Gene PakH (Slime mold)

PakH

Species: Slime mold
Alias: DDB0229408, PakH, DdisK172
External Links: DictyBase Link ,
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: PAKL

Sequence

Name Sequence Type Origin Length Description Download
PakH.AA Protein None 513 None Fasta, JSON
PakH.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of PakH.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PakH.AA PAKL 42-294 64 1.5e-217 729.0 In-house 1-256 (256) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-256/256
Sequence Identity: 64% (166 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIMLK-NKYWILMDYCSLSSFNDIMQSIGKTFKEKEI
||.|||||.||.||||.||||..|...|||..||.|.|....|.|||||||||..|..|||||||..| |.||||||||||.|.||.|.|..||..||.|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

SLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFS--KGSIAGTPYWMAPEILNQTDYNNKIDVWSLGIVAIELADGEPPLS
|.||||.|.||.|||||.|||||||.|||||.|..||||||||||||.|....  .....||||||||||.|...||||.|.|||||.|||.|||.||..
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

EVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
...||||||||...|||||..||.|||.|..|...|..||...||||..||.||||
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase PakH.AA STE20 42-294 46 1.7e-151 509.59 In-house 1-288 (288) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-288/288
Sequence Identity: 46% (134 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTS----IAIKEFEIFEA----NDVEPISKEIQILKKCNNPYVVSYFGSIMLK----NKYWILMDYCSLSSFNDIMQ
.|..||.|.||.|.||.|.||...      .|||  .. ..    ...| | |||.|.|.|..|..|.|.|| . .    .. ||.|.||.  |  |||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---SIGK-----TFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQS----TFS-K-GSIAGTPYWMAPEILNQ----
   ..||     ...|..|. |... | || ||||..|||||||..||||.| |.||.|||||..|...    |.. |  .. |||||||||....    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-TDYNNKIDVWSLGIVAIELADGEPPLSEVNPMRAMYMIG--RRPPPTFKD--PKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
  .|..| |.||||| |||.|.||||.....|||||.||   ..||||.||  |.||||||  ||||||.|| ..|...|||| ||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase PakH.AA MST 42-294 50 1.1e-135 433.77 In-house 1-254 (254) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-254/254
Sequence Identity: 50% (130 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIM--LKNKYWILMDYCSLSSFNDIMQSIGKTFKEKE
|.| ||||.||.||||.||||...   |||   .   .| . |.||| |.. |...|.| |.||      |  || | ||   | .|||  ...|. | .
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQ

ISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVS-QQIQSTFSKGSIAGTPYWMAPEILNQTDYNNKIDVWSLGIVAIELADGEPPLS
|..||.. |.|| |||.  .||||||..||||.. |  | |||||| |..  .  . .  ||||||||| ...  |..| | ||||| |||.| |.||.|
IACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYS

EVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
.. ||||| ||  .|||||||| .||.||  || |||.|. ..||.  ||| ||||
DIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase PakH.AA STE 42-294 33 3.3e-125 422.25 In-house 1-359 (359) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-359/359
Sequence Identity: 33% (123 aa)

FEIQEKLGEGSFGSVYRAIHK------SSNTS---------IAIKEFEIFEAN-----------------DVEPISKEIQILKKCN--NPYVVSYFGSIM
.|..||.|.|.||.||.|...      ...           .|||. .. . |                 ... | |||.|.||||   |..| |.|. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LK-------NKYWILMDYCSLSSFNDIMQ---SIGKTFK----------EKEISLILQQSLLG-LVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQ
 .       .. || | |..  |. ||..   ..||...          |..|. |..| | | | ||||..|||||||.|||||     ||..||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QIQS---------------TFSKG--SIAGTPYWMAPEILNQ------TDYNNKIDVWSLGIVAIELADGEPPLSEVNPMRAMYMIGRR-----------
|...               | ..   ...||| |||||...|       .|. | |.||||...||.|.|.||... .|||||.|| .            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPTFKD-----------------PKKWSPEFVSFVDKCLTKDINERWSPSQLLD--HPFI
    |||...|                 |.||||||  |..|||.|| |.|...||||   ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase PakH.AA YSK 42-294 45 5e-110 332.52 In-house 1-257 (257) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-257/257
Sequence Identity: 45% (118 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEAND-VEPISKEIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQS--IGKTFKEK
| .||. | |||| || .| .  .  .|||  .  .| | .| | .|||.|  |  ||.  |.|| .   | || | ||   |  | | .  .|. | ||
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQ-FDEK

EISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQ-STFSKGSIAGTPYWMAPEILNQ--TDYNNKIDVWSLGIVAIELADGEP
 |. ||   |.|| |||| . ||||||.||.|| | |.||..||||. ||  ..      .|||||||||.  |  . |. | |.||||| |.|.| |||
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEP

PLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
|.... |||.|  |  ..||. .. ...|  |  ||. || || ..| | ..|| | ||
PYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase PakH.AA PAKA 42-294 40 4.5e-98 332.11 In-house 1-260 (260) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-260/260
Sequence Identity: 40% (104 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTS--IAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQSIGK----TF
..  ||.|.|. |.||.|. .. |..  .|||  .. . .  | |  || ..|.|... .| |  |  .. . |. |.| .  .  |. .   .    ..
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

KEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQS-TFSKGSIAGTPYWMAPEILNQTDYNNKIDVWSLGIVAIELADGE
.|. |. .... | || ..|||..||||||| ||||.  |.|||.|||   |..   ... .. |||||||||.... .|. |.|.||||| |||...||
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGE

PPLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
||  . .| |||| |     | .||| |||.||  |.|||| .|  .|.| ..|| |||.
PPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase PakH.AA S_TKc 42-294 32 3.2e-93 316.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSL--SSFNDIMQSIGK-----T
.|| .|.|.|.||.||...||...   |||.         | | .||||||| . |..| .....   ..... |.||.    .  |.... |.      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSKGSIAGTPYWMAPEILNQTDYNN-KIDVWSLGIVAIELADG
| | ..  ...| ...| |.||..|||||.| .||||||  ..||.|||.. |.       .. |||..||||.|    |.  |.|.||.|.. .|.. |
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

EPPLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLD-------HPFI
.|| .  .... . .||             |||. .|..|||.|| ..|..  ..|        ||..
YPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PakH.AA Pkinase 42-294 29 7.1e-87 299.72 Pfam 1-293 (293) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISK----EIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSLS----SFNDIMQ-SIG
..| .|.|.||||.||...||...   |.|...  .... .....    ||||.|..| |..| .... . |..... |.||       .  |... . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTF--KEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQV----KIADFGVSQQ--IQSTFSKGSIAGTPYWMAPEILN-QTDYNNKIDVWSL
..|   |.|.  .. | | || |.||. |||||.|..|||.|..|..    ||.|||.. |  . .     ...|||..||||... ...|  |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVAIELADGEPPLSEV----NPMRAMYMIGRRPPPTFKDPKKWS---------------------PEFVSFVDKCLTKDINERWSPSQLLDHPFI
|.. .|.. |.|| ..     | .. |.|| |. .| .. .  |.                     .|. .|...||.|| ..|... |.| ||..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PakH.AA KHS 42-294 42 7.4e-85 285.34 In-house 1-258 (258) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-258/258
Sequence Identity: 42% (110 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQSIGKTFKEKEIS
.|.  ..| | .| ||.| .. |..  |.|   .   .|.. | .|| ..|.|  | .|.|||| . ..| || |.||   |  || .  |.  .|  |.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-LSELQIA

LILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSK-GSIAGTPYWMAPEIL---NQTDYNNKIDVWSLGIVAIELADGEPPL
 . .. | || ||||.. .||||| ||||| ..|.||.|||||| ||  | .|  |  |||||||||.     .  ||.  |.|..|| |||||.  ||.
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

SEVNPMRAMYMIGRRP--PPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
 .. ||||.... .    ||. || .|||. |  ||  .|||.   | ....|| |||.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase PakH.AA Ste20-DD1 42-294 43 1.3e-82 280.82 In-house 1-268 (268) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-268/268
Sequence Identity: 43% (118 aa)

FEIQEKLGEGSFGSVYRA-------IHKSSNTSIAIKEFEIFEANDVE---PISKEIQILKKCNN-PYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQS
| | |  | |||| |          .    |  ||.|  |. .| |||      ||| |||     ||.| | |  .  |   | | ||   |  |||| 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEM-NADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQM

IGKTFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQ-STFSKGSIAGTPYWMAPEILNQ----TDYNNKIDVWSLGI
 .|.  | .|  |. |   |||||||..|.|||||  |.|... || | ||||||  .    |    . | ||||.|||         |  | |.|||||
CSKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGI

VAIELADGEPPLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
 |||.|   ||. .||| |  . |  ..||| | |  |||||  |.  || ..   | |  ||| ||||
TAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase PakH.AA SLK 42-294 39 8.7e-81 272.26 In-house 1-259 (259) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-259/259
Sequence Identity: 39% (102 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKCNNPYVVSYFGSIMLKNKYWILMDYCSLSSFNDIMQSIGKTFKEKEIS
.||   ||.| || ||.| ||  .   | |  || . ...|    ||.|| .|. |..|  ... .  || |.....|     . ||  .... .|. | 
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

LILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSK-GSIAGTPYWMAPEI-----LNQTDYNNKIDVWSLGIVAIELADGEP
.. .. . .| .|||...||||.|  |||.   |.|..|||||| . ..|  |  .  |||||||||.     .  . |  | |.|||||  ||.|..||
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
| .|.|||| .  | .  ||| . | .|| ||  |. ||| || . ||. .||..|...
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase PakH.AA NinaC 42-294 40 6.7e-78 265.12 In-house 1-267 (267) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-267/267
Sequence Identity: 40% (109 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKK-CNNPYVVSYFGSIMLKNKY-----WILMDYCSLSSFNDIMQSI---G
.|| |  | | .| |...  | .   .|.|  .  .  |.| |  | .||.. |. | || ..|   .| |      |. | ||.  |  |. . .   |
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEE-IEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCG

KTFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSK-GSIAGTPYWMAPEIL-----NQTDYNNKIDVWSLGIV
.  .|. |. ||   ..||  ||. ..||||.|  ||||   | ||  ||||| |..||  . .   |||.|||||.        .||    ||||||| 
RRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGIT

AIELADGEPPLSEVNPMRAMYMIGRRPPPTFKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
||||.||.||. .  |||||. | | ||||   | .|. ||  |. .||.||   | . ...|.||||
AIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase PakH.AA Pkinase_Tyr 42-255 28 5.8e-34 115.64 Pfam 1-237 (270) Show / Hide 
Range on Protein: 42-255
Range on HMM: 1-237/270
Sequence Identity: 28% (67 aa)

FEIQEKLGEGSFGSVYRAIHK----SSNTSIAIKEF-EIFEAND--VEPISKEIQILKKC-NNPYVVSYFGSIM-LKNK--YWILMDYCSLSSFNDIMQS
 .. .|||||.||.||... |    . ..  |.|   |     .   |   .|..|.|.  ..| .|.. | ..  .    ..| | |. . .  |  ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

I---GKTFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQI----QSTFSKGSIAGTPY-WMAPEILNQTDYNNKIDVWS
    .. .. |..  . .|   |. ||.||..||||.   |.|..|...|||.||| .  |    .  . |.. .  |  ||||| .|   .. | ||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGIVAIELAD-GEPP-LSEVNPMRAMYMI---GRRPPP
 |..  |.   || |   .. . . . .|   |.| |.
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC
Kinase PakH.AA TyrKc 42-294 25 9.5e-23 82.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 42-294
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

FEIQEKLGEGSFGSVYRAIHKSSNTSIAIKEFEIFEANDVEPISKEIQILKKC--NNPYVVSYFGSIMLK-------NKYWILMDYCSLSSFNDIMQSIG
 .  .||||| || ||... |   .  |.|         .| . .|..|..|   ..| .|  .| .. .         ..|.| |... . .|  .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

KTFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQST----FSKGSIA-----GTP-----YWMAPEILNQTDYNNKI
.... |.   .  |   |  |||||..||||.   |.|..| ..|||.||| |  | .      ||  .      |.       ||||| .|   .. | 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVWSLGIVAIELA-DGEPPLSE-----VNPMRAMYMIGRR----PPPT-----FKDPKKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFI
|||| |..  |.  .|..| ..     ... ...  . ..    .||      |      ..|  .   .|   | ..| . |..  | ..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF