306 None Fasta, JSON
Bub1.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of Bub1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Mad3_BUB1_I Bub1.AA Mad3_BUB1_I 40-164 48 1.8e-68 234.72 SMART 1-133 (133) Show / Hide 
Range on Protein: 40-164
Range on HMM: 1-133/133
Sequence Identity: 48% (64 aa)

LEKEKQKFEIII--NEYQGEDPIDNWLKYIKWVQQSYPGG--NMKEQLIVLLERCTRLFLSTEKYKNDPRYLRIWITYADMC----RDPIEVFSFLEVQR
||...|.||  |  ..|.|.||.| |. ||||..|.|| |  .....|..||||||| |.. |.||||||||.|||.|.|||     .|.|.|.......
LEQQRQEFEQEIQDDSYEGDDPLDVWYRYIKWTEQNYPQGQQTKQSGLQTLLERCTRYFWDDERYKNDPRYLKIWIWYMDMCYNYFDEPREIFQYMYRHG

IGFYLSLLYEARAIVYENKGNYEQADKSFKQGI
||  ..|.||. | .|||.|||..||. ...||
IGTQCALFYEEWAQWYENMGNYQKADEIYQLGI
Mad3_BUB1_I Bub1.AA Mad3_BUB1_I 40-164 39 6.8e-48 168.98 Pfam 1-134 (134) Show / Hide 
Range on Protein: 40-164
Range on HMM: 1-134/134
Sequence Identity: 39% (53 aa)

LEKEKQKFEIIINEYQ---GEDPIDNWLKYIKWVQQSYPG--GNMKEQLIVLLERCTRLFLSTEKYKNDPRYLRIWITYADMCR----DPIEVFSFLEVQ
|....| ||  | .|.   | || . |. ||||....||   |. ...|  |||||.. |.. |.||||||||.||. |...|     .|...|.... |
LQQQRQQFEEEIQNYECEEGDDPLQPWYRYIKWMEEAYPQGGGTKQSGLPTLLERCVKYFWHDERYKNDPRYLKIWLWYMNYCNNNFDEPRDIFQYMYNQ

RIGFYLSLLYEARAIVYENKGNYEQADKSFKQGI
 ||  ..|.||. |  .|..|....||. |. ||
GIGTKCALFYEEWAQYLESMGKWQKADEVFQLGI
Kinase Bub1.AA BUB 1003-1271 42 3.6e-155 521.8 In-house 39-311 (311) Show / Hide 
Range on Protein: 1003-1271
Range on HMM: 39-311/311
Sequence Identity: 42% (117 aa)

WLSCKVQDPPSIWEFYIGNQIHQRLQERSLTISNSKFPTIHSLYYYTDKSIMLMDHTIDQGTLDDVVSSTN------GVPMEEPLAMFHCIELLKMIEDL
|..||||.||..|||||..|.|.||.|||.|.....|..|.|..||.|||.|.|...||.|||.||.....      ...|.|...||.|...|||.|.|
WVACKVQKPPNPWEFYICDQMHERLKERSETMMHCCFMHICSCHYYQDKSCMWMEYHIDYGTLLDVINHMKEKAQVNNKVMHEYWVMFFCCQMLKMVEHL

HLVGIIHGNICANNLHFLFGQTSDWPDWTAGECKGAWKSKGFTLTDFSRSIDTTIYSQDARYQSPIELLPIGTPLEWLKINQSSTTNVGWSYNLDYLGIC
| ..||||.|...|.........||..|....|..|||.||..|.||.||||.|......|.....|....  |.|.....||||||..|.|..||.||.
HRCEIIHGDIKPDNFMLMNRIHDDWDCWHKMSCGEAWKNKGLKLIDFGRSIDMTLFPDGQRFKFNCETQQD--PFECWEMQQSSTTNCPWTYQVDYFGIA

KVMFHILTCGKEELKLSLSQQTGKLEIINQSIIQKDSFSELDTLWLPFLTTLLNHNGENGNQQTTTTTYILKQQR
..|...|.......|.....|..|||.......||||||||||.|..|....||||||....||......|.||.
ATMHCMLFGKYMQVKQKWDGQYWKLEQNFRRYWQKDSFSELDTMWNKFFHRMLNHNGEIPDCQTLPMWHELRQQF
Kinase Bub1.AA Worm8 1089-1111 52 0.000114 9.35 In-house 108-130 (261) Show / Hide 
Range on Protein: 1089-1111
Range on HMM: 108-130/261
Sequence Identity: 52% (12 aa)

LLKMIEDLHLVGIIHGNICANNL
| |   | | .||.|| | |.||
LVKILQDIHSFGIVHGDIKADNL