Gene PakB (Slime mold)

PakB

Species: Slime mold
Alias: MIHCK, DDB0191345, DdisK166, Ddpak, PakB
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
PakB.AA Protein None 852 None Fasta, JSON
PakB.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of PakB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PBD PakB.AA PBD 355-412 38 5.9e-22 79.14 Pfam 1-60 (60) Show / Hide 
Range on Protein: 355-412
Range on HMM: 1-60/60
Sequence Identity: 38% (23 aa)

SVGSP-FNVKHNIHVNYHSVTG-FEGLPKEWEVILQSSGITREDVVEHSEVVIDVLDFHM
 ...| .|.|| .||.... || |.|.|.||. .||||||....  .... |.||..|..
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD PakB.AA PBD 356-390 31 1.9e-09 38.62 SMART 1-38 (38) Show / Hide 
Range on Protein: 356-390
Range on HMM: 1-38/38
Sequence Identity: 31% (12 aa)

VGSPF-NVKHNIHVN-YHS-VTGFEGLPKEWEVILQSS
...|. |.|| .||.      ..|.|||..|...|...
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase PakB.AA PAKA 571-823 61 3.4e-185 621.53 In-house 2-260 (260) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-260/260
Sequence Identity: 61% (159 aa)

EGSTKIGEGAAGEVFVVTQLKTNNK--VAIKKMPLNQQNMK-LIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILEQFNSVKLV---
.  .|||.||.|||.|.|..|||..  ||||.| ...|..| ||..||..||.|.|.||..||||||| | |||.||.|.|||||....|.......   
KFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYMD

EAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEP
|.|||||| |.|.|| .|||.|||||||||||||||.|||||..|||..||||...||| |.||||||||||.||...||.|||||||||||.||.|.||
EGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGEP

PYMSFPPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
||...|||||..||.|.|.||.||..|||..|.||..|||..||..|..|. ||.||||
PYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase PakB.AA STE20 571-823 49 6.9e-157 527.5 In-house 2-288 (288) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-288/288
Sequence Identity: 49% (143 aa)

EGSTKIGEGAAGEVFVVTQLKTNNK----VAIKKMPLNQQN-----MKLIVTEIGIMKSCRHQNIIDYIDSYLVG----DSLWVAMEFMGGGCLTEILEQ
|   |||.|. |.|....  .|...    ||||||.|....     ...|..|| ||| |.|.||. |..|||..    |.||..||..|||.||.|...
ELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKH

FNSVK-------LVEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTK----SKQ-KRVTIVGTPYWMAPELIRG-----
... .       . |.||||.| |.|.||.|.||.|.||||||.|||||..||.|||||||..|||||    ..| || |.||||||||||.|..     
CMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPD

QNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLIT--TKGIPDLKD--QNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
..|| |.|||||||.|.|||| ||||. ..|.||.|.|.  ... |.|||  ..|||..|.|||.|||.||.|.|| |. ||.|||.
KGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase PakB.AA STE 570-823 35 5.4e-129 434.85 In-house 1-359 (359) Show / Hide 
Range on Protein: 570-823
Range on HMM: 1-359/359
Sequence Identity: 35% (130 aa)

GEGSTKIGEGAAGEVFVVTQL------KTNNK---------VAIKKMPLNQQN------------------MKLIVTEIGIMKSCR--HQNIIDYIDSYL
 ||  |||.|| |.|.           ||...         .|||.|.|...|                  |. |  || ||| |.  |.||. |...|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VG-------DSLWVAMEFMGGGCLTEILEQFNSVKLV------------EAQIAYVCAETLKG-LAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAA
..       |.||..||.|.||.|..|...  ...              | ||||.| ..||| |.|.||.|.||||||..||||     |||.||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTKS----------------KQKRVTIVGTPYWMAPELIRG------QNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLITTK-----------
|||.|                .||| |.|||| ||||| |..      . ||.|.||||||....|||. .||.. ..|.||.|.|...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GIPDLKD-----------------QNKWSDDFKDFVKKCLDKDVENRPEAKVLLN--HPFL
    ..| |.|                 . |||..||||..|||.|| ..|| |. ||.  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase PakB.AA MST 575-823 46 6.1e-104 331.27 In-house 6-254 (254) Show / Hide 
Range on Protein: 575-823
Range on HMM: 6-254/254
Sequence Identity: 46% (116 aa)

KIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQNMKLIVTEIGIMKSCRHQNIIDYIDSYL--VGDSLWVAMEFMGGGCLTEILEQFNSVKLVEAQIAYVC
|.|.|. | |.  . ..|.. ||||..|     .  |  || ||. |  ..|  | .||.      .|  ||. |.| .  |    . . | |.||| ..
KLGQGSYGSVYKAIHKQTGKIVAIKMVPV-NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRT-LNEQQIACIL

AETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSFPPL
  ||.||.| |. ..||||||. ||||  .|  |||||| ..|||    || | .||||||||| |  . || |.||||||| | ||||..|||  . | 
YDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDIHPM

RALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
||.|.| .| .| .||  .||..| |||.||| |. | |. |. ||.||| 
RAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase PakB.AA YSK 571-823 44 1.6e-101 306.47 In-house 2-257 (257) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-257/257
Sequence Identity: 44% (115 aa)

EGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQN--MKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILEQFNSVKLVEAQI
    .|| |  |||.     .|.  ||||   | .      .|  || .  .|  ..|  |. ||| . .||. ||. ||| .   . .    .. | .|
TKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYI

AYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELIRG--QNYDRKVDIWSLGIMAMEMAESEPPY
| .  | |||| |.||.  ||||||. |.||  .| |||.||| |.|.| . .|| | ||||||||||.|      || |.||||||| | |||  ||||
AIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPY

MSFPPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
    |.|..|||  .  | |... ..|. ||.||  ||.|| |.|| || || | | 
CDYHPMRVMFLIPKNNPPKLEGR-SYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase PakB.AA PAKB 571-823 49 2.5e-100 339.59 In-house 2-252 (252) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-252/252
Sequence Identity: 49% (126 aa)

EGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPL-NQQNMKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILEQFNSVKLVEAQIA
.   |||||  | | . |.  |   ||.||| |  ||   |   |. ||   .|.||..  .|||||| ||| |||| || || |  .   . . | |||
DNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGDELWVVMEFMEGGALTDIVTH---TRMNEEQIA

YVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSF
.||   |. ||| |.|  |||||||| ||| .|| ||| |||. ||. |   ||   ||||||||||.|  . |. .||||||||| .|| . |||| . 
TVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNE

PPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
|||.|.  |  .  | ||.. | |   ..|. ..| .|.. |  |. ||.||||
PPLQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase PakB.AA KHS 571-823 45 4.6e-91 306.54 In-house 2-258 (258) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-258/258
Sequence Identity: 45% (119 aa)

EGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLN-QQNMKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILEQFNSVKLVEAQIA
|   ..| |  |.|.   . .... .|.| . .. ......|  || .|| ||| ||. |. |||  | ||..||. ||| | .| .     .| | |||
ELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHV--TGPLSELQIA

YVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELI---RGQNYDRKVDIWSLGIMAMEMAESEPPY
||| |||.||.|.||. ..|||||  |||| ..| ||||||| .||.| .  ||   .|||||||||     |   |..  |||..|| |.|.||  || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

MSFPPLRALFLITTKGI--PDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
    |.|||||.|  .   | |||..|||. | .||| .| |.   || |. ||.|||.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase PakB.AA S_TKc 570-823 32 2.8e-90 307.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 570-823
Range on HMM: 1-231/231
Sequence Identity: 32% (86 aa)

GEGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQNMKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGG--GCLTEILEQFNSVK----L
 |   |||.|| |.|. ..  ||. .||||...      . |  || |.|. .| ||. ..|..   |.|.. ||...|  | | ..... .. .    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

VEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELIRGQNYDR-KVDIWSLGIMAMEMAES
 | ............|.|.||.. ||||.| .|||| .   .|..||| |.||        |..|||..||||..    |.. |.|.||.|..  ||.  
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

EPPYMSFPPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLN-------HPFL
.||.     . ..| .              |...|||..|||.|| |.|| |  .|.       ||..
YPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PakB.AA FRAY 571-823 36 9.5e-87 269.44 In-house 2-277 (277) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-277/277
Sequence Identity: 36% (101 aa)

EGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQN---MKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILE-QFNSVK----
|    ||||| . |.    .  . ..|||   |   .   |. .. ||  | .| | |.. |  |..| ..||. | . ..| .  |.   ..  .    
ELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHKQ

--LVEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTK----SKQ-KRVTIVGTPYWMAPELIRGQN-YDRKVDIWSLGI
  . |. || .  |.|||| | |.  .||||||..|||.|.||.. .||||  | | .    |..  | |.|||| ||||| .   . || |.||||.||
GVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFGI

MAMEMAESEPPYMSFPPLRALFLITTKGIPDLKD--QNK-----WSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
 |.|.|   .||  .||   | |.     | |    ..|     ..  ||. ..||| || ..|| |  || | | 
TAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase PakB.AA Pkinase 570-823 30 2.9e-83 287.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 570-823
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

GEGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQNMKLIVT-----EIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGG----CLTEILEQFNS
 .   |||.|. |.|.  .  .|. .||.|....  ....  .|     || |||...| ||. ..|..  .|.... ||...||     | ....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VKL--VEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSV----KLADFGYAAQL-TKSKQKRVTIVGTPYWMAPELIR-GQNYDRKVDIWSL
 ..   | ..  .. ..|.||.|.||.  ||||.|..|||. ..| .    |..||| |.|. . ...   |..|||..||||.|| || |..|||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIMAMEMAESEPPYMSF----PPLRALFLITTKGIPDLKDQNKWS---------------------DDFKDFVKKCLDKDVENRPEAKVLLNHPFL
|..  ||.  .||. .     . .. ...|  .. |.|. .  |.                     ...|||.|.||.|| . || |. .|.||..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PakB.AA SLK 567-823 39 8e-78 262.12 In-house 2-259 (259) Show / Hide 
Range on Protein: 567-823
Range on HMM: 2-259/259
Sequence Identity: 39% (103 aa)

KLFGEGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQ-NMKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILEQFNSVKLVE
.. ||    .|.|| | |    .  ..   | | . .... ...  . || |. .| | ||.. ...| . . ||. .|| .|| . .|.   . . | |
EIIGE----LGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHP-LTE

AQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELI-----RGQNYDRKVDIWSLGIMAMEMA
 ||.||| ... .| ..||.. ||||.|  |||.  || |.||||| .|....  ||| | .|||||||||..     . | || |.|||||||  .|||
DQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMA

ESEPPYMSFPPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
. |||.    |.| |. |     | |.   .|| .||||.||||.||..||. ...|..|...
QMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase PakB.AA PAKL 571-823 41 1e-76 261.19 In-house 2-256 (256) Show / Hide 
Range on Protein: 571-823
Range on HMM: 2-256/256
Sequence Identity: 41% (105 aa)

EGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQ-NMKLIVTEIGIMKSCRHQNIIDYIDSYLVG-DSLWVAMEFMGGGCLTEILEQFNSVKLVEAQI
|   | |.|. | |. ..   ||   ||| ...      | |  || | | |. .||. |  |   . . .|. |..   |    ..|      | |.||
EFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKT-LNEKQI

AYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQ-KRVTIVGTPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYM
. .   ||||| | ||.  ||||||. ||||  |. ||.||||   ||  .       ..||||||||| |  |||. |.||||||| | |||...||  
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

SFPPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
  || ||.  |  .  | ...  .||  | ||. .|. || | |. .  || |||.
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase PakB.AA Pkinase_Tyr 575-711 29 6.9e-18 61.2 Pfam 104-254 (270) Show / Hide 
Range on Protein: 575-711
Range on HMM: 104-254/270
Sequence Identity: 29% (44 aa)

KIGEGAAGEVFVVTQL----KTNNKVAIKKM--PLNQQN--MKLIVTEIGIMKSC-RHQNIIDYIDSYL-VGDS--LWVAMEFMGGGCLTEILEQ--FNS
|.|||| |||.  |      .|. .||.|..     ...  ..    |. |||.  .|.||. ..   .  |..  ... ||.| .|.| . | .   . 
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDK

VKLVEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFG
 .|   ..   |..  ||..| .|.. ||||.   |.|..... || .|||
QPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase PakB.AA TyrKc 573-823 23 1.1e-17 63.15 SMART 4-280 (280) Show / Hide 
Range on Protein: 573-823
Range on HMM: 4-280/280
Sequence Identity: 23% (67 aa)

STKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQNMKLIVTEIGIMKSC--RHQNIIDYIDSYLVG-------DSLWVAMEFMGGGCLTEILEQFNSVKL
  |.|||| |||.  |      .||.|..  .   .. .  |. ||..   .|.||.  .   . .       . |.. ||.| .|.| . |       |
GKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-L

VEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKS-------KQKRV--TIVGTP----YWMAPELIRGQNYDRKVDIW
  ..  . |    .| .|.||.. ||||.   |.|.|... || .||| .  ..         . .|.  .  |       ||||| |.   .  | |.|
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SLGIMAMEMAES-EPPYMS-----FPPLRALFLITTKGIPDLKDQNK------WSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
| |..  |.    ..||        .. ... .. . . ..  . .        .|.  .  |.| . | |.||  . .  | ..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PakB.AA Pkinase_Tyr 732-754 47 0.006036 10.6 Pfam 180-202 (270) Show / Hide 
Range on Protein: 732-754
Range on HMM: 180-202/270
Sequence Identity: 47% (11 aa)

WMAPELIRGQNYDRKVDIWSLGI
||||| |.   .  | |.|| |.
WMAPECINYGKFTTKSDVWSFGV