Gene Rck1 (Slime mold)

Rck1

Species: Slime mold
Alias: DdisK210, Rck1, DDB0214828, rckA
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Dicty5

Sequence

Name Sequence Type Origin Length Description Download
Rck1.AA Protein None 1125 None Fasta, JSON
Rck1.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of Rck1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Rck1.AA Dicty5 842-1093 65 1.9e-207 695.47 In-house 1-260 (260) Show / Hide 
Range on Protein: 842-1093
Range on HMM: 1-260/260
Sequence Identity: 65% (170 aa)

VSIHKWIASGSSGRVYNGQYKGKDVAIKVLGPEVCVHFDLNEFKREVALMSIFK--HDNLARCLGAGQYDDKY-FHLTEYCHNGSLFSYLRDQRN----N
||.|.|||||.|||||||.|||.||||||...|.|..||.|||.|||..||||.  |.|..||.||.||.||| ||.||||||||||.||.|||.    .
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

ISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIVDFGTSR-VANKYNMTTHVGTQAWMAPEIFTSRTYTNKVDVYSYAIILFEIFTRK
|...|.||.|..||..||.||||.||||||||||.|.|...||||.|||||| |.|.|.||.|||||.|||.|.|....|..|.||||..|.|.|.||||
IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRK

SAYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYLESII
..||...|.|||.||||||||..|||..|.|||.|||||||||.|||||..|..|.||||
EPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase Rck1.AA TKL 848-1089 26 5.9e-96 325.09 In-house 1-364 (364) Show / Hide 
Range on Protein: 848-1089
Range on HMM: 1-364/364
Sequence Identity: 26% (97 aa)

IASGSSGRVYNGQYKG----------KDVAIKVLGPEVCVHFDLNE-----------------------FKREVALMSIFK--HDNLARCLGAGQYDDK-
| ||..| || |...|          ||||.|..  . .  |..|.                       |..|. .|.. .  |.|. ...|. .. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YFHLTEYCHNGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMS--------IIHRDLKSMNILLTKRLK--------------I
            ..  .|||..|||..||        . ||...||.||||| |||||         |||||||| |||. . ..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIVDFGTSRVANKYNMTTH---------------------VGTQAWMAPEIFTSR----------------TYTNKVDVYSYAIILFEIFTRKSAYDENA
|| |||.||. .. .  ..                     .|| .|||||..                   .|. |.||||..|.|.||.||.  |... 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

N----------INIPNMVMKGERPELP------------KDMQTSISNIIKKCWQQKPSNRPSFIKIVAYL
.          . .   . ||.||..|            .|. .|.......||...|..|||| .|. .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Rck1.AA TKL-Unique 844-1089 32 1.6e-82 280.44 In-house 1-290 (290) Show / Hide 
Range on Protein: 844-1089
Range on HMM: 1-290/290
Sequence Identity: 32% (93 aa)

IHKWIASGSSGRVYNGQYKGKDVAIKVLGPEVCVHFD-LNEFKREVALMSIFK-HDNLARCLGAGQ----YDDKYFHLTEYCHNGSLFSYLR--------
. . | .|..|.|| | ..|..||||.. |.  .... . ||..|| .|. .. |.|. .. |.      |  ...  .|||  ||| ..|         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-DQRNNISFGQRLHFALGIARGMRYLHSMS--IIHRDLKSMNILLTKR-----LKIKIVDFGTSRVAN-----KYNMT------THVGTQAWMAPEIFTS
  . ..... ||...|. ||.|| |||. .  |||||||| |.|.. .     ..|||.|||.|....     ..|.       | .|.  |||||....
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--RTYTNKVDVYSYAIILFEIFTRKS------AYDENANINIPNMVMK---GERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYL
   .|..|.||||..|.| ||.|||        |.. . . .  || .   . ||..| ..  .....|..|| . ||.||||. |. .|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase Rck1.AA MLK 842-1089 32 2e-81 276.84 In-house 1-291 (291) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-291/291
Sequence Identity: 32% (95 aa)

VSIHKWIASGSSGRVYNGQYKGKD-----VAIKVLG--PEVCVHFD---LNEFKREVALMSIFKHDN----LARCLGAGQYDDK-YFHLTEYCHNGSLFS
  .|.|| |||.| |. |....||     ||.|     .. ..        .|..|. . .|..| |      . .|. . . . .. ..||| .|||..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

YLRDQRN-------------NISFGQRLHFALGIARGMRYLHSMS---IIHRDLKSMNILLT------KRLKIKIVDFGTSRVANKY--NMTTHVGTQAW
.|...|.             ...... . .|| .|||| |||||    |||||||| |||..      . .. || ||||||  ..   ||.   || ||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

MAPEIF---TSRTYTNKVDVYSYAIILFEIFTRKSAYD-ENANINI-PNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYL
||||..    . .|. |.||.|....| |..||.  |. .. .. |   ....|.|| .|..   .... .|.||.|.|..||||  || .|
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase Rck1.AA Dicty4 842-1091 34 1.2e-74 248.37 In-house 1-277 (277) Show / Hide 
Range on Protein: 842-1091
Range on HMM: 1-277/277
Sequence Identity: 34% (95 aa)

VSIHKWIASGSSGRVYNGQYKGKDVAIKVL--GPEVCVHFDLNEFKREVALMSIFKHDNLARCLGAGQ----YDDKYFHLTEYCHNGSLFSYLRD-----
  | . | .|| | || |  .||.||.|.|    ..   . ||||..||..|.   | |.  ..||         |    |||.. |.|.| |.|     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-QRNNISFGQRLH---FALGIARGMRYLHS--MSIIHRDLKSMNILLTKRLKIKIVDFGTSR----VANKYN-MTTHVGTQAWMAPEIFTSRTYTNKVDV
 |.  .... ..     |. .|||| .||.    |||||||| |.|  | ...|. ||| |.    . ..   ..| .|| .|||||.  .. |. |.||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSYAIILFEIFTRKSAYD---ENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAY--LES
||..|.|.||.||.  |     .  . .   . |..||..|..  .|..  |..||   |..||||  |. .  ||.
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase Rck1.AA HH498 842-1089 33 4.9e-66 208.22 In-house 1-284 (284) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-284/284
Sequence Identity: 33% (96 aa)

VSIHKWIASGSSGRVYNGQYKGKDVAIK-VLGPEVCVHFD-----LNEFKREVALMSIFKHDNLARCLGAGQYDDKYFHL-TEYCHNGSLFSYL------
.  |. | ||| | || |.. .| ||.| .     |   |        | ||| .|.   | .  . ..|   | . | . |.|| |||||| |      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

--------RDQR---NNISFGQRLHFALGIARGMRYLHS---MSIIHRDLKSMNILLTKRLKIKIVDFGTSRVANKY---NMTTHVGTQAWMAPEIFT-S
          |.    ...   ..  .. .|.||.|||.     |||||| | |||. .  . .. ||| ||  .     |||   |   |||||.|. .
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQC

RTYTNKVDVYSYAIILFEIFTRK---SAYDENANINIPNMVMKGERPELPKD----MQTSISNIIKKCWQQKPSNRPSFIKIVAYL
  |. ||||.|||....|..||.   . |   |      |  .  || .|      .  ..||.|  ||.. |.|||.|  ||. |
QKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAA--EMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase Rck1.AA TyrKc 842-1089 28 4.3e-65 223.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-280/280
Sequence Identity: 28% (81 aa)

VSIHKWIASGSSGRVYNGQYKGKDVAIKVLGPEVCVHFDLNEFKREVALMSIF--KHDNLARCLGAGQYD-------DKYFHLTEYCHNGSLFSYLRDQR
..  | . .|  |.|| |..|  .||.|.| ..      . .| ||  .|. .  .|.|. |..|.   .       . .. ..||. .|.| .|||. |
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIVDFGTSRVANKY-------NMTTH---VGTQ-----AWMAPEIFTSRTYTNKV
....  . |.|.. ||.||.||||. .|||||   |.|..... .|| ||| ||    .        . ..    |.       ||||| .  ...| | 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVYSYAIILFEIFTR-KSAYDE-----NANINIPNMVMKGERPELPKD--------MQTSISNIIKKCWQQKPSNRPSFIKIVAYL
||.|. . ..||||. .. | .       |. . . |..|.|.. |..        . . . .|.|.||. .|..||.|  |. ..
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Rck1.AA Dicty4-Unclassified 842-1089 35 7.5e-64 217.56 In-house 1-263 (263) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-263/263
Sequence Identity: 35% (94 aa)

VSIHKWIASGSSGRVYNGQYKGKDVAIKVLGPEVCVHFD---LNEFKREVALMSIFKHDNLARCLGAGQYD----DKYFHLTEYCHNGSLFSYLR----D
. | . |  |   .|. |  ||||||.| .  |    |    . .||.||...    | || .| |.          .   .|  | | ||        .
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFN-ENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

QRNNISFGQ--RLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIVDFGTSRVA-NKYNMTTHVGTQAWMAPEIFTSRTYTNKVDVYSYAIILF
|   |.      . .|. ||.|| .||.  .||||.|| |||. |   ||| ||| |||  . .||||  || .| .||.     |. | ||||||..|.
QQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLY

EIFTRKSAYDENA-NINIPNMVM-KGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYL
|  |    | |    .|.   |  |. ||..|      ..  || ||   |  ||.. .|. ||
ELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase Rck1.AA Pkinase_Tyr 842-1089 29 1.9e-62 212.09 Pfam 1-270 (270) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-270/270
Sequence Identity: 29% (81 aa)

VSIHKWIASGSSGRVYNGQYK------GKDVAIKVLGPEVCVHFD--LNEFKREVALMSIF-KHDNLARCLGAGQ-YDDK--YFHLTEYCHNGSLFSYLR
... | . .|. |.|| | .|      . .||.|.| .| . | .  . .| ||...|. . .|.|. |..|.    ..   ..  .||. .|.| .|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DQ---RNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIVDFGTSRVA---NKYNMTTHVGTQ---AWMAPEIFTSRTYTNKVDVY
..   .....  . |.... ||.|| ||.|. .|||||   |.|.|. ...|| ||| .|       | .... |.     ||||| .  . .| | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYAIILFEIFT--RKSAYDENANINIPNMV-MKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYL
|. . ..||||  .. .| .  |  . ...  .|.| . |..    | ...|.||...|..||.|  |.  |
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Rck1.AA TK 3-1089 4 2.4e-57 190.47 In-house 82-486 (486) Show / Hide 
Range on Protein: 3-1089
Range on HMM: 82-486/486
Sequence Identity: 4% (64 aa)

TSKDSSNSNSNNNNNNNNNNNNNNNNNNGLNGTYSSKSLSPPTSPKQMSGNSIISNSTGNLSSGSGSGSSSGGNKKFINRSFNTFIDFIKKPARRNSKAH
.                                                                                                   
G---------------------------------------------------------------------------------------------------

NTPPPYPEVDTGFGYFLELDSKPPKPFDEKDDPIHNSTGSTDSWEGDLNSSGGGGKQPQQTQQQSSGENLNNSSDRNNNSNENNQIVDDNSNVFNKGVVV
                                                                                                    
----------------------------------------------------------------------------------------------------

QTVPMTEIGLFPVSLMMAQQRAEHPINVEDIESDVQTCSIPNSKPLYSSLGCSTNSSNSGSSISAPNITFQSFGISPVNNNNNNNNNSNNNSNSNSNSNS
                                                                                                    
----------------------------------------------------------------------------------------------------

NSNNNNNNNNNNNNNNNNNNNNNNNNNSTVNSNNSSLNNSPRYLNSSSSPRSMQHLSSKITTTTTTTTTTTTTTSDDNNGNTNNNISNNNNIINNSNNNS
                                                                                                    
----------------------------------------------------------------------------------------------------

NSNNNNNNNINNTNHKFKTMEKYFSSKENFPIPFPKLKDELGVIIENSSNKGYVGGNKGSEDRRKKIEQKKKQVPAPEMKATKEKFIETITDPTTLNSFR
                                                                                                    
----------------------------------------------------------------------------------------------------

SFMENTQSNENLEFFLEVKRFNTIQDQVLLKHTCDDIWRRFFDDLAVTQLCVESSLKKLINNRRENPTHSMFNEVLDLLLDDIVCDAFRNYISSPFNPEW
                                                                                                    
----------------------------------------------------------------------------------------------------

KSEFKKKFTNNTYSTTTQPINNFNNTNNNNNNNCSTPPNNYSSSPIKQSNINNNNNNASSSNIASSSNVNNNNNNSNGSNTSSSHHRERLDNIKGNRERV
                                                                                                    
----------------------------------------------------------------------------------------------------

DSNGKERSIDNKDILSLLESNLSNHSNSSSNSNGKDKDKDKDKNENTTDNSNNNNNSNNNLNNLIIKNNFNNILQSPQIVSKINEIFKDSNNSQLSISIT
                                                                                                    
----------------------------------------------------------------------------------------------------

LDNDEDPTIFHLDESDMESLIEEVVKDNISVHTEISYSDVSIHKWIASGSSGRVYNGQYKGKDVAIKVLGPEVCVHFDLNEFKREVALMSIFK-----HD
                                                                              . .| .|.. |....     |.
------------------------------------------------------------------------------E-DFLEEAEEMKMMCHSLGHHP

NLARCLGAGQYDDK------------YFHLTEYCHNGS----LFSYLRDQRNN-----------------------------------------------
|. |..|.   ..             .  ..||...|.    | .|||. |..                                               
NIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

----------------------------ISFGQRLHFALGIARGMRYLHSM------SIIHRDLKSMNILLTKRLK-----------IKIVDFG------
                            ..  |.| ... ||.||.||||.       ..||||   |.|......           .|| |||      
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGS

--TSRVANKYNMTTHVGTQA----------------------------WMAPEIFTSRT---------YTNKVDVYSYAIILFEIFT--RKSAYDENAN-
   .|  ..    . ....                             ||||| ...|.         .| | ||.|. . ..||||  ..  | .  | 
GVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQ

--------INIPNMVMK------------GERPELP--KDMQ--------------TSISNIIKKCWQQKPSNRPSFIKIVAYL
          . ... .            |.| ..|  ...               . .  ....||. .|. ||.|  .. .|
DVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Rck1.AA LRRK 916-1091 34 1.9e-56 193.82 In-house 134-351 (351) Show / Hide 
Range on Protein: 916-1091
Range on HMM: 134-351/351
Sequence Identity: 34% (75 aa)

TEYCHNGSLFSYLRDQRNN--------ISFGQRLHFALGIARGMRYLHSMS--IIHRDLKSMNILL---T---------KRLKIKIVDFGTSR--VANKY
.||  .|.| ..|.. ...        || . .|  || ||.||.|||| .  |||||||| ||||   .            ..||.|||.||   . ..
MEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHM

N-MTTHVGTQAWMAPEIFTSR---TYTNKVDVYSYAIILFEIFTRK-SAYDENA-------NINIPNMVMKGERPELPKD-MQT-----SISNIIKKCWQ
    . ||.  ||||||       .|| |||.||...||.|. ||.  ..||         .. | . ...| || .| . .       . .. |..|||
GVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQ

QKPSNRPSFIKIVAYLES
..| .||.|..||  |..
HDPKKRPHFSQIVKRLSQ
Kinase Rck1.AA Pkinase 842-1089 27 1.5e-55 195.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

VSIHKWIASGSSGRVYNGQYKGKD--VAIKVLGPEVCVHFDLNEFKR--EVALMSIFKHDNLARCLGAGQYDDKYFHLTEYCHNG----SLFSYLR-DQR
  |.. | |||.|.|| .. ||    ||.|..  .   .  . .  |  |...|  ..|.|  |.... ...|..   .||| .|    .||.|.. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NNI--SFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKI----KIVDFGTSR---VANKYNMTTHVGTQAWMAPEIFT-SRTYTNKVDVYSY
...  |  .  .... |.||. |.|||.|||||||. |||. ..  |    || ||| ..     |.  ||| .||  .||||.   .. |. |||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

AIILFEIFTRKSAYDEN----ANINIPNMVMKGERPELPKDMQ-----------------------TSISNIIKKCWQQKPSNRPSFIKIVAY--L
 .||.| ....  ...       ..   |. .  .|.|. | .                        .   .||.|....|. ||..  |.    .
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Rck1.AA LISK 847-1035 31 5.2e-55 177.08 In-house 89-326 (296) Show / Hide 
Range on Protein: 847-1035
Range on HMM: 89-326/296
Sequence Identity: 31% (76 aa)

WIASGSSGRVYNGQYK--GKDVAIKVLGP---EVCVHFDLNEFKREVALMSIFKHDNLARCLGAGQY-DDKYFHLTEYCHNGSLFSYLRDQRN---NISF
 | .|. | || | ..  |...||| .      ..    .  ..|||..|  . | |  .  |.    |.... .|||   | |. ||.|      ... 
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

GQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKR----LKIKIVDFGTSRVANKYN-------------------------------------MTTH
 ||...||.||.||.||||| ||||||||.|.|. ..     .||. |||  |.....|                                     ||  
PQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTI-

VGTQAWMAPEIFTSRTYTNKVDVYSYAIILFEIFTRKSA
.||  |||||. . . |. ..||.|. |.| || ||. |
CGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase Rck1.AA S_TKc 842-1089 26 2.1e-53 184.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 842-1089
Range on HMM: 1-231/231
Sequence Identity: 26% (70 aa)

VSIHKWIASGSSGRVYNGQYKG--KDVAIKVLGPEVCVHFDLNEFKREVALMSIFKHDNLARCLGAGQYDDKYFHLTEYCHN--GSLFSYLRDQRNN---
  |.. | .|. |.|| .. |.  . ||||..          . ..||.....  .|.|. ..... |  |...  .||| .  |.||.|..... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--ISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIVDFGTSRVANKYNMTTHVGTQAWMAPEIFTSRTYTN-KVDVYSYAIILFEIFT
  ..  .  ...  |.... |.||. |||||||  ||||..   ||| ||| .|.      || .||  .||||..    |.  |.|..|  .||.| ..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

RKSAYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVA---------YL
..  ..     ..  |  |            .  ..|.||.|  |..||.  .. .         ..
GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Rck1.AA RGS 487-602 17 2.9e-23 78.76 Pfam 1-124 (124) Show / Hide 
Range on Protein: 487-602
Range on HMM: 1-124/124
Sequence Identity: 17% (22 aa)

KFIETITDPT-TLNSFRSFMENTQSN-ENLEFFLEVKRFNTI----QDQVLLKHTCDDIWRRFF-DDLAVTQL-CVESSLKKLINNRREN--PTHSMFNE
 | . . |.   .. || |.|.. .  ||.|| |....| ..    ..... | .. .|..... .| .  .. ............. |.  ||...|.|
SFHHLCNDQPIGRRLFRQFLESEFCEYENIEFWLACEDFKKMFSDSDEKMHQK-DAREIYNKYIAPDSP-CECHNIDHDTREHCQDNLEQAQPTPDCFDE

VLDLLLDDIVCDAFRNYISSPFNPEW
. .  .. . .|... .. |..  ..
AQRHIYTLMEKDSYPRFLKSDYYQRF
Kinase Rck1.AA LRRK 842-899 15 1e-06 19.38 In-house 66-184 (351) Show / Hide 
Range on Protein: 842-899
Range on HMM: 66-184/351
Sequence Identity: 15% (19 aa)

VSIHKWIASGSSG-RVYNGQYKG----------------------------KDVAIKVLGPEVC----------------------------------VH
. | . | .|..| .|| . ..|                            ..||||..  ...                                   .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW--NRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCC

FDLNEFKREVALMSIFKHDNL
  ..|| .||..|| ..|.|.
RAFREFRHEVWIMSHLNHPNI
Kinase Rck1.AA RGS 487-603 18 8e-06 22.03 SMART 1-121 (121) Show / Hide 
Range on Protein: 487-603
Range on HMM: 1-121/121
Sequence Identity: 18% (22 aa)

KFIETI-TDPTTLNSFRSFMENTQSN--ENLEFFLEVKRFNTIQDQVLLKHTCDDIWRRFFDDLAVT--QLCVESSLKKLINNRRENPTHSMFNEVLDLL
 | . .  ||  .. || |.... .   |||||.|....| ...|   .. .  .|. ....  | .  .. . ..... .... .||.  .|.| ..  
SFHHLCDNDPIGRRYFREFLKQEFCEYKENLEFWLACEEFKKMED-EERRQKAREIYDKYISPNAPCEHCVNIDHHTREQCQQCLCNPHPDCFDEAQRHV

LDDIVCDAFRNYISSPFNPEWK
 .    | .. ...|..  .  
YQLMEKDSYPRFLRSDYYKRYL
Kinase Rck1.AA LISK 1075-1089 60 0.000709 8.25 In-house 282-296 (296) Show / Hide 
Range on Protein: 1075-1089
Range on HMM: 282-296/296
Sequence Identity: 60% (9 aa)

KPSNRPSFIKIVAYL
.|.||||| .||  |
DPKNRPSFKEIVQWL