Gene DPYK2 (Slime mold)

DPYK2

Species: Slime mold
Alias: DdisK211, DPYK2, DDB0191483, splB, KYK2
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: DPYK

Sequence

Name Sequence Type Origin Length Description Download
DPYK2.AA Protein None 1155 None Fasta, JSON
DPYK2.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of DPYK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DPYK2.AA TKL 859-1109 28 1.5e-107 363.6 In-house 1-364 (364) Show / Hide 
Range on Protein: 859-1109
Range on HMM: 1-364/364
Sequence Identity: 28% (106 aa)

VGEGAFSEVWEGWWKG----------IHVAIKKLKIIG-------------------------DEEQFKERFIREVQNLKKGNHQNIVMFIG--------
.|.|.|.||. | |.|            ||.||.|.                           . ..|......|.  ... .|.||| |.|        
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-ACYKP------ACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLHLHSIT--------IVHRDLTSQNILLDELGN----------
 .|..|       ||..||. ||||...||            ... ...| |.|.|. .||| .        |.||||.|.|||.|| ..          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----IKISDFGLSREKSREGSMTMT----------------NGGIC-NPRWRPPELTKNL---------------GHYSEKVDVYCFSLVVWEILTGEIP
    .||.||||||..|..|.|..|                .. .| .||| .||. ..                . ||||.||| | .| |||||...|
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

FSDLDGSQAS---------AQVAYAGLRPPIP------------EYCDPELKLLLTQCWEADPNDRPPFTYIVNKL
..|.. ..           ..|.. |||||||            ..|.|..| |...||..||..|| |. |. .|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase DPYK2.AA TKL-Unique 855-1109 37 3.5e-98 332.49 In-house 1-290 (290) Show / Hide 
Range on Protein: 855-1109
Range on HMM: 1-290/290
Sequence Identity: 37% (109 aa)

FIQKVGEGAFSEVWEGWWKGIHVAIKKLKI-IGDEEQFKERFIREVQNLKKGN-HQNIVMFIGACY----KPA--CIITEYMAGGSLYNILH--NPNS--
|. |.|||....|  | |.|. ||||....  . . .... |..||  .|| . | ||| ..|.|     .|.  ||..||. |||||. ||  |.|.  
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

STPKVKYSFPLVLKMATDMALGLLHLHSIT--IVHRDLTSQNILLDEL-----GNIKISDFGLSREKSREGSMTMTN-------GGICNPRWRPPELTKN
  .. | .. ...||| |.|.|. .||.    | ||||.|.|.|.|.       ||||.|||||. .|..  || ..       . . ..||..||....
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

L-GHYSEKVDVYCFSLVVWEILTGEI------PFSDLDGSQASAQVAY--AGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKL
.  .||||.||| |. |.|||.|..|      |....|  |  . |.|   ..|||||. | .|.. |..|||  || .|| |. |...|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Pkinase_Tyr DPYK2.AA Pkinase_Tyr 853-1109 35 1.5e-96 327.66 Pfam 1-270 (270) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-270/270
Sequence Identity: 35% (96 aa)

IQFIQKVGEGAFSEVWEGWWK------GIHVAIKKLKIIGDEEQ-FKERFIREVQNLKKG-NHQNIVMFIGACY---KP--ACIITEYMAGGSLYNILHN
|.|..| ||||| ||..| ||      .|.||.|.||   ..|| ..| |.||.. .|.  .|.||| ..|.|.   .|   .|..|||..|.|.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

PNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSM-TMTNGGICNPRWRPPELTKNLGHYSEKVDV
.   ..| . . .  |.|... | |. .|.|. ..||||   |.|..| . .||.||||.|    ..   ... || .  .| .||  ..   ...| ||
HR--EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDV

YCFSLVVWEILT-GEIP-FSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKL
. |  . |||.| ||.| . ... ..  ....  | | |.||.| .|.  |..|||..||.||| |..|...|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase DPYK2.AA MLK 853-1109 35 1.1e-88 300.97 In-house 1-291 (291) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-291/291
Sequence Identity: 35% (105 aa)

IQFIQKVGEGAFSEVWEGWWKGIH-----VAIKKLKI----IGDEEQFKERFIREVQNLKKGNHQN----IVMFIGACYKP---ACIITEYMAGGSLYNI
||| ...|.|.| .|| |.|..       ||.|. ..    ..|..  .. | .|.  |.. .|.|    |. | |.| .|    ||..||..||||||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHN-PNSSTPK-------VKYSFPLVLKMATDMALGLLHLHSIT---IVHRDLTSQNILLDE------LGNIKISDFGLSREKSREGSMTMTN-GGICNP
||. .. . .        . |.. .... |...| |.  |||     |.|||| |.|||.||       |. ||.|||.||.... .  .|..  |  ..
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAG--TY

RWRPPELT--KNLGHYSEKVDVYCFSLVVWEILTGEIPFS-DLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKL
.|. || .  .  . ||||.||. . .| ||.||.|.|.. ..|.... ..||| |||||||  |.. .| |..|||..||..|| | .|| .|
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase DPYK2.AA Dicty4 853-1111 37 1.2e-78 261.96 In-house 1-277 (277) Show / Hide 
Range on Protein: 853-1111
Range on HMM: 1-277/277
Sequence Identity: 37% (104 aa)

IQFIQKVGEGAFSEVWEGWWKGIHVAIKKL--KIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACY----KP--ACIITEYMAGGSLYNILHN-PNSS
|.. |. |.|.|.||  | |.|. ||.|||  . ....| . . | .||  ..|  | ||. | |||     .|   || ||||  |.||..||. |   
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

TPKVKYSFPLVLK---MATDMALGLLHLHS-I-TIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTM-TNGGICNPRWRPPELTKNLGHYSEKVD
 ...| ..||...   || | |.|. .||. .  |.|||| | |.| |.  ..|..|||||. . .. . .  . . .  | |  ||   . . | ||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEKAD

VYCFSLVVWEILTGEIPFS--DLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNK--LKE
|| |..| |||||...|..    .  |. . |.  .|||||| .|.| .| |.. ||. ||. || |  |...  | .
VYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase DPYK2.AA HH498 853-1109 32 3.7e-77 244.1 In-house 1-284 (284) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-284/284
Sequence Identity: 32% (92 aa)

IQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFK------ERFIREVQNLKKGNHQNIVMFIGACY---KPACIITEYMAGGSLYNIL------
| |  |.| |.| .|  | | .  ||.|  ..    .  .       .|.|||  . . || . | |..||    .   |.|.| ..|||. ||      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

---HNPNSSTPK---VKYSFPLVLKMATDMALGLLHLHS---ITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGICNPRWRPPELTKN
    | |    |      . .  . .. | | |   ||.     |.||||.|.|||..| |  .. ||| || .   .  .||   . |.||. || .. 
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQ-PGNLRWMAPEVFSQ

LGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQASAQVAYAGLRPPIPEY----CDPELKLLLTQCWEADPNDRPPFTYIVNKL
 . ||.||||. . ...||..|.|.||...    |.| .||.  |||||       .     |. .||.. |..|| |  || .|
CQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase DPYK2.AA DRK 853-1111 37 5.8e-67 225.83 In-house 1-258 (258) Show / Hide 
Range on Protein: 853-1111
Range on HMM: 1-258/258
Sequence Identity: 37% (99 aa)

IQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDE-EQFKERFIREVQNLKKGNHQNIVMFIGACYKPA--CIITEYMAGGSLYNILHNPNSSTPKVKY
|     .| | . ||. | | |. ||.|.|.    . | |   | ||.  ...  | ||. |.|.|  |   ||..|||  ||||||||.     .... 
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHD-----ESIEM

SFPLVLKMATDMALGLLHLHSIT--IVHRDLTSQNILLDELGNIKISDFGLSR--EKSREGSMTMTNGGICNPRWRPPELTKNLGHYSEKVDVYCFSLVV
. ||...|. | | |.  ||. .  |.|||| | | | ||   .|..|||||    | ..   .||  |   | |  ||   | . | || ||| |  | 
DWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGT--PCWTAPEVLRNQR-YTEKADVYSFAIVL

WEILTGEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKE
||..| ..|.      |    |   |.|||.|..| |    |.. ||. ||  || .  ..  |  
WECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase DPYK2.AA TyrKc 853-1109 32 7.9e-65 222.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-280/280
Sequence Identity: 32% (94 aa)

IQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKERFIREVQNLKKG--NHQNIVMFIGACY---------KPACIITEYMAGGSLYNILHNPN
|....| ||||| ||..| || | ||.|.||        .| |.|| . ..|   .|.||| ..|.|          .| .|..|||..|.| . |... 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

SSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSRE------GSMTMTN---GGI--CNPRWRPPELTKNLG
        . .  |..... | |  .|||  ..||||   |.|..| . .|||||||||.   .      ... ..    ||      || .||   | |
PK-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

HYSEKVDVYCFSLVVWEILT-GEIPFSD-----LDGSQASAQVAYAGLRPPIPEY--------CDPELKLLLTQCWEADPNDRPPFTYIVNKL
 ...| ||. |  . |||.| |. | ..     .. ... ..|  .| |.|.|..        | .|.  . .|||..||.||| |. |. ..
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK-QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase DPYK2.AA LRRK 853-1111 28 1.3e-64 221.01 In-house 1-351 (351) Show / Hide 
Range on Protein: 853-1111
Range on HMM: 1-351/351
Sequence Identity: 28% (102 aa)

IQFIQKVGEGAFS-EVWEGWWKG----------------------------IHVAIKKLKIIG----------DE-----------------------EQ
. . ...|.|.|  .|  . |.|                              |||||.....          .                        . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FKERFIREVQNLKKGNHQNIVMFIGACYKPACIITEYMAGGSLYNILHNPNSST----PKVKYSFPLVLKMATDMALGLLHLHSIT--IVHRDLTSQNIL
| | | .||  . . || |||  .| | .| |...||.  |.||  |||. ..     .  . |  |.|| |.. | |. .||| .  |.||||.| |||
FRE-FRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMK-AHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

L---D---------ELGNIKISDFGLSREKSREGSMTMTNGGICNPRWRPPELTKNL--GHYSEKVDVYCFSLVVWEILTGE-IPFSDLD---GSQASAQ
|   .         .  ..||.|||.||       |. ..|   ||.|. ||  ..     |.||||.| | .. ||.||.. .|| ..|    .|   |
LWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

VAY---AGLRPPIPEY-CDP-----ELKLLLTQCWEADPNDRPPFTYIVNKLKE
.      ||||.||.  | |     ... |...||..||..|| |..|| .|..
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase DPYK2.AA Dicty4-Unclassified 853-1109 37 5.7e-64 217.96 In-house 1-263 (263) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-263/263
Sequence Identity: 37% (103 aa)

IQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKER------FIREVQNLKKGNHQNIVMFIGACYKP------ACIITEYMAGGSLYNILH-N
||  | .|.|.||.|  | |||  ||.||.     | .|| |      | .||  |    | | |   |.|  |       ||..| |  | |  . |  
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKF----NENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSK

PNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGIC-NPRWRPPELTKNLGH--YSEKV
|      .|    |..|.| | | |. |||.  ..|||. | |||.|   |||| |||.||. .    ||     |   |.|  ||    | |  |  | 
PSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTT----IAGTPKWESPEC---LMHESYNQKS

DVYCFSLVVWEILTGEIPFSDLD-GSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKL
||| . .. .| .||. |. .      |   |.  .||| ||. ||. .| |   ||  ||| || .  |...|
DVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase DPYK2.AA TK 853-1109 18 3.5e-59 196.7 In-house 1-486 (486) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-486/486
Sequence Identity: 18% (88 aa)

IQFIQKVGEGAFS---EVWEGWWKG---------------------------IHVAIKKLK--IIGDEEQFKE-------------RFIREVQNLK--KG
|....| |||.|    ||..|.|.|                           . ||.| ||     ..|.|..             .. .| . ..  .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHQNIVMFIGACYKP--------------ACIITEYMAGGS----LYNILHNPNSSTPKVKYSFP-----------------------------------
.|.||| ..|.| ..               .|..|||..|.    | . |..    . .  .. .                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-----------------------------------LVLKMATDMALGLLHLHSITI------VHRDLTSQNILLDELGN-----------IKISDFG---
                                     | |. . | |. .|||  .      |||||   |.|..| ..           .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSREKSREGSMTMTN------------------------GGICNPRWRPPELTKN--------LGHYSEKVDVYCFSLVVWEILT-G-EIPFSDL
     |.|.  ...  . ..                        ||    || .||  .          |....| ||. |  ..|||.| | | .  ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DG---------SQASAQVA-------------YAGLRPPIPEYCD--------------PELKLLLTQCWEADPNDRPPFTYIVNKL
.           .   ..                ..|.| |..|               .|. .|..|||..||.||| |. ....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase DPYK2.AA S_TKc 853-1113 26 1.3e-58 201.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 853-1113
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

IQFIQKVGEGAFSEVWEGWWKG--IHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACY-KPACIITEYMAG--GSLYNILHNPNSSTPKV
 ....|.|.|||..|. ...|.   .||||..|         |...||.| ||| .| ||| ...... .  ....||. |  |.|. .... ..  ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

KYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGICNPRWRPPELTKNLGHYSE-KVDVYCFSLVVW
...   . ...  ....| ..||  |.||||  .||||||  .|||.||||.|.          .  .  | ...||.     .|.  |.|.. .  ...
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

EILTGEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVN-----KLKEIS
| |.|. ||.         |. .  ..       .||.| .. .|.. ||..||    . .     |. .  
EMLCGYPPFP-------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DPYK2.AA CZAK 853-1109 35 2.7e-57 196.68 In-house 1-279 (279) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-279/279
Sequence Identity: 35% (102 aa)

IQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFK----ERFIREVQNLKKGNHQNIVMFIGACYKPA----CIITEYMAGGSLYNILHNPNSST
 .| | .|.| | ||  . |.|  ||||..  .   .       . | .||  . |  | |.|.|.|||        ||..|.| ||||   |      |
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLL------T

PKVKYSFP---LVLKMATDMALGLLHLHS----ITIVHRDLTSQNILLDELGN-------------IKISDFGLSREKSREGS-MTMTNGGICNPRWRPP
 .  |  .   | ..|| | | |   ||       |.||||.|.|||||.                 ||.|||||||.   .. || | | .|   |  |
DHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLC---WMAP

ELTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELK---LLLTQCWEADPNDRPPFTYIVNKL
|  |    |.|||||| | ...|.|.|.. |  ..         ||   |||.|   ||  |    |...||.  |  || |  |.  |
ECFKG-ENYTEKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase DPYK2.AA Pkinase 853-1109 24 9.6e-55 192.99 Pfam 1-293 (293) Show / Hide 
Range on Protein: 853-1109
Range on HMM: 1-293/293
Sequence Identity: 24% (72 aa)

IQFIQKVGEGAFSEVWEGWWKGIH--VAIKKLKIIGDEEQFKERFIR--EVQNLKKGNHQNIVMFIGACY--KPACIITEYMAGG----SLYNILHNPNS
.....|.|.|.|..|... .||    ||.|..|  ......... .|  |.| .|. || ||| ......  .  ....||. ||    .|. ...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

STPKVKY--SFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNI----KISDFGLSREKSREGSMTMTNGGICNPRWRPPELTKNLGHYSEKV
   . ..  |   . .... .. || ..||  |.|||| ..|||.|. |.|    ||.||||.. .. . . . ...  . |....||. .   .|. ||
-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYCFSLVVWEILTGEIPFSDL------DGSQASAQVAYAGLRPPIPEYCD-------------------PELKLLLTQCWEADPNDRPPFTYIVNK--L
|.. . ....| |.|. ||..       |  |  ... .. |. ..|. |.                   .|.| ... |.. ||..|| .. |..   .
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF