Gene Gdt1 (Slime mold)

Gdt1

Species: Slime mold
Alias: Gdt1, gdtA, DdisK212, DDB0215003
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Gdt

Sequence

Name Sequence Type Origin Length Description Download
Gdt1.AA Protein None 1661 None Fasta, JSON
Gdt1.kin_dom Protein Kinase Domain None 139 None Fasta, JSON

Protein domain

Protein domains of Gdt1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Gdt1.AA Gdt 1372-1535 33 1.1e-84 287.68 In-house 1-218 (289) Show / Hide 
Range on Protein: 1372-1535
Range on HMM: 1-218/289
Sequence Identity: 33% (74 aa)

IHFQELIEKYSWEILYRGTVGDKNALLKLIKLKTKN--------CEEAYRELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPLGSLDYIISKKK----
| | |..   .  . |.|   .   ..|..|....|        |.|.|||..|.|..|||||...||||......|...||.|.|||.|.|..||    
IDFKEYCSQGTFGMVYKGIWRSSQVAVKMFKHHYVNYTKTYSQSCDEIYREMDILSKIKHQNIVSFIGCVHFSSHHCIVTEYCPRGSLGYYIHQKKNQKK

------------------------LKMSITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTNENAEVCAKVLDLTSSKTIKGLACN---------
                        .|||..|||||.||.||||.||.|..||...|...||....||||.|||||..|...||.|....|.         
SNTNTITNTITNTNTNTNTSTSTSIKMSMIQKIRIMIDIAKGCQFLHQNGIIHRDLKPDNILIFSTNENSEVCAKICDFGTSKEINEFHCKNTNCGTMNY

---------NYIERVDTP
         ||....|..
MSNEIFEGENYQKSTDVY
Kinase Gdt1.AA TKL 1406-1535 21 5.9e-24 83.15 In-house 67-237 (364) Show / Hide 
Range on Protein: 1406-1535
Range on HMM: 67-237/364
Sequence Identity: 21% (38 aa)

KNCEEAYRELNIISRLKHQNILPLIGCVISKDY-------------LCLAFEYPPLGS-LDYIISKKKLKMSITQKIRILIDVAKGCKFLQQSS------
.....  .|....|||.|.||....|.... ..             ||.  || | || |.|..        . |..|. .|.|.|. .| ..       
WFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTK

--IIQKTLRARNIFLYDT---------NENAEVCAKVLDLTSSKTIKGLACNNYIE------------------RVDTP
  ||   |  .||.. .          |.||..|.|. |.  |.....   .| ..                  .. ||
PPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTP
Kinase Gdt1.AA LRRK 1413-1513 32 2.6e-15 50.63 In-house 173-288 (351) Show / Hide 
Range on Protein: 1413-1513
Range on HMM: 173-288/351
Sequence Identity: 32% (38 aa)

RELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPLGSLDYIISKKK---L-----KMSITQKIRILIDVAKGCKFLQQSS--IIQKTLRARNIFLYDTN
.|. |.|.|.| ||..|.|  .. . ||.. ||.|.|.|.  ...||   .     ..| . |..| ...||| ..|. ..  ||   |.  ||.|   .
HEVWIMSHLNHPNIVSLKG--FCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSP

EN-------AEVCAKVLD
.|       |.||||. |
QNHSPNYPNAHVCAKIAD
Kinase Gdt1.AA TKL-Unique 1412-1513 24 8.5e-15 48.77 In-house 43-160 (290) Show / Hide 
Range on Protein: 1412-1513
Range on HMM: 43-160/290
Sequence Identity: 24% (29 aa)

YRELNIISRLK-HQNILPLIGCVI----SKDYLCLAFEYPPLGSLDYIIS---------KKKLKMSITQKIRILIDVAKGCKFLQQSS--IIQKTLRARN
..|.|....|. | ||. ..|  .    .  ..|.  || |.|||.  ..         ....|..  |.... ||.|.|. .|  ..  ||  .|. .|
ENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSN

IFLYDTNENAEVCAKVLD
. .   .  ||. .|. |
FLVDNNSNIAEWNIKICD
Kinase Gdt1.AA TK 1399-1498 10 4.1e-13 39.54 In-house 58-273 (486) Show / Hide 
Range on Protein: 1399-1498
Range on HMM: 58-273/486
Sequence Identity: 10% (23 aa)

KLIKLKTKNCEEAYRE---------------LNIISRLK-----HQNILPLIGCVISK------------DYLCLAFEYPPLGS----LDYIISKKKLK-
| .|... . .|. ..               ..... ..     |.||. |.|..  .              ...  || |.|.    |.    |.. | 
KMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKF

--------------------------------------------------------------------------MSITQKIRILIDVAKGCKFLQQS---
                                                                          ..  |.. .  ..|.|. .| .    
QHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE

---SIIQKTLRARNIFL
    ..   | |||. .
FIQNFVHRDLAARNCLV
Kinase Gdt1.AA Pkinase 1398-1468 22 6.2e-11 39.75 Pfam 29-113 (293) Show / Hide 
Range on Protein: 1398-1468
Range on HMM: 29-113/293
Sequence Identity: 22% (19 aa)

LKLIKLKTKNCEEAYR-----ELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPLG----SLDYIIS---KKKL--KMSITQKI
.| ||........ ..     |. |  ||.| ||. |.... .||.... .|| . |    .|  .||   ....   .   ...
VKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFY
Kinase Gdt1.AA Pkinase_Tyr 1413-1502 26 9.5e-11 37.02 Pfam 52-148 (270) Show / Hide 
Range on Protein: 1413-1502
Range on HMM: 52-148/270
Sequence Identity: 26% (26 aa)

RELNIISRL-KHQNILPLIGCVI-SKDY--LCLAFEYPPLGSLDYIISKK---KLKMSITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTN
||..| . | .|.||. |.|...  ..   ... .|| |.|.|.    |.   | . .. ... . ...|||. .| .  .|   |.|||. . ..|
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN
Kinase Gdt1.AA TK-Unique 1413-1498 21 1.5e-10 32.67 In-house 52-166 (294) Show / Hide 
Range on Protein: 1413-1498
Range on HMM: 52-166/294
Sequence Identity: 21% (25 aa)

RELNIISRLK-HQNILPLIGCVISKD-YLCLAFEYPPLGSLDYIISKKK-----------LK--------------MSITQKIRILIDVAKGCKFLQQ--
.|... . |. |.||. ..|| ...|   ....|| | |.|.  . ...           ||               |  . .......|.| ..|..  
KEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQR

SSIIQKTLRARNIFL
  |....| |||..|
KKIVHRDLCARNVLL
Kinase Gdt1.AA S_TKc 1372-1657 14 1.4e-09 -36.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 1372-1657
Range on HMM: 1-231/231
Sequence Identity: 14% (47 aa)

IHFQELIEKYSWEILYRGTVGD--KNALLKLIKLKTKNCEEAYRELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPL--GSLDYIISKKKLK-----M
 .. ..| | .    |...  .  .   .| ||      | ..||..| .. .| ||  |...  . |.|.. .|| .   |.|  .| |.. .     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTNENAEVCAKVLDLTSSKTIKGLACNNYIERVDTPINLTREISIIRDPKQNNDFNNSNNSNN
.  .  ...  .... ... .  ||   |   ||.| .       . |. |  ... .                                          
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------------------------------------------

NNNNNNNNNNNNNNNSNNSNNSSSL------------KYNI-----HSFAVLSYELLIDEILVGDTRKFGQEKPSIGLDKIDPNIKNFIHKCWN--PIDG
                      ...            .|.       |. .. ||.|  . .        .    ||    .|  |.|| ||..  | . 
----------------------TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----SPEAKDFIRKCLQKDPEKR

FTFNEILK-----TLKDFI
 |  |.|.      .  ..
PTA-EALQDEWDIKCHPWF
Kinase Gdt1.AA TyrKc 1372-1653 13 2.3e-09 -71.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 1372-1653
Range on HMM: 1-280/280
Sequence Identity: 13% (48 aa)

IHFQELIEKYSWEILYRGTVGDKNALLKLIKLKTKNCEEAYRELNIISRL--KHQNILPLIGCVISK-------DYLCLAFEYPPLGSLDYIISKKKLKM
|.. . .      . |.||    .   | .|  .   |. .||..| ..|  .|.||. |.|.....       . |.. .|| |.|.|.  . |.. | 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

SITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTNENAEVCAKVLDLTSSKTIKGLACNNYIE----------RV----DTP-------------
.  ... . ...|.|. .| .  .|   | |||. . . .     ..|. |        ||. . | .          |.    ..              
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDF-------GLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

------------------------------------INLTREISIIRDPKQNNDFNN----SNNSNNNNNNNNNNNNNNNNNSNNSNNSSSLKYNIHSFA
                                    .. .. |  ... .      |    |                                      
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------------

VLSYELLIDEILVGDTRKFGQEKPSIGLDKIDPNIKNFIHKCWNP--IDGFTFNEILKTL
                        .       . . . . .||.    |  ||.|| . .
------------------------F---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Gdt1.AA ULK 1413-1487 24 6.2e-09 27.9 In-house 59-148 (324) Show / Hide 
Range on Protein: 1413-1487
Range on HMM: 59-148/324
Sequence Identity: 24% (22 aa)

RELNIISRLK---HQN--ILPLIGCVISK--DYLCLAFEYPPLGSLDYIISKKKL--------KMSITQKIRILIDVAKGCKFLQQSSII
.| .|.  ||   |.|  |  |. .  ..  ..... .|| . | |. .| |.|         . |  . | .... . |.|.|..  ||
NEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNII
Kinase Gdt1.AA ULK 1413-1487 23 8.6e-08 23.38 In-house 59-152 (329) Show / Hide 
Range on Protein: 1413-1487
Range on HMM: 59-152/329
Sequence Identity: 23% (22 aa)

RELNIISRLK--------HQNILPLIGCVISK--DYLCLAFEYPPLGSLDYIISKKKL---------KMSITQKIRILIDVAKGCKFLQQSSII
.|  |. .||        |.||  |. .  ..  ... . .|| . | |. .|.|.|          . |  . | .... . |.|.|..  ||
NEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNII
Kinase Gdt1.AA TESK 1413-1504 28 9.4e-08 20.09 In-house 42-133 (292) Show / Hide 
Range on Protein: 1413-1504
Range on HMM: 42-133/292
Sequence Identity: 28% (26 aa)

RELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPLGSLDYIISKKKLKMSITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTNEN
||.  . .|.| |||   |  .    |    ||   |.|. . . ..| .| ||||.  .|.|.| ..| .  .    |  .|.   . ..|
REVQLMNKLQHPNILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNN
Kinase Gdt1.AA CAMKL 1412-1468 20 2.6e-07 19.21 In-house 60-132 (297) Show / Hide 
Range on Protein: 1412-1468
Range on HMM: 60-132/297
Sequence Identity: 20% (15 aa)

YRELNIISRLK---HQNILPLIGCVISKDY------LCLAFEYPPLG---SLDYIISK----KKLKMSITQKI
.|| .| ..|.   |.||  |  ..  ...      ..|  || . |    .|||...    .... . ....
RREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRY
Kinase Gdt1.AA Gdt 1619-1653 39 1e-06 18.71 In-house 252-289 (289) Show / Hide 
Range on Protein: 1619-1653
Range on HMM: 252-289/289
Sequence Identity: 39% (15 aa)

PSIGLDKIDP-NIKNFIHKCWNP--IDGFTFNEILKTL
|. ..|..|   |.| |  |||.      || || | |
PTLDQDIFDDNDIRNIIECCWNKNPHKRPTFDEISKHL
Kinase Gdt1.AA LRRK 1645-1655 36 0.069192 2.44 In-house 341-351 (351) Show / Hide 
Range on Protein: 1645-1655
Range on HMM: 341-351/351
Sequence Identity: 36% (4 aa)

TFNEILKTLKD
.|..|.|.|..
HFSQIVKRLSQ
Kinase Gdt1.AA Gdt 1593-1606 50 0.145981 1.13 In-house 219-232 (289) Show / Hide 
Range on Protein: 1593-1606
Range on HMM: 219-232/289
Sequence Identity: 50% (7 aa)

SFAVLSYELLIDEI
||..| ||..| .|
SFGILFYEMMIERI
Kinase Gdt1.AA TKL 1645-1653 66 0.21288 0.81 In-house 356-364 (364) Show / Hide 
Range on Protein: 1645-1653
Range on HMM: 356-364/364
Sequence Identity: 66% (6 aa)

TFNEILKTL
.|.||||.|
SFQEILKRL