Gene rk3 (Slime mold)

rk3

Species: Slime mold
Alias: DDB0229964, DdisK200, rk3
External Links: DictyBase Link ,
Annotation:

Classification

Group: TKL
Family: Dicty4
Subfamily: DRK

Sequence

Name Sequence Type Origin Length Description Download
rk3.AA Protein None 749 None Fasta, JSON
rk3.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of rk3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TIG rk3.AA TIG 313-403 27 6.6e-10 35.89 Pfam 2-82 (82) Show / Hide 
Range on Protein: 313-403
Range on HMM: 2-82/82
Sequence Identity: 27% (26 aa)

KVNSVVP-NTAPSTGGETVYFIGEQF-YQSSQIQCKFGTVISTGTYINSTCASCVVPPMLQSNSTTPSDYNVTIQLSEDGGSSFCLNTTFFIY
...|. | .|.|. ||.|.. .|. |  .|  ..|.||..  | ....||   |..||        |. .||..  ..    . . |.| | |
TITSISPNTTGPPSGGTTITITGQNFGNDS-DTKCYFGGTPCTVIWWSSTQIVCTTPPHT------PGTHNVSV-VNG----QWSSNPTTFTY
Kinase rk3.AA DRK 491-748 67 1.4e-227 762.31 In-house 1-258 (258) Show / Hide 
Range on Protein: 491-748
Range on HMM: 1-258/258
Sequence Identity: 67% (175 aa)

IVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHDPSISLDWPRM
|...||||||...|||.|||||..||.|.....|..||.||||...|...|.||||||||||.|||||||.|.|.|||||.||||.||||.||..|||.|
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

KSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRNDPYTEKADVFSFAIVLWEIVTRED
|.|..|.||||.|||||.||.|||||||||||||||..||..|||||||||||...|.|||..|||||||||||||..|||||||.||||||||.|||.|
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQD

PYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLEA
||.||||||.|.|||.|..||..|.........|...||.||||.|||.||...||||
PYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase rk3.AA Dicty4 491-748 54 2.4e-187 628.7 In-house 1-277 (277) Show / Hide 
Range on Protein: 491-748
Range on HMM: 1-277/277
Sequence Identity: 54% (150 aa)

IVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNED-DEDFLNELAQEATIMSQLRHPNICQFLGTCN----NPPEILIVMEYMPLGSLYRILHD-----
|....|||.||..||..|||||..||.||....|.. ||..|||...|..||...||||||.|.|.|.    .|....||.|||| |.||..|||     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-PSISLDWPRMKS---MALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKT-AMTPVGTPCWTAPEVLRNDPYTEKADV
 .||.||||..|.   ||.|.|.|||.||||.|..|||||||||||||...|||..|||||...||| |.|. .||..|||||.||||....||.|||||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

FSFAIVLWEIVTREDPYQ--GMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKR--LEA
.||.||||||.||..|||  .||..|.|..|...||||..|.........||..||..|||.||||.||..|  ||.
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase rk3.AA TKL 497-746 34 9.40000000001e-117 394.18 In-house 1-364 (364) Show / Hide 
Range on Protein: 497-746
Range on HMM: 1-364/364
Sequence Identity: 34% (128 aa)

IGRGSCAEVFTGTWRG----------IIVAIKKAKLLNEDDED------------------------FLNELAQEATIMSQLRHPNICQFLGTCNNPPE-
||.|. .||. |.|||            ||.|| |  |.| ..                        |  .. .|. .||.||||||.||.| |..||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------ILIVMEYMPLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLHCCD------PIVIHRDLKSHNLLVDEHYR--------------V
            . |||||.| |||. .||       |... ..|||||.|||||| ..      | .|||||||.|.||||...              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KISDFGLSTRFKKH-----------------LDKKTAMTPVGTPCWTAPEVLRND----------------PYTEKADVFSFAIVLWEIVTREDPYQGMP
||.|||||......                 . .|| ||..|||.| ||||||..                .|.||.||.||.||||||.||. ||...|
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

TFQIV---------ISVGQHKLRPIVP------------PQVSAPFTRLITECWSEDPQQRPSFQEIVKRL
 ....         . |....||| .|            |..  .. .|...||..||..|||||||.|||
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase rk3.AA TKL-Unique 493-746 41 5.5e-105 355.09 In-house 1-290 (290) Show / Hide 
Range on Protein: 493-746
Range on HMM: 1-290/290
Sequence Identity: 41% (121 aa)

VQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDE-DFLNELAQEATIMSQLR-HPNICQFLGTCN----NPPEILIVMEYMPLGSLYRILH-------
. | ||.|....|. |.|||..||||. .. ||| . ... |.  | ..|. |. |||| .. |.|      ||.  |||||.|.||||  ||       
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--DPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEH-----YRVKISDFGLSTRFKKHLDKKTAM-------TPVGTPCWTAPEVLR
   ... |.. .. .||.|||.||.||| |.| .||||||| |.|||..     ...||.|||||.  .| ..... .       |..|.. | ||||||
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

N--DPYTEKADVFSFAIVLWEIVTRED------PYQGMPTFQIVISVGQ--HKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRL
.  . |.||.||.||.||||||.||.       |||||   |.   | .   ..|| .|.     .. ||..||  ||.|||||.||..||
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase rk3.AA MLK 491-746 36 4.7e-102 345.35 In-house 1-291 (291) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-291/291
Sequence Identity: 36% (108 aa)

IVVQNRIGRGSCAEVFTGTWRGII-----VAIKKAKLLNEDDEDF----LNELAQEATIMSQLRHPN----ICQFLGTCNNPPE-ILIVMEYMPLGSLYR
| ..  || ||  .|. |.||. .     ||.|...   . |         .. .|. . . |.|||    |.||.|.|..||   .|||||.. ||||.
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

ILHD-PS------------ISLDWPRMKSMALDIAKGMNYLHCCDP-IVIHRDLKSHNLLVDE------HYRVKISDFGLSTRFKKHLDKKTAMTPVGTP
.||. .|            .  |   . . ||..|.||.|||. .|  .|||||||||.|.||      |  .||.|||.|. ....   .. |   ||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

CWTAPEVL---RNDPYTEKADVFSFAIVLWEIVTREDPYQ-GMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRL
 | ||||.   |...|.||.||.|...||||..||| ||. ..  ..| . |....||| .|.. .... .|...||..|| .||||..||. |
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase rk3.AA LRRK 491-748 30 4.9e-86 292.13 In-house 1-351 (351) Show / Hide 
Range on Protein: 491-748
Range on HMM: 1-351/351
Sequence Identity: 30% (107 aa)

IVVQNRIGRGSCA-EVFTGTWRG----------------------------IIVAIKKAKLL---------NEDD----------------------EDF
.. .. ||||. . .|. ..|||                              ||||| ..          | ..                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHDPS--------ISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLL
..|. .|..||| |.|||| . .| | .|  . .||||.|.|.||. ||...        ....|      ||.|||||.||| ..| .|||||||.| |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

V---D---------EHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRND---PYTEKADVFSFAIVLWEIVTRE-DPYQGMP---TFQIVIS
.   .         .|. .||.|||.|. | . . .. |.. ||.| | |||..|..    ||||.|..||...|||..||. .|.....    .|  . 
LWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

VGQ---HKLRPIVPPQ-VSA-----PFTRLITECWSEDPQQRPSFQEIVKRLEA
. .    .||| .|.           .  ||..||..||..||.|..|||||. 
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase rk3.AA Dicty4-Unclassified 491-746 35 1.3e-77 264.12 In-house 1-263 (263) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-263/263
Sequence Identity: 35% (97 aa)

IVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDEDFL----NELAQEATIMSQLRHPNICQFLGTCNNP----PEILIVMEYMPLGSLYRILH---
| .   ||.|  ..|  | |.|  ||.||   .||    |      .   |  |.  . |||  .  | | ||      . |||| |. | |  . |   
IQIDQFIGKGHFSKVHKGNWKGKDVAVKK---FNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKP

---DPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVG-TPCWTAPEVLRNDPYTEKADV
   . .|.||      .|.|||.|| .||  .  .||||.|| |.|.| |. .|| |||.|       |    || .. || |..||.|.   |. |.||
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADFGIS----RVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDV

FSFAIVLWEIVTREDPYQGMP-TFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRL
.|.|..|.| .| . |||. .    . .||   |||| .|  .   . .||  ||..||. ||.. .|...|
YSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase rk3.AA HH498 491-746 32 9.5e-76 239.54 In-house 1-284 (284) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-284/284
Sequence Identity: 32% (94 aa)

IVVQNRIGRGSCAEVFTGTWRGIIVAIK--KAKLLNEDDE---DFLNELAQEATIMSQLRHPNICQFLGTC-NNPPEILIVMEYMPLGSLYRIL------
|  .  || ||  .|. |.||. |||.|  .|.   .  .        .  |. ||..| ||.  ||...| . | . .|| .|   |||..||      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

--------HDPS---ISLDWPRMKSMALDIAKGMNYLHC-CDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTP-VGTPCWTAPEVLR
        |      . .| .    ...|.|.||||||    . .||||| ||| |..|  . .. ||| | ||.. .. .. ||   | . | ||||  
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGES-RFVCDMHDDN-MTKQPGNLRWMAPEVFS

-NDPYTEKADVFSFAIVLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQ----VSAPFTRLITECWSEDPQQRPSFQEIVKRL
 .  |..|.||||.|...||. ||| |.           .  |. || .| .    . ..   ||  ||.  |  ||.| .||  |
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase rk3.AA TKL-ciliate2 491-747 39 1.5e-72 241.37 In-house 1-273 (273) Show / Hide 
Range on Protein: 491-747
Range on HMM: 1-273/273
Sequence Identity: 39% (109 aa)

IVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHDPSISLDWPRM
. .||.|  |    ..   || |.||.|| | .  |... . .  .|   |  ||||||  ||| | . |   |.|||   |||. .| . .. | |   
LEIQNKITEGGYGIIYKAKWREIVVAVKKFK-MDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDR

KSMALDIAKGMNYLHCCDPIVIHRDLK--------------------SHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRNDPYT
. .|||||.|. |||  .| .||||||                    | |.|||. .| |..|||  || |      |.   .||  | ||||..   ||
RRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGW-TRVKPQDNYMTNK--IGTYQWMAPEVIKAFYYT

EKADVFSFAIVLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLE
|||||||..|.||||  || || ..    .   | .  ||| .| ..   |. |.  || .. . ||||.||.| ||
EKADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase rk3.AA TK 491-746 19 1e-71 239.46 In-house 1-486 (486) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-486/486
Sequence Identity: 19% (96 aa)

IVVQNRIGRGSCA---EVFTGTWRG---------------------------IIVAIKKAKLL-NEDDEDFLN-------------ELAQEATIMSQ--L
|.. . .|.|      ||. |.|||                           . ||.|  |.  ....|.|.              |.|.|. .|..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHPNICQFLGTCNNP------------PEILIVMEYMPLGS----LYRILHDPSIS--------------------------------------------
.|||| ...| |  .            . ..|||||||.|.    |   |.. .                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LDWPRMKSMALDIAKGMNYLHCCDP----IVIHRDLKSHNLLVDEHYR-----------VKISDFGLST
                               |. ...  |...||.|| ||| .       ..||||  .| ||.|...           .||.||||| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RFKKHLDKKTAMTPVGTPC-------------------------WTAPEVLR---------NDPYTEKADVFSFAIVLWEIVTRE-DPYQGMP
       |   . |  ..... ||..                         |.|||.|.         .  .|.| ||.|| ...|||.|.   || |. 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TFQIVIS------------VG-----------QHKLRPIVPPQVS--------------APFTRLITECWSEDPQQRPSFQEIVKRL
. | |..             |            ...|.  ||. .              . . .|...||..||..||.|......|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase rk3.AA Pkinase 491-746 24 3.2e-70 244.4 Pfam 1-293 (293) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

IVVQNRIGRGSCAEVFTGTWRGI--IVAIKKAKLLNEDDEDFLNELA-QEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLG----SLYRILH-DPS
...  .||.|| ..|. ....|   |||.|. |. .|...   . .  .|. ||  |.||||....... ....| .||||.. |    .|..... . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ISL--DWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRV----KISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLR-NDPYTEKADV
 ..  ..   |.... |..|..|.| .   .||||||. |.|.|... .    ||.||||.  |. .  .  ..|..||| . ||||.| . .|. |.|.
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSFAIVLWEIVTREDPYQGM---PTFQIVISVGQHKLRPIVPPQVS-----------------------APFTRLITECWSEDPQQRPSFQEIVKR--L
.|. ..|.| .... |..|    ..    . . . ...|... . .                        ..  .|. |.  ||..||....|..   .
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase rk3.AA Pkinase_Tyr 491-746 34 4.9e-70 237.83 Pfam 1-270 (270) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-270/270
Sequence Identity: 34% (94 aa)

IVVQNRIGRGSCAEVFTGTWR------GIIVAIKKAKLLNEDDEDFLNELAQEATIMSQL-RHPNICQFLGTCN--NPP-EILIVMEYMPLGSLYRILHD
|.    .|.|.  ||. |||.      .| ||.|. |    ... .. .. .|| ||.|| .|||| ...| |     | .|.|||||||.|.|.  |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

P---SISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRF-----KKHLDKKTAMTPVGTPCWTAPEVLRNDPYTEK
.     .|. ... .|...|||||.||.      |||||   | ||.|   |||.||||.          .  .. .. |.    |.|||....  .|.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPI---KWMAPECINYGKFTTK

ADVFSFAIVLWEIVTRE-DP-YQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRL
 || || ...|||.|.   | |.||. ....  ....  |   |.  ...  .|...|| .||..||.|.||. .|
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase rk3.AA TyrKc 491-746 32 9.2e-65 222.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 491-746
Range on HMM: 1-280/280
Sequence Identity: 32% (95 aa)

IVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDEDFLNELAQEATIMSQL--RHPNICQFLGTCNNP-------PEILIVMEYMPLGSLYRILHDP
|.    .|.|   ||. |||. | ||.|. |         . .. .|| ||..|  .|||| ...| |  .       . ..|||||||.|.|   |...
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

SISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKH--------LDKK----TAM--TPVGTPCWTAPEVLRND
   | .. . |....||.||.|||     .|||||   | ||.| ..|||||||||   . .          .|     .    |.    |.|||...  
RPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI---RWMAPECINYG

PYTEKADVFSFAIVLWEIVTR-EDPYQG-----MPTFQIVISVGQHKLRPIVPP-------QVSAPFTRLITECWSEDPQQRPSFQEIVKRL
 .|.| ||.|| ...||| |. . || |     |. ....  | | . .|. |          ..   .....|| ||| .||.|.||....
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase rk3.AA S_TKc 491-749 24 4.9e-58 200.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 491-749
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

IVVQNRIGRGSCAEVFTGTWRG--IIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPL--GSLYRILHDPSIS--
  . . ||.|. ..|. .....   |||||. |          . . .|  |... .||||....... .  .. .||||..   |.|......      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRNDPYTE-KADVFSFAI
   ..  . ....  |.....|.|     .||||||  |.|.||  ..||.||||....         .| .||| . |||||   .|.  |.|. |. .
RFPFPE-HARFYMYQICCALEYCHSHG--IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVK------RLEAM
.|.| .... |..   . | .. .             | ..  .|  |.  ||..||.  |. .        . .
ILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF