ALK1

Species: Bakers Yeast
Alias: ALK1
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
ALK1.AA Protein Refseq_NP 760 Alk1p [Saccharomyces cerevisiae] Fasta, JSON
ALK1.kin_dom Protein Kinase Domain None 172 None Fasta, JSON

Protein domain

Protein domains of ALK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ALK1.AA DUF3635 649-760 38 4e-64 222.68 Pfam 1-121 (121) Show / Hide
Range on Protein: 649-760
Range on HMM: 1-121/121
Sequence Identity: 38% (47 aa)

LFFLNGKDKSKINEYQYQFEFEIYQSMRILLNM--DASAFEPMTNLYWLYYLSRVLL-KFGDRKLG--KNDANRDKMARVINHLEMNLAVHKRGGQLFKR
..|..||.|||||||||...|.||..||..|..  ..|.|.||||..||.||...|| |.......  ...|.|..|...|||..|..|.||...|.|..
HDFFQGKGKSKINEYQYDYQFDIYRMMRKMLKNPICWSQFHPMTNVLWLHYLIHKLLHKMKFKSICTENTAAMRMYMKKIINHHLMDPARHKHFHQIFMS

LETEDIKNTGDLLKLY----K
.|...|......|...    |
FESASIRHCQHYLFNWVRQMK

Kinase ALK1.AA Haspin 561-732 11 1e-39 138.25 In-house 1-237 (264) Show / Hide
Range on Protein: 561-732
Range on HMM: 1-237/264
Sequence Identity: 11% (27 aa)

LYLYLLFKDHGTPISLISLK--NWKQILKIFWSCA------------------GIIHGLEKNLKFEHRNLTLDNILIDGNGNITIIDFKCSR-LQTPQDD
.. .. ....|...| .  .  .. .|..|.|||                    .|. ..|. |..|||.........|....|....||.. |....|.
NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH

VLYLR---------------LDHPLFFLNGKDKSKINEYQYQFEFEIYQSMRILLN--MDASAFEPMTNLYWLYYLSRV---------------------
. |..               ..|......|................|.. ......  ..  ......|.........                      
YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS

------LLKFGDRKLGKNDANRDKMARVINHLEMNLA
      ...|.....||.......... .........
HGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFW

Kinase ALK1.AA NuaK 607-628 59 5.3e-07 13.88 In-house 122-143 (252) Show / Hide
Range on Protein: 607-628
Range on HMM: 122-143/252
Sequence Identity: 59% (13 aa)

HRNLTLDNILIDGNGNITIIDF
|| | | ||| | |.|. | ||
HRDLKLENILLDQNCNAKIADF

Kinase ALK1.AA MARK 607-628 62 7.9e-07 18.54 In-house 127-150 (262) Show / Hide
Range on Protein: 607-628
Range on HMM: 127-150/262
Sequence Identity: 62% (15 aa)

HRNLTLDNILIDGNG--NITIIDF
|| . ..||||| ||  || ||||
HRDIKPENILIDENGNHNIKIIDF

Kinase ALK1.AA Ciliate-E9 607-628 54 2.2e-05 12.72 In-house 135-156 (298) Show / Hide
Range on Protein: 607-628
Range on HMM: 135-156/298
Sequence Identity: 54% (12 aa)

HRNLTLDNILIDGNGNITIIDF
|| | ..|.||| | |. |.||
HRDLKPENMLIDKNYNMKICDF

Kinase ALK1.AA Ciliate-E2-Unclassified 607-628 52 3.4e-05 13.99 In-house 167-191 (352) Show / Hide
Range on Protein: 607-628
Range on HMM: 167-191/352
Sequence Identity: 52% (13 aa)

HRNLTLDNILIDGNG---NITIIDF
||.....|||.| ||   .| ||||
HRDIKPENILFDNNGKNYYIKIIDF

Kinase ALK1.AA CAMKL 607-628 58 6.8e-05 11.39 In-house 150-173 (297) Show / Hide
Range on Protein: 607-628
Range on HMM: 150-173/297
Sequence Identity: 58% (14 aa)

HRNLTLDNILIDGNG--NITIIDF
|| . ..|||.| ||  || ||||
HRDIKPENILLDENGNNNIKIIDF

Kinase ALK1.AA AGC 602-628 37 0.000143 6.16 In-house 171-199 (395) Show / Hide
Range on Protein: 602-628
Range on HMM: 171-199/395
Sequence Identity: 37% (11 aa)

N-LKFEHRN-LTLDNILIDGNGNITIIDF
. ... ||  | ..|||.| .|.| . ||
SHMGIIHRDYLKPENILLDEDGHIKLTDF

Kinase ALK1.AA Ciliate-E2 607-639 33 0.000211 11.0 In-house 184-211 (365) Show / Hide
Range on Protein: 607-639
Range on HMM: 184-211/365
Sequence Identity: 33% (11 aa)

HRNLTLDNILIDGNGNITIIDFKCSRLQTPQDD
||.. ..|||.     | ||||  |. .... .
HRDIKPENILF-----IKIIDFGLSKKYDDDNQ

Kinase ALK1.AA DDR 602-632 36 0.000419 10.27 In-house 152-184 (306) Show / Hide
Range on Protein: 602-632
Range on HMM: 152-184/306
Sequence Identity: 36% (12 aa)

NLKFEHRNLTLDNILIDGNGNITIIDFK--CSR
.. | || |.  |.|......| | ||    ||
SMNFVHRDLATRNCLVGKEYHIKICDFGTVMSR

Kinase ALK1.AA CAMK 607-628 35 0.000431 8.29 In-house 202-240 (425) Show / Hide
Range on Protein: 607-628
Range on HMM: 202-240/425
Sequence Identity: 35% (14 aa)

HRNLTLDNILIDGN-----------------GNITIIDF
|| | ..|||.| |                 .|| ||||
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF