Gene MkcB (Slime mold)

MkcB

Species: Slime mold
Alias: DdisK158, MkcB, DDB0191334
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MKC

Sequence

Name Sequence Type Origin Length Description Download
MkcB.AA Protein None 714 None Fasta, JSON
MkcB.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of MkcB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MkcB.AA MKC 438-687 61 1.9e-204 685.5 In-house 1-260 (260) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-260/260
Sequence Identity: 61% (161 aa)

YKDSDQVGKGGFGTVYFAKS-----TKEKRLVAIKKMPHVTKRQQQQNFREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAKA-WKFN
||...|||||||||||.||.     |..|..|||||||||||..|..|..|...|..|.||||||.|..|...|...|.|||||.|||.|||... .||.
YKFLHQVGKGGFGTVYCAKYNNPHSTYDKCRVAIKKMPHVTKKHQRNNLNEIGFLNYCNHPNIVKYHCSHMKHDDEIWMVMEFMQGGTLEEASQNSHKFC

ENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVAT-STPMHMVGSPFWMAPEMIQQKYHSTPVDIWSFAISLLEMANQRPP
|...|||.||.|.||.||||...||||||||||||...|..||||||||.||.. ....||.||||||.|||||||.||.|.|||||.|.||||||.|||
ESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIHMCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMANGRPP

MMESAVKAMFTVATDGATG---FDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPFI
...|..||||.|||.|...   ||||..|||||.|||..||..||..|.|||.|||||||
HHKSRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPFI
Kinase MkcB.AA STE20 438-687 36 3.4e-127 428.86 In-house 1-288 (288) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-288/288
Sequence Identity: 36% (104 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRL----VAIKKMPHVTK----RQQQQNFREAAILAKCDHPNIVKLHTCHIDK---DSNLWIVMEFMEGGTFEEAAK
|.. ...|.|..|.||.|  .. ...    ||||||.. ..     ... .. |  |...|.|||||| ..... .   |..||||||...||.  .. |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

A----------WKFNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVAT-------STPMHMVGSPFWMAPEMIQQ----
.          ...||   ||. .|.|.||.|||.||..|||.|..||... .|.|||.|||.| .. .       ..  ..||.|.|||||.||.    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-KYHSTPVDIWSFAISLLEMANQRPPMME-SAVKAMFTVA--TDGATGFDD--PALWSDCFKDFLSLCLKQDPAERATAEELLKHPFI
 | . . .||||. | ..|||. .||... ....|||...  . .   . |  |  ||..|.||...|| .||..|.||..|||||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase MkcB.AA STE 438-687 30 1.5e-108 366.96 In-house 1-359 (359) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-359/359
Sequence Identity: 30% (111 aa)

YKDSDQVGKGGFGTVYFAKST------KEKRL---------VAIKKMPHVTK-----------------RQQQQNFREAAILAKCD--HPNIVKLHTCHI
... ...|||.||||| |.        | ...         .|||.|.. ..                  ..||  .|  |. ||.  |||||| . |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DK------DSNLWIVMEFMEGGTFEEAAKA---------------WKFNENNLAYVAKELLKG-LQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCE
..      |..|||.||.|.||....  |                ..|.|. .||.....||| |.|||..| .|||.|.|||..     |||.|||.| 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

DVATS------------------TPMHMVGSPFWMAPEMIQQ------KYHSTPVDIWSFAISLLEMANQRPPMME-SAVKAMFTVATDGATG-------
 .. |                     ..||.| |||||.|||      | ..| .||||. . ..|||. .||... .  .|||  .. .. .       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---------FDD----------------PALWSDCFKDFLSLCLKQDPAERATAEELLK--HPFI
          |.                |  ||..||||...||. || .|.||..|||  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase MkcB.AA S_TKc 438-687 30 8e-89 302.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQQQQNFREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEG--GTFEEAAKAWK------
|.  ...|||.||.|| .. .| .|.||||...       ..  || .|| | .|||||||. .  |  ..|..|||...|  |.  .  |  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMHMVGSPFWMAPEMIQQKYHST-PVDIWSFAISLLEMANQ
 |.|   ..........|.|.|... .||||| .||...    .|..||||.  .     ....|.|..||||..    ... ..|.||. . | ||.  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

RPPMMESAVKAMFTVATDGATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLK-------HPFI
.||     ...|| .              |. .|||.. ||. ||..| || |.|.       ||..
YPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MkcB.AA Pkinase 438-687 29 9.9e-79 272.67 Pfam 1-293 (293) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQ--QQQNFR--EAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGG----TFEEAAK---
|.   ..|.|.||.|| ..  .. ..||.|... ....   .|...|  |..|.....|||||.|. .  | ......|||..|||       .  .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

AWKF--NENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKV----KLIDFGLCE---DVATSTPMHMVGSPFWMAPEMIQ-QKYHSTPVDIWS
  .|   |. .  .....|.||.|.|..  .|||||..||... .| .    |..||||..       | ... .|.|..|||| |. ..|....||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FAISLLEMANQRPPMMES------AVKAMFTVATDGATGFDDPAL-------------------WSDCFKDFLSLCLKQDPAERATAEELLKHPFI
. . | ||.. |||  ..        ..|.    .. . || | .                   ||. .|||.. ||..||..| |||..|.||..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MkcB.AA PAKA 438-687 38 1.5e-78 267.25 In-house 1-260 (260) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-260/260
Sequence Identity: 38% (101 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRL--VAIKKMPHVTKRQQQQNFREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAKAWK------
||  ...|.|. |.|| |...| .    ||||.|   .  . .    | ... .| |.|||.    ..  |. ||.|||.||||   .  ..        
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGGCLTDVITQCCNIQCNY

FNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVAT--STPMHMVGSPFWMAPEMIQQKYHSTPVDIWSFAISLLEMANQ
..|.  ||| .| |.||...|..| .|||.|| || .  .|.||. ||| |       .    ||| | ||||| |..|  .  |||||  | ..||.  
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

RPP-MMESAVKAMFTVATDGATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPFI
 || . |  ..||...|| |.  . ||. ||. |.|||..||. |. .||.|.|||.|||.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase MkcB.AA YSK 482-687 38 4.2e-67 200.97 In-house 46-257 (257) Show / Hide 
Range on Protein: 482-687
Range on HMM: 46-257/257
Sequence Identity: 38% (83 aa)

REAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAKA---WKFNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFG
.|  .|. || |.| |       ||. |||.||.  ||      |.    .| |   | . .|.|||| |||.. ..||| |.||. .| .|.||| |||
QEIQFLSQCDSPYITKYYGSYL-KDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFG

LCEDVA-TSTPMH-MVGSPFWMAPEMIQQ--KYHSTPVDIWSFAISLLEMANQRPPMME-SAVKAMFTVATDGATGFDDPALWSDCFKDFLSLCLKQDPA
    .  |..    .||.|.||||| |.|   |  . .||||  |  .|||.  ||  .  . ..|| .  .      .   .|. ||.|  .||. ||.
VAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPE

ERATAEELLKHPFI
.| .|.||||| ||
QRPSAKELLKHKFI
Kinase MkcB.AA STE11 438-687 29 1.3e-65 224.28 In-house 1-303 (303) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-303/303
Sequence Identity: 29% (88 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQ---QQQNFREA-----------AILAKCDHPNIVKLHTCHID--KDSNLWIVMEFMEGGTF
..  .  ||| ||||| .  ..  .|.|.|... .  .|   .|... ..           ... . .|.|||. . | ..  ..... | ||...||. 
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

EEAAK-AW---KFNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGK-VKLIDFGLCEDVATSTPM--H----------MVGSPF--------
..  .  |   ||.|.   .  | .|.||||||... .|||.| |||..  .|  .||.||| .  .|.....  .          | |.|.        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEMIQQKY---HSTPVDIWSFAISLLEMANQRPPMMES---AVKAMFTVATDGATGFDDPALWS------DCFKDFLSLCLKQDPAERATAEELLKH
|||||.| |     .....||||.    .|||  .||  .    .  ||| ...   .    |   |      .  .|||..|...|| .|.|| .||.|
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PFI
|||
PFI
Kinase MkcB.AA PAKB 439-687 37 1.1e-61 211.21 In-house 2-252 (252) Show / Hide 
Range on Protein: 439-687
Range on HMM: 2-252/252
Sequence Identity: 37% (96 aa)

KDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQQQQN---FREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAKAWKFNENNL
..  ..| |  |.|  |.    .|.||.|||     | ||     | |  |.    |||||..   .   |  ||.||||||||       .   ||   
DNYVKIGEGSTGIVCIATEKHTGRQVAVKKM---DLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGD-ELWVVMEFMEGGALTDIVTHTRMNEEQI

AYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMH--MVGSPFWMAPEMIQQKYHSTPVDIWSFAISLLEMANQRPPMM-
|.| .  |. | |||    .||| ||  |..   |.||| ||| |  |   .|    .|| |.|||||.|      | |||||. | ..|| .  ||   
ATVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFN

ESAVKAMFTVATDGATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPFI
|. ..||  .       . . .  |   ..||. .| .||..|.||.|||.|||.
EPPLQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase MkcB.AA TAO 438-687 34 2.7e-60 195.56 In-house 1-254 (254) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-254/254
Sequence Identity: 34% (90 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQQ---QQNFREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAKAWK-FNEN
..|   .| | || ||||. .. . .|||||| .  |. .   |   .|   | .  |||... . |.. ...  |.|||.  |   .      | . | 
FQDLREIGHGSFGAVYFARDKHTEEVVAIKKMSYSGKQSHEKWQDIIKEVRFLQQVKHPNCIEYKGCYL-REHTCWLVMEYCLGSASDILDVHKKPMQEV

NLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMHMVGSPFWMAPEMI---QQKYHSTPVDIWSFAISLLEMANQRPP
 .| .... |.||.|||. .|.|||.| .||... .| ||| |||    |.       || |.|||||.|           ||.||  |  .|.|  .||
EIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSASMVCPA--NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPP

MME-SAVKAMFTVATDGATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPFI
. .  |. |.. .|   .   . .  |||||..|.  ||.. |.|| .|||.|.|.|.
LFNMNAMSALYHIAQNDSPTLQQNE-WSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase MkcB.AA Ciliate-E2 438-687 22 1.6e-57 196.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVA--------------------IKKMPHVTKRQQQQNFREAAIL----------------AKCDHPNIVKLHTC
||   . |.|.||.|| .|  |.....|                    |. |  . |.| .| ..|  |.                 . .||||.|.. |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

HID-KDSNLWIVMEFMEGGTFEE--------------AAKAWKFNENNLAYVAKELLK---------------GLQYLHENH-MVHRDLKSANIMMSVEG
 .. .|.|. .|||. .||. ..                .  .|.|.  .|. |..|.               .|.|||...  .|||.|  ||..    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

KVKLIDFGLCEDVATS---------------------TPMHM------------VGSPFWMAPEMIQ---------QKYHSTPVDIWSFAISLLEMANQR
 .|.|||||. .. ..                     ||  |            .|.|  ||||...         ||.... .||||. . | ||   .
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPMMESAVKAMFTVATDGATGFD----------------DPALWSDCFKDFLSL----CLKQDPAERAT-AEELLKHPFI
||         .    ..   |.                ..  ||.  ||...     .|. || .| | .|..|.||..
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase MkcB.AA MST 592-687 44 2.5e-36 112.93 In-house 158-254 (254) Show / Hide 
Range on Protein: 592-687
Range on HMM: 158-254/254
Sequence Identity: 44% (43 aa)

VGSPFWMAPEMIQQKYHSTPVDIWSFAISLLEMANQRPPMME-SAVKAMFTVATDGATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPFI
.|.|.||||| ||.    . .||||  |. .|||  .||  .  .. |||   .    .| ||  ||. | ||.. || ..| .|.|||.||.||||
IGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase MkcB.AA MST 438-578 34 1.6e-29 90.96 In-house 1-142 (254) Show / Hide 
Range on Protein: 438-578
Range on HMM: 1-142/254
Sequence Identity: 34% (50 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQQQQNFREAAILAKCDHPNIVKLHTCHI-DKDSNLWIVMEFMEGGTFEEAAKAWK--FNENN
.   .  | | .| || |   . . .||||..|       |.   |  |.  |. ..|||.    .  |.. .|||||. ..|    . |. .  .||  
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQ

LAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFG
 | . .  |.|||||| |. .|||.|..|| .. ||  || |||
IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFG
Kinase MkcB.AA Pkinase_Tyr 445-624 28 6.1e-26 88.48 Pfam 8-207 (270) Show / Hide 
Range on Protein: 445-624
Range on HMM: 8-207/270
Sequence Identity: 28% (58 aa)

GKGGFGTVYFAKST----KEKRLVAIKKMPHVTKRQQ--QQNF-REAAILAKC-DHPNIVKLHTCHIDKDSN--LWIVMEFMEGGTFEE--AAK---AWK
|.| ||.|| .. .    ..|  ||.|.... .  .|  .. | |||.|. .  .|||||.|. . .|..    ..||||.|..|   .   ..     .
GEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQP

FNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDV-----A-TSTPMHMVGSPFWMAPEMIQQKYHSTPVDIWSFAISLLE
..   |   . .  ||..||......||||   |.. . ...||  ||||. |.       ...   .    .||||| |. .  .|  |.||| . . |
LTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWE

M
.
I
Kinase MkcB.AA TyrKc 438-687 24 2.9e-21 77.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 438-687
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIKKMPHVTKRQQQQNFREAAILAKC--DHPNIVKLHTCHIDK------DSNLWIVMEFMEGGTFEEAAKAWK
 .  .. | | ||.|| .. .   . ||.|.. . .   ..   ||| |. |   .|||||.|. . ...      .  |.||||.|..|   .  .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

--FNENNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATS------TPMHMV----GSP-----FWMAPEMIQQKYHSTPV
  ..   | . .    .| .|||... .||||   |.. . .. ||  ||||. |.         . . ..    |.       ||||| |. .  .|  
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIWSFAISLLEMAN--QRPP--MMESAVKAMFTVATDGATG--FDDPAL--------WSDCFKDFLSLCLKQDPAERATAEELLKHPFI
|.||| . . |.    | |.  | .  ..  . |  .  .|   . |.          .|   .  . | . ||..| | .|.  | ..
DVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase MkcB.AA YSK 438-467 36 1.2e-05 12.58 In-house 1-30 (257) Show / Hide 
Range on Protein: 438-467
Range on HMM: 1-30/257
Sequence Identity: 36% (11 aa)

YKDSDQVGKGGFGTVYFAKSTKEKRLVAIK
..  . .|.| || || .   . .| ||||
FTKQECIGRGSFGEVYKGIDNRTQRVVAIK