Gene DDB0231182 (Slime mold)
DDB0231182
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB0231182.AA | Protein | None | 1221 | None | Fasta, JSON |
| DDB0231182.kin_dom | Protein Kinase Domain | None | 330 | None | Fasta, JSON |
Protein domains of DDB0231182.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | DDB0231182.AA | Haspin | 189-452 | 15 | 2e-63 | 217.04 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 189-452 Range on HMM: 1-264/264 Sequence Identity: 15% (43 aa) NMQKTG-GRNGSVFFVNNNNNSNNNNNNNNNNNNNNNNNNNN------NNNNNNNNDNSNNKNNFKNNNTSYTHNSNKNNNENKNTFAIKQQLVSTPKNK |..|.| |..|.||.|..|. ............... .......||...|............|.....|..|........|.......| NCKKIGEGCYGEVFSVTWNG-------KEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKK LSQTYREKVILEHLNILIESNKACNFPKLINWYKAAPTSNLSNVN-NNNSNNNNNNSNNNITNSRYGSNYEDIYDDNYYDEVDDYDSGKEEEESTKTITK | ..........|.......... .....|.|........|.|.. ..|..|...........|.| ...|. ...|... .......|........... LNKMWDHYCYTHHSENDRPDFFK-KNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMD TITTTTASIKPNIQYMHLILEYANMGTLKEYGKDNNFEFTISQMKSLLFQVIYSLAISQKEFEFVHNDLHFG ..|....|................... |.| ...|.|....|.....|.|..........|.|||...... GKTIKIKSHGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK |
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| S_TKc | DDB0231182.AA | S_TKc | 187-627 | 9 | 4.6e-07 | -73.37 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 187-627
Range on HMM: 1-231/231
Sequence Identity: 9% (46 aa)
NNNMQKTG-GRNGSVFFVNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNDNSNNKNNFKNNNTSYTHNSNKNNNENKNTFAIKQQLVSTPKNKLSQT
..| | | |.|. . ... . .|||.
YEILRKIGKGAFGKVYKCRHKK--------------------------------------------------------TGRIVAIKIIK-----------
YREKVILEHLNILIESNKACNFPKLINWYKAAPTSNLSNVNNNNSNNNNNNSNNNITNSRYGSNYEDIYDDNYYDEVDDYDSGKEEEESTKTITKTITTT
..| . |
------------------------------------------------------------------------------------------EHIRREIQIL
TASIKPNI---------QYMHLILEYANM--GTLKEYGKDNNFE-----FTISQMKSLLFQVIYSLAISQKEFEFVHNDLHFGNVLLTSFPVDKKYIVYQ
||| .......||.. |.|..| |... . |. . .... |.. |. . ..| || |.||..
KK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-----------
DKLDNGEFNNWIVGGDFIVKISDFGLSRIKLPSN----------EIIYNQRNDRSKEFCF-YSDLYSFSSLLNKIKIKESPSSSSTTSTSTSQVLIKSDS
.||.||||.|. . |.. . . .| .|. .| . | . . . ...
-----------------HIKICDFGLARQL--TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----
DSSSSASSSSSSSSSSSSSSSSSLPKSKNKSNRSKDNQSKLDPEKRLLTKLKKSMKD--LPPYKLLD-------HPFF
.. | .. |. . . . ..| ||.|
----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | DDB0231182.AA | RAD53 | 485-498 | 57 | 0.000101 | 9.42 | In-house | 163-176 (305) | Show / Hide |
Range on Protein: 485-498 Range on HMM: 163-176/305 Sequence Identity: 57% (8 aa) DFIVKISDFGLSRI .|..||.|||||.. SFLIKITDFGLSKF |
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| Kinase | DDB0231182.AA | Frk | 479-512 | 47 | 0.000282 | 10.33 | In-house | 128-161 (260) | Show / Hide |
Range on Protein: 479-512 Range on HMM: 128-161/260 Sequence Identity: 47% (16 aa) NWIVGGDFIVKISDFGLSRIKLPSNEIIYNQRND | .|| . |.|| |||| |. . || || | . NVLVGEHNICKIADFGLARVLMKDNEDIYESRHG |
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| Kinase | DDB0231182.AA | Trk | 479-497 | 63 | 0.000298 | 10.22 | In-house | 147-165 (275) | Show / Hide |
Range on Protein: 479-497 Range on HMM: 147-165/275 Sequence Identity: 63% (12 aa) NWIVGGDFIVKISDFGLSR | ||.. ||||.|||.|| NCLVGQNLIVKIGDFGMSR |
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| Kinase | DDB0231182.AA | TK-Sp1 | 479-496 | 55 | 0.000303 | 10.93 | In-house | 144-161 (270) | Show / Hide |
Range on Protein: 479-496 Range on HMM: 144-161/270 Sequence Identity: 55% (10 aa) NWIVGGDFIVKISDFGLS | || . ..|||||||. NVLVGKGLMCKISDFGLA |
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| Kinase | DDB0231182.AA | FGFR | 479-497 | 52 | 0.000652 | 9.16 | In-house | 166-184 (293) | Show / Hide |
Range on Protein: 479-497 Range on HMM: 166-184/293 Sequence Identity: 52% (10 aa) NWIVGGDFIVKISDFGLSR | |. |.. ||.||||.| NVLVTDDYVMKICDFGLAR |
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| Kinase | DDB0231182.AA | SFK-Src | 479-498 | 45 | 0.000736 | 6.66 | In-house | 126-145 (259) | Show / Hide |
Range on Protein: 479-498 Range on HMM: 126-145/259 Sequence Identity: 45% (9 aa) NWIVGGDFIVKISDFGLSRI | || ..|. |||.||. NVLVGDNNVCKVGDFGMSRV |
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