Gene KinX (Slime mold)

KinX

Species: Slime mold
Alias: DdisK225, DDB0191487, DdKinX, KinX
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: LISK
Subfamily: LISK-DD1

Sequence

Name Sequence Type Origin Length Description Download
KinX.AA Protein None 1094 None Fasta, JSON
KinX.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of KinX.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase KinX.AA LISK-DD1 27-274 52 3.1e-185 621.66 In-house 1-290 (290) Show / Hide 
Range on Protein: 27-274
Range on HMM: 1-290/290
Sequence Identity: 52% (153 aa)

EIGSGGFGKVFKGEYLGAPVAIKKIHILPDDPNRVDLEKFLNREIETIKL---FTHPNVIQFVGISEN-------------NGILFIVTELIEGGDLQYY
|||.|.||||.||.|.|.||||||||..|.|||..|..||..|||...|    ..|||..||.||.|.             ...|.||||.||||||..|
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY

LKN------------QSIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKN----WKIKVCDFGFARIVEED----NNKSMTICGTDNWMSP
|||            ..|..||.||..||||...||.|||||.|.||||||.|.|||.|    |.||||||||||..|..    ||..||||||||||.|
LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTICGTDNWMAP

EMITGLDYDERSDIFSFGIVLLEIISRVKPAPYMRDAS----FGLAEDIVRNQLIPTD--CPESLIDLTFNCCSVDPNNRPSFKEISQTL
|.|.|..||...|.||||.||||.|.|.||...|...|    |.......|.|.||.|  ||....||...||..|||||||||||.|||
EVILGMSYDWSCDVFSFGMVLLELITRKKPDKRMWQRSPMNCFDIDQEEFRQQKIPKDNDCPREFMDLCMWCCKYDPNNRPSFKEIVQTL
Kinase KinX.AA LISK 27-274 46 4.1e-168 550.5 In-house 1-296 (296) Show / Hide 
Range on Protein: 27-274
Range on HMM: 1-296/296
Sequence Identity: 46% (137 aa)

EIGSGGFGKVFKGEYL--GAPVAIKKIHILPDDPNRVDLEKFLNREIETIKLFTHPNVIQFVGISEN-NGILFIVTELIEGGDLQYYLKN---QSIDLPW
|||.|.||||.||...  | ..|||.||..|.|||. ...||..||....|...|||..||.|.... .| |.||||.|.||||..|||.   ..|.|||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

FLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKN----WKIKVCDFGFARIVEEDN----------------------------------NKSMTIC
..| .||||....||||||. |.||||||.|.||..|    |.||||||||||.....|                                  ...||||
PQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTIC

GTDNWMSPEMITGLDYDERSDIFSFGIVLLEIISRVKPAP--YMRDASFGLAEDI-VRNQLIPTD-CPESLIDLTFNCCSVDPNNRPSFKEISQTL
||..||.|||..| .|||..|.|||||||.||| |||. |  ..|......  |. ...|.|..| ||....||.|.||..||.|||||||| |.|
GTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPDDCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase KinX.AA TKL 28-274 29 5.6e-99 335.14 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-274
Range on HMM: 1-364/364
Sequence Identity: 29% (109 aa)

IGSGGFGKVFKGEYLG----------APVAIKKIHILPDDPNRV-------------------DLEKFLNREIETIKL---FTHPNVIQFVGISENNGI-
|||||||.|.||.. |           .||.||...  || .                     ....|  .|.| |..   . |||..||.|.. ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LFIVTELIEGGDLQYYLKNQSIDLPWFLRANIALDVSLAMSYLHS--------KSIVHRDLKSTNLLVDKNWK--------------I
            |.||.|...||.| .||        | .| ..|||....|.||||        . |.|||||| |.|||.||.              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVCDFGFARIVEEDNN-------------------KSMTICGTDNWMSPEMITGL----------------DYDERSDIFSFGIVLLEIISRVKPAP-YM
|.||||..| .....|                   ..||.||| .||.||.. |                 .|.|..|..|||||| ||..| .|   |.
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

RD---------ASFGLAEDIVRNQLIP------------TDCPESLIDLTFNCCSVDPNNRPSFKEISQTL
 .         . | .. |  .  .||            .|||.|...|   |.. ||..||||.|| ..|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase KinX.AA Dicty4 22-276 37 3.5e-71 236.69 In-house 1-277 (277) Show / Hide 
Range on Protein: 22-276
Range on HMM: 1-277/277
Sequence Identity: 37% (106 aa)

LDFISEIGSGGFGKVFKGEYLGAPVAIKKI--HILPDDPNRVDLEKFLN---REIETIKLFTHPNVIQFVGISE----NNGILFIVTELIEGGDLQYYLK
... ..||.|.||.|.||   |  ||.||   |      | .. |..||   .|..  .   |||...| | .     . | . ||||.   |.|   | 
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNH------NQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLH

N------QSIDLPWFLRAN---IALDVSLAMSYLHS--KSIVHRDLKSTNLLVDKNWKIKVCDFGFAR-IVEEDNNKS--MTICGTDNWMSPEMITGLDY
.      ||| |.| |.     .|.|. . | .||.    |.|||||| ||||||||..||||||... . .. ..|   || |||  ||.||.  .  |
DKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY

DERSDIFSFGIVLLEIISRVKPAPYM--RDASFGLAEDIVRNQL---IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQT--LKQ
.| .| .|||||| ||  |   .||    .  . ... ... .|   || .|| |...|   | . ||..||||.||.|   |  
NEKADVYSFGIVLWEILTRQ--EPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase KinX.AA TKL-Unique 24-217 34 7.1e-67 228.48 In-house 1-224 (290) Show / Hide 
Range on Protein: 24-217
Range on HMM: 1-224/290
Sequence Identity: 34% (79 aa)

FISEIGSGGFGKVFKGEYLGAPVAIKKIHILPDDPNRVDLEKFLNREIETIKLFT-HPNVIQFVGISE----NNGILFIVTELIEGGDLQYYLK------
|.. ||.||.|.|.||.. | |||||..|.   |..   ...| ..|. ..| .  |||. ...|..      .. ..||.| ..|| |  .|       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEF-ENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---NQSIDLPWFLRANIALDVSLAMSYLHSKS--IVHRDLKSTNLLVDKN-----WKIKVCDFGFARIVEEDNNKSMT-I--------CGTDNWMSPEMI
   |....|.. .| ..|.|....| |||...  | ||||||.|.||| |     |.||.||||....   .|... . .        ||. .||.||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TG--LDYDERSDIFSFGIVLLEIISR
..   .|.| ||..|||||| ||..|
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase KinX.AA MLK 22-274 30 6.3e-63 215.36 In-house 1-291 (291) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-291/291
Sequence Identity: 30% (90 aa)

LDFISEIGSGGFGKVFKGEYLGAP-----VAIKKIHILPDDPNRVDLE---KFLNREIETIKLFTHPN----VIQFVGISENNGI-LFIVTELIEGGDLQ
..|   ||||.||||.||.. .       ||.|.... ..    .| .   . ...|..  . . |||    .|||.|.. ...  ..||.| .||| | 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF--DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

YYLKNQS-------------IDLPWFLRANIALDVSLAMSYLHSKS---IVHRDLKSTNLLVD------KNWKIKVCDFGFARIVEEDNNKSMTI-CGTD
 .|....             .  .  . .|.||... .|.||||.    |.|||||| |.|.|      .. . |.|||| .| . .   . |.  .|| 
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTY

NWMSPEMI---TGLDYDERSDIFSFGIVLLEIISRVKPAPYMRDASFGLAEDIVRNQL--IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTL
 ||.||.|    .  |.| .|..|.|.|| |...|  |   . |... ... .. ..   || .|||..  |  .| . ||..||||..| | |
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase KinX.AA Pkinase 22-274 26 3.3e-62 217.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

LDFISEIGSGGFGKVFKGEYLGAP--VAIKKIHILPDDPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGG----DLQYYLK-NQ
. ... ||||.||.|.|.   | .  ||.|.|    ....       | .||.  | . |||.... .. |... . .|.|. |||    ||  |..  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SIDL--PWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKI----KVCDFGFARIV-EEDNNKSMTICGTDNWMSPEMIT-GLDYDERSDIFS
.  .  ..    .... .  .. |.||..|.|||||. |.|.|.|  |    |.||||.|. . .  |   .|.||| ..|.|| |  | .|. ..|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGIVLLEIISRVKPAPYMRD-ASFGLAEDIVRNQLIPT-----DCP-----------------------ESLIDLTFNCCSVDPNNRPSFKEISQT--L
.|..| | ...    |.  .  . . ...... ..|       |.|                       |...|.  .|. .||. ||....| |   .
CGCILYEMLCGR--PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase KinX.AA S_TKc 22-277 27 3.5e-60 207.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-277
Range on HMM: 1-231/231
Sequence Identity: 27% (74 aa)

LDFISEIGSGGFGKVFKGEYLG--APVAIKKIHILPDDPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEG--GDLQYYLKNQSID
 ... .||.|.||||.|.   .    ||||.|.            . . |||.  |   |||.... .. .. . |..|.|...|  |||  |.|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMTICGTDNWMSPEMITGLDYDE-RSDIFSFGIVL
     .|    . ..  . .|. |.||. |.|||||  |.|.|.   ||.||||.||..       .|.||| ..|.||..    |.  ..|. |.|..|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LEIISRVKPAPYMRDASFGLAEDIVRNQLIPTDCPESLIDLTFNCCSVDPNNRPSFKEISQ------TLKQI
 | ...  | |        .  ....        .....|.  .|. .||..||.  |. |          .
YEMLCGYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase KinX.AA Dicty5 22-220 38 1.3e-56 193.4 In-house 1-202 (260) Show / Hide 
Range on Protein: 22-220
Range on HMM: 1-202/260
Sequence Identity: 38% (80 aa)

LDFISEIGSGGFGKVFKGEYLGAPVAIKKIHILPDDP-NRVDLEKFLNREIETIKLFT--HPNVIQFVGISENNGIL-FIVTELIEGGDLQYYLKNQSI-
  |   | ||  |.|..| | |  ||||    .  .     |.. |  ||.  . .|   |||.| . |    |    |.|||..  | |  ||. |   
VSFHDWIASGASGRVYNGIYKGMDVAIK---VYSQENCMCFDWNEF-YREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKT

---DLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMTI-CGTDNWMSPEMITGLDYDERSDIFSFGIVLL
    . .|..  .|.|.  .| .|||..|.|||||| | |. .|||||. |||  | |  || . ||.  || .||..|. .|  |..  |..|||||| 
TGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFV--DNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLW

EIISRVKP
|.. |  |
EMFTRKEP
Kinase KinX.AA TK 22-274 14 9.2e-55 181.63 In-house 1-486 (486) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-486/486
Sequence Identity: 14% (73 aa)

LDFISEIGSGGFG---KVFKGEYLGA---------------------------PVAIKKIHILPDDPNRVDLEKFLN---------REIETIKLFT----
. .. ..|.| ||   .|.|||. |                            |||.| ..   ..  .  .. ...         .| | .|..     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVIQFVGISENN------------GILFIVTELIEGGD----LQYYLKNQSID--------------------------------------------
 |||.....|..  .            . . ||.|. ..||    |. ||.. . .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LPWFLRANIALDVSLAMSYLHSK------SIVHRDLKSTNLLVDKNWK-----------IKVCDFGFA-
                               |.   .  ...... .|.|||||       .|||||   | ||..| .           .|..||| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----RIVEEDNNKSMTICGTDN----------------------------WMSPEMITGLD---------YDERSDIFSFGIVLLEIISRVKPAPYMRD
     .  . ....  .  ..                              ||.|| ...           . . ||..|||... || .. .  .|   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

AS---------FGLAEDIVR---------------NQLIP-TDCPE-------------SLI-DLTFNCCSVDPNNRPSFKEISQTL
 .           . | ..|               ... .  .||.              .. ||   |.. ||. ||.|... . |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase KinX.AA TyrKc 22-274 26 7e-54 186.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-280/280
Sequence Identity: 26% (76 aa)

LDFISEIGSGGFGKVFKGEYLGAPVAIKKIHILPDDPNRVDLEKFLNREIETIKLF--THPNVIQFVGISENN-------GILFIVTELIEGGDLQYYLK
. .. ..|.| ||.|.||..   .||.|...          .| |. ||..  . .   |||.....|.           . |.||.|. ..|||. ||.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-------REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NQSIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEED----NNKSMTIC----GTD-----NWMSPEMITGLDYD
.   .|..    .......  |.||||| ..||||   | ||..|  .|..||| .| ...|     .|..       |..      ||.|| |    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

ERSDIFSFGIVLLEIISRVKPAPYMR-----DASFGLAEDIVRN--QLIPTD--------CPESLIDLTFNCCSVDPNNRPSFKEISQTL
. ||..|||... || .. .. ||          . . |.. .     .| .        ||. . ..   |.  ||..||.|.|| . .
TKSDVWSFGVCMWEIFTYGQQ-PYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase KinX.AA LRRK 22-276 24 8.9e-53 181.65 In-house 1-351 (351) Show / Hide 
Range on Protein: 22-276
Range on HMM: 1-351/351
Sequence Identity: 24% (88 aa)

LDFISEIGSGGFG-KVFKGEYLG----------------------------APVAIKKIHILP--DDPNRVD--------------------------LE
| . ..||.|||| .|..... |                            ..|||||... |   | |  .                          ..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTID-NDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCR

KF--LNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQYYLKNQS--------IDLPWFLRANIALDVSLAMSYLHSKS--IVHRDLKSTNL
.|  . .|.  .  ..|||... .|.. .   | .|.|..  |||. .|.| .        ....| |.  |||... .| ||||..  |.|||||| | 
AFREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNI

LV---D---------KNWKIKVCDFGFARIVEEDNNK-SMTICGTDNWMSPEMITG---LDYDERSDIFSFGIVLLEIISRVKPA-PYMRDAS-FG----
|.   .          . ..|..|||  |.   . ..  ..  |.  ||.|| . .     |.| .|..|||..| |...|     ..... . |.    
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTR---QHHPFDEHDFFDHMQW

--LAEDIVRNQL---IPTD-CPE-----SLIDLTFNCCSVDPNNRPSFKEISQTLKQ
  . ||.. ..|   || . ||.     .. ||   | . ||..||.| .| ..|.|
MEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase KinX.AA Pkinase_Tyr 22-223 29 6.1e-45 152.84 Pfam 1-216 (270) Show / Hide 
Range on Protein: 22-223
Range on HMM: 1-216/270
Sequence Identity: 29% (65 aa)

LDFISEIGSGGFGKVFKGEYL------GAPVAIKKIHILPDDPNRVD--LEKFLNREIETIKLF-THPNVIQFVGISE-NNGI--LFIVTELIEGGDLQY
. |. ..|.| ||.|.||..       . |||.|..   ...    .  .|.|.. |... | .  |||.....|.     .   ..||.|. ..|||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML---KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YLKNQ---SIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIV-EEDNNKSMTICGTD---NWMSPEMITGLDYDERS
||...      |.     ....... .|.||.|| ..||||   | ||..| ..|.|||| || . ..|.  . .  |..    ||.|| |    . . |
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKS

DIFSFGIVLLEIISRVKPAP-Y
|. |||... ||... .  | |
DVWSFGVLMWEIFTYGE-QPTY
Kinase KinX.AA TESK 173-276 42 4.9e-36 110.96 In-house 187-292 (292) Show / Hide 
Range on Protein: 173-276
Range on HMM: 187-292/292
Sequence Identity: 42% (46 aa)

EDNNK-SMTICGTDNWMSPEMITGLDYDERSDIFSFGIVLLEIISRVKPAPYM--RDASFGLAEDIVRNQLIPTDCPESLIDLTFNCCSVDPNNRPSFKE
.|  |  | . |.  ||.||   |  |||..|.||||||| ||| |..  | .  | ..|||  .  .. ..| ||||    |.|.||. ||  ||.|.|
MDSRKEKMAVVGSPYWMAPEVLRGEWYDEKADVFSFGIVLCEIIARIQADPDYMPRTEKFGLDYQAFKE-MCPMDCPEPFLQLAFHCCNMDPKDRPVFHE

ISQTLKQ
| ..|..
ITKHLEW
Kinase KinX.AA TESK 69-171 38 5e-25 75.6 In-house 42-148 (292) Show / Hide 
Range on Protein: 69-171
Range on HMM: 42-148/292
Sequence Identity: 38% (41 aa)

REIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQYYLKNQSIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVD----KNWKIKVCD
||.. .    |||.. | |.   .| |  .|| | || |   | .... |.|  . . |.|.   ||||||| . |||| | | ||     . ..  | |
REVQLMNKLQHPNILRFMGVCVHQGQLHALTEYINGGCLEQLLADSELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGD

FGFARIV
|| ||..
FGLARVL
Kinase KinX.AA TKL-Unique 241-274 47 7.9e-08 23.88 In-house 257-290 (290) Show / Hide 
Range on Protein: 241-274
Range on HMM: 257-290/290
Sequence Identity: 47% (16 aa)

IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTL
||..||... ||   |.  || .|||| ||   |
IPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase KinX.AA Dicty5 241-278 44 5e-07 20.23 In-house 223-260 (260) Show / Hide 
Range on Protein: 241-278
Range on HMM: 223-260/260
Sequence Identity: 44% (17 aa)

IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIK
|| ||| .   |   |    | |||||||| .....| 
IPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase KinX.AA Pkinase_Tyr 241-274 41 7e-06 20.59 Pfam 237-270 (270) Show / Hide 
Range on Protein: 241-274
Range on HMM: 237-270/270
Sequence Identity: 41% (14 aa)

IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTL
.| .||. . ||   |   ||..||.|.|| . |
CPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL