Gene PLK (Slime mold)

PLK

Species: Slime mold
Alias: DdPLK, PLK, DDB0216332, DdisK123
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
PLK.AA Protein None 978 None Fasta, JSON
PLK.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of PLK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PLK.AA PLK-Unclassified 163-416 65 3.3e-196 658.12 In-house 1-264 (264) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-264/264
Sequence Identity: 65% (172 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQKTVMDIHKKR-------
|..|.|||||||||||.....||..||||||||||.|.|.|||.||.||||||.||.|.||||||||||..||||||||.|...|.|...|.|       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

KYLMEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFI-DNMRIKLGDFGLSTKVEH-GERKKTICGTPNYIAPEILDNSN-GHSYEVDVWSIGIILYT
|.|.|||.|.|.||...|..|||.|.||||||||||.|. |||..|..||||.||.|. ||.|||||||||||||||||... |||||||.||.|.||||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

LLIGKPPFETSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF
||||||||||.|||.||..||.||||||....||...|.||..|||..|.|||...||..|.|.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase PLK.AA PLK 163-416 60 1e-189 622.8 In-house 1-258 (258) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-258/258
Sequence Identity: 60% (157 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQKTVMDIHKKR-KYLMEY
|..|.||||||||||| ||...|...||.|..|||..||...| |.|.||.||..|.|.|||||.|.||..|||||.||.|.... |..||.| |.|.|.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

ETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFI-DNMRIKLGDFGLSTKVEH-GERKKTICGTPNYIAPEILDNSN-GHSYEVDVWSIGIILYTLLIGKP
|..||.||......|||...||||||||||||. |||..|.|||||.|..|. ||||||.||||||||||.||... |||||||.||.|.|.||||||||
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF
||||.|||.||.|||.|.||||....||...|.||...||..|..||...|||.|.||
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase PLK.AA PLK1 163-416 55 7e-130 429.25 In-house 1-253 (253) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-253/253
Sequence Identity: 55% (141 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQKTVMDIHKKRKYLMEYE
|..|.||||||||.|| .....|. ..|.|..||| | |  .| |.  ||.|| .|.|..|||| | || ..||||.||||... .|..||.|| . |.|
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

TKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFI-DNMRIKLGDFGLSTKVEHG-ERKKTICGTPNYIAPEILDNSNGHSYEVDVWSIGIILYTLLIGKPPF
..||.||.. ..||||||.||||||||||||. |....|.||||| ||.|.  |||||.||||||||||.| |  |||.|||.|||| |.|.||.|.|||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVL-NKKGHSFEVDIWSIGCIMYILLFGQPPF

ETSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF
||. .| ||.|||.|.|. |.  .||.  ..||...|.|.|..||.  |.|. .||
ETKCLKETYSRIKKNEYRIPS--HISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase PLK.AA PLK2 163-416 48 2.9e-126 408.72 In-house 1-257 (257) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-257/257
Sequence Identity: 48% (127 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQ----KTVMDIHKKRKYL
|..|  |||||||.|| ||  .|. .||.||.|.|   | . | |   || .|. | | .||.| | ||  .|.|||||.|      |    . | |. |
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

MEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFI-DNMRIKLGDFGLSTKVE-HGERKKTICGTPNYIAPEILDNSNGHSYEVDVWSIGIILYTLLIG
 | |  ||  |..  . |||   ||||||||||.|| ||| .| |||||  ..|  .....|.||||||||||.| | .||| | |.|. | | ||.|.|
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVL-NRQGHSCESDIWALGCIMYTMLCG

KPPFETSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF
 |||||.. | ||..|..| | .|     |   ..|| ..| | || || | .|..||||
RPPFETANLKETYRCIRHNHYHMPTH--LSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase PLK.AA AGC 163-416 20 2.7e-102 264.7 In-house 1-395 (395) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-395/395
Sequence Identity: 20% (81 aa)

YRQGEFLGKGGFAKCYLMTEV------ETNRIYAAKIIPKST-LQKTR--ARSKLKSE------------IKIHSSLS----------HENIVK-FEHCF
..    .|||.| |.||  ..       |...|| |.. |..  ....     . ..|             .| . ..          | .|||   ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENEEN--VYILLELCN----------Q-KTVMDIHK--KRKYLMEYETKYYVYQ-------VIMAVQYLHN-NNIIHRD-LKLGNLFIDN-MRIKLGDFG
.....  .|...|...             . . ...  |.... | ....|  .       ...|..|||. ..||||| ||. |. .|.   ||| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTKVEHGE---------------------------------------------------RKKTICG--TPNYIAPEILDNSNGHSYEVDVWS--IGIIL
|....  ..                                                   | .|.||  ||.|.|||||     .....| ||   |...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YTLLIGKPPFETS----------DVKHTYQRIK------QNQYSFP--------DEPIISHYGKSLIISILNPVPEQRPN----------LTQILEHDFF
| .|.|.|||             . . ..|.|.      ...  ||        ... .|   |.||   |.. ||.|.             .| .| .|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PLK.AA S_TKc 163-416 32 6.4e-98 332.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQ--KTVMDIHKKRKY---
|. .. .|||.|.|.|. ....|.||.| |||.           ....||.|...  |.||||.  .|.. ...|. .|.|..   ...|. |||..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LMEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFIDNMRIKLGDFGLSTKVEHGERKKTICGTPNYIAPEILDNSNGHSY-EVDVWSIGIILYTL
   . | ....|.||.. |..|.|...|||||||  |...|. .||..||||....      .|.||||.|.|||.|    |... ..|.||.|.||| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

LIGKPPFETSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILE-------HDFF
| |.|||.  ... ....|.            |. .|..|  .|.  ||.||   ..|.       | .|
LCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PLK.AA CAMK 168-416 21 6.1e-93 299.77 In-house 1-425 (425) Show / Hide 
Range on Protein: 168-416
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

FLGKGGFAKCYLMTEVETN------------RIYAAKIIPKSTLQK-------------------------TRARSKLKSEIKIHSSLS-------HENI
 ||.|.|.| .| .. .|.            . .|.|||.|. |..                          . | ....||.|...|.       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFEHCFEN-------------------EENVYILL---ELCNQK----TVMDIHKKR---------------KYLMEYETKYYVYQVIMAVQYLHNNNI
.|. . .|.                   ....|. .   |.|        . |  ...               ... | |...|. |.. ||.|.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLGNLFIDNM------------------RIKLGDFGLSTKVEH------------------------GERKKTICGTPNYIA-PEILDN------
.|||||. |. .|.                    ||. |||...|...                        |.  || |||| |.| ||.|        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------SNGHSYEVDVWSIGIILYTLLIGKPPFETS-------------DVKHTYQRIKQNQYSFPDEPI--------------ISHY--------GKS
         ......|.||.|.|||..| |.|||. .             . . ....|.. .|.||....              ||           |.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIISILNPVPEQRPNLTQILEHDFF
|| ..|.. ||.|....|.|.| ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PLK.AA Pkinase 163-416 31 1e-92 319.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLK-SEIKIHSSLSHENIVKFEHCFENEENVYILLELCNQ--KTVMDIH-----KK
|. |. .|.|.|...|. ... |..|.| |||.|..  .   ..... |||.|. .|.|.|||.. ..||.. ..|. .|.|.   . ||| .     ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

RKYL--MEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFID-NMRI----KLGDFGLSTK--VEHGERKKTICGTPNYIAPEILDNSNGHSYEVDVWS
.. .   | | | |.||.. ...|.|...|||||||. |..|| |. |    |..||||. .    ...  .|.||||.|.|||..  .......||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGIILYTLLIGKPPFETS------DVKHTYQRIKQNQYSFPDEPIIS-------------------HYGKSLIISILNPVPEQRPNLTQILEHDFF
.|.||| .| |.|||  .      | .. ..||.. ...|. .  .|                     .|..| ..|.. |..||. .|||.|..|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PLK.AA CAMKL 163-416 30 3.6e-83 265.23 In-house 1-297 (297) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-297/297
Sequence Identity: 30% (92 aa)

YRQGEFLGKGGFAKCYLMTE-VETNRIYAAKIIPKSTLQKTRARSK------------LKSEIKIHSSLS---HENIVKFEHCFENEEN------VYILL
|| |. ||||.|.|  | |    |.. .| ||| |. ...    .|            .. ||.|...|.   |.||.|. ...|..|.      .|. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCNQKT--VMDIHKKRKY----LMEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFID-NM--RIKLGDFGLSTKVE-H----GERKKTICGTPNYI
|.|       .|  .|...    . | |.. |  |.. ||.|.|...|.|||.|. |. .| |.   ||. |||.|.. . .    |.  || ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILDN--SNGHSYEVDVWSIGIILYTLLIGKPPFETS--------DVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF
||||.       . ..||.||.|.|||... |. ||.          ..   | .|..  | .|  . .|   ..|| ..|.. ||.||.. ||..| ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase PLK.AA MARK 163-416 33 3.9e-75 245.08 In-house 1-262 (262) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-262/262
Sequence Identity: 33% (89 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIVKFEHCFE--NEEN-VYILLELCNQKTVMDIHKKR--KY
|. .  .|.|..|| .| . . |.| .| ||..|  |..  .......||.|...|.|.||.|. | .|  .|.. .|. .|..  . ..|  |..   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LMEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFIDNMR---IKLGDFGLSTKVEHGERKKTICGTPNYIAPEILDNSNGHSYEVDVWSIGIILYTLL
| | |.. .  |.. ||.|.|..||.|||.|. |. ||  .   ||. |||.|.... |.. .| |||| | ||||.       ..||.|| |..||...
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

IGKPPFE--TSDVKHTYQRIKQNQYSFPDEPIISHYGKSLIISILNPVPEQRPNLTQILEHDFF
 |. ||.  | | |  |..|   .|..|.   .|.  ..|| ..|.. ||.|| ...|..| ..
CGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase PLK.AA Ciliate-E2 163-416 24 1.4e-74 254.08 In-house 1-365 (365) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIY------------------AAKIIPKSTLQKT--RARSKLKSEIK-------------IHSSLSHENIVKFEHC
|   . .|.|.|.. |...  .... .                  ..||. . ...|   .. .. .....             | ..|.| ||.|.  |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--NEENVYILLELCNQKTVMD-------------------IHKKRKYLMEYETK-------YYVYQVIMAVQYLHNNN-IIHRDLKLGNLFIDNMRIK
|.  ...|.|. .|.|.... .|                    .|..||.|.. ..       .|. ..| |..|||..| |||||.|. |...    ||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

LGDFGLSTKVEHGERKKT--------------------------------ICGTPNYIAPEILDN--------SNGHSYEVDVWSIGIILYTLLIGKPPF
. |||||.|.   . ..|                                |||||.| ||||| .        ..|..|..|.||.|.||| .| |||||
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF

ETSDVKHTYQRIKQNQYSFP----------------DEPIISHYGKSLIIS----ILNPVPEQRPN-LTQILEHDFF
        .| |||....||                .   .|  .| ||      .|.  ||.|..   |||.| .|
--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase PLK.AA Ciliate-E2-Unclassified 163-416 27 3.3e-69 236.24 In-house 1-352 (352) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIP-------KSTLQKTRARSKLKSEIKIH----------------SSLSHENIVKFEHCFENEENVYIL
|. .. .|.|||.| |.. . ... .|| |..        |. ..|    .  . |....                ... |..|||...||....|.|| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LELCNQKTVMDIHKKR-----------------KYLMEYETK-----YYVYQVIMAVQYLHNNN-IIHRDLKLGNLFIDNM----RIKLGDFGLST----
.|.|.... ....|||                 | . |...|     .| .|.. . .||| .| |||||.|. |...||     .||. |||.|     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----KVEHG---------ERKKTICGTPNYI----APEILDN-SNGHS--YEVDVWSIGIILYTLLIGKPPFE-TSDVKH---------------TYQRI
    . . .         .. .|.||||||.    |||.|..  ..||  |..|.|| |.||| .| |..||. ... .|                || |
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KQNQYSFPDEP------IISHYGKSLII----SILNPVPEQRPNLTQILEHDFF
||....|| .|      ..|  .| .|     ..|.  |..|... |||.| .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase PLK.AA TyrKc 163-416 21 3e-14 7.72 SMART 1-280 (280) Show / Hide 
Range on Protein: 163-416
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSL--SHENIVKFEHCFENE-------ENVYILLELCNQ---KTVMD
 . |. || | | . |. |     .  | | . ...      |  . .|..| ..|  .|.|||..  .   .       | ..|..|..     |    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

IHKKRKYLMEYETKYYVYQVIMAVQYLHNNNIIHRDLKLGNLFIDNMR-IKLGDFGLSTKVEHG----ERKKTIC-----GTP-----NYIAPEILDNSN
 |...  |   .  .. .|.    .||| .|.|||||   |  ... . .| .||||| .....    |.|...      |.         ||| . | .
KHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

GHSYEVDVWSIGIILY---TLLIGKPPFET-----SDVKHTYQRIKQNQYSFPDEP-------IISHYGKSLIISILNPVPEQRPNLTQILEHDFF
  . . |||| |. ..   |.  |..| .       . .. ....||  .  . .        . .    ... .  .  ||.||. ..|  |..|
KFTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PLK.AA Pkinase_Tyr 266-314 32 4.5e-05 17.81 Pfam 116-165 (270) Show / Hide 
Range on Protein: 266-314
Range on HMM: 116-165/270
Sequence Identity: 32% (16 aa)

YVYQVIMAVQYLHNNNIIHRDLKLGNLFID-NMRIKLGDFGLSTKVEHGE
. .|. .. .||...|.|||||   |  .. |. .| .||||.  ... .
MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD
Kinase PLK.AA Pkinase_Tyr 203-243 27 0.001197 12.98 Pfam 43-89 (270) Show / Hide 
Range on Protein: 203-243
Range on HMM: 43-89/270
Sequence Identity: 27% (13 aa)

RA--RSKLKSEIKIHSSL-SHENIVKFEHCFE-NEEN--VYILLELC
..  | .. .|.|| ..| .|.|||..  .    .|   .|| .|..
EQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYM
POLO_box PLK.AA POLO_box 703-772 30 9.1e-18 69.23 Pfam 1-74 (74) Show / Hide 
Range on Protein: 703-772
Range on HMM: 1-74/74
Sequence Identity: 30% (24 aa)

FTNKYGLAYVLSNSYVGAY-FNDSTKIVTLIESE-IAYYMEHAKGTDGDGRRVLNVTQQ------HPHDTQKKVTLIK
. .|||. | |||  |. . |||.|||. . ...    |..| . .  ...|.   ...      .|.| |||.|..|
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDH-D-P--NWQRQTYPLSTILEHGCYPEDLQKKLTYLK
POLO_box PLK.AA POLO_box 831-896 24 2.6e-07 30.58 Pfam 1-74 (74) Show / Hide 
Range on Protein: 831-896
Range on HMM: 1-74/74
Sequence Identity: 24% (18 aa)

IKFDNGIAFRLSDKTIQVN-YLDKSRIIVSSKDM--VTFVP--YRGQIITGTLNYFKNG---DKKISEKIKYIY
 . . || ..||..|.||| . |...||.... .  ||.      .| .| .|.         . . .|..|. 
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK