Gene DDB0214883 (Slime mold)

DDB0214883

Species: Slime mold
Alias: DdisK197, DDB0214883, Rsc21
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Dicty4
Subfamily: DRK

Sequence

Name Sequence Type Origin Length Description Download
DDB0214883.AA Protein None 1288 None Fasta, JSON
DDB0214883.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of DDB0214883.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_TYP DDB0214883.AA LRR_TYP 490-513 41 6e-06 27.07 SMART 1-24 (24) Show / Hide 
Range on Protein: 490-513
Range on HMM: 1-24/24
Sequence Identity: 41% (10 aa)

LTSLKTLDLSFNQITDISPQTNLH
|..|..||||.||.| . |..  .
LPNLRELDLSNNQLTHLPPGAFQG
LRR_TYP DDB0214883.AA LRR_TYP 444-466 41 0.00093 19.73 SMART 1-24 (24) Show / Hide 
Range on Protein: 444-466
Range on HMM: 1-24/24
Sequence Identity: 41% (10 aa)

LVHLKRLRLNHNQLTALPKEL-YS
|..|..|.|..||||.|| ..  .
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 DDB0214883.AA LRR_1 446-467 29 0.001164 17.15 Pfam 1-26 (26) Show / Hide 
Range on Protein: 446-467
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

HLKRLRLNH-N--QLT-ALPKE-LYSL
.|..| |.. |  .||  .|.. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 DDB0214883.AA LRR_1 492-512 40 0.006985 14.39 Pfam 1-26 (26) Show / Hide 
Range on Protein: 492-512
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLKTLDLSF-N--QIT-DISP--QTNL
.|..||||  |  ..| .|.|    ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 DDB0214883.AA LRR_1 469-490 25 0.008488 14.09 Pfam 1-26 (26) Show / Hide 
Range on Protein: 469-490
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RLTTLYLNN-N--NF-KVVPKE-INRL
.|..|.|.. |  |. . .|.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP DDB0214883.AA LRR_TYP 467-489 33 0.012384 15.48 SMART 1-24 (24) Show / Hide 
Range on Protein: 467-489
Range on HMM: 1-24/24
Sequence Identity: 33% (8 aa)

LPRLTTLYLNNNNFKVVPKEI-NR
|| |..|.|.||... .| .. . 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 DDB0214883.AA LRR_1 423-444 33 0.35287 8.35 Pfam 1-26 (26) Show / Hide 
Range on Protein: 423-444
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ELRDLDLSA-N--QL-KKVSKS-IGLL
 |. ||||  |  .| .....| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP DDB0214883.AA LRR_TYP 421-443 37 0.556298 1.94 SMART 1-24 (24) Show / Hide 
Range on Protein: 421-443
Range on HMM: 1-24/24
Sequence Identity: 37% (9 aa)

ILELRDLDLSANQLKKVSKSI-GL
  .|| |||| |||. .   . . 
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 DDB0214883.AA LRR_1 400-422 29 22.209822 1.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 400-422
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

KSTKLSLSNC---WL-KVIPTDVWSIL
. ..|.||.|    | . || .    |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_TYP DDB0214883.AA LRR_TYP 515-538 41 7e-06 26.73 SMART 1-24 (24) Show / Hide 
Range on Protein: 515-538
Range on HMM: 1-24/24
Sequence Identity: 41% (10 aa)

MTNLVELRLRYNQLSSLPQNMLES
..|| ||.| .|||..||......
LPNLRELDLSNNQLTHLPPGAFQG
LRR_1 DDB0214883.AA LRR_1 517-539 25 0.004434 15.09 Pfam 1-26 (26) Show / Hide 
Range on Protein: 517-539
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

NLVELRLRY-N--QLS-SLPQNMLESN
|| .| |.. |  .|. ..| . . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 DDB0214883.AA LRR_1 540-551 46 3.515046 4.81 Pfam 1-15 (26) Show / Hide 
Range on Protein: 540-551
Range on HMM: 1-15/26
Sequence Identity: 46% (7 aa)

HLQVLWLEG-N--RL
.||.| | | |  .|
NLQHLDLSGCNCCNL
Kinase DDB0214883.AA DRK 851-1102 63 5.4e-216 723.85 In-house 1-258 (258) Show / Hide 
Range on Protein: 851-1102
Range on HMM: 1-258/258
Sequence Identity: 63% (164 aa)

IAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVN-LKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRGSLANILLDESIEMDWGLR
|.||.|||||.||.||||.||||.||||||||.|.| .........|..|.|.||||||..|||.|..|...||..||..||||.|||.||||||||.|.
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLAT----VKSHTFAKTMCGTTGWVAPEVLAEEGYTEKADVYSYAIVLWELLTRLI
.|..||||.||.|||..||||||||||..|||||..||||||||||.|    .|.|.||.|||||..|.|||||....|||||||||.||||||..||..
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQD

PYAGKNTMQVVRSIDR-GERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIMEG
||.|..|.|||.|..| |.|.|||.||||||..|||.||..||.||||..|.|...| 
PYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase DDB0214883.AA Dicty4 851-1102 49 3.5e-179 601.57 In-house 1-277 (277) Show / Hide 
Range on Protein: 851-1102
Range on HMM: 1-277/277
Sequence Identity: 49% (137 aa)

IAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVN--LKLISDLRKEVDLLCKLRHPNIVLFMGACT----EPSSPCIVTEYLSRGSLANILLD-----
|.|..|||.|..|.|..|.|||.|||||.|.|.|.|  .......||||...||.|||||.|||||||    .|...||||||...|.|...|.|     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-ESIEMDWGLRLQ---LGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLAT----VKSHTF-AKTMCGTTGWVAPEVLAEEGYTEKADV
 .||..||.|...   ..||.||||..||..||.|||||||..|||||..|.|||.||||..    ...|.. ..|.|||..|.||||.....|.|||||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSYAIVLWELLTRLIPYA--GKNTMQVVRSIDR-GERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPI--MEG
||..|||||.||| .||.  ....||.||.... ..|.|.|.||||....|...||..||.|||||.||...  .| 
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase DDB0214883.AA TKL 857-1100 30 6.6e-110 371.44 In-house 1-364 (364) Show / Hide 
Range on Protein: 857-1100
Range on HMM: 1-364/364
Sequence Identity: 30% (114 aa)

IGRGGYGQVFRGSWRG----------TEVAVKMLFNDNVNLKLISD-----------------------LRKEVDLLCKLR--HPNIVLFMGACTEPSS-
||.||.|.|..| |||          ..||||..  .|.... ...                        ..|. .....|  |||||.|||.|..|.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------PCIVTEYLSRGSLANILLDESIEMDWGLRLQLGFDCARGMTYLHSRN------PIIIHRDLKTDNLLVDDSWQ--------------V
            .|||.|| ..||| ..|.       | .|...  |.|||| ||||.|      | |||||||..|.|||. |.              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVADFGLATVKSHTFAKTM---------------------CGTTGWVAPEVLAEE----------------GYTEKADVYSYAIVLWELLTRLIPYA-GK
|..||||....|... ...                     |||..| ||||| ..                 |.||.||||..|||||.||| .||.  .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

NTMQV---------VRSIDRGERLPMP------------AWCPPKYAALMNRCWETDPTHRPSFPEILPIM
. ...         .  .|.|.|.|.|              ||| .. || .||..||. |||| ||| ..
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0214883.AA TKL-Unique 853-1100 37 1.9e-100 339.99 In-house 1-290 (290) Show / Hide 
Range on Protein: 853-1100
Range on HMM: 1-290/290
Sequence Identity: 37% (110 aa)

IGARIGRGGYGQVFRGSWRGTEVAVKMLF-NDNVNLKLISDLRKEVDLLCKLR-HPNIVLFMGACT----EPSSPCIVTEYLSRGSLANILL--------
... ||.||||||..| |||..||.| .. |  ...... ....|| .. ||. |||||..||.|.     |.  |||.||...||| . |         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-DESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDS-----WQVKVADFGLATVKSHT---FAK--------TMCGTTGWVAPEVLAE
  ....... .|...  |.|.|| |||...| |||||||. |.|||       |..|..||||....|     ...        | ||.. |.|||||  
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EGYTEKADVYSYAIVLWELLTRLI------PYAGKNTMQVVRSIDR---GERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIM
  . |.||.||||..|||||..|| |      || | .  |.   ..    . |.| |  ||. |  |...||  ||. |||| ||.   
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase DDB0214883.AA MLK 851-1100 34 7.3e-88 298.2 In-house 1-291 (291) Show / Hide 
Range on Protein: 851-1100
Range on HMM: 1-291/291
Sequence Identity: 34% (102 aa)

IAIGARIGRGGYGQVFRGSWRGTE-----VAVKMLFNDNVNLKLIS-----DLRKEVDLLCKLRHPN----IVLFMGACTEPSS-PCIVTEYLSRGSLAN
| .   || |..|.|..| ||...     ||||. . .    | ..     |...|. .| .|.|||    |. |.|.|..| .  |||.||.. |||.|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ILLDES-------------IEMDWGLRLQLGFDCARGMTYLHSRNP-IIIHRDLKTDNLLVDD------SWQVKVADFGLATVKSHTFA-KTM-CGTTGW
.| ...             . .| .. ..  ..||||| ||||  |  |||||||  |.|.|.        ..|..|||... .... . ..  .||  |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

VAPEVL---AEEGYTEKADVYSYAIVLWELLTRLIPYA-GKNTMQV-VRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIM
 ||||.    .| |.||.||.|...||||.||| .||. . . |..    .  |.|.|.|  ||.  . ||..||..||  |||| .|... 
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DDB0214883.AA LRRK 851-1102 29 2.5e-84 286.47 In-house 1-351 (351) Show / Hide 
Range on Protein: 851-1102
Range on HMM: 1-351/351
Sequence Identity: 29% (105 aa)

IAIGARIGRGGYG-QVFRGSWRG----------------------------TEVAVKMLFND----------NVN----------------------LKL
. |.  |||||.|  |.|. |||                            ..||.| .  |          . |                      .. 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRGSLANILLDES--------IEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLL
 . .|.|| ....|.|||||  .| | .|  .|.|.||.. |.|   | ...        ....|.|.|..  . |.|| ||||.|| |||||||..| |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

V---D---------DSWQVKVADFGLAT---VKSHTFAKTMCGTTGWVAPEVLA---EEGYTEKADVYSYAIVLWELLTRL-IPYAGKN-------TMQV
.   .         .   .|.||||. .   .  ...||.. |. ||.|||..    || ||||.|.||....|||||||. .|. . .       . |.
LWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

VRSIDRGERLPMPAW-CPP-----KYAALMNRCWETDPTHRPSFPEILPIMEG
   | .| | . |   |||      | .|.. ||..||. ||.| .|. ... 
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase DDB0214883.AA LISK 856-1100 34 4.9e-76 246.51 In-house 1-296 (296) Show / Hide 
Range on Protein: 856-1100
Range on HMM: 1-296/296
Sequence Identity: 34% (102 aa)

RIGRGGYGQVFRGSWR--GTEVAVKMLFN--DNVNLK-LISDLRKEVDLLCKLRHPNIVLFMGACTE-PSSPCIVTEYLSRGSLANILLD---ESIEMDW
 ||.|..|.|..|..|  |...|.||. .  . .|.. ..  . .|| .. .||||||| |||.| .  ..  ||||| . | | ..| |    .|   |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

GLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDS----WQVKVADFGLA---------------------------------TVKSHTFAK---T
 .|. .  | |.||.||||.|  |||||||  |.||...    |..||.|||.|                                  .|.   .|   |
PQRVKIALDIACGMSYLHSMN--IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMT

MCGTTGWVAPEVLAEEGYTEKADVYSYAIVLWELLTRLIPYA--GKNTMQVVRSIDRGERL-PMPAW-CPPKYAALMNRCWETDPTHRPSFPEILPIM
.|||. |.|||.|  . |.|..||.|. ||| |. ||  .     . |.|    .|  |..  ..   ||| .  |. .| . ||. |||| ||. . 
ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase DDB0214883.AA Dicty4-Unclassified 851-1100 36 2e-74 253.55 In-house 1-263 (263) Show / Hide 
Range on Protein: 851-1100
Range on HMM: 1-263/263
Sequence Identity: 36% (96 aa)

IAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVNLK--LISDLRKEVDLLCKLRHPNIVLFMGACTEP----SSPCIVTEYLSRGSLANILL------
| |   ||.|   .| .| |.| .|||| .          .| | .|||..|  . ||| |   |.|  |    |  |||.| . .| |  .        
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

DESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLATVKSHTFAKTMCG-TTGWVAPEVLAEEGYTEKADVYSYAIVL
. .| .|  | .   || |.|| .||.||  .||||.|  |.|.|    .|.||||.. | . .|  |  . |  | .||.|  | |. |.||||||..|
QQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMML

WELLTRLIPYAGKN-TMQVVRSI-DRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIM
.||.|   || .    | . ||. |.. |  .|  |.. .  |   ||  ||  ||.. .|   .
YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase DDB0214883.AA TKL-ciliate2 851-1101 40 5.6e-73 242.87 In-house 1-273 (273) Show / Hide 
Range on Protein: 851-1101
Range on HMM: 1-273/273
Sequence Identity: 40% (111 aa)

IAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRGSLANILLDESIEMDWGLRL
. |  .|  |||| ...  || . ||||    |  | . | |   | . .  |||||||.|.||||.    ||. ||  ||||  .| .... . |  | 
LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRR

QLGFDCARGMTYLHSRNPIIIHRDLK--------------------TDNLLVDDSWQVKVADFGLATVK-SHTFAKTMCGTTGWVAPEVLAEEGYTEKAD
..  | |||. |||| || |||||||                      |.||||    |..|||   ||    .     ||  |.||||.    ||||||
RIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKAD

VYSYAIVLWELLTRLIPYAGKNTMQV-VRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIME
|.||.|.|||.  |  || .|    | .. .    |  .|  |||..| || |||. .   |||| ||.  .|
VFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase DDB0214883.AA Shk 851-1105 40 7.7e-72 244.98 In-house 1-269 (269) Show / Hide 
Range on Protein: 851-1105
Range on HMM: 1-269/269
Sequence Identity: 40% (110 aa)

IAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACT-EPSSPCIVTEYLSRGSLANILLDESIEMD--WG
|   . .| | .| |  |  || ||||| .   |. ..  .. |||| .  |..||||.|||||||  |    ||||   .|.|   |.|  .. .    
INREDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILY

LR-LQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLAT-VKSHT----FAKTMCGTTGWVAPEVLAEEGYTEKADVYSYAIVLWELL
.| ...  | | ||. ||. |. |||||||| |||||  | |||.|||.    | |.      |   ||  | ||||.    | |||||||  |.|||.|
KRAMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPYNEKADVYSFGIILWEIL

TRLIPYA--GKNTMQVVRSI-DRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPI--MEGMIS
|.  ||    ..  . .  |    || | |. ||.    |  .||  .|  |||| ||.    ..  . 
TCQEPYPKHHSEYDKFYEAICNKKERPPIPDDCPKSLKHLIQKCWDHNPQRRPSFNEIIQRRILNHILI
Kinase DDB0214883.AA Pkinase 851-1097 26 1.1e-65 229.37 Pfam 1-288 (293) Show / Hide 
Range on Protein: 851-1097
Range on HMM: 1-288/293
Sequence Identity: 26% (77 aa)

IAIGARIGRGGYGQVFRGSWRGTE--VAVKMLFNDNVNLKLISDLRK--EVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRG----SLANILL-DES
. || .||.|..|.|... ..||.  |||| .  .. . .    .|.  |. .. .|.||||| . ...........|.||.  |    .|. ..  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IEM--DWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQV----KVADFGLAT---VKSHTFAKTMCGTTGWVAPEVLA-EEGYTEKADVY
  .  ..          .||. |.||.   ||||||| .|.|.|.  ..    |..|||||      . . ..| ||| ...||||.   ..|. |.|..
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYAIVLWELLTRLIPYAGK------NTMQVVRSIDRGERLPM-PAWCP-------------------PKYAALMNRCWETDPTHRPSFPEIL
|. ..|.|.|..  |. |.      . ||... | ...     | ||.                   .    ....|.. ||. ||....||
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL
Kinase DDB0214883.AA TyrKc 851-1100 31 1.7e-64 221.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 851-1100
Range on HMM: 1-280/280
Sequence Identity: 31% (92 aa)

IAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKL--RHPNIVLFMGACTEP-------SSPCIVTEYLSRGSLANILLDES
|  |  .|.| .|.|..| |. ..|||||| .|      . |...|  ..|||  .||||| . |.||..         ..||.|| . |.| . | .  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

IEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLATVKSHT-------FAKTM----CGTT----GWVAPEVLAEEGYTE
 .  .   |.  .. |.|| ||||.|  .||||| . | ||..  .||..||||.    .          ...    .| |     | |||.. .  .|.
PKLCMKDLLSFCWQIACGMEYLHSKN--CIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADVYSYAIVLWELLTR-LIPYAG-----KNTMQVVRSIDRGERLPMPAW--------CPPKYAALMNRCWETDPTHRPSFPEILPIM
| ||.|. ...||..|.   || |     ..  .|.. ...|.|.| |.         ||..   .| .||. ||  ||.| ||  ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0214883.AA S_TKc 851-1100 26 5.6e-58 199.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 851-1100
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

IAIGARIGRGGYGQVFRGSWRG--TEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSR--GSLANILLDESIE---
  |.  ||.|..|.|... ...   .||.|..           ..|.|...| | .||||| . ... . .. ..|.||..   |.|  .. .   .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--MDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLATVKSHTFAKTMCGTTGWVAPEVLAEEGYTE-KADVYSYAIVLWEL
  ..      .    .... |.||..  ||||||| .|.|.|.  ..|..|||||..      .|.|||  ..|||||   ||.  |.|..|  ..|.|.
FPFPE-HARFYMYQICCALEYCHSHG--IIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTRLIPYAGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEIL---------PIM
|..  |.   . ... . |            .|    ....|.. ||..||.  |.|         | .
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0214883.AA Pkinase_Tyr 851-996 35 6.6e-45 152.71 Pfam 1-158 (270) Show / Hide 
Range on Protein: 851-996
Range on HMM: 1-158/270
Sequence Identity: 35% (57 aa)

IAIGARIGRGGYGQVFRGSWR------GTEVAVKMLFNDNVNLKL--ISDLRKEVDLLCKL-RHPNIVLFMGACTEPSSP---CIVTEYLSRGSLANILL
| .|  .|.| .|.|..| |.      ...|||||| ...   .   . |. .|. ....| .||||| ..|.||. . |   .||.||   |.| . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DE---SIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLA
.        .    ||  .. |.|| ||.|.|  .||||| . | ||... .||..|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLA
Kinase DDB0214883.AA Pkinase_Tyr 1013-1100 37 2.2e-31 106.89 Pfam 180-270 (270) Show / Hide 
Range on Protein: 1013-1100
Range on HMM: 180-270/270
Sequence Identity: 37% (34 aa)

WVAPEVLAEEGYTEKADVYSYAIVLWELLTRL-IP-YAGKNTMQVVRSI-DRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIM
| |||....  .|.| ||.|. ...||..|.  .| |.|    .|.. | ..|.|.|.|  ||..   || .||. || .||.| ||. ..
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL