Gene DDB0216378 (Slime mold)

DDB0216378

Species: Slime mold
Alias: DDB0216378, DdisK176
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: Ste20-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
DDB0216378.AA Protein None 1142 None Fasta, JSON
DDB0216378.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of DDB0216378.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0216378.AA STE20 20-276 50 1.2e-163 549.95 In-house 1-288 (288) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-288/288
Sequence Identity: 50% (146 aa)

FELIEEIAEGSFGTVYKGKHLPTGNI----MAVKIIALDED----ETFEDLVVEIDILNRCNHNNIVKYYGSWVKG----DELFIAMECCGGGSITEIYQ
.||.|.| .||.|.|||. | |||..     |.|.. |...    . .||.. ||.|...|.| |||||||| .|.    |||.|.|| |||||.|.|..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---ELNI-----PLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDK----S--SKRNTFIGTPYWMAPEVIEN-RSN
   ....     |.||.||||.|||.|.||.|||. ..||||.|..||||||.|.||||||||.. |.|    .  .|||||.|||||||||||.  ...
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

PVPYDTKADIWSLGITLIELAEAEPPLSEIHPMKVLFQIP--YRDPPKLKN--QENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
  .||.|.||||||||.||.|| |||....|||...|.||   ..||.||.  ....|..| .|. .||||||..| ||..||||||.
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase DDB0216378.AA STE 20-276 38 1e-139 470.5 In-house 1-359 (359) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-359/359
Sequence Identity: 38% (139 aa)

FELIEEIAEGSFGTVYKGKHL------PTGNI---------MAVKIIALDED-----------------ETFEDLVVEIDILNRCN--HNNIVKYYGSWV
.|.||.| .|.||||||...       .||..         ||.|.. |...                 | ....  ||.|...||  | |||||||. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KG-------DELFIAMECCGGGSITEIYQ---ELNIPLN----------ESQIAYVCRETLKG-LEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSG
|.       |||.|.|| ..|||...|..   . . |||          ||||||.||..||| |.|||  ..||||.|.|||||     |||.||||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LLDK-----------------SSKRNTFIGTPYWMAPEVIENRSNP--VPYDTKADIWSLGITLIELAEAEPPLSEIHPMKVLFQIPYR-----------
 |..                 ..|||||.||| |||||||......   .||||.||||||.|.||.|. .||... |||...|.||             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DPPKLKN-----------------QENYSKDFINFIQSCLQKDPNQRKTATELLK--HPFV
    .||.|..                 ....|..|..||. |||||||.| ||..|||  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase DDB0216378.AA YSK 20-276 51 3.9e-135 409.49 In-house 1-257 (257) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-257/257
Sequence Identity: 51% (135 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDE-TFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGGSITEIYQE-LNIPLNESQ
|   | |  |||| ||||    |. . |.||| |...|   ||.  || .|  |   .| |||||  |.  | | || |||||.          .. |..
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLD-KSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIELAEAE
|| . || ||||.|||  ..|||| | ||.||.|.|||||.||||.| .   . |||||.|||||||||||      . ||.|||||||||| .|.|  |
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEV--SYYDFKADIWSLGITAYEMAKGE

PPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
||... |||.|.| || . ||||.  ..||| |..|.  || |||.|| .| ||||| |.
PPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase DDB0216378.AA MST 20-276 51 1.1e-130 417.59 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-254/254
Sequence Identity: 51% (133 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWV--KGDELFIAMECCGGGSITEIYQELNIPLNESQ
|...| . .||.| |||  |. ||.| |.|..  .||  ....  || |.  |.  .|||||||    |  .. | || ||.||.  |    ...||| |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNED--LQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQ

IAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSG-LLDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIELAEAE
|| ... ||.||.|||    ||||.| .|||| . |  ||||||||| | |   ||||.||||||||||||..    . ||.|||||||||| ||.|| .
IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQE----IKYDCKADIWSLGITAIEMAEGM

PPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
||.|.|||| ..| || . ||..|. | .| .|..|. .||||.|.||.||..||.|||.
PPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase DDB0216378.AA KHS 20-276 48 4.6e-106 357.78 In-house 1-258 (258) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-258/258
Sequence Identity: 48% (127 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGGSITEIYQELNIPLNESQIA
.||.  .  | .| ||| ..  .... |||.| .. .. |. .  || ..  | | ||| |.||... | |.|.|| |||||. .||. .  ||.| |||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYH-VTGPLSELQIA

YVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKS-SKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIELAEAEPP
|||||||.||.|||    .|||.||||||||..|||||||||||. .  . .||  ||||||||||||     .   |.   |||..||| |||||  ||
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK-GGYNQLCDIWAVGITAIELAELQPP

LSEIHPMKVLFQIPYRD--PPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
. ..|||..|| .   .  |||||... .|. | .|.. .| |.| .| ||. ||.||||
MFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase DDB0216378.AA PAKL 20-276 43 5.70000000001e-105 355.03 In-house 1-256 (256) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-256/256
Sequence Identity: 43% (114 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKG-DELFIAMECCGGGSITEIYQELNIPLNESQI
||. |   .||.|.|||. |  |.  .|.| | . |    .|.  ||.||  |.  ||| |.||   . ... | |. |  |||  . .     ||| ||
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

AYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKSSK--RNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIELAEAE
. . . ||||| |||  |.|||| | |||||.| ..||.||||||  |. .     |  ||||||||||.|       .|. |.||||||||.||.|. .
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQ----NYNNKCDIWSLGITAIEMADGF

PPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
||.... ||. .  || . ||...|   .|. | .|.  |..|||..|  . .|| ||| 
PPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase DDB0216378.AA SLK 20-276 49 2.2e-104 353.08 In-house 1-259 (259) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-259/259
Sequence Identity: 49% (127 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGGSITEIYQELNIPLNESQIA
.|.| |. .| || ||| .|  .. . | |.| ....|  || .||||||  |.| |||| |...   ..|.. .| |.|| . .|  ||. || |.||.
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

YVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSG-LLDKSSKRNTFIGTPYWMAPEVIE-NRSNPVPYDTKADIWSLGITLIELAEAEP
|||.... .|..||. .|||||||  |||.|  |||.|||||||  .  .  || |||||||||||||.    .   ||| |||||||||||||.|. ||
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
| .|. ||.||..|   .||.|..   .||.| .|.. ||.|||..| |. .|..|..|
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase DDB0216378.AA PAKA 20-276 40 2.5e-104 352.89 In-house 1-260 (260) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-260/260
Sequence Identity: 40% (106 aa)

FELIEEIAEGSFGTVYKGKHLPTGNI--MAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGGSITEIYQELNI----PL
.. .|.| .|. |.||... . |..    |.| ......   | .. || ... |.|.|||.|. | .  |||...||  .||. |.. .. .     ..
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

NESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDK-SSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIEL
.|.||||||||.|.|||..| ...||||.|  ||||   |.||..|||    | .  .||||  |||||||||||  .     || | ||||||| .||.
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ----YDEKVDIWSLGIMAIEM

AEAEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
.| |||  .  | . .. |     |..|.... |..| .|   ||..|. .| .|.|||.||| 
IEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase DDB0216378.AA S_TKc 20-276 34 8.20000000001e-103 348.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGG--GSITEIYQELNIP-----
.|....| .|.||.|||..|  || |.|.|||        |..  ||.|| . .| ||||.|....  |.|.. ||.|.|  |.  .. .. . .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDT-KADIWSLGITLIE
..| ............|||.|  ..|||||| .||||.|   .|..|||.. .|      .||.|||..|||||.       .|.. |.|.||.|..|.|
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYE

LAEAEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLK-------HPFV
..  .|| .    |...|..              |.....||. ||||||..| || |.|.       ||..
MLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0216378.AA MSN 20-276 49 1.2e-101 336.49 In-house 1-265 (265) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-265/265
Sequence Identity: 49% (131 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNR-CNHNNIVKYYGSWVK------GDELFIAMECCGGGSITEIYQEL-NI
|||.| .  | .| ||||.|  ||.. |.|.. . |||  |..  ||..| .  .| ||. ||| ..|       . |.. || || ||.|.. ..  . 
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEE-EEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQ

PLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKSS-KRNTFIGTPYWMAPEVIENRSNP-VPYDTKADIWSLGITL
 | |  |||.||| |.|| .||.  |||||.|| |.|||.. .||| |||||  ||.   .||||||||||||||||.   ||   || ..|.||.||| 
SLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITA

IELAEAEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
||.||..||| ..|||. || ||   |||||  . .|| | ||...|| |.  || .. ..|||||.
IEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase DDB0216378.AA Pkinase 20-276 31 1.3e-89 308.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFED--LVV--EIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGG----SITEIYQ-ELN
..... | .||||.|||..|  || | ||||| .....  .|  ..   || |..|.|| |||..|...  .|.. . ||.|.||    .  .. . . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IPL--NESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDV----KLADFGVSGL--LDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADI
 ..   | ..  .....|.||||.|  ..|||||| .|||. . |..    |..|||.. .  . ..|  .|| |||..||||||       .|..|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDM

WSLGITLIELAEAEPPLSEI----HPMKVLFQIPYRDPPKLKNQENYS---------------------KDFINFIQSCLQKDPNQRKTATELLKHPFV
||.|..|.|..  .|| ..     . .  .. |  . .|.|. .. ..                     .... || .||.|||..| ||...|.||..
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0216378.AA NinaC 20-276 44 6.1e-89 301.78 In-house 1-267 (267) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-267/267
Sequence Identity: 44% (119 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNR-CNHNNIVKYYGSWVK-----GDELFIAMECCGGGSITEIYQEL---N
.| .|.|. | .| |.| | .  | | ||||   ..|   |.   |  ||   |.| |.|..|| . |     ||.| . || | |||.|.. . |    
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHD-EEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCG

IPLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKS-SKRNTFIGTPYWMAPEVIE-NRSNPVPYDTKADIWSLGIT
  ..|  |||. .|.. ||  ||   ||||| || |||||  | ||| |||||  ||    .||| .|||.|||||||    .    ||  .|.||||||
RRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGIT

LIELAEAEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPFV
 |||.  .||. ..|||. .|.||   ||.|   || ...|  ||  || ||  .| . ...|.|||.
AIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase DDB0216378.AA Pkinase_Tyr 20-231 28 7.3e-32 108.53 Pfam 1-228 (270) Show / Hide 
Range on Protein: 20-231
Range on HMM: 1-228/270
Sequence Identity: 28% (67 aa)

FELIEEIAEGSFGTVYKGKHL----PTGNIMAVKII--ALDEDE-TFEDLVVEIDILNRC-NHNNIVKYYGSWV-KGDE--LFIAMECCGGGSITEIYQE
 ...... ||.||.||||.       |.   |||..    ....   ||.  |. |.    .| |||..||  . .|.   ..| || . .|.  .  ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

L---NIPLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLL----DK-SSKRNTFIGTPYWMAPEVIENRSNPVPYDTKA
    . ||. ...   |..  ||.|||.  | |||||   |.|.||.. || .||| . ..        .. ..      |||||.| ..     . || 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK----FTTKS

DIWSLGITLIELAE-AEPP-LSEIHPMKVLFQI
|.|| |... |.    | |   .. .  |. .|
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase DDB0216378.AA TyrKc 20-276 25 9.9e-18 63.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVVEIDILNRC--NHNNIVKYYGSWVKG-------DELFIAMECCGGGSITEIYQELN
 .|.... || ||.||||.        ||| .  |     ||.  |. |. .   .| |||. ||  ...       . |.| || . .|.  .  ..  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

IPLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKS-----SKRNTFI----GTP-----YWMAPEVIENRSNPVPY
  |. ..  . |    .| ||||. |.|||||   |.|..| . || .||| |  ..       ||         |.       |||||.|  .     .
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK----F

DTKADIWSLGITLIELAE--AEPPLSE----IHPMKVLFQIPYRDPPKLKNQEN--------YSKDFINFIQSCLQKDPNQRKTATELLKHPFV
 || |.|| |... |.    ..|.  .    . .  |. ..  ..   ..  .|         ...  . ...| . ||..| | .|.  | . 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY--RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF