Gene 15961 (Tetrahymena)

15961

Species: Tetrahymena
Alias: 15961, 742, TTHERM_00320440, 32.m00205, PreTt15961
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
15961.AA Protein None 847 None Fasta, JSON
15961.kin_dom Protein Kinase Domain None 259 None Fasta, JSON
15961.NA RNA None 2544 None Fasta, JSON

Protein domain

Protein domains of 15961.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15961.AA AGC 454-712 27 1.1e-126 329.19 In-house 1-395 (395) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-395/395
Sequence Identity: 27% (109 aa)

FNFHYVIGKGGFGKVWKVDSK------KTKKVYAMKEMSKSK-IITKR--SVNSVMSE------------RQLLSQLK----------NPFLVN-MNFAF
|.|. |||||.||||. |  |       |.|.|||| ..|.. |. |.   |  .|.|            |. |....          .||.|. . ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDREN--LYLVMDLLT---------GG-DLRFHI-G--KHRRFSEVQTRFFIAC-------IMMCLEYLHL-NNIIHRD-IKPENLVMDDSGYLRVTDLG
|| ..  ||.||...          || .| .|. |  | .||.| ..||..|.       | ..|||||  ..||||| .||||...|. |... || |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IARV--------------------------------------WKPEN--------------SQDTSG--TPGYMAPEVMCRQNHGIAVDYFA--VGVIGY
 . .                                      |. .|               .   |  || |||||.     .| |.|. .  .|.. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFMMGRRPYLGRS----------RKEIRDQILAKQ-VQIKKHEIP----------DGWSIEAADFINRMIQRKPMNRLGIN-------GPEEVKNHPWL
|.. |. |. | .          ..|. ..|.  . .. .| ..|          . .| || |.|...... | .||| .       | ||.||||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 15961.AA Ciliate-E2-Unclassified 454-712 30 9.3e-118 397.51 In-house 1-352 (352) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-352/352
Sequence Identity: 30% (107 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVYAMKEMSKSKIITKRSVNSV---------MSERQ-------------LLSQLKNPFLVNMNFAFQDRENLYLVM
......||.||||||.|.  ||.|..||||.|.|..|. .......         | ...             .|.....||.|.| ..|||..|.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DLLTGGDLRFHIGKH-----------------RRFSEVQTR-----FFIACIMMCLEYLHLNN-IIHRDIKPENLVMDDSG---YLRVTDLGIAR-----
... ||||...| |                  ..|.| |..     |..|.|  .||||| .| ||||||||||...|..|   |....|.||..     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------VWKPENSQDTSGTPGYM----APEVMCRQNHG----IAVDYFAVGVIGYEFMMGRRPYLGRSRKE----------------IRDQILA
            .||........|||.||    ||||...||..    ...|....||| ||...|..|. ......                ....|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KQVQIKKHE---IPDGWSIEAADFINRMIQRKPMNRLGIN-GPEEVKNHPWL
|..|..|..   ||..|| ||.||||...|... .... . ..|...||||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 15961.AA Ciliate-E2 454-712 27 4.8e-96 325.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-365/365
Sequence Identity: 27% (103 aa)

FNFHYVIGKGGFG-----KVWKVDS------------------KKTKKVYAMKEMSKSKIITKRSVNSVM----------SERQLLSQLKNPFLVNMNFA
..|. .||.|.||     |||||.                   | ..| |||| |.|..|. . .....|           |...|.||..|....|  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DRENLYLVMDLLTGGDLRFHIGKHR-----------RFSEVQTR---------------FFIACIMMCLEYLHLNN-IIHRDIKPENLVMDDSGYL
||  |..|.||||... ||||. .| ...           .|.| . .               |.||||. .||||| .| ||||||||||...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RVTDLGIAR---------------VWKPENSQDT-------------------SGTPGYMAPEVMCRQN---------HGIAVDYFAVGVIGYEFMMGRR
 ..|.|...                |... ..||                    |||||||||.  ...         .. ..|....||| ||...|..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYLGRSRKEIRDQILAKQVQIKKHE-------------IPDGWSIEAADFINR----MIQRKPMNRLGINGPEEVKNHPWL
|.         .||. ..... . |             ... || |. |.|..    |.|..| .|..  |.|...||||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 15961.AA SGK 454-712 35 6.4e-91 280.97 In-house 1-283 (283) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-283/283
Sequence Identity: 35% (103 aa)

FNFHYVIGKGGFGKVWKVDSKKT------------------KKVYAMKEMSKSKII-------TKRSVNSVMSER-QLLSQLKNPFLVNMNFAFQDRENL
| |  |||||.||||  |  |..                  .|.||||  .|  ||        | ... .|.||  .|. .| ||.||  .|||  . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMDLLTGGDLRFHIGKHRRFSEVQTRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDDSGYLRVTDLGIAR--VWKPENSQDTSGTPGYMAPEVMCRQ
|.||| . ||.. .|. . ..|.| . ||  | |   |||||  .||.|| ||||.. |. |... || | .   . . .      ||| |.||||.  |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

NHGIAVDYFAVGVIGYEFMMGRRPYLGRSRKEIRDQILAKQVQIKKHEIPDGWSIEAADFINRMIQRKPMNRLGIN-GPEEVKNHPWL
 |. .|| .  | . ||.|.|  |.  | ...  |.|. .  ||..     . | .| | |.   |. | .||| . . .|.||||. 
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP-----QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 15961.AA Akt 454-712 38 1.7e-87 279.72 In-house 1-264 (264) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-264/264
Sequence Identity: 38% (104 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVY-AMKEMSKSKIITKRSVNSVMSERQLLSQLKNPFLVNMNFAFQDRENLYLVMDLLTGGDLRFHIGKHRRFSEV
|.| .|.||| ||||  |  |.|.|.| |||  .|..|| |. |  .. || .|   ..||.||....||. ..||.|||   ||.| .|. . ||||| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QTRFFIACIMMCLEYLHLNNIIHRD-IKPENLVMDDSGYLRVTDLGIAR--VWKP-ENSQDTSGTPGYMAPEVMCRQNHGIAVDYFA-VGVIGYEFMMGR
..||..| |.  .|.|| .||| ||  ||||..||  |....|| | ..  . |  .  .   ||| |.|||.   . |. |||  . .|.. ||.| ||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

RPYLGRSRKEIRDQILAKQVQIKKHEIPDGWSIEAADFINRMIQRKPMNRLG--INGPEEVKNHPWL
 |.  . ...  ..|. ..|....    | .| |. |.|... .. | .|||  .|. .|.|.|||.
PPFYNQDHHQMFKKIKNQPVKFPDK---DWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 15961.AA S_TKc 454-712 31 2.6e-85 290.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVYAMKEMSKSKIITKRSVNSVMSERQLLSQLKNPFLVNMNFAFQDRENLYLVMDLLTG--GDLRFHIGKHRR---
. .. .||||.||||.|.  |||....|.|...          .....|.|.|.. . |..|..  .||| ..||.||... |  |||. .| |..|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEVQTRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDDSGYLRVTDLGIARVWKPENSQDTSGTPGYMAPEVMCRQNHGI-AVDYFAVGVIGYEFM
   |.| ..||... |   |||.| ..|||||.||||. .|.   . ..| |.||.          ||| ||||||.    .|  ..|  ..|.| ||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

MGRRPYLGRSRKEIRDQILAKQVQIKKHEIPDGWSIEAADFINRMIQRKPMNRLGINGPEE----VKNHPWL
 |. |.     ... ..|.               | || |||... |. | .|...    .    .|.|||.
CGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15961.AA RSK 457-712 35 8.7e-74 251.44 In-house 1-278 (278) Show / Hide 
Range on Protein: 457-712
Range on HMM: 1-278/278
Sequence Identity: 35% (99 aa)

HYVIGKGGFGKVWKVDSK---KTKKVYAMKEMSKSKIITK-RSVNSVMSERQLLSQLK-NPFLVNMNFAFQDRENLYLVMDLLTGGDLRFHIGKHRR---
. | |.||.|||  .  .   .|...||||  .|.||... ...  .| ||. |.  .  ||.|. . |||. . |||.|... ||.|  |. |...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEVQTRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDD---SGYLRVTDLGIARVWKPENSQDTS---GTPGYMAPEVMC---RQN-HGIAVDYFAVGV
|||   .| .| | . .|.||   |||||.|||| . ||   .| ...|| | ..  .....| |    .|  |||||.     .|. |. |.|..  ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IGYEFMMGRRPYLG---RSRKEIRDQILAKQ--VQIKKHEIPDGWSIEAADFINRMIQRKPMNRLG--INGPEEVKNHPWL
. ||  .|..|. |    .|||| ..|. ..  .   ......  | || |.|..| .| | .|||   .. ||.|.|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSL---TMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 15961.AA AktR 454-712 35 1.1e-72 247.84 In-house 1-268 (268) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-268/268
Sequence Identity: 35% (97 aa)

FNFHYVIGKGGFGKVWKVDSK-KTKKVYAMKEMSKSKIITKRSVNSVMSERQLLS-QLKNPFLVNMNFAFQDRENLYLVMDLLTGGDLRFHIGKHRRFSE
| .. ..|||.||||  |  | ...|.||||  .|.||| ..    .  ||. .  . ..||.|.. ..||..|.|...|.   ||.| .|. | ..|||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

VQTRFFIACIMMCLEYLHLN-NIIHRDIKPENLVMDDSGYLRVTDLGIAR---VW-KPENSQDTSGTPGYMAPEVMCR-QNHGIAVDYFAVGVIGYEFMM
 |.||..| |  .||||| . ||| ||.||||...|  |... || | ..   .  . |  .   ||| |||||.  . . |. .||. |.|.  || ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRRPYLGRSRKEIRDQILAKQ-VQIKKHEIPDGWSIEAADFIN-RMIQRKPMNRLG--INGPEEVKNHPWL
|  |    ..... . |. || ....... .   | .. |.|. .  .. | .|||   ||.||.|.||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYF---SSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 15961.AA CAMK 459-712 20 1.9e-68 219.4 In-house 1-425 (425) Show / Hide 
Range on Protein: 459-712
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

VIGKGGFGKVWKVDSKKTK------------KVYAMKEMSKSKII-------------------------TKRSVNSVMSERQLLSQ-------LKNPFL
..|.|.|||| ..  |.|.            . .|.| ..|.|.                          . ..  .|..| .....       |. | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNMNFAFQD-------------------RENLYLVM---DLLTGG----DLRFHIGKH---------------RRFSEVQTRFFIACIMMCLEYLHLNNI
...  ...|                   ....|.||   .. .||    ||  .| .|               .||.| ..|...  |   ..|.| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLVMDDSG----------------Y-LRVTDLGIARVWKPEN-------------------------SQDTSGTPGYMA-PEVMCRQN----
.|||.||||. .||..                . . ..| | |.. .| .                          ..  |||.||| |||  ..     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------HGIAVDYFAVGVIGYEFMMGRRPYLGRSRKEIR--------DQILAKQVQIKKHE-IPDGWSI-----------------------EAAD
          .| ..|  ..||| |    |. |. | ...||.        |. | ....  | . .|. .|.                       |. |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FINRMIQRKPMNRLGINGPEEVKNHPWL
.|..| |. | .|. |   |...||||.
LIRKMLQVDPEKRMTI---EQCLNHPWM
Kinase 15961.AA Pkinase 454-712 28 1e-64 226.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVYAMKEMSKSKIITKRSVNSVM-SERQLLSQLKNPFLVNMNFAFQDRENLYLVMDLLTGG----DLRFHIG--KH
. .. .||.|.||.|.|   |.| |..|.|...|...  .  .. .  || |..  |. |. | .  .|.|. ..|.||... ||    ||  .|   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRF--SEVQTRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDDSGYL----RVTDLGIAR---VWKPENSQDTSGTPGYMAPEVMC-RQNHGIAVDYFAV
..|  || . .|..  |   |||.| ..|||||.||||. .|. |..    ...| |.|.     . .  ..  |||.||||||   .| .| .|| ...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVIGYEFMMGRRPYLGR--SRKEIRDQILAKQVQIKKHEIPDGWS---------------------IEAADFINRMIQRKPMNRLGINGPEEVKNHPWL
|.| ||.. || |. |.  . . .... . ...  .. . .  |.                      |. |||.......|  |..   .|....|||.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 15961.AA MAST 454-601 37 4.4e-52 157.05 In-house 152-302 (337) Show / Hide 
Range on Protein: 454-601
Range on HMM: 152-302/337
Sequence Identity: 37% (56 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVYAMKEMSKSKIITKRSVNSVMSERQLLSQLKNPFLVNMNFAFQD--RENLYLVMDLLTGGDLRFHIGKHR-RFS
|.|  .|.||..|.|..|  |||.. .||| . .. .| |  |..|..||  |....||| |.|  .||   .. |..||. . |||  ...     .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EVQTRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDDSGYLRVTDLGIARV
|  ... || .  ||||||   |.|||.||.|.. |  | .  || | . |
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKV
Kinase 15961.AA MAST 454-595 40 6.7e-50 158.86 In-house 150-291 (334) Show / Hide 
Range on Protein: 454-595
Range on HMM: 150-291/334
Sequence Identity: 40% (58 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVYAMKEMSKSKIITKRSVNSVMSERQLLSQLKNPFLVNMNFAFQDRENLYLVMDLLTGGDLRFHIGKHRRFSEVQ
|.|  .|.||..|||..|  |||.. .||| . ||  | |  |..|..||  |....||| |.|  .|| ...|..||. . |||. ...    .| |  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDDSGYLRVTD
... || . .||||||   |.|||.||.|.. | .|    ||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTD
Kinase 15961.AA MAST 612-712 39 1.4e-27 85.7 In-house 226-334 (334) Show / Hide 
Range on Protein: 612-712
Range on HMM: 226-334/334
Sequence Identity: 39% (44 aa)

GTPGYMAPEVMCRQN-HGIAVDYFAVGVIGYEFMMGRRPYLGRSRKEIRDQILAKQVQIKK-HEIPDG--------WSIEAADFINRMIQRKPMNRLGIN
|||.|.||||  .|  ||..||....|.| |||. |  |  . .. || ..|| .        |.|.|         | || | |..  |  |  ||| |
GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNC---NEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

-GPEEVKNHPWL
 | .|||.|| .
NGADEVKQHPFF
Kinase 15961.AA MAST 612-712 37 8.9e-27 78.29 In-house 230-337 (337) Show / Hide 
Range on Protein: 612-712
Range on HMM: 230-337/337
Sequence Identity: 37% (42 aa)

GTPGYMAPEVMCRQN-HGIAVDYFAVGVIGYEFMMGRRPYLGRSRKE-IRDQILAKQVQIKKHEIPDG--------WSIEAADFINRMIQRKPMNRLGIN
||| |.||||  .|  .| .||....|.| |||  |  |  | .. | | ..|. ..  |   | |..         | || | |..  |  |  ||| |
GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREI---EWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN

GPEEVKNHPWL
| .|.|.||  
GADEIKQHPFF
Kinase 15961.AA TyrKc 454-706 20 5.6e-13 -12.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 454-706
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FNFHYVIGKGGFGKVWKVDSKKTKKVYAMKEMSKSKIITKRSVNSVMSERQLLSQL--KNPFLVNMNFAFQDR-------ENLYLVMDLLTGGDLRFHIG
  .  ..| | ||.|.|   |   .| | | . ...      .   |.| .....|  ..| .|..  .  .        | |..|| .  .|||. .. 
ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KHRR-FSEVQTRFFIACIMMCLEYLHLNNIIHRDIKPENLVMDDSGYLRVTDLGIARVWKPE------NSQDTS----GTPG-----YMAPEVMCRQNHG
|||. ..  .   |   |    |||| .|.||||.   |   .. .  ...| | .| .. .       .  ..    |. .      ||||..      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

IAVDYFAVGVIGYE-FMMGRRPYLG-----RSRKEIRDQILAKQVQIKKHE--------IPDGWSIEAADFINR-MIQRKPMNRLGINGPEEV
.. | .. ||  .| |  |  || |      | .|.. .. .     . ..         ||       .  ..   .|  .. .     |. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----HECF
Kinase 15961.AA Pkinase_Tyr 454-578 25 1.8e-05 19.13 Pfam 1-137 (270) Show / Hide 
Range on Protein: 454-578
Range on HMM: 1-137/270
Sequence Identity: 25% (36 aa)

FNFHYVIGKGGFGKVWKVDSK-----KTKKVYAMKEMSKSKIITKRS--VNSVMSERQLLSQL-KNPFLVNMNFAFQ-DREN--LYLVMDLLTGGDLRFH
  |  ..|.| ||.|.|   |     .. .| | | . |    ...     . |.| ....|| ..| .|..  .   ..|   .|.|| .  .|||. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IGKH----RRFSEVQTRFFIACIMMCLEYLHLNNIIHRDI
  ||    ....  .   . . | . .|||. .|.||||.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 15961.AA S_TK_X 713-779 25 0.000801 8.55 SMART 1-79 (79) Show / Hide 
Range on Protein: 713-779
Range on HMM: 1-79/79
Sequence Identity: 25% (21 aa)

RNFPWQKLQN--KELESPFVPQSIE---DNYDYRQQISLDDRDTNEDLNQQNGLLLRRNSVQNL----------FAGYNYDG
|.. |.||.|  ||.| ||.|.  |   .  | ..    |.  |.|.   ..      ||...           |.|..|. 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSN---FDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF