Gene 15619 (Tetrahymena)

15619

Species: Tetrahymena
Alias: PreTt15619, 15619, 588, 3692.m00082, 27.m00279, TTHERM_00295090
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
15619.AA Protein None 4112 None Fasta, JSON
15619.kin_dom Protein Kinase Domain None 320 None Fasta, JSON
15619.NA RNA None 12339 None Fasta, JSON

Protein domain

Protein domains of 15619.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15619.AA MAST 3665-3984 48 1.2e-236 731.6 In-house 1-337 (337) Show / Hide 
Range on Protein: 3665-3984
Range on HMM: 1-337/337
Sequence Identity: 48% (165 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILTGDHVVKALYSFQY--DNYLCFVLDYMSGGDFGQILRWYG-RLD
|||......||.|||.||..|.|.|..|.|.|.|....|.||.|....|.|.........|||. ||||.  ..|||.|..||.|||....||.|| ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

ESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLSEVGLTNKLNKKVID---------ETDPEVKKQKMYEQLRQDFGIEGLKNEN
|..||.|.||..|..|||||.||.||||||.|.|.|.||||||.|||||.||...|.......         ....|...||.|.|..|||||.|..|.|
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

FIVQLKQNPGCDLQNSIRPGGIMKKNRVVGTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDESVEK-IFSNIKK--GHIEWPDVGYGE--
.|.|....|.|..||..||..|.......||||||.||||.|..|.....||||.|...|||..|.||||....|. ||.||..   .||||..|...  
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

DEMTPEAQDLIKKLLNHDYKKRLGANGSQEIKQHKFF
|.|.|||||||||||....||||||||..|||||.||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase 15619.AA MAST 3665-3984 48 9.1e-217 705.8 In-house 1-334 (334) Show / Hide 
Range on Protein: 3665-3984
Range on HMM: 1-334/334
Sequence Identity: 48% (164 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILTGDHVVKALYSFQYDNYLCFVLDYMSGGDFGQILRWYGRLDESI
|||..... ||.|.|.||..|.|.| .|.|.|..|.....|..|....|.|..|......|||. ||||..||||.|..||.|||....|..||..||..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLSEVGLTNKLNKKVID---------ETDPEVKKQKMYEQLRQDFGIEGLKNENFIV
||.|.||..|..|||||.||.||||||.|.|.|.||||||.|||||.||....||.....         .|||..|.|..|.|...||||.|..|.|.|.
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

QLKQNPGCDLQNSIRPGGIMKKNRVVGTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDESVEKIFSNIKKGH---IEWPDVGYGE--DEM
|....|.|..|| .||..|.......||||||.||||.|..|.....||||.|...|||..|.|||||...|.||.||.. .   ||||..|...  ..|
QQQEQPQCQQQN-MRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAM

TPEAQDLIKKLLNHDYKKRLGAN-GSQEIKQHKFF
.|||||||.|||..|..|||||| |..|.|||.||
SPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 15619.AA AGC 3665-3984 28 1.2e-160 419.04 In-house 1-395 (395) Show / Hide 
Range on Protein: 3665-3984
Range on HMM: 1-395/395
Sequence Identity: 28% (123 aa)

FEFKRLLGVGAFGAVWLVNKK------TTKDEYALKIIDCSQ--------QMDRNQQDN-------LRAETNVFAILTG----------DHVVK-ALYSF
|||....| |.|| |.|| ||      .|.. ||.|... .         ......  .       ...| |... . .          . .||   |||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QYDNY--LCFVLDYMS---------GG-DFGQILR---WYGRLDESIAKFYLAE-------IILAIEYLHS-KGIIHRD-LKPENVLLDKNGHIKLADFG
| ...  |.||..||.         || .. ..|.    .||.||. |.||.||       |.||.||||| .|||||| |||||.|||..|||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSEVGLTNK----------LNKKVIDETDPEVKKQKMYEQLRQDFGIEGLKNENFIVQLKQNPGCDLQNSIRPG----------GIMKKNRVVG--TPDY
|. .| ...          ....  ...  . |.                   |.    . |  |...|  | .          .  . .  .|  ||.|
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-------------------NMD---T-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEY

IPPEVINGESTNNQSIDWWS--LGVMVYEFIAGIPPFNDESVE----------KIFSNIKKGH--IEWPDVGY--------GEDEMTPEAQDLIKKLLNH
..||..      ... ||||  ||.. ||...|.|||......          ..| .|..|.  |.|.            ......|||.|||||||. 
MAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCK

DYKKRLGAN-------GSQEIKQHKFF
| .||||..       | .|||.|..|
DPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 15619.AA NDR 3665-3984 34 4.8e-123 381.54 In-house 1-350 (350) Show / Hide 
Range on Protein: 3665-3984
Range on HMM: 1-350/350
Sequence Identity: 34% (123 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILT--GDHVVKALYSFQYDNYLCFVLDYMSGGDFGQ---ILRWYGR
||. ...|.|||| |||| || |.. ||.||.  |  |..|| ...|||  ..|.     . |||..|||| ..||..| .|. |||..    .|  .. 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLSEVGLT-----NKLNKKVIDETDPEVKKQKMYEQLRQDFGIEGLKNENFI
..|..|.|| ||...|||..|. |.||||.||.| |.|| ||||| ||||.  |..     ..  || .  |     ... .... |  .........|.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPM-TTYST-FHWTHNSWYYQ--NMKEHRPQDFM

VQLKQNPGCDLQNSIR-----------PGGIM--------KKNRVVGTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDESVEKIFSNIKK
   ..||  .. ....           . ...        . ...||||||..|||....  .||..||||||.. ||.. |.|||......... .|..
DNWNSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMN

GHIEW--PDVGYGEDE-MTPEAQDLIKKLLNHDYKKRLGANG--SQEIKQHKFF
  . |  | ....... ..|||.|||..|.. | ..|||..|   .|||.| ||
WKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 15619.AA S_TKc 3665-3984 28 1e-89 305.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 3665-3984
Range on HMM: 1-231/231
Sequence Identity: 28% (94 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILTGDHVVKALYSFQYDNYLCFVLDYMSG--GDFGQILRWYGR---
.|. |..| |||| |... .| |. ..|.|||.          ...| | ..      ...|| ...||  ..|..|..|..|  ||  .... .||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLSEVGLTNKLNKKVIDETDPEVKKQKMYEQLRQDFGIEGLKNENFIVQ
   ..|  |.||...|..|.||.||.|||||||||||.|||.  |||..||||. .                                            
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

LKQNPGCDLQNSIRPGGIMKKNRVVGTPDYIPPEVINGESTNNQ-SIDWWSLGVMVYEFIAGIPPFNDESVEKIFSNIKKGHIEWPDVGYGEDEMTPEAQ
                     . ..|||.|..|||.      .  ..||||.|...||...| |||    ....| .|.                .||| 
---------------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------SPEAK

DLIKKLLNHDYKKRLGANGSQE----IKQHKFF
|.|.|.|. | .||..|    .    ||.| .|
DFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15619.AA AktR 3665-3984 31 4.4e-87 295.61 In-house 1-268 (268) Show / Hide 
Range on Protein: 3665-3984
Range on HMM: 1-268/268
Sequence Identity: 31% (107 aa)

FEFKRLLGVGAFGAVWLVNKK-TTKDEYALKIIDCSQQMDRNQQDNLRAETNVFA-ILTGDH--VVKALYSFQYDNYLCFVLDYMSGGDFGQILRWYGRL
|.. ..|| |||| | || || .... ||.|.|. .   .|||.. .. | |. . .   .|   ||  |.|| ...| |...|. ||.  |.|.  ...
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCC--NHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKF

DESIAKFYLAEIILAIEYLHSK-GIIHRDLKPENVLLDKNGHIKLADFGLSEVGLTNKLNKKVIDETDPEVKKQKMYEQLRQDFGIEGLKNENFIVQLKQ
.|. |.|| |.|.||.||||..  || ||||||| |||..||.|..|||||.                                                
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK------------------------------------------------

NPGCDLQNSIRPGGIMKKN-R------VVGTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDESVEKIFSNIKKGH-IEWPDVGYGEDEMT
              . ... .      ..||| |..||.|. .   | |.|||..|. .|| ..|.|||.... . .| .||.   .. |.  |     .
--------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSY----FS

PEAQDLIK-KLLNHDYKKRLG--ANGSQEIKQHKFF
....|||. |||. . .||||  .|| .||| |..|
SQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 15619.AA RSK 3668-3984 28 1.6e-77 263.82 In-house 1-278 (278) Show / Hide 
Range on Protein: 3668-3984
Range on HMM: 1-278/278
Sequence Identity: 28% (95 aa)

KRLLGVGAFGAVWLVNKK---TTKDEYALKIIDCSQQMDRNQ-QDNLRAETNVFAILT-GDHVVKALYSFQYDNYLCFVLDYMSGGDFGQILRWYGR---
 ..|| |..|.| |. |.    |. .|| |... .  . |.  .   ..| |. .  .    .|.  |.|| . .|  ...|..||...  |.  ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDK---NGHIKLADFGLSEVGLTNKLNKKVIDETDPEVKKQKMYEQLRQDFGIEGLKNENFIVQ
..|. |.||.|||.||.|.||..|||||||||||.|.|    .||||| |||..  .                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

LKQNPGCDLQNSIRPGGIMKKNRVVGTPDYIPPEVIN---GESTNNQSIDWWSLGVMVYEFIAGIPPFND---ESVEKIFSNIKKGHIEWPDVGYG-EDE
           ... .. ...   ..| .|..||...   .... ... |||||||  ||  .| |||     .. ..|. .|.||..   ... .  ..
-----------RCDHNQWTMT--FCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKF---SLTMPNWQY

MTPEAQDLIKKLLNHDYKKRLG--ANGSQEIKQHKFF
...||.|||.|.|  | .||||   .. .|||||..|
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 15619.AA Akt 3665-3810 47 1.1e-62 199.23 In-house 1-148 (264) Show / Hide 
Range on Protein: 3665-3810
Range on HMM: 1-148/264
Sequence Identity: 47% (70 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEY-ALKIIDCSQQMDRNQQDNLRAETNVFAILTGDHVVKALYSFQYDNYLCFVLDYMSGGDFGQILRWYGRLDES
|.|...|| |.|| | || || |.. | |.|..  ..  ..||  .  .| |.        .|.  ||||  ..|.||.||..||.  . |.  .| .|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

IAKFYLAEIILAIEYLHSKGIIHRD-LKPENVLLDKNGHIKLADFGLS
 |.|| ||||||||.||||.|| || |||||.|.||.|||.|.||||.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase 15619.AA SGK 3665-3810 34 7.8e-57 173.83 In-house 1-172 (283) Show / Hide 
Range on Protein: 3665-3810
Range on HMM: 1-172/283
Sequence Identity: 34% (59 aa)

FEFKRLLGVGAFGAVWLVNKKTT------------------KDEYALKIIDCSQQM-------DRNQQDNLRAET-NVFAILTGDHVVKALYSFQYDNYL
|.|. ..| | || | .| .| .                  .. ||.|..   .          ...| .  ||  ..   .     |.  |.|| . .|
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CFVLDYMSGGDFGQILRWYGRLDESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLS
 ||.||. ||. .  |.  ... |. |.|| |||..|.|||||. ||.|||||||.|||  ||..| ||||.
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase 15619.AA RSK-Unclassified 3665-3810 37 6.4e-53 164.29 In-house 1-148 (283) Show / Hide 
Range on Protein: 3665-3810
Range on HMM: 1-148/283
Sequence Identity: 37% (56 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILTGDHVVKALYSFQYDNYLCFVLDYMSGGDFGQILR--WYGRLDE
|.  ||.| | || |.|| || |.  ||.|.   .. . .|       | |. |.     .|.  .|||   ||  ...|  ||||.. |      .. |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

SIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLS
  ..||..|...| |||| ...| |||||.|..|.. ||..| ||.||
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLS
Kinase 15619.AA Pkinase 3665-3812 34 2.5e-47 168.34 Pfam 1-161 (293) Show / Hide 
Range on Protein: 3665-3812
Range on HMM: 1-161/293
Sequence Identity: 34% (55 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLR-AETNVFAILTGDHVVKALYSFQYDNYLCFVLDYMSGG----DFGQILR--WY
....| .| |.|| |..  .| | ...|.|||. . . .  .| ..| .|  . . |  ...|. ...|........|..|. ||    |   ...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--DESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHI----KLADFGLSEV
|..  .|  .|||. .|. ..||.||.|||||||||||.|.|.||||    |..||||...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQ
Kinase 15619.AA PKA 3665-3808 43 2.5e-47 163.54 In-house 105-250 (263) Show / Hide 
Range on Protein: 3665-3808
Range on HMM: 105-250/263
Sequence Identity: 43% (64 aa)

FEFKRLLGVGAFGAVWLVNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAILTGDHVV-KALYSFQYDNYLCFVLDYMSGGDFGQILRWYGRLDES
||....|| | || | |. .|.... ||.|... ..  ...|..    | |.   ..   .| |  ..|| |.|| .|..| .||.    ||  ||....
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

IAKFYLA-EIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFG
.|||| | .|.||.|||||. ||.||||||| |.|||||||..|||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG
Kinase 15619.AA PKA 3882-3984 40 1.5e-35 124.46 In-house 160-263 (263) Show / Hide 
Range on Protein: 3882-3984
Range on HMM: 160-263/263
Sequence Identity: 40% (45 aa)

GTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDE--SVEKIFSNIKKGHIEWPDVGYGEDEMTPEA---QDLIKKLLNHDYKKRLG--ANG
|||.|..||.|...   . |.|||.||. .||. ||.|||.|.  .. .|.  | .| |..|       .... |    |||||||. | .||.|   ||
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPR------HFDSDANYFKDLIKKLLQVDLTKRYGNMKNG

SQEIKQHKFF
.. || ||.|
VNDIKNHKWF
Kinase 15619.AA SGK 3882-3984 38 7.7e-35 104.67 In-house 187-283 (283) Show / Hide 
Range on Protein: 3882-3984
Range on HMM: 187-283/283
Sequence Identity: 38% (40 aa)

GTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDESVEKIFSNIKKGHIEWPDVGYGEDEMTPEAQDLIKKLLNHDYKKRLGAN-GSQEIKQ
||| |  |||.... .   . |||.||   ||.. |.||| .  ..  . || .. .  |        |...| |||. ||. | |||||.. .. |||.
GTPEYLAPEVLRKQ-PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIP------PQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKN

HKFF
| ||
HPFF
Kinase 15619.AA Akt 3880-3984 42 2.8e-33 103.66 In-house 162-264 (264) Show / Hide 
Range on Protein: 3880-3984
Range on HMM: 162-264/264
Sequence Identity: 42% (46 aa)

VVGTPDYIPPEVINGESTNNQSIDWWS-LGVMVYEFIAGIPPFNDESVEKIFSNIKKGHIEWPDVGYGEDEMTPEAQDLIKKLLNHDYKKRLG--ANGSQ
. ||| |..||..||     .. |||. ||.  ||.. | ||| .. ... | .|| . .. ||     |   ||..|||..||| |.|||||   |. |
FCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPD----KDWISPECKDLISGLLNKDPKKRLGGGPNDAQ

EIKQHKFF
|||.| .|
EIKRHPWF
Kinase 15619.AA RSK-Unclassified 3881-3984 36 7.3e-31 93.78 In-house 183-283 (283) Show / Hide 
Range on Protein: 3881-3984
Range on HMM: 183-283/283
Sequence Identity: 36% (39 aa)

VGTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDESVEKIFSNIKKGHIEWPDVGYGEDEMTPEAQDLIKKLLNHDYKKRLGA-NG-SQEI
.|| .|. ||.| .       .||| ||...||   |.||.  .  . .|.|| |.|.  |.    . ..  ...|||||||.    ||||.  |  ..|
CGTEEYLAPEMIRR-CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPH----DSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDI

KQHKFF
|.| ||
KRHPFF
Kinase 15619.AA Pkinase 3880-3984 25 1e-25 91.99 Pfam 171-293 (293) Show / Hide 
Range on Protein: 3880-3984
Range on HMM: 171-293/293
Sequence Identity: 25% (33 aa)

VVGTPDYIPPEVINGESTNNQSIDWWSLGVMVYEFIAGIPPFNDE------SVEKIFSNIKKGHIEWPDVGY----------------GEDEMTPEAQDL
..|||.|..||||.| .   ...|.||.|...||.. | ||| ..      .  ... .|... ....                      .....|..|.
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDF

IKKLLNHDYKKRLGANGSQEIKQHKFF
||..|. | |||..    ..|.||..|
IKWCLCKDPKKRPT---AEQILQHPWF
Kinase 15619.AA TyrKc 3665-3869 17 2.6e-11 -39.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 3665-3869
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FEFKRLLGVGAFGAVWL-VNKKTTKDEYALKIIDCSQQMDRNQQDNLRAETNVFAIL--TGDHVVKALYSFQYD-------NYLCFVLDYMSGGDFGQIL
 .... || |||| |.. . |     . | | .  .       .  .. | ..   |    ...|. .     .         |. |. ||..||  . |
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

RWYGR-LDESIAKFYLAEIILAIEYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLSEVGL----------TNKL----NKK-----------VIDET--
| ... |  .    .   |    ||||||..|||||   |.|...|...| .|||||  .           . .     ..|           .|..   
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

-----------------------DPE-----VKKQKMYEQLRQDFGIEGLKN---------ENFIVQL-----KQNPGC-----DLQNSI
                        |.     .. | ..|...| .  .  .|            . |.     . .| .     ..   .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 15619.AA Pkinase_Tyr 3777-3810 52 2.2e-09 32.38 Pfam 125-158 (270) Show / Hide 
Range on Protein: 3777-3810
Range on HMM: 125-158/270
Sequence Identity: 52% (18 aa)

EYLHSKGIIHRDLKPENVLLDKNGHIKLADFGLS
|||.||..|||||   |.|...|...| .||||.
EYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 15619.AA Pkinase_Tyr 3665-3681 47 0.033709 8.07 Pfam 1-17 (270) Show / Hide 
Range on Protein: 3665-3681
Range on HMM: 1-17/270
Sequence Identity: 47% (8 aa)

FEFKRLLGVGAFGAVWL
 .| . || |||| |..
ITFGKKLGEGAFGEVYK