Gene 7TMK1 (Slime mold)

7TMK1

Species: Slime mold
Alias: DdisK193, DDB0229939, 7TMK1
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: CZAK

Sequence

Name Sequence Type Origin Length Description Download
7TMK1.AA Protein None 691 None Fasta, JSON
7TMK1.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of 7TMK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7TMK1.AA CZAK 363-623 67 6.4e-225 753.51 In-house 1-279 (279) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-279/279
Sequence Identity: 67% (187 aa)

FKFGQVIGEGYFGEVRKAVWKGAVVAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCSETN--LNGIVTEYMGGGSLDRLLTDRYFLI
.||||.||.|.||||.||.|.|..||.||.|||.|||.|.|||||.|.|||.|.|.|.|||..||||.|||..  ...||.|.||||||.|||||.||..
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

KQNPILAWNMAISIARGMFYLHD-WKPNPILHRDLSTKNILLDESLT------------IAKVADFGLS---KEQGFEMTSTVGHLCYQAPEVFIGELYT
||||.|.|||||.|||||.|||| ||||||||||||..|||||.|.|            |.|..|||||   .||.||||.|.|.||..|||.|.||.||
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

PKADVYSFGLLVWCIITGEQPNQNLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
.|.||||||...|||||..||.||.||.|||||||||||||||||||||||.|||.||||||.|.|.|||||..||..|
EKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase 7TMK1.AA TKL 369-623 27 4.1e-99 335.59 In-house 1-364 (364) Show / Hide 
Range on Protein: 369-623
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)

IGEGYFGEVRKAVWKG----------AVVAVKILHRNSFRNTDGNKEE-------------------NVFLKEVAILSILR--HPNVLQFLGVCSETNL-
||.| |||| |..|.|           .||||......  ... | .|                   . | .|. |....|  |||..||.|.| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------NGIVTEYMGGGS-LDRLLTDRYFLIKQNPILAWNMAISIARGMFYLHDWKP-----NPILHRDLSTKNILLDESLT------------
             .||.||. ||| |..|.          . .  ..|..||||| ||| ..|      ||.|||| .||||.|| .|            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

-IAKVADFGLSKEQ----GFEMTS------------------TVGHLCYQAPEVFIGE----------------LYTPKADVYSFGLLVWCIITGEQPNQ
  .|..|||||..     . ..|.                   .|.... ||||. |.                 |..|.||||||.. | |.|...| .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

NLQPLKMA---------HLAAYENYRPPMP---------QPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
.. .  |           .......|||.|         .| ..... . ||...||.  ||.||||. ||. |
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 7TMK1.AA MLK 363-623 35 6.1e-76 258.61 In-house 1-291 (291) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-291/291
Sequence Identity: 35% (103 aa)

FKFGQVIGEGYFGEVRKAVWKGAV-----VAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPN----VLQFLGVCSETNLN-GIVTEYMGGGSLDRL
..| ..||.| ||.| |..|..       ||||. . . |   |   |   | .|. .|.||.|||    . ||.|||.... . .||.||. |||| ..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LTDRYFLIK-----------QNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDE-----SLTIAKVADFGLSKEQGFE---MTSTVGHLCYQ
| ..   .            . . .| | |  .|||| |||  .| || ||||  .|||.||       ...|..|||.|..       |.|. | . . 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVF---IGELYTPKADVYSFGLLVWCIITGEQPNQ-NLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
||||.    .| |. |.||.|.|.. | ..|.| | .  . |.  |  .||.. |||.|.  .. |.   ||...||.  |..||||. |. .|
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWK---KLMKQCWNQDPHKRPSFRQIVQHL
Kinase 7TMK1.AA TKL-Unique 365-623 34 1.1e-71 244.45 In-house 1-290 (290) Show / Hide 
Range on Protein: 365-623
Range on HMM: 1-290/290
Sequence Identity: 34% (103 aa)

FGQVIGEGYFGEVRKAVWKGAVVAVKILHRNSFRNTDGNKEENV-FLKEVAILSILR-HPNVLQFLGVCS-ETNLNG---IVTEYMGGGSLDRLLTD---
|. .|||| .|.| |..|.|  ||.|..|   . | | ..|.   | .|| ... |. |||.... |.|  ..  ..   ||.||. ||||. .|..   
FWNKIGEGGYGQVYKGKWRGYPVAIKQFH---P-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

----RYFLIKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIA----KVADFGLSKEQGFEMTSTVGHL--------C----YQAP
        .| |. .  .||| ||.|| |||  .|  |.|||| ..|.|.|. ..||    |..|||||| .  ....|.. .        |    . ||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

EVFIG--ELYTPKADVYSFGLLVWCIITGEQ------PNQNLQPLKMAHLAAY--ENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
||. .  ..|. |.||||||  .| |.|...      | |.. . . . ...|  |||||| |. .    ... .||..||.  |..||||. |.  |
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCP---KEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 7TMK1.AA Dicty4 363-625 37 6e-70 232.5 In-house 1-277 (277) Show / Hide 
Range on Protein: 363-625
Range on HMM: 1-277/277
Sequence Identity: 37% (107 aa)

FKFGQVIGEGYFGEVRKAVWKGAVVAVKIL--HRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCS----ETNLNGIVTEYMGGGSLDRLLTD-
 ...| ||.| |||| |. |.|  ||||.|  |   |.     .. | |.|||.|.. .||||...|.| |     .     ||||||  |.| .|| | 
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFD----ENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDK

---RYFLIKQN--PILA-WNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSK------EQGFEMTSTVGHLCYQAPEVFIGELY
       ||     |..   ||...|||| .||   |. |.|||| . |.| |..... ||.|||||.      .... .....|  |. ||||  .. |
PSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLVDKNWRV-KVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY

TPKADVYSFGLLVWCIITGEQPNQ--NLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDF--LEA
. ||||||||.. | | |.. | |     . . . . . .  |||.|.  .| |    .||. || ..|. ||||. |.    ||.
NEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWK---HLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 7TMK1.AA HH498 363-623 33 2.1e-62 196.49 In-house 1-284 (284) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-284/284
Sequence Identity: 33% (98 aa)

FKFGQVIGEGYFGEVRKAVWKGAVVAVKILHRNSFRNTDGNKEE------NVFLKEVAILSILRHPNVLQFLGVCSETNLN-GIVTEYMGGGSLDRLL--
..|   || | ||.| |  | . .||||    . |    . | .        | .|| |.. | ||.| ||.. | .      |||.|  .||| ..|  
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAF----CCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNT

-------------TDRYFLIKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLS--KEQGFE--MTSTVGHLCYQAPE
              ..   . . .     ... .|.|| |||.  . || ||||   |||..|   .|.||||| |  ...  .  ||.  | | . |||
IPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHED-GHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPE

VFI-GELYTPKADVYSFGLLVWCIITGEQPNQNLQPLKMAHLAAYENYRPPMPQP----MDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
||  .  |. |.||.|... .| . |.| |   . |   |   ||   |||.||     ..  | |   || |||   ||.||.|. |.  |
VFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSN---LIQMCWHPCPENRPDFDQIVTIL
Kinase 7TMK1.AA DRK 363-625 38 5.7e-59 198.35 In-house 1-258 (258) Show / Hide 
Range on Protein: 363-625
Range on HMM: 1-258/258
Sequence Identity: 38% (103 aa)

FKFGQVIGEGYFGEVRKAVWKGAVVAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCSETNLNGIVTEYMGGGSLDRLLTDRYFLIKQ
 | |  || | .|||    | |  |||| |      | .  .  | | .|. ... |||||. ||.| | .     |..|||  ||| . | |    |. 
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNH---NINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDES--IEM

NPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSK------EQGFEMTSTVGHLCYQAPEVFIGELYTPKADVYSFGLLV
   |   |.. .|.|| |||   |  |.|||| . | | ||.  . ||||||||       ...| ||  .|  |  ||||   . || |||||||.   
DWPLMKQMMFDCAKGMIYLHCCNPI-IIHRDLKSHNLLVDEHWQV-KVADFGLSTRFKKHKQHKFAMT-MCGTPCWTAPEVLRNQRYTEKADVYSFAIVL

WCIITGEQPNQNLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFLEA
| ..| . | .   ..        .  ||||||   | .    .|.  ||   |  |||.  .|  |||
WECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYI---QLMNDCWNEDPQHRPSMQECLERLEA
Kinase 7TMK1.AA Dicty4-Unclassified 363-623 33 5.6e-57 193.66 In-house 1-263 (263) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-263/263
Sequence Identity: 33% (92 aa)

FKFGQVIGEGYFGEVRKAVWKGAVVAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCSETNLNG--------IVTEYMGGGSLDRLLT
 .  | ||.| | .| | .|||  ||||..  |.|.  .   ..  |.|||.||  . ||| ..  | |    .|         ||.| |  | |  .  
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQD--FKKEVEILGSIQHPNLVKCYGYC----INPRSHKSTMCIVMEFMHKGNLFEVIH

----DRYFLIKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSKE--QGFEMTSTVGHLCYQAPEVFIGELYTPKAD
    ..   || .  |   .|..||.|| .||      . |||.   |||.|    | |.||||.| .    | ||   |     .||.  .| |. |.|
SKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNI-KIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSD

VYSFGLLVWCIITGEQPNQNLQ-PLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
|||.... .  .||. | |  | .. .| . .    || .|   |. |    |||  ||  .|  ||..  | . |
VYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWK---KLIKWCWHNDPNKRPTMNQIIQYL
Kinase 7TMK1.AA TK 363-623 17 6e-55 182.26 In-house 1-486 (486) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-486/486
Sequence Identity: 17% (88 aa)

FKFGQVIGEGYFG---EVRKAVWKGA---------------------------VVAVKILHRN-SFRNTDGNK-EENV------FLKEVAILSILR----
 ..|...||| ||   ||.|. |.|                             ||||.|.   .   ..    | .       ||.|........    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVLQFLGVCSET------------NLNGIVTEYMGGGS----LDRLLT--DRYFLIKQNPI------------------------------------
 |||.....|||..                 ||.||| .|.    |.  |   ...|   |. .                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------------LAWN-------------------MAISIARGMFYLHDWKPNPI------LHRDLSTKNILLDESLT----------IAKVADFGL
                 ..                   |.  ||.|| |||.   ...       |||| . |.|..|...          ..|.|||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHS---KNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

S------------KEQGFEMTSTVGHLC-------------------------YQAPEVFIGEL---------YTPKADVYSFGLLVWCIIT-G-EQPNQ
|            ...    .|. |. .                         . |||.. .           .|.| ||.||| |.| | | | |..  
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYG

NLQPLKMAH-------LAAYEN---------------YRPPMPQPMDP----------MWENLGKL-IEMCWKKSPEERPSFSFILDFL
..   . ..       .   ..               .|.| |. . .          ... .  . . .||.. ||.||.|| ....|
GMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 7TMK1.AA LRRK 363-625 28 4.5e-53 182.64 In-house 1-351 (351) Show / Hide 
Range on Protein: 363-625
Range on HMM: 1-351/351
Sequence Identity: 28% (102 aa)

FKFGQVIGEGYFG-EVRKAVWKG----------------------------AVVAVKILHR----------------NSFRNTDGNKEENV---------
.|... ||.| || .| .| |.|                            . ||.|...|                |.  | ... |            
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

----FLKEVAILSILRHPNVLQFLGVCSETNLNGIVTEYMGGGSLDRLLTDRYFLIKQNPI------LAWNM----AISIARGMFYLHDWKPNPILHRDL
    | .||.|.| |.|||... .|.|   .   .|.||.  |.|...| ..    ||...      . |..    |. ||.|| |||. .| ||.||||
AFREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNK----KQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDL

STKNILLDES-----------LTIAKVADFGLSK-EQGFEMT---STVGHLCYQAPEVFIGE---LYTPKADVYSFGLLVWCIITGE-QPNQNLQPLK--
 . |||| .|            ..||.||||.|   | | |.     ||   ..|||.  ..    || |.|.||||.. | ..|.. .| ....  .  
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHM

--MAHLAA--YENYRPPMPQP-MDP--MWENLGKLIEMCWKKSPEERPSFSFILDFLEA
  | ..     |  ||. ||  . |   |  . .||. ||.  |..||.|| |...|. 
QWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 7TMK1.AA S_TKc 363-623 25 9.2e-49 169.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-231/231
Sequence Identity: 25% (71 aa)

FKFGQVIGEGYFGEVRKAVWKG--AVVAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCSETNLNGIVTEYMGG--GSLDRLLTDRYF
......||.| ||.|.|...|.   .||.||..             . ...|..||.  .|||. ....|. . .   .|.||..|  |.| ... .|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

L---IKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSKEQGFEMTSTVGHLCYQAPEVFIGELYTP-KADVYSFGL
     . ..  |. ..  |.... |.|.   . |.||||   ||||||     |..||||...     |. .| . | ||||.    |.. |.|..|.| 
HGLRFPFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LVWCIITGEQPNQNLQPLKMAHLAAYENYRPPMPQPMDPMWENLGK-LIEMCWKKSPEERPSFSFILD---------FL
...  ..|. | .  |. .| ..                     .| .|. |..| ||.||.   .|          ..
ILYEMLCGYPPFP--QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 7TMK1.AA TyrKc 363-623 28 1.4e-47 165.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-280/280
Sequence Identity: 28% (85 aa)

FKFGQVIGEGYFGEVRKAVWKGAVVAVKILHRNSFRNTDGNKEENVFLKEVAILSIL--RHPNVLQFLGVCSET-------NLNGIVTEYMGGGSLDRLL
 ..|...||| ||||.|..||   |||| |. ..         .  |..|  |.. |  .|||.....|||..            ||.||| .|.|.  |
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-TDRYFLIKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSKEQGFE--------MTST----VGH--LCYQ--APE
   |      ..    .... ||.|| |||.    .. |||| . |.|..| . ..|..|||||.. . .        . ..     |.  | .   |||
RKHRPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

VFIGELYTPKADVYSFGLLVWCIIT-GEQPNQN-----LQPLKMAHLAAYENYRPPMPQPMDP-----MWENLGKLIEMCWKKSPEERPSFSFILDFL
..    .|.| ||.||| . | | | |.||  .     . .  . ..    ...|..| .  |     . . . .....||.  ||.||.|| | ...
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 7TMK1.AA Pkinase 363-623 25 4.6e-46 163.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 363-623
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

FKFGQVIGEGYFGEVRKAVWKGAV--VAVKILHRNSFRNTDGNKEENVFL-KEVAILSILRHPNVLQFLGVC-SETNLNGIVTEYMGGG----SLDRLLT
...|..||.| ||.|.|...||    |||||. .   |... .|... ..  |..|.  |.|||........ .....  .|.||..||    .| ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKK---RHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYIS

--DRYFLIKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIA---KVADFGLSK---EQGFEMTSTVGHLCYQAPEVFI-GELYTP
  ..  ..   .  . ...  |.||. |.|. .   |.||||   |||.|.  .|.   |..||||.|   .   .||. .| . | ||||   |. |.|
TWRHGCFY-FSEWECKFYMYQILRGLEYCHS-M--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGP

KADVYSFGLLVWCIITGEQPNQNL------QPLKMAHLAAYENYRPPMPQPMDPMW----------------ENLGKLIEMCWKKSPEERPSFSFILDF-
|.|..|.|..... ..|. | ..        ...|  .  .  .. . |.. ....                |.. ..|. |..| |..||..  ||   
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

-L
 .
WF
Kinase 7TMK1.AA Pkinase_Tyr 363-517 32 8.4e-42 142.19 Pfam 1-159 (270) Show / Hide 
Range on Protein: 363-517
Range on HMM: 1-159/270
Sequence Identity: 32% (54 aa)

FKFGQVIGEGYFGEVRKAVWK------GAVVAVKILHRNSFRNTDGNKE--ENVFLKEVAILSIL-RHPNVLQFLGVCS-ETNL--NGIVTEYMGGGSLD
 .||...||| ||||.|..||      .  ||||.| ..    .   ..     |..|..|.. | .|||.....|||. .       ||.||| .|.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

RLLTDR-YFLIKQNPILAWNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSK
  | ..     . ..    .|.. ||.|| ||.. .   . |||| ..|.|..|.. ..|..||||..
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENN-VVKICDFGLAR
Kinase 7TMK1.AA Pkinase_Tyr 534-623 36 2.6e-17 59.26 Pfam 182-270 (270) Show / Hide 
Range on Protein: 534-623
Range on HMM: 182-270/270
Sequence Identity: 36% (34 aa)

APEVFIGELYTPKADVYSFGLLVWCIIT-GEQP-NQNLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERPSFSFILDFL
|||..    .| | ||.||| | | |.| ||||  ... .  . .. . ..||  ||.|..  .. . .|. .||.. ||.||.|| |. .|
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPEN-CPDEIYDLMKQCWHYDPEDRPTFSEIHEQL