Gene SAMK-D (Slime mold)

SAMK-D

Species: Slime mold
Alias: SAMK-D, DdisK127, smkD, DDB0229404
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: SAMK

Sequence

Name Sequence Type Origin Length Description Download
SAMK-D.AA Protein None 553 None Fasta, JSON
SAMK-D.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of SAMK-D.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Sam7 SAMK-D.AA sam7 24-85 22 0.000211 13.61 In-house 1-70 (70) Show / Hide 
Range on Protein: 24-85
Range on HMM: 1-70/70
Sequence Identity: 22% (16 aa)

WDNETVCKWLLNNIKTIQKVSIEIFQANEI-----IGKDLEFLTDKILLKMGV---GIRDILNFKFEYQI
|. |.|| ||      . .  .. |....|      |..|  .|.. |..||.   | |. .  ...  .
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_2 SAMK-D.AA SAM_2 21-71 26 0.000886 15.82 Pfam 1-54 (71) Show / Hide 
Range on Protein: 21-71
Range on HMM: 1-54/71
Sequence Identity: 26% (15 aa)

YKKWDNETVCKWLLNNIKTIQKVSIEIFQANEIIG-KDL-EFLTDKIL--L-KMGV
.. |..|.|| ||  .|.   .   ..| ...|.| ..| . .|   |    .||.
VHYWTFEDVCEWLR-SIGM-CCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGI
Kinase SAMK-D.AA SAMK 134-392 55 2.8e-201 654.11 In-house 1-295 (295) Show / Hide 
Range on Protein: 134-392
Range on HMM: 1-295/295
Sequence Identity: 55% (164 aa)

YQYIETISKNKFCEIEKYKKSQTKVNEYIIIKKIIKNSTLNEEKLINEIDTIYLLDHPNLIKIIGYCKDKNYFYIGMKYYETFKFKQSNIS----KFGKN
||||||||..|||..||||||..|.||.||||.|.|||.||||..||||...|..||||.|||||||||.||.||.||||.....|..|.|    .....
YQYIETISRGKFCIVEKYKKSKKKTNEFIIIKRINKNSNLNEEMIINEINMLYSIDHPNIIKIIGYCKDENYYYIAMKYYPKGSIKKNNKSIKSKNQSPY

FEQVIRKISFKILSAIDYLHSLEPPIIHGNINAKNILLDNENNEPILIDFGLSYKSIDLLTN--------------------------------QKTQFI
.|..||||||||||||||||||.|||||..||..||||||||.||||||||||||.||..||                                .|||..
SEMNIRKISFKILSAIDYLHSLNPPIIHRDINCDNILLDNENDEPILIDFGLSYKEIDDNTNNDDDNYDNHNHNHNHNHNHNHDNDNDNDTNVKFKTQCC

SPCFITPEYFYKKTKNKISKEADIFSFGSTISNMIKGGTDFKEDEEGFEELKRTFAGVLTSRDKVSFDYRSLFTEINKDEPCFRPSSKELLKSFW
|||...|||...|.|...|||.||.|||.||..||.||||||||.|.....|..........|......|.||.||||.|.||||.||.|||.||
SPCWASPEYIHNKEKQHFSKECDIYSFGCTIFEMIVGGTDFKEDWEPWYKKKNHQIHLPKIPDYMTLECRILFNEINKYEQCFRPDSKQLLKFFW
Kinase SAMK-D.AA Ciliate-E2-Unclassified 134-334 21 2e-22 74.65 In-house 1-266 (352) Show / Hide 
Range on Protein: 134-334
Range on HMM: 1-266/352
Sequence Identity: 21% (58 aa)

YQYIETISKNKFCEIEKYKKSQTK-------VNEYIIIKKIIKNST---LNEEKLINEID-------------TIYLLDHPNLIKIIGYCKDKNYFYIGM
|  |..| .  |... | .....|        . ..|.|. ....    .||.| .|..                . ..||...| . . .||...|| |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

KYYETFKFKQ-SNISKF--------------GKNF-EQVIR-----KISFKILSAIDYLHSLEPPIIHGNINAKNILLDNENN--EPILIDFGLSYKSID
 | |  . .|  ...|.              .| | || ..     ..   ||....|||.    ||| .|   |||.||...  .. .||||.|.|...
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

L---------------LTNQKTQFISPCFI----TPEYFYKKTKNKIS-KEADIFSFGSTISNMIKG
                  ...|.  .|...     ||.. ..  .. . ...||.|.|  .  |. |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG
Kinase SAMK-D.AA Ciliate-E2 134-334 20 1.8e-21 70.49 In-house 1-292 (365) Show / Hide 
Range on Protein: 134-334
Range on HMM: 1-292/365
Sequence Identity: 20% (60 aa)

YQYIETISKNKFCEIEKYKKSQTKVNE-----------------YIIIKKIIKNSTLNEEKLINEIDTIY-----------------LLDHPNLIKIIGY
|  |. | .  |  . | |. ... ..                 . | .. .|.   |. . |. .. |.                 .|.|||.||.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CK--DKNYFYIGMKYYETFKFKQ---SNISKFGKNFE-------QVIRKISFKILS---------------AIDYLHSLEPPIIHGNINAKNILLDNENN
 .  |.|..|. | |..    ..   .|  |.....|       . |..|. .||.               |. ||||  . ||| .|   |||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF-----

EPILIDFGLSYKSID------------LLTNQK----TQFI----------------SPCFITPEYFYKKT------KNKISKEADIFSFGSTISNMIKG
 . .|||||| |  |            .... |    ...                 .| .  || . .|       ..  ....||.|.| ..  |. |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG
Kinase SAMK-D.AA TKL 140-325 18 1.1e-20 71.21 In-house 1-276 (364) Show / Hide 
Range on Protein: 140-325
Range on HMM: 1-276/364
Sequence Identity: 18% (53 aa)

ISKNKFCEIEKYKKSQTKV------NEYIIIKKIIKNS----TLNE-----------------------EKLINEIDTIYLLDHPNLIKIIGYCKDKNY-
| .  |.|. | |  .. .      .. . .||. ...    |.|.                       .....||  .  |.|||.....|||.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FYIGMKYYE--T-FKFKQSNISKFGKNFEQVIRKISFKILSAIDYLHSLE------PPIIHGNINAKNILLDNENNE-----------
            ..| | |..  . . . .           ... ...  | ....|||| .      ||||| ... ||||.|. ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PILIDFGLSY------KSIDLLTN-------------QKTQFISPCFITPEYFYKKTK-------------NKISKEADIFSFG
  . . |||||       .. |  |.               ||  .|..  || . ....              . |. .|..|||
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFG
Kinase SAMK-D.AA STE 134-334 21 1.3e-16 55.3 In-house 1-264 (359) Show / Hide 
Range on Protein: 134-334
Range on HMM: 1-264/359
Sequence Identity: 21% (59 aa)

YQYIETISKNKFCEIEKYKKS------QTKVN-------EYIIIKKIIKNSTL-----------------NEEKLINEIDTIYLLD--HPNLIKIIGYCK
.. || | |  | .  | ..       .|. .       |.. ||.. ...                   .......||..   ..  ||| .| .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DK-------NYFYIGMKYYE--TFKFKQSNISKFGKNF-----------EQVIRKISFKILSA-IDYLHSLEPPIIHGNINAKNILLDNENNEPILIDFG
..       .. .| | | .  ..     .  . ||..           |..|..| . || .  .||||.   |||  | . ||||        |.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL------VKLCDFG

LSYKSIDLL-------------TNQ-KT-QFI-SPCFITPEYFYK-KTK--NKISKEADIFSFGSTISNMIKG
.. . .| .             |.| |.  |. .| .  ||   . ...  .. .  .|| |.| ||  |. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATG
Kinase SAMK-D.AA CAMK 166-325 18 1.7e-15 45.74 In-house 37-321 (425) Show / Hide 
Range on Protein: 166-325
Range on HMM: 37-321/425
Sequence Identity: 18% (52 aa)

KIIKNSTLN-----------------------------EEKLINEIDTIYL-------LDHPNLIKIIGYCKD-------------------KNYFYIGM
|||. . |                              .... .||.   .       |||||.||.. .  |                   ....|. |
KIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVM

------KYYETFKFKQSNISKFGKN--------------F-EQVIRKISFKILSAIDYLHSLEPPIIHGNINAKNILLDNEN----------------NE
         | |    . | . |..              | |.  |..   |.||..|.||.   |.|  .   |||||. |                | 
EIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNN

PILIDFGLS--YKSIDLLT---------------------NQKTQFISPCFIT-PEYFYKKT-----------KNKISKEADIFSFG
  .||||..  ... . ..                       ||.. .|...  || . .|.           |  .....|. | |
IKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCG
Kinase SAMK-D.AA S_TKc 134-393 21 1.2e-14 37.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 134-393
Range on HMM: 1-231/231
Sequence Identity: 21% (60 aa)

YQYIETISKNKFCEIEKYKKSQTKVNEYIIIKKIIKNSTLNEEKLINEIDTIYLLDHPNLIKIIGYCKDKNYFYIGMKYYET-----FKFKQSNISK---
|. ...| |  | .  | ..     ...  ||.|        |....||.     .|||..|..... | ...|. | | ..     |.. ... ..   
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FGKNFEQVIRKISFKILSAIDYLHSLEPPIIHGNINAKNILLDNENNEPILIDFGLSYKSIDLLTNQKTQFISPCFITPEYFYKKTKNKISK-EADIF
  |    | ..|..   |..|..|.||.   |||  .   |||||.   .  ..||||. .        .|.  .| .. || .      . .| ..|. 
FPFP---E-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL------GYGKCKCDWW

SFGSTISNMIKGGTDFKEDEEGFEELKRTFAGVLTSRDKVSFDYRSLFTEINKDEPCFRPSSKELLK-------SFWF
|.| ..  |. | . |        .....|  ..      | . ...   . . .|  ||.  |.|.         ||
SCGCILYEMLCGYPPFP-------QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SAMK-D.AA Ciliate-E1 140-322 20 4.8e-11 32.64 In-house 1-202 (202) Show / Hide 
Range on Protein: 140-322
Range on HMM: 1-202/202
Sequence Identity: 20% (42 aa)

ISKNKFCEIEKY--KKSQTKVNEYIIIKKIIKNSTLNEEKLINEIDTIYLLD-HPNLIKIIGYCK-DKNYFY-IGMKYYETFKFKQSN----------IS
|... |  . |   ....... . .||. ... .  .....|.|.. |  .  . ..|.|| | | |.||.. | . ...   ... .          ..
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ

KFGKNFE-QVIRKISFKILSAIDYLHSLEPPIIHGNINAKNILLDNENNEPILIDFGLSY--KSIDLLTNQKTQFISPCFITPEYF----YKKTKNKISK
.  ..|  | . .| | .. .. .||..   |||..|. .||| .|. .. .. |||.|   |. .. . |......    ...|.    . . ..||..
QNQNQFTFQQKMQIIFQLIDGLIELHQYN--IIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINY

EADIF
. ||.
KSDIY
Kinase SAMK-D.AA Pkinase 166-400 20 7.8e-11 39.39 Pfam 30-264 (293) Show / Hide 
Range on Protein: 166-400
Range on HMM: 30-264/293
Sequence Identity: 20% (52 aa)

KIIKNSTLNEEKLIN-----EIDTIYLLDHPNLIKIIGYCKDKNYFYIGMKYYETF----KFKQSNIS-KFGKNF---EQVIRKISFKILSAIDYLHSLE
|||| .. ...|...     ||     |.||| ....... ||.. |. | | |        . . || . ...|   |......   ||....|.||  
KIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM-

PPIIHGNINAKNILLDNENNEP----ILIDFGLSYKS-IDLLTNQKTQFISPCFITPEYFYKKTKNKISKEADIFSFGSTISNMIKGGTDFKED--EEGF
  |||  .   |||.| .|...     ..||||. .  .   .  .|   .| .. ||   . . .......|..|.| ..  |. | . |...  ... 
-GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV-IR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-

EELKRTFAGVLT---SRDKVSFDYRSLFTEINKDEPCFRPSSKELLKSFWFVEPPQPS
 . .  .. ..    ..|    . .|.|. ..  . .         . .|.. . ...
HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------F-HWTF-HNWSE
Kinase SAMK-D.AA CAMK-Unique 134-282 18 1.2e-10 31.17 In-house 1-220 (363) Show / Hide 
Range on Protein: 134-282
Range on HMM: 1-220/363
Sequence Identity: 18% (40 aa)

YQYIETISKNKFCEIEKYKKSQTKVNEYIIIKKI-----IKNST-------------LNEEKLINEIDTIYLLDHPNLIKIIGY----CKDKN-------
|  .. | .. |... . . . |..   . ..|      .|. .               . || .|..   ..||||.||. ..      |..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------YFYIGMKYYETFKFKQSNISK-------------------FGKNFE--QVIRKISFKILSAIDYLHSLEPPIIHGNINAKNILLDNE-----
        |.|| | | .    ..  ..                     |.  |    .. |....|||. |.||.   |.|... . ||.. ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQD--IVHRDLKLENIMVCYSFKDNN

----------NNEPILIDFGLS
          |.   |.||||.
HHRDFPYDWSNWHIKLCDFGLC
Kinase SAMK-D.AA TKL-Unique 246-325 29 3.9e-09 28.55 In-house 124-215 (290) Show / Hide 
Range on Protein: 246-325
Range on HMM: 124-215/290
Sequence Identity: 29% (27 aa)

DYLHSLEPPIIHGNINAKNILLDNENNEPI----LIDFGLSYKSIDLLTNQKT--------QFI-SPCFITPEYFYKKTKNKISKEADIFSFG
.|||..||||||...  .|.|.||..|.      ..|||||  .   ... ..         .. |.  . || .     ...|. .|..|||
YYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNF-CQYSEKSDVYSFG
Kinase SAMK-D.AA CAMKL 241-282 46 2.3e-08 22.62 In-house 136-176 (297) Show / Hide 
Range on Protein: 241-282
Range on HMM: 136-176/297
Sequence Identity: 46% (20 aa)

ILSAIDYLHSLEPPIIHGNINAKNILLDNENN-EPILIDFGLS
|.||..|.||.   |.|  | . |||||. .|    .||||.|
IVSAVNYCHSHG--IVHRDIKPENILLDENGNNNIKIIDFGFS
Kinase SAMK-D.AA TyrKc 134-391 16 3.1e-07 -105.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 134-391
Range on HMM: 1-280/280
Sequence Identity: 16% (51 aa)

YQYIETISKNKFCEIEKYKKSQTKVNEYIIIKKIIKNSTLNEEKLINEIDTIYLL--DHPNLIKIIGYCKDK-------NYFYIGMKYYETFKFKQSNIS
 . ....    |.|. | . .     .   .|.. ...   .| ...|.     |  .|||.....|.| ..          .| | | .    |.   .
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KFGKNFEQVIRKISFKILSAIDYLHSLEPPIIHGNINAKNILLDNENNEPILI---DFGLSYKSIDLLTN------QKTQFIS---PCF--IT-----PE
. .|   .   .... | .  .||||   ..||  . | |.|.....     .   ||||   | |.         ...   .    .   .      ||
HRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENH----TVKISDFGL---SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

YFYKKTKNKISKEADIFSFGSTI-----------SNMIKGGTDFKEDEEGFEELKRTFAGVLTSRDK---------VSFDYRSLFTEINKDEPCFRPSSK
 .    ..| . . |..||| ..           ..||.    .....| .| .|.   . .   .           .  |. . ..  . .|  ||. .
CI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQ--GYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFS

ELLKSF
|. . |
EIHECF
Kinase SAMK-D.AA TKL-Unique 136-214 22 6e-06 17.17 In-house 1-83 (290) Show / Hide 
Range on Protein: 136-214
Range on HMM: 1-83/290
Sequence Identity: 22% (19 aa)

YIETISKNKFCEIEKYKKSQTKVNEYIIIKKIIKNSTLNE--EKLINEIDTIYLLD-HPNLIKIIGYCK----DKNYFYIGMKYYE
 ...|  ...... |.|  ...|   |..... ...  ||  ....||. ..  |. |||. ...|||.    . ....| | |..
FWNKIGEGGYGQVYKGKWRGYPVA--IKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCP
Kinase SAMK-D.AA CAMKL 166-210 20 0.016422 3.66 In-house 31-100 (297) Show / Hide 
Range on Protein: 166-210
Range on HMM: 31-100/297
Sequence Identity: 20% (14 aa)

KIIK--NSTLNEEKLIN--------------EIDTIYLLD---HPNLIKIIGYCKDKNY------FYIGM
|||.    .... .. |              ||    .|.   ||| ||.     ....      .|. |
KIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM
Kinase SAMK-D.AA CAMK-Unique 377-393 47 0.031653 2.92 In-house 347-363 (363) Show / Hide 
Range on Protein: 377-393
Range on HMM: 347-363/363
Sequence Identity: 47% (8 aa)

EPCFRPSSKELLKSFWF
.| .| |.||||.. |.
DPDHRWSAKELLEHQWI
Kinase SAMK-D.AA STE 377-393 31 0.074117 2.49 In-house 341-359 (359) Show / Hide 
Range on Protein: 377-393
Range on HMM: 341-359/359
Sequence Identity: 31% (6 aa)

EPCFRPSSKELLK--SFWF
.|  ||....|||    ..
DPNKRPTASQLLKSEHPFI