Scy2

Species: Slime mold
Alias: DDB0231323, Scy2, DdisK129
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
Scy2.AA Protein None 1125 None Fasta, JSON
Scy2.kin_dom Protein Kinase Domain None 312 None Fasta, JSON

Protein domain

Protein domains of Scy2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Scy2.AA SCY1 42-348 33 1.6e-147 496.35 In-house 1-337 (337) Show / Hide
Range on Protein: 42-348
Range on HMM: 1-337/337
Sequence Identity: 33% (113 aa)

WKIYQSTKKTTNTECSLFVFEKKLYEKVSK-SNLENVITFLKKEATTLQRLRHPSILQVVSVMEETKTHIHFATEPILATLEDLLGYYRQRKKSTVD---
|||...|||.|..|||.|||.||..||..| |. |....||||.|..|.|||||.|||.....||.|.....|||.|...||..|......|.....   
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ

-----QSSQSEEGYKKKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKDLKWKLGG---------LGFTCSIETKEPPISNLSLQDLR
     |..|....|.|||....|||...|||||||.| ||.......|.||.|||||..|. .||.||         ..|.|.|....|.......|..|
DVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWR

EYQYISGGGGGESSNNSNYILPQLDYLAPEFISQ-------------RKFETNSDLFSIGRLIFELSINLEQKALDSHLISQLPKLGVISYYNTMIEQVR
|..|||...............|..|.||||.|..             .|....||.||.|.||... ....... ... . . .........|.|.....
EMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNP-YSTFHRYMEQWNAMSHCWW

RQSTMNTQRSDSAKVCTILLGDPMLRGDLENFIRSSFF
.. ....|.......|..|  ||..| |...|.....|
DHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF

Kinase Scy2.AA S_TKc 30-348 15 1.3e-09 -36.0 SMART 1-231 (231) Show / Hide
Range on Protein: 30-348
Range on HMM: 1-231/231
Sequence Identity: 15% (51 aa)

HDLKEVVGQDKFWKIYQSTKKTTNTECSLFVFEKKLYEKVSKSNLENVITFLKKEATTLQRLRHPSILQVVSVMEETKTHIHFATEPILATLEDLLGYYR
 .. ...|.  | | |. ..| |. .. . .                    ...|   |.. .|| | .   |...  .|... .| .   | ||. | .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIK

QRKKSTVDQSSQSEEGYKKKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKDLKWKLGGLGFTCSIETKEPPISNLSLQDLREYQYIS
.|..             ....| | | . .  . ||...| .. .  . .|| . || |....    |..  |. . .                      
KRGR-------------HGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------------------

GGGGGESSNNSNYILPQLDYLAPEFISQRKFET-NSDLFSIGRLIFELSINLEQKA-LDSHLISQLPKLGVISYYNTMIEQVRRQSTMNTQRSDSAK-VC
          . ..   ..|.||| .   .. .  .|  |.| ...|.   |  .   . ..   . |.|                      |..||   
----------TTFCGT-PWYMAPEVL---GYGKCKCDWWSCGCILYEM---LCGYPPFP-QMQMMFKKIG----------------------SPEAKDFI

TILLG-DPMLRGDLENFIR-------SSFF
  .|  ||  |       .         .|
RKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase Scy2.AA Ciliate-E2-Unclassified 164-276 17 5.1e-09 27.45 In-house 151-263 (352) Show / Hide
Range on Protein: 164-276
Range on HMM: 151-263/352
Sequence Identity: 17% (23 aa)

QILDGLLFLNQTAKLLHRNISPESIFITKDL---KWKLGGLGF-----TCSIETKEPP-------ISNLSLQDLREYQYISGGGGGESSNNSNYILPQLD
|||.|| .| .  . .||.| || |.....    . |. ..|.     ... .. .         ..... .    ..|..                   
QILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMP-Q-----------------

YLAPEFISQRKFE----TNSDLFSIGRLIFEL
|.||| . . . .      .| .| | ...|.
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM

Kinase Scy2.AA Ciliate-E2 30-276 15 9.5e-08 22.66 In-house 1-289 (365) Show / Hide
Range on Protein: 30-276
Range on HMM: 1-289/365
Sequence Identity: 15% (49 aa)

HDLKEVVGQDKFWKIYQSTKKTTNT------------------ECSLFVFEKKLYEKVSKSNLENVITFLK---------KEATTLQRLRHPSILQVVSV
 .. .. ||  | ..|. ... ..                   ..  . ...| ..|  . .....|  ..         .|   |..| || |.. . .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

MEE-TKTHIHFATEPILA-TLEDLLG--YYRQRKKSTVDQSSQSEEGYKKKDFTFEELELKAGIFQILD---------------GLLFLNQTAKLLHRNI
 .| ....| . .| .   .|.|..   .  . .. .           | .   | | | |  . |||.               .| .| .  . .||.|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-----------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDI

SPESIFITKDLKWKLGGLGF--TCSIE----TKEPPISNLSLQDL----REYQYISGGGGGESSNNSNYILPQ-------------LDYLAPEFISQRK-
 || |..      |.  .|.   ....    |.  ..... ..      | . |..                |             . |.||| ..  | 
KPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD----------------QIIQQNMFNTICGTPGYMAPEILNGKKY

--------FETNSDLFSIGRLIFEL
          . .|..|.| ...|.
DNQQKQKGYDYKCDIWSLGVILYEM

Kinase Scy2.AA CDKL 162-203 39 1e-05 15.57 In-house 104-145 (286) Show / Hide
Range on Protein: 162-203
Range on HMM: 104-145/286
Sequence Identity: 39% (17 aa)

IFQILDGLLFLNQTAKLLHRNISPESIFIT-KDLKWKLGGLGF
..||| .. |...  . .||.| || |.|| |.   ||.. ||
MWQILKAINFCHK-HNCIHRDIKPENILITPKNGQVKLCDFGF

Kinase Scy2.AA TyrKc 30-329 14 1.5e-05 -132.66 SMART 1-280 (280) Show / Hide
Range on Protein: 30-329
Range on HMM: 1-280/280
Sequence Identity: 14% (49 aa)

HDLKEVVGQDKFWKIYQSTKKTTNTECSLFVFEKKLYEKVSKSNLENVITFLKKEATTLQRL--RHPSILQVVSVMEETK------THIHFATEPILATL
  |... |   | ..|. | |       . |  |.| |          .  . .||  . .|  .|| |.. . |  . .        .   .|  .. .
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVME--YMPH

EDLLGYYRQRKKSTVDQSSQSEEGYKKKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKDLKWKLGGLGFTCSIETK---EPPISNLS
 ||. | | ...                   .   .|    .|| .|  .| .  .. || .    . .....  | .  | .  |. .           
GDLKDYLRKHRPK------------------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------

LQDLREYQYISGGGGGESSNNSNYILP----QLD------YLAPEFISQRKFETNSDLFSIGRLIFEL---------S-----INLEQ--KALDSHLISQ
                    .. |. .    . .       .||| |  .|| | || .| | ...|.               .. ..  . ...     
-------------------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP

LPKL--------GVISYYNTMIEQVRRQSTMNTQRSDSAKVCTIL
 |.              |. ...|  .      .|   . .. ..
QPPNDYPMSFVCCPDEMYQ-IMKQCWHEDP--EDRPTFSEIHECF

Kinase Scy2.AA C8 164-273 19 3.8e-05 13.94 In-house 131-226 (226) Show / Hide
Range on Protein: 164-273
Range on HMM: 131-226/226
Sequence Identity: 19% (23 aa)

QILDGLLFLNQTAKLLHRNISPESIFITKDLKW----KLGGLGFTCSIETKEPPISNLSLQDLREYQYISGGGGGESSNNSNYILPQLDYLAPEFISQ--
|..||. ..... . .|| | |. . .  | .     ||  .||   ..  .  |     .                       .  . |.||| ...  
QMIDGVNYIHCK-NIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNT----------------------CGTWAYFAPEIEKKQD

---RKFETNSDLFSIGRLI
   ....  |||||.| . 
NQYKQYRIQSDLFSVGLVL

Kinase Scy2.AA DCAMKL 30-110 16 7.6e-05 10.41 In-house 1-90 (279) Show / Hide
Range on Protein: 30-110
Range on HMM: 1-90/279
Sequence Identity: 16% (15 aa)

HDLKEVVGQDKFWKIYQSTKKTTN-TECSLFV---------FEKKLYEKVSKSNLENVITFLKKEATTLQRLRHPSILQVVSVMEETKTHI
 ..  ..|   |  ..  ....|. ... . .         |  |..... |... .   .   |   .|...|| | | . .. .|.||.
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHW-DTETHY

Kinase Scy2.AA CAMK-Unique 30-100 15 0.000109 11.18 In-house 1-82 (363) Show / Hide
Range on Protein: 30-100
Range on HMM: 1-82/363
Sequence Identity: 15% (13 aa)

HDLKEVVGQDKFWKIYQSTKKTTNTECSLFVFEK------KLYE--------KVSKSNLENVITFLKKEATTLQRLRHPSILQVV
... ...|.  | ..|  . ..| ...   ...|      |...        |.. . ...    ||.|.  .... || |....
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMK---LKREHQIWKMVDHPNIIKLY

Kinase Scy2.AA RTKF 251-276 50 0.00017 10.11 In-house 180-205 (272) Show / Hide
Range on Protein: 251-276
Range on HMM: 180-205/272
Sequence Identity: 50% (13 aa)

APEFISQRKFETNSDLFSIGRLIFEL
||| | .|.|   ||  | | . |||
APEAIMHRRFTQKSDVWSFGMMLFEL

Kinase Scy2.AA Ciliate-E1 146-193 31 0.000272 10.41 In-house 99-145 (202) Show / Hide
Range on Protein: 146-193
Range on HMM: 99-145/202
Sequence Identity: 31% (15 aa)

YKKKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKD
...... | .... . |||..|||  | |  ...||.| |. | |...
CQQNQNQFTFQQKMQIIFQLIDGLIELHQ-YNIIHRDIKPQNILINNQ

Kinase Scy2.AA NEK-Unclassified 148-202 29 0.000434 9.09 In-house 89-142 (258) Show / Hide
Range on Protein: 148-202
Range on HMM: 89-142/258
Sequence Identity: 29% (16 aa)

KKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKDLKWKLGGLG
||   |.|. ..    |.   . .  |  | .||   |  || |.|.   .|  |
KKNEPFDEGRIMQWCIQMIMAVQYIHQ-RKIIHRDLKPQNIFLTDDDTVSMGDFG