Gene PakC (Slime mold)

PakC

Species: Slime mold
Alias: DdisK167, DDB0202066c, PakC
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKA

Sequence

Name Sequence Type Origin Length Description Download
PakC.AA Protein None 478 None Fasta, JSON
PakC.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of PakC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH PakC.AA PH 15-111 34 4.5e-23 83.91 SMART 1-82 (82) Show / Hide 
Range on Protein: 15-111
Range on HMM: 1-82/82
Sequence Identity: 34% (33 aa)

PDKEGELKKQGHVVKNWKKRKFIIQNDMLFYFKDKEERPVGAVPLRMSRCYENKSLGKPNCFELVSPRINKTFFIQANTPDEMASWMKAVEKGSEYS
. ||| |.|..    .|||| |.. ||.|.|.|||  .| | .||.  ...| .      |||...     |...|.....|| .||.| .| .. .
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDCTVRE-P------CFEIHH-DR--TYYFQCESEEEMQEWMQAIQKAIHNN
PH PakC.AA PH 15-109 34 1.3e-22 84.18 Pfam 1-92 (92) Show / Hide 
Range on Protein: 15-109
Range on HMM: 1-92/92
Sequence Identity: 34% (33 aa)

PDKEGELKKQGHVVKNWKKRKFIIQNDMLFYFKDKEERPVGAVPLRMSRCYENKSLGKPNCFELVSPRINKTFFIQANTPDEMASWMKAVEKGSE
. |||.|.|.|   |.|||| |...|. |.|.||. .|| | .||.  .... .. ..|.||....    .|...||....|| .||.| .. . 
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DR-RTYYFQAESEEEMNDWMQAIQSACR
PBD PakC.AA PBD 112-169 38 6.1e-17 61.76 Pfam 1-60 (60) Show / Hide 
Range on Protein: 112-169
Range on HMM: 1-60/60
Sequence Identity: 38% (23 aa)

TVSQP-FNLKHEVHVDFNSATGFS-GLPKEWEVILKSSNVSKQEVLDKPSEWLSVLEFQA
 .| | .| || .|| ... |||  |.|.||. .|.||. ||.|  . |.  ..|. |. 
MISTPLTNFKHTMHVGWDGQTGFFTGMPPEWQKLLQSSGISKPEQKHNPQAVFDVVQFYQ
PBD PakC.AA PBD 113-147 39 7.2e-11 43.36 SMART 1-38 (38) Show / Hide 
Range on Protein: 113-147
Range on HMM: 1-38/38
Sequence Identity: 39% (15 aa)

VSQPF-NLKHEVHVD-FNS-ATGFSGLPKEWEVILKSS
.| |. | || |||  ..   ..| |||..|...||..
ISTPTGNFKHIVHVGPWDGQTGEFTGLPHQWQHLLKHC
Kinase PakC.AA PAKA 205-459 60 1.1e-188 633.14 In-house 1-260 (260) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-260/260
Sequence Identity: 60% (159 aa)

YKNMTKIGEGAAGEVFVATSSKNNKR--VAIKKIEINNDNAK-LLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMS-
||.|.|||.||.|||.|||..|.|..  ||||.....|.. | |...||..||...|.|||||||||.| |.||||.||.|.||||||......||... 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGGCLTDVITQCCNIQCNY

--EIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELIRGHDYGVKVDIWSLGIMMMEMAEG
  | |||||..|.|..|..||| |||||||||||||||..|||||.|||..|||||.||||||.||||||||||.||...|. ||||||||||..||.||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

EPPYMDFPPLRALFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
||||...|||||..||.|.|.|..|...|||..|.||..|||...| .|..|..||.|||.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase PakC.AA STE20 205-459 46 9.5e-157 527.04 In-house 1-288 (288) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-288/288
Sequence Identity: 46% (134 aa)

YKNMTKIGEGAAGEVFVATSSKNNKR----VAIKKIEINND----NAK-LLVTEIAIMKTSHHDNIVNYIDSYIVN---DRELWVAMEFMGGGCLTDILE
|... |||.|. |.|..|.  ....     |||||......    . . ....|| ||| ..| |||.|..||...   | |||..||..|||.||||..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

AFDNIK-------MSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQ-----KQQKRNTVVGTPYWMAPELIRG----
.. ...       |.| ||||. .|.|..|.|.|| |.||||||.|||||...|.||.||||..||||.     .|.||||.||||||||||.|..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-HDYGVKVDIWSLGIMMMEMAEGEPPYMDFPPLRALFLIT--TKGIPPLKE--TTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
 ..|. |.|||||||. .|||||||||.|..|.||.|.|.  ... |.||.  ..|||. |.|| .|||......|| |..|||||| 
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase PakC.AA STE 205-459 33 6.00000000001e-129 434.68 In-house 1-359 (359) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-359/359
Sequence Identity: 33% (123 aa)

YKNMTKIGEGAAGEVFVATSSK---------------NNKRVAIKKIEINNDN------------------AKLLVTEIAIMKTSH--HDNIVNYIDSYI
.... |||.|| |.|. |   |               .....|||.....|.|                   . .  || ||| ..  |.|||.|...|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VNDR------ELWVAMEFMGGGCLTDILE-AF---DNIK--------MSEIQIAYVVKETLKA-LQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAA
....      |||..||.|.||.|.||..  .   .. .        ..| ||||.....||. |.|.||.|.||||||..||||     ||..||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTQK----------------QQKRNTVVGTPYWMAPELIRG------HDYGVKVDIWSLGIMMMEMAEGEPPYMDFPPLRALFLITTK-----------
|||..                ||||||.|||| ||||| |..      ..|..|.||||||....|||.|.||..|..|.||.|.|...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GIPPLKE-----------------TTKWSKTFQDFFSKCLDINVANRPDATDLLK--HPFM
    ..|||..                 ..|||. |.|| .|||...  .||.|..|||  ||| 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase PakC.AA MST 205-459 45 6.4e-107 340.91 In-house 1-254 (254) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-254/254
Sequence Identity: 45% (116 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINND-NAKLLVTEIAIMKTSHHDNIVNYIDSYI-VNDRELWVAMEFMGGGCLTDILEAFDNIKMSEI
.  . |.|.|. | |. |.  ...| ||||.. .|.| ..  .  || ||.    ..|| | .||.   . ..|  ||. |.| . ||  .  ..  .| 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQE--IIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKIT-QRTLNEQ

QIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELIRGHDYGVKVDIWSLGIMMMEMAEGEPPY
||| . . ||. ||| |. ..||||||. ||||  ||  | |||| ..|||  . |||||.||||||||| |    |  |.|||||||   |||||.|||
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPY

MDFPPLRALFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
 |. | ||.|.| .| .| .|. ..||  | || .||| .|   |. |..||.||| 
SDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase PakC.AA YSK 205-459 43 5.2e-99 298.75 In-house 1-257 (257) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-257/257
Sequence Identity: 43% (113 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKI--EINNDNAKLLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMSEI
..   .|| |  |||. .   . .. |||| |  |   |   ..  || .       .| .|. ||   |  ||. ||. ||| . | . .    .. |.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYL-KDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEK

QIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELIRG--HDYGVKVDIWSLGIMMMEMAEGEP
.|| . .| ||.| |.||   ||||||. |.||  .| ||..||| |.|.|. |.|||| ||||||||||.|      |  |.|||||||   ||| |||
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEP

PYMDFPPLRALFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
|| |  |.|..|||  |  ||  |  ..|| | .|   ||. . ..|| | .|||| | 
PYCDYHPMRVMFLI-PKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase PakC.AA PAKB 206-459 47 3.4e-96 325.88 In-house 2-252 (252) Show / Hide 
Range on Protein: 206-459
Range on HMM: 2-252/252
Sequence Identity: 47% (121 aa)

KNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINNDNAK-LLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMSEIQI
.|  |||||  | | .||     . ||.|| .        ||  |. ||   .|.|||.  .|| |.| |||| |||| || ||||  .     | | ||
DNYVKIGEGSTGIVCIATEKHTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYQHPNIVEMYSSYLVGD-ELWVVMEFMEGGALTDIVTHT---RMNEEQI

AYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELIRGHDYGVKVDIWSLGIMMMEMAEGEPPYMD
|.| .  |.|| | |.   |||||||| ||| . | ||  |||. ||. .   ||   ||||||||||.|    || .|||||||||..|| .|||||  
ATVCRQVLQALAYLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFN

FPPLRALFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
 |||.|.  |  .  | ||.. | |   ..| ...|  ... |  | .||.|||.
EPPLQAMKRIRDMHPPRLKNHHKVSPRLREFLDRMLVRDPNQRWTAQELLRHPFL
Kinase PakC.AA S_TKc 205-459 32 4e-95 323.24 SMART 1-231 (231) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINNDNAKLLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGG--GCLTDILEAFDNIK----
|. . |||.|| |.|. ..  | ...||||.|       . .  ||.|.|  ||.|||...|..     .|.. ||...|  | | |...     .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELIRGHDYGV-KVDIWSLGIMMMEMAE
..| ...........||.|.||.. ||||.| .|||| .   .||.||| |.||       .|..|||..||||..    ||  |.|.||.|... ||. 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GEPPYMDFPPLRALFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLK-------HPFM
|.||.     . ..| .              |. . || .|||. . ..|| | ..|.       ||..
GYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PakC.AA Pkinase 205-459 30 8.3e-87 299.49 Pfam 1-293 (293) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINNDNAKLLVT-----EIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGG----CLTDILEAFD
|.   |||.|. |.|. ..  ...|.||.|.|.  ... . ..|     ||.|||  .|.||| ..|..   ...... ||...||     | |.... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

NIKM--SEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSV----KIADFGYAAQL-TQKQQKRNTVVGTPYWMAPELIR-GHDYGVKVDIWS
. ..  || ..  .....|..|.|.||   ||||.|..|||. ..| .    ||.||| |.|. . ...  .|..|||..||||.|| | .|| |||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGIMMMEMAEGEPPYMDF----PPLRALFLITTKGIPPLKETTKWS---------------------KTFQDFFSKCLDINVANRPDATDLLKHPFM
.|... ||. |.||. .     . .. ...|  .. |||..   |.                     ....|| ..||. . . || |...|.||..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PakC.AA KHS 205-459 44 7.3e-86 288.77 In-house 1-258 (258) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-258/258
Sequence Identity: 44% (115 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEIN-NDNAKLLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMSEIQ
|  . ..| |  |.|. |   . .. .|.| | .. .|. ...  || .||. .| ||| |. ||. .|. ||..||. ||| | || ..    ..||.|
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDK-LWICMEYCGGGSLQDIYHVTG--PLSELQ

IAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELI---RGHDYGVKVDIWSLGIMMMEMAEGEP
|||| .|||..|.|.||  ..|||||  |||| ..| ||.|||| .||.|.   ||   .|||||||||     |   |.   |||..||  .|.||  |
IAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQP

PYMDFPPLRALFLITTKGIPP--LKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
|  |  |.|||||.|  .  |  ||. .|||.|| .|   .|  |   || |. ||.|||.
PMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase PakC.AA FRAY 205-459 36 2.1e-84 262.01 In-house 1-277 (277) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-277/277
Sequence Identity: 36% (102 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINNDN---AKLLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILE-AFDNIK--
|.    ||||| . |. |     . ..||| |.    .    . |. ||  |   || |.| |  |..||. |||. | . ..| . ||.   .  ..  
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNE-ELWLVMRYLECGSCLDIMKFKMPQGEPH

----MSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQ-----KQQKRNTVVGTPYWMAPELIRGHD-YGVKVDIWSL
    . |  || . ||.||.| | |.  .||||||..|||.|..|.. |||||  | | .     ..  | | |||| ||||| .     |  |.||||.
KQGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSF

GIMMMEMAEGEPPYMDFPPLRALFLITTKGIPPLKETT--K-----WSKTFQDFFSKCLDINVANRPDATDLLKHPFM
||  .|.| | .|| ..||   | |.     | | .    |     ....|..  .|||    ..|| |  |||| | 
GITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase PakC.AA MKC 205-459 36 1.2e-82 280.89 In-house 1-260 (260) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-260/260
Sequence Identity: 36% (98 aa)

YKNMTKIGEGAAGEVFVATS-----SKNNKRVAIKKIEINNDNAKLLV-TEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDN-I
||.  ..| |. | |. | .      ....||||||. .    ..  .  ||.. .   | ||| |. |....| |.| .|||| || |.   ||  |  
YKFLHQVGKGGFGTVYCAKYNNPHSTYDKCRVAIKKMPHVTKKHQRNNLNEIGFLNYCNHPNIVKYHCSHMKHDDEIWMVMEFMQGGTLE---EASQNSH

KMSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQ-KQQKRNTVVGTPYWMAPELIRGHDYGVKVDIWSLGIMMMEMA
|  | .|||| || |..|.| |... .|||.|| ||   ..| .|. |||  . ..  |.. .   .| |.||.|| |..  ..  .||||.||   |||
KFCESCIAYVCKEMLQGLMYLHEHNIVHRDLKSANIMMNTDGEIKLIDFGLCIDVSHEKEEIH--MCGSPFWMSPEMIQQKQHSYPCDIWSFGICLLEMA

EGEPPYMDFPPLRALFLITTKGIPP---LKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
 |.||...  .. | |.  | |.     .. ...||  | || ..||  . . || |. |||||| 
NGRPPHHK-SRMKAMFMVATNGCKFPKEFDDPCHWSDCFHDFLWQCLQMDPHKRPTAEQLLKHPFI
Kinase PakC.AA MSN 205-459 40 1.9e-78 258.65 In-house 1-265 (265) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-265/265
Sequence Identity: 40% (108 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINNDNAKLLVTEIAIM-KTSHHDNIVNYIDSYIV-----NDRELWVAMEFMGGGCLTDILEAFDNIK
.. .  .| |. |.|.     |  . .||| .....|.   . .|| .. | ||| ||. |   .|      .|  ||. ||| | | .||..    .  
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQS

MSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQKQQKRNTVVGTPYWMAPELIRGHD-----YGVKVDIWSLGIMMM
. |  |||. .| |. |...|. . ||||||  |.||  .  ||. ||| .||| .   .||| .||||||||| |   .     |  . |.||.||  .
LKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITAI

EMAEGEPPYMDFPPLRALFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
|||||.||  |. |.||||||  .  | ||   |||| |..|  |||  |   ||.. ..|||||.
EMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase PakC.AA TyrKc 205-459 23 9.7e-24 86.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 205-459
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YKNMTKIGEGAAGEVFVATSSKNNKRVAIKKIEINNDNAKLLVTEIAIMKTS--HHDNIVNYIDSYIVND-------RELWVAMEFMGGGCLTDILEAFD
 .   |.|||| |||. .| .     ||.|..  .    . .  |. ||.    ||.|||. .  ... .         |.. ||.| .|.| | | .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NIKMSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQK-------QQKRNTV-VGTP-----YWMAPELIRGHDYGVK
.   .  .  .      .  .|.|| . ||||.   |.|.|... |||.||| .  .. .       . .| .   |.       ||||| |. . .  |
PK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

VDIWSLGIMMMEMAE-GEPPYMD-----FPPLRALFLITTKGIPPLKET-------TKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
 |.|| |..| |.   |..|| .      .. ... .. . . .|  .        .  .. .|   ..| . . ..||  ...  | ..
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase PakC.AA Pkinase_Tyr 205-347 28 7.3e-21 71.29 Pfam 1-156 (270) Show / Hide 
Range on Protein: 205-347
Range on HMM: 1-156/270
Sequence Identity: 28% (44 aa)

YKNMTKIGEGAAGEVFVATSS----KNNKRVAIKKIEINNDNA----KLLVTEIAIMKTS-HHDNIVNYIDSYIVNDRE--LWVAMEFMGGGCLTDILEA
 . . |.|||| |||. .|      ...  ||.|..  . .      . .  |..|||.  ||.|||...   .  ..   ... ||.| .|.| | | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

--FDNIKMSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFG
   |. . .  ..     .  |...| .| . ||||.   |.|..... |||.|||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase PakC.AA Pkinase_Tyr 368-418 35 3e-07 25.18 Pfam 180-232 (270) Show / Hide 
Range on Protein: 368-418
Range on HMM: 180-232/270
Sequence Identity: 35% (19 aa)

WMAPELIRGHDYGVKVDIWSLGIMMMEMAE-GEPP-YMDFPPLRALFLITTKG
||||| |.   . .| |.|| |. | |.   || | | . .. . . .|. .|
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG