Gene DDB0220436 (Slime mold)

DDB0220436

Species: Slime mold
Alias: DdisK240, DDB0220436
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
DDB0220436.AA Protein None 967 None Fasta, JSON
DDB0220436.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of DDB0220436.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0220436.AA TKL-Unique 347-606 34 2.2e-119 402.93 In-house 1-290 (290) Show / Hide 
Range on Protein: 347-606
Range on HMM: 1-290/290
Sequence Identity: 34% (102 aa)

DSNKIGEGGQCSIYKYMG----TAMKRFKP-SLSSSLISKEFENEVLILERLN-HPNIVKIITYST------IERIILLEFIDGNSLDKYPSQSLPLS--
..|||||||....||...    .|.|.|.| ..||. ...|||||| ....|. |||||....|..      ....| .|...|.||.....|.....  
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-PSSSLPNPLKVIQDFQQIVDAMIYLHNEIG-IIHFDLKPSNILKNSKN----NKLKLIDFGISKFLNNNNQNNNNNS------LNMGSYRYSPPELLCN
 .... .|..........|...|.|||.... |||.|||.||.|.....    .. |..|||.|||....|...||..       ..||.|...||.|..
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

NNQNNNLINKSVDVFSFGIMLWECLNWTL------PYESLSREQVKQIKTDMERESHLPL-DHLPKGIQDLIRLCWKHDPSIRPSFIEIRSRL
|.   .......||.||||.|||......      ||.....||.......||.....|. .|.|| ..|||. ||.||||.||||.||..||
NF---CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase DDB0220436.AA TKL 351-606 21 1.8e-65 223.82 In-house 1-364 (364) Show / Hide 
Range on Protein: 351-606
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

IGEGGQCSIYKY--MG------------TAMKRFKP--SLSSSLIS-----------------------KEFENEVLILERLNHPNIVKIITYSTIER--
||.|| . .||   .|             |.|.||   . .....|                       ...|.|.... ||.|||||... |.. ..  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------IILLEFIDGNS-LDKYPSQSLPLSPSSSLPNPLKVIQDFQQIVDAMIYLHNEI-------GIIHFDLKPSNILKNSKNN--------
              |  |...| | |. .               . . ..  ..|  .| |||...       .||| |||..||| .....        
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYN

-----KLKLIDFGISKFLNNNN----------------QNNNNNSLNMGSYRYSPPELLCNNNQNNN-----------LINKSVDVFSFGIMLWECLNWT
     ..|. |||.|.|.....                .|.....   |..|. .||.| .......             ....||.||||.|||.|   
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

LPYESLSREQVK---------QIKTDMERESHLP-----------LDHLPKGIQDLIRLCWKHDPSIRPSFIEIRSRL
.||. .  ....          .  |  .   .|            .. |... .|.  ||.|||. |||| || .||
RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DDB0220436.AA Ciliate-E2-Unclassified 345-602 19 6.9e-34 114.94 In-house 1-346 (352) Show / Hide 
Range on Protein: 345-602
Range on HMM: 1-346/352
Sequence Identity: 19% (70 aa)

FNDSNKIGEGGQCSIYKY----------MGTAMKRFKPSLSSSLISKEFENEVLILERLN-------------------HPNIVKIITY--STIERIILL
..   .||.||....||           | ...|  . .  . . ..|. || .......                   ||.||| . .  ..   .| .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFIDGNSLDKYPS-------------------QSLPLSPSSSLPNPLKVI---QDFQQIVDAMIYLHNEIGIIHFDLKPSNILKNSKNN--KLKLIDFGI
|...|..| .| .                   . ..   ...       .   . | ||...  ||| . .||| |.||.||| .....  ..|.|||||
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKY-------KKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI

SKFLNNNNQN------------NNNNSLNMGSYRYS----PPELLCNNNQNNNLINKSVDVFSFGIMLWECLNWTLPYESLSREQ--------------V
||....||..            ... . ..|...|     .||.|...|...    ...|..|.|. | |.|  ..|... ..||               
SKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

KQIKTDMERESHLPL-------DHLPKGIQDLIR----LCWKHDPSIRPSFIEI
 ...  ....   |        .|...  .|.|.     . | .|. |..| .|
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase DDB0220436.AA S_TKc 345-610 23 1.2e-31 112.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 345-610
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

FNDSNKIGEGGQCSIYKYMGTA------MKRFKPSLSSSLISKEFENEVLILERLNHPNIVKIITYST-IERIILLEFIDG--NSLDKYPSQSLP-----
.   .|||.|.  . ||   .       .|. |         . ...|. ||.. .||||||.. .    .  . .|..||   .| .|  .  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSPSSSLPNPLKVIQDFQQIVDAMIYLHNEIGIIHFDLKPSNILKNSKNNKLKLIDFGISKFLNNNNQNNNNNSLNMGSYRYSPPELLCNNNQNNNLIN
 ..       .  .   ..||..|. |.|.  |||| ||||.||| ..    .|..|||....|          .   |.  | .||.|          .
PFP-------E-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKICDFGLARQL----------TTFCGTPWYMAPEVL--------GYG

K-SVDVFSFGIMLWECLNWTLPYESLSREQVKQIKTDMERESHLPLDHLPKGIQDLIRLCWKHDPSIRPSFIEIRS-----RLSEII
| ..|. |.|..|.|.|    |..    .  |.|.              ..   |.|| |.. ||. ||.  |.       .. . .
KCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0220436.AA MLK 345-606 23 6.1e-31 104.63 In-house 1-291 (291) Show / Hide 
Range on Protein: 345-606
Range on HMM: 1-291/291
Sequence Identity: 23% (71 aa)

FNDSNKIGEGGQCSIYK--YMGTA-------MKRFKPSL----SSSLISKEFENEVLILERLNHPN----IVKIITYSTIE---RIILLEFIDGNSLDKY
.. . .||.|.... .|  . ..         ||.. .     ... ....|| |. .| .|.|||    |...   .. .     |..|...| ||  .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

P--SQSLPL-----SPSSSLPNPLKVIQDF-QQIVDAMIYLHNEIG--IIHFDLKPSNILKNS-----KNNKLKLIDFGISKFLNNNNQNNNNNSLNMGS
    .| .       . ..   .. .. ..  |.  .| |||..    |||.|||..|||        .. .||  |||.|......     |   |.|.
LHGARSKWMDANHNQK-NDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC---TNMMSNAGT

YRYSPPELLCNNNQ-NNNLINKSVDVFSFGIMLWECLNWTLPYE-SLSREQVKQIKTDMERESHLPLDHLPKGIQDLIRLCWKHDPSIRPSFIEIRSRL
|..  || .    |  ..  ....||.|.|..||| |   .||.  ..  ..    .  .   ..| .  |...  |.  ||. ||. |||| .| . |
YAWMAPEVI---QQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST-CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DDB0220436.AA Pkinase 366-606 21 9.7e-31 109.77 Pfam 28-293 (293) Show / Hide 
Range on Protein: 366-606
Range on HMM: 28-293/293
Sequence Identity: 21% (61 aa)

AMKRFKPSLSSSLISKEFEN--EVLILERLNHPNIVKIITYST--IERIILLEFIDGN----SLD----KYPSQSLPLSPSSSLPN--PLKVIQD-FQQI
|.|..| .  .|   ..  .  |. |. ||||||||... . .   .  . .|. .|     .|                ... .   . ..... . ||
AVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST----------WRHGCFYFSEWECKFYMYQI

VDAMIYLHNEIGIIHFDLKPSNILKNSKNNK---LKLIDFGISKFLNNNNQNNNNNSLNMGSYRYSPPELLCNNNQNNNLINKSVDVFSFGIMLWECLNW
. .. |.|.  |||| ||||.||| .....    .|..|||..|...  . ||  ..   |...| .||..      .. . ..||..|.|..|.| |. 
LRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKVDMWSCGCILYEMLCG

TLPYESL------SREQVKQIKTDMERESHLPLDHL------------------PKGIQDLIRLCWKHDPSIRPSFIEIRSR--L
 .|. .       .  |. . . . . ... | ..                   ..  .|.|. |.. ||. ||.. .|     .
RPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0220436.AA Ciliate-E2 345-602 18 1e-29 99.21 In-house 1-359 (365) Show / Hide 
Range on Protein: 345-602
Range on HMM: 1-359/365
Sequence Identity: 18% (70 aa)

FNDSNKIGEGGQCSIYKY-----------------------------MGTAMKRFKPSLSSSLISKEFEN----------EVL-ILERLNHPNIVKII-T
..  .|||.|.. |.||                              .  |||..|..   .. ... ..          . . |||.||||||.|.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YSTIER---IILLEFIDGNSLDKYPSQSLPLSPSSSLP-----NPLKVIQDFQQIVD---------------AMIYLHNEIGIIHFDLKPSNILKNSKNN
. .. .    . .|...|..| .|  .. ...  . ..     .  .... ..||..               |. |||..  ||| |.||.|||      
FQEKDDNNIYLVMEYCQGGDLFDY-IKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

KLKLIDFGISKFLNNNNQNNN-----NNSLNMG------------------------SYRYSPPELLCNNN----QNNNLINKSVDVFSFGIMLWECLNW
 .|.||||.||.....|||.      .. .. .                        .. | .|| | . .    |. .  ....|..|.|..| |.|  
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

TLPYESLSREQVKQIKTDMERESHLP-----------------LDHLPKGIQDLIRL----CWKHDPSIRPS-FIEI
 .|.          ..  .. .  .|                  .....  .|||.     . . ||. |.. . .|
KPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase DDB0220436.AA RIPK 448-606 28 1.1e-23 77.57 In-house 114-290 (290) Show / Hide 
Range on Protein: 448-606
Range on HMM: 114-290/290
Sequence Identity: 28% (50 aa)

QQIVDAMIYLHNEI-GIIHFDLKPSNILKNSKNNKLKLIDFGISKFLNNNNQNNNNN---------SLNM-GSYRYSPPELLCNNNQNN-NLINKSVDVF
..|. .| |||.    ||| ||||.|||  . |   |. ||| ....    ...            |.|  |   | |||.. ..| .    ...  || 
HEISCGMCYLHSMNPPIIHRDLKPENILVDN-NFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVY

SFGIMLWECLNWTLPYESLSREQVKQIKTDMERESHLP--LDHLPKG-----IQDLIRLCWKHDPSIRPSFIEIRSRL
||.| .|| |    |||    .... .. .      |.   .  |.      . .|...||. ||  ||.|.|.... 
SFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase DDB0220436.AA ULK 447-565 26 2.4e-21 71.31 In-house 136-270 (329) Show / Hide 
Range on Protein: 447-565
Range on HMM: 136-270/329
Sequence Identity: 26% (37 aa)

FQQIVDAMIYLHNEIGIIHFDLKPSNILKNSKNNK-----------LKLIDFGISKFLNNNNQNNNNNSLNM------GSYRYSPPELLCNN--NQNNNL
|.||. .. .|| . .||| |.||.||| . .. |           ||. ||| .|...|.|.... .          |.  |  |..| ..  ... . 
FKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYY-

INKSVDVFSFGIMLWECLNWTLP-YESLSREQVKQIKTD
 .. .|..|.|... |.|    | |..  ..|..||...
-DYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQK
Kinase DDB0220436.AA STE 448-601 21 1.1e-20 69.91 In-house 158-350 (359) Show / Hide 
Range on Protein: 448-601
Range on HMM: 158-350/359
Sequence Identity: 21% (44 aa)

QQIVDAMIYLHNEIGIIHFDLKPSNILKNSKNNKLKLIDFGISKFLNN-------NNQNNNNNSLNMGSYR-------YSPPELLCNNNQN-NNLINKSV
.||. .. |.. . .||| |.||.|||        ||.|||... |..       || . ......|.. |       .  || . .|.|. ..  . ..
RQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVCGQLTDSMANIQSNN-I-IDCIETMQQKRNTFVGTPWMAPEVIQQNGQGRDKGYDTKC

DVFSFGIMLWECLNWTLPY---ESLSREQVKQIKTDMER---------ESHLPL-DHLP-------------------KGIQDLIRLCWKHDPSIRPSFI
|. |.|....| ..   |.     ..    ..... |..         . . || |||                    .  .| |..| . ||. ||.  
DIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS

E
.
Q
Kinase DDB0220436.AA ULK 447-553 27 1.6e-20 69.57 In-house 132-254 (324) Show / Hide 
Range on Protein: 447-553
Range on HMM: 132-254/324
Sequence Identity: 27% (35 aa)

FQQIVDAMIYLHNEIGIIHFDLKPSNILKNSKNNK-----------LKLIDFGISKFLNNNNQNNNNNSLNM------GSYRYSPPELLCNN--NQNNNL
|.||. .. .||.. .||| |.||.||| . .. |           ||. ||| .|...|||.. . .          |.  |  |..| ..  ... . 
FKQICNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYY-

INKSVDVFSFGIMLWECLNWTLPYES
 .. .|..|.|... |.|    |..|
-DYKCDIWSLGCIFYEMLYGKYPFFS
Kinase DDB0220436.AA LRRK 532-608 34 1.5e-17 58.65 In-house 263-351 (351) Show / Hide 
Range on Protein: 532-608
Range on HMM: 263-351/351
Sequence Identity: 34% (31 aa)

VDVFSFGIMLWECLNWT-LPYESLS-------REQVKQIKTDMERESHLPLD-HLPK----GIQDLIRLCWKHDPSIRPSFIEIRSRLSE
||..|||. |||.|  . .|.. ..       .||.... ..  | . .| .  .|.      |||| .||.|||  ||.|..| .|||.
VDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPT-IPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase DDB0220436.AA TyrKc 345-606 23 4.4e-16 37.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 345-606
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

FNDSNKIGEGGQCSIYKYMGT---AMKRFKPSLSSSLISKEFENEVLILERL--NHPNIVKIITYSTIE---------RIILLEFIDGNSLDKYPSQSLP
     |.|||  . .|| . .   | |  |..       ..| .|  |. .|  .|||||... . | .           |..|. .. .|..|   . |
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

LSPSSSLPNPLKVIQDFQQIVDAMIYLHNEIGIIHFDLKPSNILKNSKNNKLKLIDFGISKFLNNN-----NQNNNNN----SLNM-GSYRYSPPELLCN
        .. . ..   || . | |||   ..|| ||   |.| ....   |  ||| |... .      ..         . ..   .|  .|| .  
K------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

NNQNNNLINKSVDVFSFGIMLWECLNW-TLPYES-----LSREQVKQIKTDMERESHLPLD------HLPKGIQDLIRLCWKHDPSIRPSFIEIRSRL
   | .  .   ||.|||...|| .     ||.      .| ..| .   . .|    | |      . |. . .... ||..||. ||.| ||....
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DDB0220436.AA Pkinase_Tyr 578-606 48 7.4e-08 27.24 Pfam 242-270 (270) Show / Hide 
Range on Protein: 578-606
Range on HMM: 242-270/270
Sequence Identity: 48% (14 aa)

PKGIQDLIRLCWKHDPSIRPSFIEIRSRL
|. | ||...||..||. ||.| ||...|
PDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase DDB0220436.AA STE 345-423 20 8e-07 20.25 In-house 1-126 (359) Show / Hide 
Range on Protein: 345-423
Range on HMM: 1-126/359
Sequence Identity: 20% (26 aa)

FNDSNKIGEGGQCSIYKYMGT---------------------AMKRFK---------------PSLSSSLISKEFENEVLILERLN--HPNIVKIITYST
. .  |||.|.  . || |                       |.|. .               .. . . . .....|. |. ..|  |||||| . .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---------IERIILLEFIDGNSLDK
          |  | .|..|| |||.
KEGHNHKNDDELWICMEYMDGGSLDD
Kinase DDB0220436.AA LRRK 449-490 42 1e-05 16.24 In-house 172-225 (351) Show / Hide 
Range on Protein: 449-490
Range on HMM: 172-225/351
Sequence Identity: 42% (23 aa)

QIVDAMIYLHNEI-GIIHFDLKPSNILK-NSKNN----------KLKLIDFGIS
|| ..| |||.    ||| |||. |||   |..|          . |..|||||
QIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGIS
Kinase DDB0220436.AA Pkinase_Tyr 366-424 25 4.4e-05 17.83 Pfam 32-97 (270) Show / Hide 
Range on Protein: 366-424
Range on HMM: 32-97/270
Sequence Identity: 25% (17 aa)

AMKRFKPSLSSSL-ISKEFENEVLILERL-NHPNIVKIITYST-----IERIILLEFIDGNSLDKY
| |  |.. ...  ....| .|. |.  | .|||||. .   |     .. .| .|.  . .|..|
AVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY
Kinase DDB0220436.AA LRRK 218-424 9 0.000103 12.59 In-house 72-145 (351) Show / Hide 
Range on Protein: 218-424
Range on HMM: 72-145/351
Sequence Identity: 9% (20 aa)

SSSINNSSNNNSNISSSPLSSSPLTLSSSSSSSSPLQRIQSIQNLIRSNSLRTSLSSSSSLLPNLIQLQQQQLPPPPPSQQQQQQQQQQQQQNNSMLQQS
.|. || .|||                                                                                         
NSNNNNNLNNNN----------------------------------------------------------------------------------------

NNNNISPRTQLLNNTTTLLPNNGLEEIFNDSNKIGEGGQCSIYKYMGTAMKRFKPSLSSSLISK---EFENEVLILERLNHPNIVKIITYSTIERIILLE
                                                 .  . ... ..  ..   || .|| |. .|||||||... ..   ... .|
-----------------------------------------------SEQVED-MDQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVME

FIDGNSLDKY
...  .|...
YAPHGDLYHF
Kinase DDB0220436.AA ULK 345-402 20 0.000246 11.14 In-house 1-84 (329) Show / Hide 
Range on Protein: 345-402
Range on HMM: 1-84/329
Sequence Identity: 20% (17 aa)

FNDSNKIGEGGQCSIYKY--MGT-----AMKRFKPSLSSSLISKE-----------FENEVLILERLN--------HPNIVKII
.. ....|.|     ||   . |      .   |  ...... |.           ..||. |. .|.        |||||| .
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLY
Kinase DDB0220436.AA ULK 379-402 34 0.099833 1.98 In-house 53-81 (324) Show / Hide 
Range on Protein: 379-402
Range on HMM: 53-81/324
Sequence Identity: 34% (10 aa)

ISKEFENEVLILERLN---HPN--IVKII
. . ..||. |.  |.   |||  ||| .
MWQLLKNEIQIMKKLKELKHPNHHIVKLY
Kinase DDB0220436.AA Pkinase_Tyr 533-543 63 0.381808 4.5 Pfam 196-206 (270) Show / Hide 
Range on Protein: 533-543
Range on HMM: 196-206/270
Sequence Identity: 63% (7 aa)

DVFSFGIMLWE
|| |||. .||
DVWSFGVLMWE