Gene 26485 (Tetrahymena)

26485

Species: Tetrahymena
Alias: 3831.m01586, TTHERM_00433420, PreTt26485, 26485, 107, 48.m00248
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
26485.AA Protein None 319 None Fasta, JSON
26485.NA RNA None 960 None Fasta, JSON
26485.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 26485.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26485.AA PKA 12-266 64 7.6e-199 666.88 In-house 1-263 (263) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-263/263
Sequence Identity: 64% (170 aa)

YEIFQTLGTGSFGRVKLAKKKNTTQYVALKVLKKAEIIRLKQVDHIINENTILSNLNHPFIV-KMDGFCQDSRYLYLVLEFVSGGELFTYLRSVGRLETN
.||.|||||||||||.|...|....|.|.|.|||.||.|||||.|..||..||.|..||||| ||....||.||||.|.|.|.|||.|.||| .||.   
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

HACFYAA-QVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAKVVEGRTYTLCGTPEYLAPEILLNK-GHGKAVDWWTLGILIYEMNAGIDPFT
||.|||| |..|..||||..|||||||||||.|| ..|..|.||||||| |..||.|||||||||||||...| ||||.||||.|||||||| ||..||.
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

DE--DPMAIYQKILKGKVKFPRNFDKNA---KSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
|.  |||.||.||..||.||||.||..|   |.|.|.||..||.|||||.|||.||||||.||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 26485.AA AGC 12-266 34 1.2e-175 458.71 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-395/395
Sequence Identity: 34% (136 aa)

YEIFQTLGTGSFGRVKLAKKKN-----TT-QYVALKVLKKAE-IIRLK--QVDHIINE------------NTILSNLN----------HPFIVK-MDGFC
.|.  ..|.||||.| |..||.     .| .| |.|||||.. |...|  .|.|...|              ||...|          |||||| .    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDSRY--LYLVLE----FVS-----GG-ELFTYLR---SVGRLETNHACFYAAQ-------VTLMFEYLHT-KNIIYRD-LKPENLLIADDGYLKLTDFG
|| ..  ||.|.|    .|.     || |||..|.     ||.. ..|.||||.       ..| .||||  ..||.|| |||||.|. .||..||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKVVEG-----------------------------------------------------RTYTLCG--TPEYLAPEILLNKGHGKAVDWWT--LGILIY
..|.. .                                                     ||.|.||  ||||.|||||    .|||.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMNAGIDPFTDE----------DPMAIYQKIL------KGKVKFP----------RNFDKNAKSLVKHLLVADLSKRYGNLKN-----GANDIKNHRWF
|| .|. ||...          .|| ..|||.      . |||||          |.|...||.|.|.||. | .|| |...|     ||..|||| ||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 26485.AA Akt 12-266 46 1.1e-119 384.25 In-house 1-264 (264) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-264/264
Sequence Identity: 46% (124 aa)

YEIFQTLGTGSFGRVKLAKKKNTTQYV-ALKVLKKAEIIRLKQVDHIINENTILSNLNHPFIVKMDGFCQDSRYLYLVLEFVSGGELFTYLRSVGRLETN
 ..   || ||||.| |.|||.| ..  |.|||||  ||  .|| |.. |. || . ||||||..    |.. .||.|.....|||||..|.  .|   .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

HACFYAAQVTLMFEYLHTKNIIYRD-LKPENLLIADDGYLKLTDFGFAK--VVEG--RTYTLCGTPEYLAPEILLNKGHGKAVDWWT-LGILIYEMNAGI
 | ||.|.. |  |.|| ||||||| |||||.|.  ||...||||| .|  ..    .|.|.||||||||||||...||.||||||. ||...|||  | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

DPFTDEDPMAIYQKILKGKVKFP--RNFDKNAKSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
 || ..|    ..||. ..||||  .......|.|.. ||  | .|| |. .|.|..||.| ||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 26485.AA AktR 12-266 42 4.7e-117 395.17 In-house 1-268 (268) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-268/268
Sequence Identity: 42% (114 aa)

YEIFQTLGTGSFGRVKLAKKK-NTTQYVALKVLKKAEIIRLKQVDHIINENTILS-NLNHPFIVKMDGFCQDSRYLYLVLEFVSGGELFTYLRSVGRLET
... . || | ||.| |..|| .. ...|.|..|| .||...| .|.|.| .|.    |||||||.  . |. ..|....|.. |||||..|.. .... 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

NHACFYAAQVTLMFEYLHTK-NIIYRDLKPENLLIADDGYLKLTDFGFAK---V--VEGRTYTLCGTPEYLAPEILLN-KGHGKAVDWWTLGILIYEMNA
. | ||.||. |..|||| . |||||||||||.|.  ||..|.|||| .|   .   . ..|..||||||.|||.... |||.|.||||..||.|||| .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GIDPFTDEDPMAIYQKILKGK-VKFPRN--FDKNAKSLVK-HLLVADLSKRYGNLKNGANDIKNHRWF
|. ||....   ..|||..   .||| .  | ...|.|..  ||  .  || |  .||. .||.| ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 26485.AA SGK 12-266 37 7.29999999999e-110 340.53 In-house 1-283 (283) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-283/283
Sequence Identity: 37% (107 aa)

YEIFQTLGTGSFGRVKLAKKKNT------------------TQYVALKVLKKAEII-------RLKQVDHIINEN-TILSNLNHPFIVKMDGFCQDSRYL
 .. ...| ||||.| ..|.| .                   .  |.|||.|. ||       . |.. ||  |  .||.|..|||||.     |   .|
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVLEFVSGGELFTYLRSVGRLETNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAK---VVEGRTYTLCGTPEYLAPEILLNK
|.|...| |||.| .|.  ...    | ||||.. .  |||| ..||||||||||.|  ..|...||||| .|     .  | | ||||||||||.|. .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHGKAVDWWTLGILIYEMNAGIDPFTDEDPMAIYQKILKGKVKFPRNFDKNAKSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
.|...|||| ||.. |||  |. || . .    |..|.... ..|...   |..| . ||  | .|| |  |... .|||| .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF
Kinase 26485.AA PKG 12-266 46 2.4e-105 356.31 In-house 1-260 (260) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-260/260
Sequence Identity: 46% (121 aa)

YEIFQTLGTGSFGRVKLAKKKNTT-QYVALKVLKKAEIIRLKQVDHIINENTILSNLNHPFIVKMDGFCQDSRYLYLVLEFVSGGELFTYLRSVGRLETN
 .|  ||| | |||| | . ..   .  |||..||..|.  .| .||..|  |.  .. .|||..     |..|.|. .|   |||| | ||  |. . .
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

HACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAKVVE--GRTYTLCGTPEYLAPEILLNKGHGKAVDWWTLGILIYEMNAGIDPFT
 . ||.| |.  |.||| |||||||||||||. . .||.|| |||||| ..  ..|.| |||||| |||| |||||  .||.| ||||..|   |  ||.
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

DEDPMAIYQKILKG--KVKFPRNFDKNAKSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
  ||| .|. ||||  .. |||.  ..|. ..|.|     . | |..||| |||| |.||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase 26485.AA RSK 15-266 40 5.6e-98 331.82 In-house 1-278 (278) Show / Hide 
Range on Protein: 15-266
Range on HMM: 1-278/278
Sequence Identity: 40% (113 aa)

FQTLGTGSFGRVKLAKKK---NTTQYVALKVLKKAEIIRLKQ-VDHIINENTILSNLN-HPFIVKMDGFCQDSRYLYLVLEFVSGGELFTYLRSVGR---
 . ||.|..| | | .|.   .| |. | ||||||.|.. .  . |   | .||.  . |||||.     |.  .|||..|...|||||| |.  ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LETNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIAD---DGYLKLTDFGFAKV--VE--GRTYTLCGTPEYLAPEILL----NKGHGKAVDWWTLGI
.  . ||||.|...|  |.||.. ||.||||||| | .|   .| .|||||||.|    .  ..|.| |.| ||.|||.|     ..||.||.|||.||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMNAGIDPFTD---EDPMAIYQKILKGK--VKFP--RNFDKNAKSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
|.||| .|  ||.    ...  | ..|.|||  ...|   .  ..||.|....|  | .||.|  ...|..||.| ||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 26485.AA S_TKc 12-266 36 1.5e-95 324.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YEIFQTLGTGSFGRVKLAKKKNTTQYVALKVLKKAEIIRLKQVDHIINENTILSNLNHPFIVKMDGFCQDSRYLYLVLEFVSG--GELFTYLRSVGR---
||| ...| |.||.|.....|.| ..||.|..|          .||..|  ||.. .||.|||. ...||  .||.|.|...|  |.||.|... ||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LETNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAKVVEGRTYTLCGTPEYLAPEILLNKGHGK-AVDWWTLGILIYEMNA
   .   ||.||..|. .  ||.| ..||.|||||||.|. .   .|..|||.|...    .|.||||.|.|||.|   |.|| ..||| .|...||| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GIDPFTDEDPMAIYQKILKGKVKFPRNFDKNAKSLVKHLLVADLSKRYGNLKNGA--NDIKNHRWF
|  ||   .......||.          .. ||......|. | .||..  .  .   |||.| ||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26485.AA Ciliate-E2b 12-266 38 2.5e-95 290.09 In-house 1-272 (272) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-272/272
Sequence Identity: 38% (108 aa)

YEIFQTLGTGSFGRVKLAKK-KNTTQYVALKVLKKAEIIRLKQVDHIINENTILSNLNHPFIVKMDGFCQDSRYLYLVLEFVSGGELFTYLRSVG--RLE
 ..   || | || | | .. ||| || |.|. .|..||     .|...|  .|  .|||||.|     .|....|...||..|.|||...| .|   | 
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

TNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAKVVE---G---RTYTLCGTPEYLAPEILL-----NKGHGKAVDWWTLGILI
|. . || |.. | .||||..||||||.|||| ..  .||.|| |.| ||. .   .   ||.|..|||.|.||||.      .|| . .|| | .||  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YEMNAGIDPFTD--EDPMAIYQKILKG--KVKFPRNF-DKNA-KSLVKHLL----VADLSKRYGNLKNGANDIKNHRWF
||.  |  |..   .||  |||.|.|.  ...||  . ||.| |.|.  .|    . .| ..|. |       |.| ||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWL-------KSHPWF
Kinase 26485.AA Pkinase 12-266 31 5.8e-89 306.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YEIFQTLGTGSFGRVKLAKKKNTTQYVALKVLKKAEIIRLKQVDHII-NENTILSNLNHPFIVKMDGFCQDSRYLYLVLEFVSGG----ELFTYLR--SV
|.| ...| ||||.|.....|.| . ||.|..|| ..   |.. |.  .|  |. .||||.||.. ....|....|.|.|.. ||    .||.|..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--ETNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYL----KLTDFGFAK---VVEGRTYTLCGTPEYLAPEILL-NKGHGKAVDWWTLG
|..  . ....||. |.    ||.| ..||.|||||||.|| ..|..    |..|||.||      ....|.||||.|.|||... ....|..||.| .|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

ILIYEMNAGIDPFTDE------DPMAIYQKILKGKVKFPRNFD---------------------KNAKSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
...|||  |  || ..      |.|.....|......|..  .                     ...|...| .|  | .||..     | .|..| ||
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase 26485.AA Ciliate-E2 12-266 26 1e-88 301.01 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-365/365
Sequence Identity: 26% (103 aa)

YEIFQTLGTGSFGRVKLAKK-----------------------KNTTQYVALKVLKKAEIIRLKQVDHII----------NENTILSNLNHPFIVKMDGF
|.. . .|.|.|| |...|.                       |.. ...|.|..|| .|. .||..||.          ||  ||..||||.|.||  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CQ--DSRYLYLVLEFVSGGELFTYLR-------------------SVGRLETNHAC-------FYAAQVTLMFEYLHTKN-IIYRDLKPENLLIADDGYL
 |  |  ..|||.|...||.|| |..                    .... .  .        ||.|.. | .|||| || ||.||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGFAK----------------------------------VVEGRTYTLCGTPEYLAPEILLNKG---------HGKAVDWWTLGILIYEMNAGIDP
|..|||..|                                  . .  ..|.||||.|.||||| .|.         .....|.| ||...|||  |  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FTDEDPMAIYQKILKGKVKFPRN------------------FDKNAKSLVKH----LLVADLSKRYGNLKNGANDIKNHRWF
|        .|.|...|..|| .                   ....| | |     .|. | .||..    |...|.|| ||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF
Kinase 26485.AA RSK 12-266 37 4.5e-86 292.27 In-house 1-271 (271) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-271/271
Sequence Identity: 37% (103 aa)

YEIFQTLGTGSFGRVKLAKKK---NTTQYVALKVLKKAEIIRLKQVDHIINENTILSNLNHPFIVKMDGFCQDSRYLYLVLEFVSGGELFTYLRSVGRLE
||. . .|.|||. | . ||.    | |. | |..||| .    . .   .|  ||.. .||||||     || ...|....|  ||.||. |  .. . 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

TNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADD----GYLKLTDFGFAKVV---EGRTYTLCGTPEYLAPEILLNKGHGKAVDWWTLGILIYEMN
 . ..||.| ..|  ||||.. |..||||||| |..|.    | .|..|||||| .   .| ..| |.| .|.|||.|  .||..|.||| .|.| ||| 
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

AGIDPF---TDEDPMAIYQKILKGKVKF----PRNFDKNAKSLVKHLLVADLSKRYGNLKNGANDIKNHRWF
.|  ||   ....||.| |.|  |.  .    . .  . ||.|. ..|  |  .|.|.  ||...||.| ||
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 26485.AA Pkinase_Tyr 12-160 31 6.3e-19 64.72 Pfam 1-161 (270) Show / Hide 
Range on Protein: 12-160
Range on HMM: 1-161/270
Sequence Identity: 31% (51 aa)

YEIFQTLGTGSFGRVKLAKKK----NTTQYVALKVLKKAEIIRLKQ--VDHIINENTILSNL-NHPFIVKMDGFCQ-DSRY--LYLVLEFVSGGELFTYL
 .. ..|| |.||.|.... |    ||.. || |.||  |    .|   .  ..|  |...| .|| ||.. | |  ...   .|.|.|.. .| | .||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RS----VGRLETNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAKVV
|.     ..| . . . ...|.    |||. ||.| |||   | |.....  | .||| |. .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase 26485.AA TyrKc 12-253 21 1.1e-15 30.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-253
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

YEIFQTLGTGSFGRVKLAKKKNTTQYVALKVLKKAEIIRLKQVDHIINENTILSNL--NHPFIVKMDGFCQDS-------RYLYLVLEFVSGGELFTYLR
 .  ..|| | ||.| ... |   . || |.||.        .  ...|  |...|  .|| ||.. | | ..         |..|.|....| |  |||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SVGR-LETNHACFYAAQVTLMFEYLHTKNIIYRDLKPENLLIADDGYLKLTDFGFAKVVEGR-------TYTLC----GTPE-----YLAPEILLNKGHG
. .. | . . . .. |.    |||| ||.| |||   | |.....  | .||| .. ..          |       |.        .||| .  .   
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWTLGILIYEMNAGIDPFTDE------DPMAIYQKILKG-KVKFPRN--------FDKNAKSLVKHLLVADLSKR------YGNL
 . | |  |....|.    ..   .      ..  ..... .|   . | |          .   .. |    .| ..|      .  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 26485.AA S_TK_X 267-319 26 1e-06 29.52 SMART 1-75 (79) Show / Hide 
Range on Protein: 267-319
Range on HMM: 1-75/79
Sequence Identity: 26% (21 aa)

SSIDWAQLLS--KKLPVPYKPVVK----APNDTSNFS-SYPE-SDTHSPALKPADD------------------PFLDW
..||| .|..  |... |.|| .|     | |||||   ..| ...    |.|.|.                  ||...
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM----LTPDDPPLSNSMWQNEMETEIPPDPFRGF