Gene DDB0220652 (Slime mold)

DDB0220652

Species: Slime mold
Alias: DDB0220652, DdisK122
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0220652.AA Protein None 637 None Fasta, JSON
DDB0220652.kin_dom Protein Kinase Domain None 348 None Fasta, JSON

Protein domain

Protein domains of DDB0220652.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0220652.AA PEK 236-611 25 4.5e-148 498.22 In-house 1-637 (655) Show / Hide 
Range on Protein: 236-611
Range on HMM: 1-637/655
Sequence Identity: 25% (166 aa)

FNDVRVLGKGGF-GIVFQCCNIFDQMEYAVKRIKVN------------------QKIPTKELMEVRAMARLNHPNIVRYYGSWIEEEIITN---------
|.....|||||| |.|....|..|...||.||||.|                  .|. .|.|.||...|||||||||||. .|||...  .         
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIVRYHNAWIEKPEEKWQQQQDEMWQ

-------------------------------------------------------------NSIDHYGENDNNLFENIDSFPS-----------------
                                                             |..... |........ .|||.                 
LDSSTDWPNGKHKSKDYNFHPFEKEWDDEEAQESNVMSECEDREQKGKKKCWSESNSHSSKNNYEESMEWSCSEHSDSSSFPNIENQFSINFGTENENES

-------SSYSSVSAAASSSSLVSNSSNSYSNNKATYISNSSSSSSSSSS--------------------------------------------------
       |.|.|.|......| .|||..|...||....|..|.||.||.|                                                  
HISYWSSSVYMSSSWDNPFDSSFSNSCDSTNFNKDEDHSFFSCSSYSSCSTDCDDSKDSSPFNWDGGCDNWEQYEYSDQDDEHEQNDCQSKQCDSKNQSH

------------------CSYSIGNGNLSISECTNDDNNNYNQLKQKK-------FSLYIQMELCKYSTLRNLIN-----------------EINNIKSI
                  ||..||. . |..|..|..|||.|..||..       . ||||||.| ..|||..|.                 ...|.. |
KKCMEMTWIQDQEDNKNNCSHHIGSSSQSQEEMENNTNNNKNKFKQMHNTKQYQCHYLYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNY-I

TS---IQSTSSIANPIGTN---ILISLDIKQCREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPF----GIKIGDFGLATTIESLTVDSN-------
..   .|||.|. |. ...   .. ..| .||..|.|||| .|.||||||..|||..| |.|.... .    ..|||||||||..|.|.. |.       
MNQCCFQSTWSM-NM-RQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFLDCDGQHHQMQVKIGDFGLATNHEMLSQ-SQKNYNQQD

-------NNNNNNINNNNNNNKKV---------------------------GGLGTYLYSSNEQEQGD-----NYNQKTDLYSVGVIFFEMLSQFKTTM-
       .|.|....|.|..|..                            ||.||.||.|.||. |      .||.|.|.|| |.|||||. .|.||| 
QSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMM

ERSTTLSKLKK---SLSVLKTNPNLKQKYPNDTDFIDHLIQ
||..|| .|..    .     .... .|||.  ||| ....
ERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLS
Kinase DDB0220652.AA PEK-Unclassified 373-584 35 6.9e-128 431.17 In-house 429-796 (835) Show / Hide 
Range on Protein: 373-584
Range on HMM: 429-796/835
Sequence Identity: 35% (132 aa)

CSYSIGNGNLSISECTNDDNNNYNQLKQKK-----------------------------------------FSLYIQMELCKYSTLRNLIN---------
||..|||.|..|..|.|..|||||||.|..                                         |..|||||||.|.|.|..||         
CSHDIGNNNQIIQQCQNNNNNNYNQLQQNQQQNQANSISNTKSYERRKNKSMDYLTIDQKQREFQLDKYDEFIFYIQMELCHYTTARYIINRNKKLFSQQ

-------------EINNIKSITS----IQSTSSIANPIGTN------------------------------------ILISLDIKQCREITRQILVALKY
             .|||.|.|..    ||||.|..|...||                                    |||.....|||||||||..||..
QFNQNLSIKNSCANINNNKNIKNQNLCIQSTQSMFNMNETNSFSGQQNSINNNLNQNNLMHPTLTYSNSCNCSDPFDILIFEYKQQCREITRQIIKALYH

IHSQG-FVHRDITPDNVFVCQSPFGIKIGDFGLATTIESLTVDSN--------------NNNNNNINNNNNNNKKVGG----------------------
||.|. .|||||.|.|.||||.|..||||||||...||.|..|..              ||||||.|.||||||.||.                      
IHHQCKMVHRDIKPHNIFVCQNPMQIKIGDFGLVKKIEKLINDNQKIQYNDHQLYGKKLNNNNNNMNQNNNNNKFVGASTSPSETNSGYHDKLPFYLPKE

-----LGTYLYSSNEQE-----------QGDNYNQKTDLYSVGVIFFEMLSQFKTTMERSTTLSKLKK
     .|||.|||||||           |.|.||..||.||||.|||.|..|..|||||..|....||
EITSTCGTYTYSSNEQESQKKVRIKAHFQADFYNHRTDIYSVGIIFFQMFHQMNTTMERVKTIQNCKK
Kinase DDB0220652.AA GCN2 236-586 23 2.3e-57 196.89 In-house 1-467 (511) Show / Hide 
Range on Protein: 236-586
Range on HMM: 1-467/511
Sequence Identity: 23% (114 aa)

FNDVRVLGKGGFGIVFQ-CCNIFDQMEYAVKRIKVN---QKIPTK--ELMEVRAMARLNHPNIVRYYGSWIE--EEIITNNSIDHYGENDNNLFENIDSF
|  ...||||||| |     |  |   ||.|....|   .|.|.|   . ||   .||.|...|||| .|||  .|. .... .   .|.|  ...    
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRLHHQHVVRYYQAWIEKCDEPMVTDTNNDDDTNNNYHSDDESEC

PSSSYSSVSAAASSSS---LVSNSSNSYS--NNKATYISNSSSSSSSS----------------------------------------------------
.|..|.. ... .|..   . .... |.|  .|  .. .|.   |...                                                    
FSGQYEMPKSVNQSEEMCNKEESMEWSMSNERNNSNWHDNGNFFSEWDNPFDQPFGPKCAFRMGQKRTFDLTDDHYSYCHSDCEFDDDVFDIDWDIESNN

-----SSC--SYSIGNGNLSISECTNDDN------------------------------NNYNQLKQKKFS----------LYIQMELCKYSTLRNLINE
     |..  .   ...| |    ..|.                               |  . .. .|..          |||||| |  .|||..| .
VRDMESDDNEWEQEQQNNQSFQPKQEDHQNQYYDQEDLNNAESEDQNKKKSQQQDKMCQNQHKNKVHYKCMNCKKPKEVHYLYIQMEYCEGKTLRQYIDN

--INNIKSITSIQSTSSIANPIGTNILISLDIKQCREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPFGIKIGDFGLATT--IES------------
   .. .                          . ....|||| .|.|||||| .|||. | |.|. .. . .|||||||||.   ||            
HGWCMDHD-------------------------ELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFLDCCGN-VKIGDFGLATNNKMESQINRKQQKQQQQ

-------LTVDSNNNNNNNINNNNNNNKKV-------GGLGTYLYSSNEQEQGDNYNQKTDLYSV-GVIFFEMLSQ-FKTTMERSTTLSKLKKSL
       .  .. ....| . .  .....        |. ||..| . ||.    |||| |.||  |.|||||. . | | |||. .| .|. |.
ASSHWAIQNEICQDDQFNQQQSQFSQWDQQDEQVHHTGKVGTPFYMCPEQQ-KSHYNQKVDMYSLGGIIFFEMWYPPFCTQMERVQILKQLR-SC
Kinase DDB0220652.AA PEK-Unclassified 236-307 61 2.3e-55 190.25 In-house 393-472 (835) Show / Hide 
Range on Protein: 236-307
Range on HMM: 393-472/835
Sequence Identity: 61% (49 aa)

FNDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVN--------QKIPTKELMEVRAMARLNHPNIVRYYGSWIEEEIITN
||.|...|.|||.||.|||..|||||||||.|.||        ||...||.||||.||..|||||.|||.||||.||..|
FNQVQKIGQGGFAIVYQCCHKFDQMEYAVKQIHVNIKDIKEDLQKHYEKEIMEVRYMAQVNHPNIIRYYHSWIEVEIKKN
Kinase DDB0220652.AA CAMK 241-567 14 5.7e-36 112.87 In-house 1-329 (425) Show / Hide 
Range on Protein: 241-567
Range on HMM: 1-329/425
Sequence Identity: 14% (63 aa)

VLGKGGFGIVFQCCNIFDQ------------MEYAVKRIKVNQKIP---------------------------TKE--LMEVRAMAR-------LNHPNI
.||.|.||.|. |... ..             ..|.| |. ..                              ...  . |.. | .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYYGSWIEEEIITNNSIDHYGENDNNLFENIDSFPSSSYSSVSAAASSSSLVSNSSNSYSNNKATYISNSSSSSSSSSSCSYSIGNGNLSISECTNDDN
.. |  .  .. .  |                                                                                    
IKLYEVYEDPHYFK-N-T----------------------------------------------------------------------------------

NNYNQLKQKKF-----------SLYIQM---ELCKYS----TLRNLINEINN-----IKSITSIQSTSSIANPIGTNIL------ISLDIKQCREITRQI
       .  .            .|. |   |.|        | . | |  .     .                             .. ...| . |||
-------ND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFD--------------------QFDIVERGRFTEREARRYFRQI

LVALKYIHSQGFVHRDITPDNVFVCQSP----------------FGIKIGDFGLATTIESLTVDSNNNNNNNINNNNNN--------NKKVGGLGTYLYS
. |..|.||.. ||||. |.|. ....                 . ||| |||.|. ...   . ... ... .   .|         |     ||  | 
CSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYM

S-NEQEQG--------------DNYNQKTDLYSVGVIFFEMLS
.  |  .|              . |..|.|  |.||| . ||.
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLC
Kinase DDB0220652.AA Ciliate-E2-Unclassified 236-568 17 1.3e-33 113.95 In-house 1-266 (352) Show / Hide 
Range on Protein: 236-568
Range on HMM: 1-266/352
Sequence Identity: 17% (65 aa)

FNDVRVLGKGGFGIVFQCCNIFDQ----MEYAVKRIKVNQKIPTKE---LMEVRAMARLNHPNIVRYYGSWIEEEIITNNSIDHYGENDNNLFENIDSFP
.. ....|.||||.|..| .. ..    |.|. | ....||.  ..   ..|  .| .... ...|                                  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQR-K--------------------------------

SSSYSSVSAAASSSSLVSNSSNSYSNNKATYISNSSSSSSSSSSCSYSIGNGNLSISECTNDDN---------------NNYNQLKQKKFSLYIQMELCK
                                                            .  |                ..   .|.|. .|| ||.|.
------------------------------------------------------------Y--NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCE

YSTLRNLINEINN---IKSITSIQSTSSIANPIGT---NILIS---LDIKQCR-----EITRQILVALKYIHSQG-FVHRDITPDNVFVCQSP--FGIKI
. .|.. |.. ..   .                |    . . .   .. .|..      ...|||..|.|.|... ..||||.|.|... ..   . |||
GGDLWQYIKKRKKQKQK----------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI

GDFGLATTIESL-TVDSNNN-NNNNINNNNNNNKKVGGLGTYL--YSSNEQEQGDNYN----QKTDLYSVGVIFFEMLSQ
 |||..  ...    | .|. .. .|. ... . ..| .. |.  | . |  || ||.     | | .|.|||..||| .
IDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPN-YMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG
Kinase DDB0220652.AA Ciliate-E2 400-567 21 5e-32 107.23 In-house 104-291 (365) Show / Hide 
Range on Protein: 400-567
Range on HMM: 104-291/365
Sequence Identity: 21% (47 aa)

QKKFSLYIQMELCKYSTLRNLINEI-----NNIKSITSIQSTSSIANPIGTNILISLDIKQCREITRQILV---------------ALKYIHSQG-FVHR
... ..|. ||.|.. .|. .|..      ..|.                     ....|....|..|||                ||.|.||..  .||
KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE----------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

DITPDNVFVCQSPFGIKIGDFGLATTIESLTVDSNNNNNNNINNNNNNNKKVGG----------------------LGTYLYSSNEQEQGDN--------
|| |.|...      ||| ||||.. .      ...|.|. . .. .....  .                      .||. | . |  .| .        
DIKPENILF------IKIIDFGLSKKY------DDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

-YNQKTDLYSVGVIFFEMLS
 |. | |..|.|||..|||.
GYDYKCDIWSLGVILYEMLF
Kinase DDB0220652.AA PEK 236-310 28 1.9e-26 84.37 In-house 351-463 (758) Show / Hide 
Range on Protein: 236-310
Range on HMM: 351-463/758
Sequence Identity: 28% (32 aa)

FNDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVNQ-----KIPTKELM-----EVRAMARLNHPNIVRYYGSWIEEE----------------------
|  . .||.||||.||.  |. |  .||.||| .          ...       |||. | |.|.|||||. .| |..                      
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAMLDHHNIVRYFNAWLETPELLPPNNKMRSTSFSTVNGKQI

------IITNNSI
      .| ||..
DSNNDNDIYNNHF
Kinase DDB0220652.AA Pkinase 449-567 30 1.3e-23 84.53 Pfam 104-207 (293) Show / Hide 
Range on Protein: 449-567
Range on HMM: 104-207/293
Sequence Identity: 30% (38 aa)

ISLDIKQCREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPFGI----KIGDFGLATTIESLTVDSNNNNNNNINNNNNNNKKVGGLGTYLYSSNEQE
. .. ..|. . .||| .|.|.||.|..|||. |.|...  .   |    ||.|||||  ..                . ||    .  ||. | . |  
Y-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD----------------Y-NNS-MTTFCGTPWYMAPEVI

Q-GDNYNQKTDLYSVGVIFFEMLS
. |  | .| | .|.|.|..|||.
RGGQYYGPKVDMWSCGCILYEMLC
Kinase DDB0220652.AA STE-Unique 459-576 29 4.5e-21 71.16 In-house 408-557 (616) Show / Hide 
Range on Protein: 459-576
Range on HMM: 408-557/616
Sequence Identity: 29% (44 aa)

ITRQILVALKYIHSQG--FVHRDITPDNVFVCQSP----FGIKIGDFGLATTIESL-----TVDSNNNNNNNINNN----------------NNNNKKVG
.|.||| .| |.|||.   .|||. |.|.|  |.       .||.|||.||.            .| |  .|||||                 ||    .
YTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKY

GLGTYLYSSNEQEQGD-----NYNQKTDLYSVGVIFFEMLSQFKTTMERS
. ||  | . |   .       |. | | .| | ..|.|.... . ..|.
CCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRY
Kinase DDB0220652.AA STE 236-422 12 1.4e-20 69.42 In-house 1-129 (359) Show / Hide 
Range on Protein: 236-422
Range on HMM: 1-129/359
Sequence Identity: 12% (28 aa)

FNDVRVLGKGGFGIVFQCCNI------FDQME---------YAVKRIKVNQK----------------IPTKE--LMEVRAMARLN--HPNIVRYYGSWI
. .....|||.|| |....|.        . .         .|.|.......                .  ..  |.|.. | ..|  |||||.|||. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EEEIITNNSIDHYGENDNNLFENIDSFPSSSYSSVSAAASSSSLVSNSSNSYSNNKATYISNSSSSSSSSSSCSYSIGNGNLSISECTNDDNNNYNQLKQ
 |                                                                                                ..
KEGHN---------------------------------------------------------------------------------------------HK

KKFSLYIQMELCKYSTLRNLIN
 . .|.| ||.. . .|. .|.
NDDELWICMEYMDGGSLDDIIK
Kinase DDB0220652.AA PEK-Unclassified 308-372 30 2.2e-19 63.75 In-house 256-359 (835) Show / Hide 
Range on Protein: 308-372
Range on HMM: 256-359/835
Sequence Identity: 30% (32 aa)

NSIDHYGENDNNLFENIDSFPS---------------------------------------SSYSSVSAAASSSSLVSNSSNSYSNNKATYISNSSSSSS
|.|.||..||||..||.|.||.                                       |.||||..|........|.|.||.||...|.||..|.|.
NNINHYNINDNNDMENQDPFPNPNVASKQKPSQIKIFNNNSNGNSAEIPNTKKSSKDIKKLSEYSSVMHANNNEESQENDSQSYNNNQSDYQSNFESYSE

SSSS
.|.|
KSKS
Kinase DDB0220652.AA Pkinase 236-301 36 4.8e-18 64.88 Pfam 1-71 (293) Show / Hide 
Range on Protein: 236-301
Range on HMM: 1-71/293
Sequence Identity: 36% (26 aa)

FNDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVNQKIPTKE-----LMEVRAMARLNHPNIVRYYGSWIE
.  .|..|.|.|| |..|... .. ..|||.||.  . . |.     |.|.. |.|||||||||.|... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED
Kinase DDB0220652.AA HRI 236-303 38 1.6e-17 57.68 In-house 1-71 (613) Show / Hide 
Range on Protein: 236-303
Range on HMM: 1-71/613
Sequence Identity: 38% (27 aa)

FNDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVNQKIPT---KELMEVRAMARLNHPNIVRYYGSWIEEE
| .  ..||||.| |.   .  |   ||.|.||. ..  .   | . ||. .| |.|.|||||  .|||..
FEQKEIIGKGGYGRVYKVRHKLDKQHYAIKKIKIKKRTKCSCMKMQREVKVLACLQHHNIVRYHQAWIEHV
Kinase DDB0220652.AA STE 454-566 27 1.6e-17 58.53 In-house 151-262 (359) Show / Hide 
Range on Protein: 454-566
Range on HMM: 151-262/359
Sequence Identity: 27% (35 aa)

KQCREITRQILVA-LKYIHSQGFVHRDITPDNVFVCQSPFGIKIGDFGLATTIESLTVDSNNNNNNNINNNN------NNNKKVGGLGTYLYSSNEQEQG
.| . |.|||| . |.|.||.. .|||| |.|...      .|. |||... ...   .. . .|| | ...      ..|  ||      . . |  |.
SQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVCGQLTDSMANI-Q-SNN-I-IDCIETMQQKRNTFVGTP----WMAPEVIQQ

------DNYNQKTDLYSVGVIFFEML
      . |. | | .|.|    ||.
NGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase DDB0220652.AA S_TKc 236-632 14 3.8e-17 64.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 236-632
Range on HMM: 1-231/231
Sequence Identity: 14% (61 aa)

FNDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVNQKIPTKELMEVRAMARLNHPNIVRYYGSWIEEEIITNNSIDHYGENDNNLFENIDSFPSSSYSSV
.  .|..|||.|| |..| .. .. ..|.|.||                                                                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

SAAASSSSLVSNSSNSYSNNKATYISNSSSSSSSSSSCSYSIGNGNLSISECTNDDNNNYNQLKQKKFSLYIQMELCKYS-------TLRNLINEINNIK
                                                                       |. |.   .       .|   . . ... 
---------------------------------------------------------------------EHIRREIQILKKHHPNIVKLYDVFQD-DHLY

SITSIQST--SSIANPIGTNIL----ISLDIKQCREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPFGIKIGDFGLATTIESLTVDSNNNNNNNINN
 ..   ..   .    |  .        ..  ..| ...||. ||.|.||.|..|||. |.|.....    |||.|||||. .                 
MVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----------------

NNNNNKKVGGLGTYLYSSNEQEQGDNYNQ-KTDLYSVGVIFFEMLSQFKTTMERSTTLSKLKKSLSVLKTNPNLKQKYPNDTDFIDHLIQ-SFATRPFSN
           ||  | . |      |.  | | .|.|.|..|||.  ..  .   .. .. | .             |   |||... |   . ||   
-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-

QIST---DYDNFPPK
.. .   |  . |  
EALQDEWDIKCHPWF
Kinase DDB0220652.AA STE-Unique 237-381 26 4.8e-14 45.74 In-house 251-450 (616) Show / Hide 
Range on Protein: 237-381
Range on HMM: 251-450/616
Sequence Identity: 26% (54 aa)

NDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVNQKIP-------TKELMEVRAMARLNHPNIVRYYGSWIEE-----------------EIITNNSIDH
|.   .|.|.|| |. | |. |   .|.| |...|. .        . . |. .|..|.|.|||.|||.|...                 .. |  | | 
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGGCDSFQSLEEGNEDLSGDLETDASEDW

YGENDNNLFENIDSFPSSSYSSVSAAAS-----------------------------------SSSLVSNSSNSYSNNKATYISNSSSSSSSSSSCSYSI
.     |    |      ||| .| . |                                   |||  | ||   ||||.  | | | | |   | | | 
FMQSSINSRSIIS---RDSYSGLSTSNSNVGGVNNTAGGGDSVSNANSNKSMIVGNSNKKLTLSSSNTSSSSSLLSNNKSK-ILNTSKSTSTNTSTSTST

GNGN
 | |
SNTN
Kinase DDB0220652.AA PEK 531-584 41 5.3e-14 41.95 In-house 664-717 (758) Show / Hide 
Range on Protein: 531-584
Range on HMM: 664-717/758
Sequence Identity: 41% (23 aa)

GGLGTYLYSSNEQEQGDNYNQKTDLYSVGVIFFEMLSQ-FKTTMERSTTLSKLKK
. .||  |.. || .. .|| |.| || | ||||..   | | ||| .|. .|..
SVFGTGTYTNPEQKKT-WYNHKVDIYSLGLIFFELIHPGFSTQMERIRTMCDLRN
Kinase DDB0220652.AA PEK 456-507 31 1e-12 37.57 In-house 444-520 (758) Show / Hide 
Range on Protein: 456-507
Range on HMM: 444-520/758
Sequence Identity: 31% (24 aa)

CREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPF-----------------------GIKIGDFGLAT--TIES
.  .  ||. .. |||| |. |||  | |.|  .                           ||||||||.|  || .
MLHWFHQICEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQIIKIGDFGLVTDHTIVT
Kinase DDB0220652.AA Ciliate-E2 236-303 19 2.9e-12 38.39 In-house 1-107 (365) Show / Hide 
Range on Protein: 236-303
Range on HMM: 1-107/365
Sequence Identity: 19% (21 aa)

FNDVRVLGKGGFGIVFQCCN-----------------------IFDQMEYAVKRIKVNQKIPT-KELMEVR-------------AMARLNHPNIVRYYGS
.. ....|.|.||.|..|..                        .....||.|..| ||.. . .|. . |              . .||||||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WI--EEE
..   ..
FQEKDDN
Kinase DDB0220652.AA TyrKc 236-626 13 1.6e-11 -36.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 236-626
Range on HMM: 1-280/280
Sequence Identity: 13% (57 aa)

FNDVRVLGKGGFGIVFQCCNIFDQMEYAVKRIKVNQKIPTKELM-EVRAMARL--NHPNIVRYYGSWIEE--------------EIITNNSIDHY-GEND
    ..|| | ||.|...  .   .. ||| .| .     ...| | | | .|  .|||||| ||  ...              |   . . ..|  .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NNLFENIDSFPSSSYSSVSAAASSSSLVSNSSNSYSNNKATYISNSSSSSSSSSSCSYSIGNGNLSISECTNDDNNNYNQLKQKKFSLYIQMELCKYSTL
..                                                                                                  
PK--------------------------------------------------------------------------------------------------

RNLINEINNIKSITSIQSTSSIANPIGTNILISLDIKQCREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPFGIKIGDFGLATTIESL-TVDSNNNN
                                 |  |.  ..  ||     |.||....|||.   |. |      .||.||||.  |..  .       
---------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQG-----

NNNINNNNNNNKKV----GGL--GTYLYSSNEQEQGDNYNQKTDLYSVGVIFFEMLSQFKTTMERS----TTLSKLKKSLSVLKTNPNLKQ--------K
       .   ...    ||     .   . |  .   .. |.| .| ||  .|...  ..  .       . . . . .   .  |  .          
------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCC

YPNDTDFIDHLIQS-FATRPFSNQISTDY
 .   . .    .   . ||  ..|  . 
PDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0220652.AA HRI 532-579 47 1.9e-11 35.79 In-house 520-567 (613) Show / Hide 
Range on Protein: 532-579
Range on HMM: 520-567/613
Sequence Identity: 47% (23 aa)

GLGTYLYSSNEQEQGDNYNQKTDLYSVGVIFFEMLSQFKTTMERSTTL
. || .| | ||  | .|  | |.|| ||| ||.   | | ||| . |
RVGTCTYASPEQLDGSQYDNKSDMYSMGVILFELFQPFGTEMERAEVL
Kinase DDB0220652.AA HRI 405-504 33 3.2e-11 34.98 In-house 394-486 (613) Show / Hide 
Range on Protein: 405-504
Range on HMM: 394-486/613
Sequence Identity: 33% (35 aa)

LYIQMELCKYSTLRNLINEINNIKSITSIQSTSSIANPIGTNILISLDIKQCREITRQILVALKYIHSQGFVHRDITPDNVFVCQSPF---GIKIGDFGL
|.|||.||  ..|.  | | |  .|   .  |   ..|           |    |  ||.  . |||  . ||||..| |.|          .|||||||
LHIQMQLCE-LSLWDWISERNK-RSREYVDET---ECP-----YVMANEKVIQKIFQQIVEGMFYIHNMFIVHRDVKPRNIFLHDPDQGHPQVKIGDFGL

ATT
| .
ACE
Kinase DDB0220652.AA Pkinase_Tyr 466-507 35 5e-06 20.94 Pfam 123-163 (270) Show / Hide 
Range on Protein: 466-507
Range on HMM: 123-163/270
Sequence Identity: 35% (15 aa)

ALKYIHSQGFVHRDITPDNVFVCQSPFGIKIGDFGLATTIES
.. | .|....|||.   |. |  .   .||.||||| .|..
GMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLARDIYN
Kinase DDB0220652.AA Pkinase_Tyr 236-297 27 0.000155 15.99 Pfam 1-71 (270) Show / Hide 
Range on Protein: 236-297
Range on HMM: 1-71/270
Sequence Identity: 27% (20 aa)

FNDVRVLGKGGFGIVFQCCNI----FDQMEYAVKRIKVNQKIPTKE------LMEVRAMARL-NHPNIVRYYG
    ..||.| || |...        .... ||| .  ...   ..      . |.. |  | .||||||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG
Kinase DDB0220652.AA STE-Unique 405-423 36 0.125137 0.87 In-house 369-387 (616) Show / Hide 
Range on Protein: 405-423
Range on HMM: 369-387/616
Sequence Identity: 36% (7 aa)

LYIQMELCKYSTLRNLINE
..|.||.|  .||. .|..
VWIFMEYCEHGTLQQIIKR