Gene ZakA (Slime mold)
ZakA
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| ZakA.AA | Protein | None | 781 | None | Fasta, JSON |
| ZakA.kin_dom | Protein Kinase Domain | None | 304 | None | Fasta, JSON |
| ZakA.kin_dom2 | Protein Kinase Domain | None | 264 | None | Fasta, JSON |
Protein domains of ZakA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | ZakA.AA | NZAK | 9-312 | 64 | 1e-204 | 686.38 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 9-312 Range on HMM: 1-329/329 Sequence Identity: 64% (212 aa) WEEISFIGEGQ-YGRVIKCRKKNGFILNEQVDYVAIKIISKDKFKRNETDILEKIRLFNIPRYYS----HAEDDNFIYIYMEYIEGENLANIL-KTKKQG ||||||||..| ..||.||||||..|.|||||.|..|||.|..|...|||||||||.|||||||| ||||||...||||..||.||...| ..|||. WEEISFIGGCQFFSRVKKCRKKNTEIANEQVDKVHCKIITKCDFFYHETDILEKIRHFNIPRYYSACIKHAEDDNYHCIYMEWMEGGNLTQFLMNDKKQL RFKESRIISMIADLVETLSFLHKHHVIHRDIKTANLVLDKNKNLKLIDFGASTIQNKKQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNN ||||.|||.||||..||.|.|||||.||||||..|..||.||||||||||.|.||...|||||||||||||||||||||||||||||||||||||.|||| RFKEHRIIKMIADIAETMSYLHKHHIIHRDIKSNNVILDFNKNLKLIDFGSSIIQQQYQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNENNNN INNINNNNDLNGSGSGISTYLNEQYKQSSFAIIGTFNYMAPEVKRNYRATRKSDVWSLGCTIIEMAGGDLS---------------QKLNGIPIIPDHLS |....||||||||||||||||....|.|.|||.||..|||||.|.|.|...||||||.|||...|.|.... ||.|.||.||.|.. ICDFGNNNDLNGSGSGISTYLSSNQKESKFAIGGTHHYMAPENKNNHRINEKSDVWSFGCTVWQMFGYNPPNTIYSPKEMASMVSDQKFNYIPQIPFHVP DTLKDFLNHCLVIDPKKR----SYMEELL |..|||...|..|||||| |.|.|.| DKMKDFITQCWDIDPKKRPKDFSHMIEKL |
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| Kinase | ZakA.AA | Dicty3 | 13-312 | 42 | 2.3e-163 | 543.53 | In-house | 1-351 (351) | Show / Hide |
Range on Protein: 13-312 Range on HMM: 1-351/351 Sequence Identity: 42% (156 aa) SFIGEGQ-YGRVIKCRKKNGFILNEQVDYVAIKIISKDKFK-----RNETDILEKIRLFNIPRYYS--HAEDDN--FIYIYMEYIEGENLA------NIL ..||... .|||.||.|.|..| ...||...||||.|..|. |.|..|..|.|...|..||. ...|.| ..||||||||||... |.| WSIGGCGNFGRVKKCHKNNCIINIKMVDICHIKIINKCDFNEVNNWRHEKIINKKMRHPCIVKYYGACYCCDNNNDNHYIYMEYIEGEIPISFVKTNNML KTKKQGRFKESRIISMIADLVETLSFLHKH-HVIHRDIKTANLVLDKNK--------------------------NLKLIDFGASTIQ----NKKQFEQY |..|. ||.|..|...|.|||.||...||. |.||||||. | .||... |.||||||.|... |......| KKHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNY LNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNNNDLNGSGSGISTYLNEQYKQSSFAIIGTFNYMAPEVKRNYR--ATRKSDVWSLGCT .|...|||||.|||||||||||||||||||.|||...|||. .|.|.||||....|.||..|||||.|.|.. |.||||.|||||| NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNN--------------IYSNKQYKQKCYSICGTIHYMAPEIKLNNQCCACRKSDIWSLGCT IIEMAGGD---LSQKLN-------------GIPIIPDHLSDTLKDFLNHCLVIDPKKRSYMEELL ..||.||. ..|..| .||.||||.|...|.|..||..|||..|..|.||. VWEMVGGNLCHCEQDINEMAFMVNDNKQNIWIPQIPDHVSNFCKNFIQHCWQIDPNHRWDMHELI |
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| Kinase | ZakA.AA | STE | 9-317 | 23 | 3e-79 | 269.57 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 9-317 Range on HMM: 1-359/359 Sequence Identity: 23% (96 aa) WEEISFIGEGQYG-RVIKCRKKNGFIL--------NEQVDYVAIKIIS----------------KDKFKRNETDILEKIRLFNIP--------RYYSHAE || |..||.| .| . ....||..| .|.....|||... ..|.. .. .||. |.. . .|| . . WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF DD-------NFIYIYMEYIEGENLANILK---TKKQ---------GRFKESRIISMIADLVET-LSFLHKHHVIHRDIKTANLVLDKNKNLKLIDFGAST .. . ..|.|||..| | |.| ... .||.|| |. .. .... |..||.||.|||||| || | ||.||| .. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG IQNKKQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNNNDLNGSGSGISTYLNEQYKQSSFAIIGTFNYMAPEVKRNYR----- . ... .. . . || . ... | | .| . ..|| .||||| .. . QLTDSMANI-Q-S---NN-I-IDC---------------------------------------I-----ETMQQKRNTFVGTP-WMAPEVIQQNGQGRDK -ATRKSDVWSLGCTIIEMAGGDLS----QKL-----------------------NGIPIIPD-------------------HLSDTLKDFLNHCLVIDPK ..|.|.||||||||||| | . . ...| .|| ..|. .|||.|.||..||. GYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPN KRSYMEELLS--HKLI || ..||. |. | KRPTASQLLKSEHPFI |
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| Kinase | ZakA.AA | S_TKc | 9-317 | 24 | 4.2e-63 | 216.87 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 9-317
Range on HMM: 1-231/231
Sequence Identity: 24% (80 aa)
WEEISFIGEGQYGRVIKCRKKNGFILNEQVDYVAIKIISKDKFKRNETDILEKIRLFNIPRYYSHAEDDNFIYIYMEYIEG--ENLANILKTKKQGR---
.| . ||.| .|.| |||.|. .||||||. . |.| .||.| . || ..| . .| ...|. |||..| .| ..| .. ..
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF
-FKESRIISMIADLVETLSFLHKHHVIHRDIKTANLVLDKNKNLKLIDFGASTIQNKKQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNN
| | .. .... ... | ..|.|..||||.| .|. ||. ..|..||| ...
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------------------------------
INNINNNNDLNGSGSGISTYLNEQYKQSSFAIIGTFNYMAPEVKRNYRATR-KSDVWSLGCTIIEMAGGDL----SQKLNGIPIIPDHLSDTLKDFLNHC
..|| .|||||| .. |.|.||.||...||. | |.. . |. .|||...|
-----------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-----SPEAKDFIRKC
LVIDPKKRSYMEELLS-------HKLI
|. ||.|| |.| | .
LQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | ZakA.AA | Ciliate-E2 | 9-317 | 18 | 2e-43 | 146.95 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 9-317
Range on HMM: 1-365/365
Sequence Identity: 18% (81 aa)
WEEISFIGEGQYGRVIKCRK-KNGFILN----------------EQVDYVAIKIISKD--KFKRNETDILEKIR-----LFN------------IPRYYS
. | ||.|..| | ||.. |.. . .. ..|.||..|. ... .| .|. .|. . | | ..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE
HAE--DDNFIYIYMEYIEGENLANILK---TK-------KQGRFKESRIISMIADLVE---------------TLSFLHKHH-VIHRDIKTANLVLDKNK
. . ||| ||. |||..| .| ..| .| . ..|.| |. ... ... | .||. . .|||||| |...
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----
NLKLIDFGASTIQNKK---------------------------QFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNNNDLNGSGS
.|.|||| |...... |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQ--------------------------------------------------------
GISTYLNEQYKQSSFAIIGTFNYMAPEVKR---------NYRATRKSDVWSLGCTIIEMAGGDL---SQKLNGIPIIP------------------DHLS
. . |.|| .|||||. . . . |.|.||||... || | . |.... .| ...|
-------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWS
DTLKDFLNH----CLVIDPKKRSY-MEELLSHKLI
. ||... .|. ||.|| .|..| |. .
QECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | ZakA.AA | CAMK | 14-262 | 17 | 2e-42 | 134.06 | In-house | 1-322 (425) | Show / Hide |
Range on Protein: 14-262
Range on HMM: 1-322/425
Sequence Identity: 17% (66 aa)
FIGEGQYGRVIKCRKK-NG-------FILNEQVDYVAIKIISKD---------------------------------KFKRNETDILEK-------IRLF
.|.|..| | .|. | .. ... ||||||.|. |. |.| .|. | ..
TLGRGSFGKVKLCIHKNTTGKERVHHI-YTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHP
NIPRYYSHAED-------------------DNFIYIYM---EYIEGE----NLANILKTKKQ-------------GRFKESRIISMIADLVETLSFLHKH
|| . | . || |...|. | ||..| | . .. ... |||.|. .. ... . ..|.|
NIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH
HVIHRDIKTANLVLDKNK-----------------NLKLIDFGASTIQNKKQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNN
...|||.| |. ||.|. |.|.|||| ... .... . .... ... .|
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------------------------------
NDLNGSGSGISTYLNEQ-----YKQSSFAIIGTFNYMA-PEVKRNYR--------------ATRKSDVWSLGC
| . | || ||| ||| . . ..|.|.||.|.
----------------QWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGV
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| Kinase | ZakA.AA | Ciliate-E2-Unclassified | 9-267 | 21 | 8.4e-34 | 114.63 | In-house | 1-263 (352) | Show / Hide |
Range on Protein: 9-267 Range on HMM: 1-263/352 Sequence Identity: 21% (69 aa) WEEISFIGEGQYGRVIKCRKKN------------------GFILNEQVDYVAIKIISKDKFKRNETD--------ILEKIRLFNIPRYYSHAEDDNFIYI . | ||.|..| | ||..|. |.|.. ... .... . | | . . || . .| ... . .|.. ||| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI YMEYIEGENLANILKTKKQ---------------GRFKESRII-----SMIADLVETLSFLHKHH-VIHRDIKTANLVLDKNK---NLKLIDFGASTIQN |||.|| .| ...| .|. .| | .. ..| ... |..||. . .|||||| |...|.|. ..|.|||| | .. VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ KKQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNNNDLNGSGSGISTYLNEQYKQS----SFAIIGTFNYM----APEVK-R-N . . .. | . .... . ..|| ||| |||| . | QNNNCD-TNQ------------------------------------------------------Q-QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQN YRAT--RKSDVWSLGCTIIEM | . |.|.||||. . || YDHSKAYKCDIWSLGVILYEM |
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| Kinase | ZakA.AA | TKL | 15-315 | 14 | 2.4e-30 | 106.48 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 15-315
Range on HMM: 1-364/364
Sequence Identity: 14% (63 aa)
IGEGQYGRVIKCRKKN----GFILNEQVDY------VAIKIISKD--------------------------------KFKRNETDILEKIRLFNIPRYYS
||.| .| | | . .. . ||.|..... .|...|. .. ..| || ...
IGSGGFGEVYKGKWRGWGGKC--------PSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMG
HAEDDNF-------------IYIYMEYIEGENLANILKTKKQGRFKESRIISMIADLVETLSFLHKHH--------VIHRDIKTANLVLDKNKN------
. . .. ..| |||..| .| ..| ....... | ...|| .. .||||.|..|. .|.| .
YCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYM
--------LKLIDFGASTIQNKKQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNNNDLNGSGSGISTYLNEQYKQSSFAIIGT
.|. ||| |. .... . |... . . . .... . ..||
YNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMME-SA---------------------------------------------E-HQ-NNRKTTMTQCGT
FNYMAPEV---------K-------RNYRATRKSDVWSLGCTIIEMAGGDLSQK-LNGI---------------------PIIP------------DHLS
...||||| | ... .. |.||.| | . |.. . . . .. . | || ..
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP
DTLKDFLNHCLVIDPKKRSYMEELLSHK
. .|. . .| ||.|| ..|.|..
PSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | ZakA.AA | Pkinase | 9-154 | 29 | 1e-28 | 102.65 | Pfam | 1-159 (293) | Show / Hide |
Range on Protein: 9-154 Range on HMM: 1-159/293 Sequence Identity: 29% (49 aa) WEEISFIGEGQYGRVIKCRKKNGFILNEQVDYVAIKIISKDKFKR---------NETDILEKIRLFNIPRYYSHAEDDNFIYIYMEYIEGE----NLANI .. .. ||.| .|.| ||..|. . ||.|||.|.. | .| |. ... || |.| ||.. ||. ||| || |. . YHIGRKIGSGSFGCVYKCHHKGTGK------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY LKTKKQGRF--KESRIISMIADLVETLSFLHKHHVIHRDIKTANLVLDKNKNL----KLIDFGAS ..|...|.| | ..... ... | ..|.. .||||.| .|. .|.| .. |..||| . ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA |
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| Kinase | ZakA.AA | Pkinase | 236-317 | 29 | 1.6e-17 | 63.08 | Pfam | 173-293 (293) | Show / Hide |
Range on Protein: 236-317 Range on HMM: 173-293/293 Sequence Identity: 29% (36 aa) GTFNYMAPEVKR-NYRATRKSDVWSLGCTIIEMAGG-------------DLSQKLNGIPIIPDHLS-------------------------DTLKDFLNH || .|||||| | . ..|.|.||.||...||. | | |... | | | . ...|||.. GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW CLVIDPKKRSYMEELLSHKLI || ||||| |..| |. . CLCKDPKKRPTAEQILQHPWF |
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| Kinase | ZakA.AA | TKL-Unique | 41-159 | 24 | 4.4e-12 | 39.08 | In-house | 23-169 (290) | Show / Hide |
Range on Protein: 41-159 Range on HMM: 23-169/290 Sequence Identity: 24% (36 aa) VAIKIISK------DKFK--RNETDILEKIR-LFNIPRYYSHAE----DDNFIYIYMEYIEGENLANILKT--------KKQGRFKESRIISMIADLVET ||||.... .. . .|| ...|.. || .|. . . .| |||..| .| . | . .. . .....|. | . VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQG LSFLHKHH--VIHRDIKTANLVLDKN-----KNLKLIDFGASTIQNK . .|| .||||.|. |. .| | | |..||| |....| MYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSK |
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| Kinase | ZakA.AA | MLK | 9-159 | 20 | 2.1e-10 | 32.45 | In-house | 1-186 (291) | Show / Hide |
Range on Protein: 9-159 Range on HMM: 1-186/291 Sequence Identity: 20% (39 aa) WEEISFIGEGQYGRVIKCRKKNGFILNE-QVDYVAIKIIS--------K---DKFKRNETDILEKIRLFN-----IPRYYSHAEDDNFIYIYMEYIEGEN .. .||.| .| | | | . .. . ||.|.. . .. .. | .| ... | |. |. ... . .| |||.|| IQFHEWIGSGSFGKVWKGR----WRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGS LANILKTKKQ------------GRFKESRIISMIADLVETLSFLHKHH---VIHRDIKTANLVLD------KNKNLKLIDFGAST-IQNK |.|.|.... .. . . ... . . ...||.. .||||.| |...| ....|| |||.|. .... LYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQM |
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| Kinase | ZakA.AA | Ciliate-E2-Unclassified | 282-317 | 37 | 3.6e-09 | 27.97 | In-house | 313-352 (352) | Show / Hide |
Range on Protein: 282-317 Range on HMM: 313-352/352 Sequence Identity: 37% (15 aa) IPDHLSDTLKDFLN----HCLVIDPKKRSYMEELLSHKLI ||.|.|.. |||.| .|. .|.|| .|..| | .. IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | ZakA.AA | CAMK | 283-317 | 31 | 1.3e-08 | 23.08 | In-house | 392-425 (425) | Show / Hide |
Range on Protein: 283-317 Range on HMM: 392-425/425 Sequence Identity: 31% (11 aa) PDHLSDTLKDFLNHCLVIDPKKRSYMEELLSHKLI . ..|. ||.....|. ||.|| |. |.|. . H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | ZakA.AA | TKL-Unique | 235-316 | 27 | 3.4e-08 | 25.17 | In-house | 187-290 (290) | Show / Hide |
Range on Protein: 235-316 Range on HMM: 187-290/290 Sequence Identity: 27% (29 aa) IGTFNYMAPEVKRN--YRATRKSDVWSLGCTIIEMAGGDL-------SQKLNGI--------------PIIPDHLSDTLKDFLNHCLVIDPKKRSYMEEL .|.|..||||| |. . ..||||.| | .|.| ... |... . | ||.|. ..| .. | || .| . .| CGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEI LSHKL . |.| I-HRL |
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| Kinase | ZakA.AA | MLK | 235-259 | 46 | 3e-06 | 17.87 | In-house | 194-221 (291) | Show / Hide |
Range on Protein: 235-259 Range on HMM: 194-221/291 Sequence Identity: 46% (13 aa) IGTFNYMAPEV---KRNYRATRKSDVWS .||. .||||| .|. . ..|.|||| AGTYAWMAPEVIQQFRCEKYSEKCDVWS |
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| Kinase | ZakA.AA | Pkinase_Tyr | 15-152 | 24 | 6e-06 | 20.83 | Pfam | 7-156 (270) | Show / Hide |
Range on Protein: 15-152 Range on HMM: 7-156/270 Sequence Identity: 24% (38 aa) IGEGQYGRVIKCRKKNGFILNEQVDYVAIKII------S---KDKFKRNETDILEKI-RLFNIPRYYSHAE-DDNF--IYIYMEYIEGENLANILKTK-- .|||..|.| |.. | .. ||.|.. . ...| | | |. .. . || |.| .. ||| ||| .. .| . |... LGEGAFGEVYKGTWKG--DPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRE KQGRFKESRIISMIADLVETLSFLHKHHVIHRDIKTANLVLDKNKNLKLIDFG ..... .....| .. . ...|. .. ||||. . | ...|. | ||| DKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG |
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| Kinase | ZakA.AA | Pkinase_Tyr | 241-267 | 48 | 0.000498 | 14.27 | Pfam | 181-207 (270) | Show / Hide |
Range on Protein: 241-267 Range on HMM: 181-207/270 Sequence Identity: 48% (13 aa) MAPEVKRNYRATRKSDVWSLGCTIIEM ||||. .... | |||||| | .. |. MAPECINYGKFTTKSDVWSFGVLMWEI |
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| Kinase | ZakA.AA | CZAK | 235-261 | 40 | 0.051056 | 3.31 | In-house | 207-233 (279) | Show / Hide |
Range on Protein: 235-261 Range on HMM: 207-233/279 Sequence Identity: 40% (11 aa) IGTFNYMAPEVKRNYRATRKSDVWSLG .| .||||. | |.|| | | MGCLCWMAPECFKGENYTEKVDVYSFG |
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| Kinase | ZakA.AA | MLK | 282-315 | 26 | 0.075206 | 2.36 | In-house | 258-291 (291) | Show / Hide |
Range on Protein: 282-315 Range on HMM: 258-291/291 Sequence Identity: 26% (9 aa) IPDHLSDTLKDFLNHCLVIDPKKRSYMEELLSHK || .. .| ... | ||.|| . . ..| IPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | ZakA.AA | TKL-Unique | 12-25 | 57 | 0.226245 | 0.82 | In-house | 2-15 (290) | Show / Hide |
Range on Protein: 12-25 Range on HMM: 2-15/290 Sequence Identity: 57% (8 aa) ISFIGEGQYGRVIK .. |||| ||.|.| WNKIGEGGYGQVYK |
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| Kinase | ZakA.AA | NZAK | 378-649 | 48 | 2.3e-183 | 615.45 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 378-649 Range on HMM: 1-329/329 Sequence Identity: 48% (159 aa) FDKDDSEGGAGNFGDVKKGLLNETEVAIKFVKKAHCEAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLMNNHKVL .. .. ||...|..|||.....||.|...|.|.||..||.||.||||..||...||.||.....||||..|....|||..|||.||||||||||..|.| WEEISFIGGCQFFSRVKKCRKKNTEIANEQVDKVHCKIITKCDFFYHETDILEKIRHFNIPRYYSACIKHAEDDNYHCIYMEWMEGGNLTQFLMNDKKQL ENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREILPN--------QLYGS----------------------------------NEFTAK ....|...|...|||....||||.||||||..||||.|||....... |.|.. ||.... RFKEHRIIKMIADIAETMSYLHKHHIIHRDIKSNNVILDFNKNLKLIDFGSSIIQQQYQFEQYLNETTNNNNNPNNNNNNNNNNNNNNNNNNNNNENNNN VCDFG---------------LSSNQSESKKLRGGSIHYMAPENLNGSPINEKSDIYSFGLLVWQMFSYAPPNTIYSPKEMASMVSDPKQNYRPQIPFNVP .|||| |||||.|||...||..|||||||.|...||||||..|||..|||||.|.|||||||||||||||||.|.||.|||||.|| ICDFGNNNDLNGSGSGISTYLSSNQKESKFAIGGTHHYMAPENKNNHRINEKSDVWSFGCTVWQMFGYNPPNTIYSPKEMASMVSDQKFNYIPQIPFHVP LKFKELITQCWDRNPLNRPKDFSIIIEKL .|.|..||||||..|..||||||..|||| DKMKDFITQCWDIDPKKRPKDFSHMIEKL |
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| Kinase | ZakA.AA | Dicty3 | 382-645 | 29 | 2.5e-140 | 466.23 | In-house | 1-351 (351) | Show / Hide |
Range on Protein: 382-645
Range on HMM: 1-351/351
Sequence Identity: 29% (105 aa)
DSEGGAGNFGDVKKGLLNETEVAIKFVKKAHCEAITVCDTF-----YHEVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQF-----LM
.| ||.||||.|||. .|.....||.|...|.. |..||.. .||..|....|||.||....||........||.|..|...|.....| ..
WSIGGCGNFGRVKKCHKNNCIINIKMVDICHIKIINKCDFNEVNNWRHEKIINKKMRHPCIVKYYGACYCCDNNNDNHYIYMEYIEGEIPISFVKTNNML
NNHKVLENNPHLRVKLLTDIAKGILYLHKQ-HIIHRDLTSNNVLLDFKREILPN-------------QLYGSNEFTAKVCDFGLSSNQS-----------
..|| ...|.|...|...|..|...|.||. ||||||....|..||.......| |.|.|||...|..|||||.|.|
KKHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNISYYSNNNNNNNY
-------------------------------------------------ESKKLRGGSIHYMAPENLNGSPIN--EKSDIYSFGLLVWQMFSYAPPNTIY
.......|.|||||||........ .||||.|.|..||.|..........
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNVKIINNNIYSNKQYKQKCYSICGTIHYMAPEIKLNNQCCACRKSDIWSLGCTVWEMVGGNLCHCEQ
SPKEMASMVSDPKQN-YRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSII
...|||.||.|.||| ..||||..|....|..|..||...|..|......|
DINEMAFMVNDNKQNIWIPQIPDHVSNFCKNFIQHCWQIDPNHRWDMHELI
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| Kinase | ZakA.AA | TKL | 386-649 | 24 | 3.6e-72 | 246.08 | In-house | 2-364 (364) | Show / Hide |
Range on Protein: 386-649
Range on HMM: 2-364/364
Sequence Identity: 24% (93 aa)
GAGNFGDVKKGLLNE----------TEVAIKFVKKAHC------------------------EAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGE--
| | || | || .. ..||.| |. .. || .... |....|.||||||||||..|. .
GSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGC
-------KETNHCIVSEWMSGGN-LTQFLMNNHKVLENNPHLRVKLLTDIAKGILYLHKQH--------IIHRDLTSNNVLLD-----FKREILPNQLYG
....||| |...||. | ... .|.|... |||.|. ||| .. ||||||.|.|.|.| .. .
VCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYM---YNP
SNEFTAKVCDFGLSSNQSES----------------------KKLRGGSIHYMAPENLNGS----------------PINEKSDIYSFGLLVWQMFSYAP
.. ..|.|||||| . |.| . ..|.. .|||| |.|. . .||.|.||||.. | ... .
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR
PNT-IYSPKEM------ASMVSDPKQNYRPQIP------------FNVPLKFKELITQCWDRNPLNRPKDFSIIIEKL
| . .. .. . .. . . ..|| || ..| .|.|...||| .| .|| |. |...|
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS-FQEILKRL
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| Kinase | ZakA.AA | TKL-Unique | 386-649 | 34 | 1.1e-69 | 237.87 | In-house | 6-290 (290) | Show / Hide |
Range on Protein: 386-649 Range on HMM: 6-290/290 Sequence Identity: 34% (101 aa) GAGNFGDVKKGLLNETEVAIKFVKKAHCEAI-TVCDTFYHEVLILSNLR-HPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLM-------NNHKV |.| .| |.|| . ..|||| .. . .. ..|. || ....|. |||||..|..|.. .. | |||.| ..||.| | || . GEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNN LENNPHLRVKLLTDIAKGILYLHKQH--IIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSSNQSES--KKLRG----------GSIHYMAPE ...|. .|||. |||.| ||| ||||||.| |.|.| . | .|. .|.|||||| ..| . ..... ||. .|||| CKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNI--------AEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE NLNG--SPINEKSDIYSFGLLVWQMFSYAP------PNTIYSPKEMASMVSDPKQNYRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSIIIEKL |.. . ..||||.|||| .| ... | ..... ..|| . . |||| || . | ...||.|||...| .|| |. ||..| VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPS-FDEIIHRL |
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| Kinase | ZakA.AA | CZAK | 376-649 | 35 | 1.5e-63 | 217.47 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 376-649
Range on HMM: 1-279/279
Sequence Identity: 35% (102 aa)
LEFDKDDSEGGAGNFGDVKKGLLNETEVAIKFVKKAHCEAITVC---DTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLMN
|.| . . | | || |.|. .. |||| . . . | || |.| |.|||.|||. || |. |||| ||| || | ..|
LKFGQ---TIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGP--NHHCIVMEWMGGGSLRRLLTD
NHKVLENNPHLRVKLLTDIAKGILYLHK--QH--IIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLS---SNQSESKKLRGGSIHYMAPENLN
.. ||||. .. |||.| ||| |.||||.| |.||| . .|. ||||| | |.. .||||
HYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFK
GSPINEKSDIYSFGLLVWQMFSYAPPNTIYSPKEMASMVSDPKQNYRPQIPFNVPLKFK---ELITQCWDRNPLNRPKDFSIIIEKL
| ||.|.||||...| . |. | || . |||| .| . . | |||..||. || || |. |.. |
GENYTEKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAA--YENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPS-FKQILQHL
|
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| Kinase | ZakA.AA | STE | 380-640 | 19 | 2e-61 | 210.35 | In-house | 1-347 (359) | Show / Hide |
Range on Protein: 380-640 Range on HMM: 1-347/359 Sequence Identity: 19% (70 aa) KDD-SEGGAGNFGDVKKGLLN------ETE-----------VAIKFVKKAHCEA--------------ITVCDTFYHEVLILSNLR--HPNIVQFMAACI .. .. | |.|| | |.. . .| .||| ... .|.. .. . . .|. |..... |||||.. ... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF KYGEK---ETNHCIVSEWMSGGNLTQFLMNNHKVLENNP-----------HLRVKLLTDIAKG-ILYLHKQHIIHRDLTSNNVLLDFKREILPNQLYGSN | |.. ... .|. |.|.|| |.... .......... .. . . .| || |||..||||||. . |.|| KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------------- EFTAKVCDFGLSSNQSE-------------------SKKLRGGSIHYMAPENLNG------SPINEKSDIYSFGLLVWQMFSYAPPNTIYSPKEMASMVS .| ||||.... .. . |. .|||| ... .. ..|.||.|.|.... | || ..| .. | ---VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIP DPKQNYR------------PQIPF-------------------NVPLKFKELITQCWDRNPLNRPK . . .. |..| .. .||. | .| ...| .||. FNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT |
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| Kinase | ZakA.AA | Pkinase_Tyr | 386-649 | 30 | 4.5e-50 | 170.22 | Pfam | 8-270 (270) | Show / Hide |
Range on Protein: 386-649 Range on HMM: 8-270/270 Sequence Identity: 30% (88 aa) GAGNFGDVKKGLLN------ETEVAIKFVKKAHCEAIT-VCDTFYHEVLILSNL-RHPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLMNN--HK |.|.||.|.|| .. ...||.| . | .. . | .|. |...| .|||||.....|.. || ...|| | | .|.| .| .. | GEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLRKHREDK VLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSSNQ-------SESKKLRGGSIHYMAPENLNGSP . .. .. ..|||| ||. ...||||| |.|.. .....|.|||||. ... . | |||| .| . QPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT-------------ENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK INEKSDIYSFGLLVWQMFSYA-PPNT---IYSPKEMASMV-SDPKQNYRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSIIIEKL ..|||..||| | | .|.| | | . |. |. .. | .|| .| | | . .|..|||. .| .|| || |.|.| FTTKSDVWSFGVLMWEIFTYGEQP-TYPGM-SNEEVYEYIYED---GYRMPCPENCPDEIYDLMKQCWHYDPEDRP-TFSEIHEQL |
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| Kinase | ZakA.AA | MLK | 386-649 | 28 | 5.8e-49 | 167.99 | In-house | 8-291 (291) | Show / Hide |
Range on Protein: 386-649 Range on HMM: 8-291/291 Sequence Identity: 28% (86 aa) GAGNFGDVKKGLLNETE-----VAIKFVK--KAHCEAITV--CDTFYHEVLILSNLRHPN----IVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLMN |.| ||.| || .. ||.| |. . . ..| . | |. .|. |.||| |.||...|.... . |||.|...|| | .| . GSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSLYNVLHG NHKVLE-----------NNPHLRVKLLTDIAKGILYLHKQH---IIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSSNQSES---KKLRGGS . . . ... .. ...|.|. |||.. |||||| | |.|.| . .. |.|.||||.| ... . . |. ARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDE-IC-----H-DMHHGTLKICDFGTSRDWHQMCTNMMSNAGT IHYMAPENL---NGSPINEKSDIYSFGLLVWQMFSYAPPNT-IYSPKEMASMVSDPKQNYRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSIIIEKL .|||| . ... .||.|..|.|.. |.|.. | .|.| . | .| .. || || . | .|.|..|||. .| .||. |. |...| YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGL--RPPIPSTCPEHWKKLMKQCWNQDPHKRPS-FRQIVQHL |
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| Kinase | ZakA.AA | TyrKc | 379-649 | 27 | 3.4e-43 | 150.73 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 379-649 Range on HMM: 1-280/280 Sequence Identity: 27% (83 aa) DKDDSEGGAGNFGDVKKGLLNETEVAIKFVKKAHCEAITVCDTFYHEVLILSNL--RHPNIVQFMAACIKYGEKE---TNHCIVSEWMSGGNLTQFLMNN . . . | |.|| | || .. ..||.| .|. . |..| |...| .|||||.. ..|.. |.. ..|| | |..|.| ..| .. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH HKVLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSSNQSES----------KK-----LRG-GSIH .. .. .. ..||.| |||....||||| |.|.. .. |.|..||||| . . .| .. | RPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR YMAPENLNGSPINEKSDIYSFGLLVWQMFSYAPPNTIYSP-----KEMASMVSDPKQNYRPQIPFN--------VPLKFKELITQCWDRNPLNRPKDFSI |||| .| . ..|||..||| . | .|.| . |. .. . .. . || ||. .| | | . ....|||...| .|| || WMAPECINYGKFTTKSDVWSFGVCMWEIFTYG--QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSE IIEKL |.|.. IHECF |
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| Kinase | ZakA.AA | Pkinase | 386-639 | 22 | 4e-41 | 146.49 | Pfam | 8-282 (293) | Show / Hide |
Range on Protein: 386-639 Range on HMM: 8-282/293 Sequence Identity: 22% (67 aa) GAGNFGDVKKGLLNETE--VAIKFVKKAHCEAITVCDTFYH--EVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSGG----NLTQFLM--NNHK |.|.|| |.|. |. ||.| .|| | .. | . |. |. .|.|||||.. .. ... ..| |.. || | ... .. . GSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYISTWRHGC VLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLS----SNQSESKKLRGGSIHYMAPENLN-GSPIN .. .. . .. |..|. |.|.. |||||| . |.|.| .. .. . |.|||||. .. . . |...||||| .. |... FY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA--------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG EKSDIYSFGLLVWQMFS-YAPPNTI-----YSPKEMASMVSDPKQNYRPQIPFNVP-----------------LKFKELITQCWDRNPLNRP |.|..|.|.....|.. . | .....| .. .|. . . . ... .|..|. |....| || PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP |
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| Kinase | ZakA.AA | S_TKc | 379-650 | 22 | 2.2e-40 | 141.43 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 379-650 Range on HMM: 1-231/231 Sequence Identity: 22% (64 aa) DKDDSEGGAGNFGDVKKGLLNE--TEVAIKFVKKAHCEAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSG--GNLTQFLMNNH . . | | || |.|. .. .|||| .| .... |. ||.. .|||||.. .. .. ..| | ..| |.| ... .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRG KVLEN---NPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNGSPINE . . .. ... |.... |.|...|||||| |.||| . |.|||||. . |. .||||| | . . RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGK -KSDIYSFGLLVWQMFSYAPPNTIYSPKEMASMVSDPKQNYRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSIII-------EKLK |.|..|.| ... |.. || ...| .. . .|..| .|....| .|| . CKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | ZakA.AA | CAMK | 386-579 | 16 | 1.4e-37 | 118.17 | In-house | 3-321 (425) | Show / Hide |
Range on Protein: 386-579
Range on HMM: 3-321/425
Sequence Identity: 16% (55 aa)
GAGNFGDVKKGLLNETE--------------VAIKFVKKAHCE-------------------------AITVCDTFYHEVLILSN-------LRHPNIVQ
| |.|| ||.. .| ||||...| .. ...|. |... |.||||..
GRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIK
FMAACI----------------KYGEKETNHCIVS---EWMSGG----NLTQFLMNNHK---------VLENNPHL----RVKLLTDIAKGILYLHKQHI
. . . .|... ..| | .||| | ... . . .. .. .. .. |. .. |.|...|
LYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDLTSNNVLLDFKREILPNQLYGSNE-------FTAKVCDFGLSSNQSESKKLR--------------------------GGSIHYMA-PENLNG---
.|||| |.||| . . .. . . . .. |..|||.. ...... |. .||| || |||
VHRDLKPENILLDDNNDDSDP-V-E-HDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH
-----------SPINEKSDIYSFG
....|.|. | |
CNMQNATDEEKPYYGPKCDMWSCG
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| Kinase | ZakA.AA | Ciliate-E2 | 428-639 | 19 | 1.4e-31 | 105.69 | In-house | 85-353 (365) | Show / Hide |
Range on Protein: 428-639
Range on HMM: 85-353/365
Sequence Identity: 19% (57 aa)
ILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLMNN-HKVLENNP-------HLRVKLLTDIAK---------------GILYLHKQH-I
||..| ||||... . . ....| .| | .||.| ... || .| ... . . .. . |.. .. |||... |
ILEQLNHPNIIKMYECFQE--KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNI
IHRDLTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSSNQSES------KKLRG----------------------------GSIHYMAPENLNGSP-
||||. .|.|. |..||||| ..... |.... |. .|||||.||| .
IHRDIKPENILF------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKY
--------INEKSDIYSFGLLVWQMFSYAPPNTIYSPKEMASMVSDPKQNYRPQ--------------IPFNVPLKFKELITQ----CWDRNPLNRP
..|.||.|.| . .| . || . | ..... ........ | || . . ...| .|.
DNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI
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| Kinase | ZakA.AA | Ciliate-E2-Unclassified | 428-585 | 23 | 1.4e-21 | 71.67 | In-house | 74-263 (352) | Show / Hide |
Range on Protein: 428-585 Range on HMM: 74-263/352 Sequence Identity: 23% (49 aa) ILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMSGGNLTQFLMNNHK---------------VLENNPHLRV----KLLTDIAKGILYLHKQH-IIHRD ||.|. ||.|| .. . ... | .|| | . ||.| |.. ...| . .. ... | .|. |||... ||||| ILLNHPHPFIVK----MFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRD LTSNNVLLDFKREILPNQLYGSNEFTAKVCDFGLSS-----NQSESKKL--------------RGGSIHYM----APENLNGSPIN----EKSDIYSFGL .. .|.|.| . . . |..|||.|. |... .. . |.. || ||| | | . .|.||.|.| IKPENILFDNNGK----------NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGV LVWQM . .| ILYEM |
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